Honorary Professor Marta C Cohen MD,Marta Cohen FRCPath, DMJ (Pathol), Dip Med Education

Department of Oncology and Metabolism
The University of Sheffield
The Medical School
Beech Hill Road
Sheffield
S10 2RX
UK

Histopathology Department, Sheffield Children’s NHS FT Western Bank, Sheffield S10 2TH
Office

Tel: +44 (0) 114 271 7486
Fax: +44 (0) 114 271 7365
email: Marta.Cohen@nhs.net

Biography

I joined the University of Sheffield in 2003 and have been closely involved in education of both medical students and post graduate doctors. I been privileged to be part of numerous research projects in conjunction with lead researchers from the University of Sheffield.

I am currently Head of Department of Histopathology and Clinical Director of Pharmacy, Pathology and Genetics, Sheffield Children’s NHS FT. I am also Academic Lead for the Specialty Advisory Committee on Prenatal, Perinatal and Paediatric Pathology for the Royal College of Pathologists; Editorial Board Member of the International Society for the Study and Prevention of Perinatal and Infant Death (ISPID) and Editorial board member of the Journal Pediatric and Developmental Pathology

Research Interests

My research interests are prenatal, perinatal and sudden infant death investigation, the placenta and paediatric gastrointestinal pathology.

Teaching Interests

I hold a Diploma in Medical Education and have an invested interest in medical education. I supervise medical students during clinical attachments in my department, and I am the Chair and Programme Director of Advanced Training Centre for Paediatric and Perinatal Pathology of European Society of Pathology; Educational Supervisor of trainees; Course Director of International Paediatric Pathology Association’s Post-Graduate Advanced Course (2014 – 2018); Course Director of the next Update Course of the International Paediatric Pathology Association’s Post-Graduate Advanced Course (2020) and involved in the development of educational tools, such as e learning modules, websites and books.

Current projects

  • NIHR Global Health Research Group on PReterm bIrth prevention and manageMEnt (PRIME).
  • Prevalence of occult bone disease due to vitamin D deficiency in SUDI in childhood: A post mortem study.
  • Fatty oxidation flux can be a surrogate marker of mitochondrial respiratory chain disease in sudden unexplained death in infancy (SUDI) and Childhood (SUDC): Chief Investigator
  • Utility of post-mortem computed tomography and magnetic resonance imaging for assessing cause of death, developing finite element models and understanding bone pathophysiology in children: Principal Investigator
  • Could the distribution of mast cells help to define and categorise the nature of the eosinophilic oesophagitis and eosinophilic colitis in the paediatric population?
  • An investigation of the relationship between the result of the routine newborn hearing screening test and the risk of unexpected infant death
  • Identification of genetic risk in unexplained sudden death syndrome utilising a genome wide methodology

Key publications

  1. Post-mortem microbiology in Sudden Death: Sampling protocols proposed in different clinical settings. Fernández-Rodríguez, Amparo; Burton, Julian; Andréoletti, Laurent; Alberola, Juan; Fornes, Paul; Merino, Irene; Martínez, Miguel; Castillo, Paola; Sampaio-Maia, Benedita; Caldas, Inês; Saegeman, Veroniek; Cohen, Marta. Clinical Microbiology and Infection (Official Journal of ECCMID) 2019; 25 (5): 570-579
  2. Non-Cardiac Genetic Predisposition in Sudden Infant Death Syndrome. Gray B, Tester DJ, Wong LC, Chanana P, Jaye A, Evans JM, Baruteau AE, Evans M, Fleming P, Jeffrey I, Cohen M, Tfelt-Hansen J, Simpson MA, Ackerman MJ, Behr ER. Genet Med. 2019, 21: 641-649
  3. Dysfunction of NaV1.4, a skeletal muscle voltage gated sodium channel in sudden infant death syndrome. R. Männikkö, L. Wong, D. Tester, M.G. Thor, R. Sud, D.M. Kullmann1, M.G. Sweeney, C. Leu, S.M. Sisodiya, D.R. Fitzpatrick, M.J. Evans, I.J.M. Jeffrey, M.C. Cohen, P.J. Fleming, A. Jaye, M. A. Simpson, M.J. Ackerma N, M.G. Hanna, E.R. Behr and E. Matthews The Lancet 2018; 391: 1483-92
  4. Exome-wide Rare Variant Analyses in Sudden Infant Death Syndrome. David J. Tester, Leonie CH Wong, Pritha Chanana, Belinda Gray,Amie Jaye, Jared M. Evans, David FitzPatrick, Margaret Evans, Peter Fleming, Iona Jeffrey, Marta Cohen, Jacob Tfelt-Hansen, Michael A Simpson, Elijah R Behr, Michael J Ackerman. J of Pediatrics 2018; 203: 423-428
  5. Cardiac Genetic Predisposition in Sudden Infant Death Syndrome. DJ Tester, L. C.H. Wong, P Chanana, A Jaye, JM. Evans,DR FitzPatrick, MJ Evans, P Fleming, I Jeffrey, Marta C. Cohen, J Tfelt-Hansen, MA Simpson, ER Behr, MJ Ackerman. J Am Col Cardiol 2018; 71: 2017-2027
  6. Maternal use of methadone and risk of sudden neonatal death. M C Cohen, SJ Morley, RC Coombs. Acta Pediatrica. 2015; 104: 883–887
  7. How to optimise the yield of forensic and clinical post-mortem microbiology with an adequate sampling: a proposal for standardisation. Amparo Fernández-Rodríguez*, Marta C. Cohen*, Joaquin Lucena, Wim Van de Voorde, Annalisa Angelini, Nihan Ziyade, Veroniek Saegeman. European Journal of Clinical Microbiology & Infectious Diseases. (* both are 1st authors). 2015: 34(5): 1045-57
  8. Initial experiences of a minimally invasive autopsy service. A report of the techniques and observations in the first 11 cases. Whitby EH, Offiah AC, Cohen MC. Pediatric & Developmental Pathology. 18: 24-29, 2015
  9. Molecular abnormalities in pediatric Barrett’s esophagus: Can we test for potential of neoplastic progression? Maltby EL, Dyson MJ, Wheeler MR, Thomson M, Sethuraman C, Cohen MC. Pediatric Developmental Pathology 13: 310-317; 2010
  10. Diagnostic contribution of bacteriology and virology in Sudden Unexpected Death in Infancy. Pratk, Al-Adnani M, Fenton T, Koudesia G, Cohen M Archiv Dis Child May; 95(5):371-6. 2010.
  11. Less invasive autopsy: benefits and limitations of the use of magnetic resonance imaging in the perinatal post-mortem. M Cohen, M Paley, P Griffiths, E Whitby. Ped Develop Pathol. 11:1-9; 2008.