Professor John A Snowden BSc (Hons), MBChB, MD, FRCP, FRCPath

Consultant Haematologist, Director of Blood and Marrow Transplantation and Snowdenpic2
Honorary Professor of Haemato-oncology & Stem Cell Transplantation
Department of Haematology
Sheffield Teaching Hospitals NHS Foundation Trust

Tel: +44 (0) 114 271 3357 (Secretary)
Fax: +44 (0) 114 271 3862

Email: john.snowden@sth.nhs.uk

Biography

I graduated from the University of Leeds in 1989 and trained in Internal Medicine and Haematology in the UK, New Zealand and Australia. In 2002, I was appointed as Consultant Haematologist & Director of Blood and Marrow Transplantation (BMT) in the Sheffield Teaching Hospitals NHS Foundation Trust, and subsequently worked as Lead Clinician in Haemato-oncology for the Trust (2002-07) and Cancer Network (2007-10). My principal focus is the day-to-day provision and strategic development of tertiary level haematological cancer and BMT services (autologous, allogeneic and cord blood) for Sheffield and the North Trent Cancer Network region (covering a population of approximately 2 million). In 2012, Sheffield became the first Anthony Nolan collection centre outside London, thereby forming an important component of the Aligned UK Bone Marrow donor registry. In 2014, our services were recognised nationally in the Health Service Journal Awards as Cancer Care Team of the Year and I have been specially commended as an Anthony Nolan Clinical Supporter for 2014 and 2015.   In June 2016 I was appointed as Chair of the NHS England National Specialised Commissioning Clinical Reference Group (CRG) for BMT, overseeing current and future service provision of BMT across NHS England.

In conjunction with my NHS roles, and my Honorary Professor status with the Department of Oncology, I have contributed to research and educational activity in Haemato-oncology, Blood and Marrow Transplantation (BMT) and Stem Cell Biology. I have published over 200 clinical and scientific articles, reviews and book chapters, and led on key national and international clinical guidelines (Scopus h-index 35). I have organised a number of national and international conferences in BMT, Stem Cells and Late Effects in Cancer Survivors, both in Sheffield and elsewhere in Europe.

I am Chair of the EBMT Autoimmune Disease Working Party (www.ebmt.org) and Chair of the JACIE organisation (www.jacie.org), which oversees the accreditation of BMT programmes throughout Europe, having been Medical Director from 2012-2016. I am the current Secretary of the British Society for BMT (BSBMT). I am active in multicentre clinical trials and a member of the NCRI Haemato-oncology Clinical Studies Group (CSG). I have had key leadership roles in the areas of patient safety (NCEPOD SACT chemotherapy audit) and in NHS England National Specialised Commissioning (Clinical Reference Group for BMT). I was Lead Clinician for the updated NICE Improving Outcomes Guidance (IOG) in Haematological Cancers (www.nice.org.uk/guidance/ng47) and a guideline development group member of the NICE Guidelines for Multiple Myeloma (www.nice.org.uk/guidance/ng35).  I am the current Chair (until 2020) of the Intercollegiate Committee on Haematology (ICH) to the RCP and RCPath.

In January 2016, our work on stem cell transplantation in MS featured in a BBC Panorama documentary.

Academic Interests

  • Blood, marrow and umbilical cord derived haematopoietic stem cells in cancer and non-malignant disorders
  • Physical and psychological late effects in survivors of cancer treatment and BMT
  • Multiple myeloma, from cell biology to supportive care and survivorship research
  • Clinical and laboratory studies in leukaemia and other haematological cancers
  • Quality and health economics in haemato-oncology and BMT

Professional Activities

  • Chair (from 2015) & Medical Director (2012-16), JACIE Organisation; Co-Chair of FACT-JACIE Clinical Standards Sub-committee (2007-12) – producing 4th, 5th & 6th Editions of FACT-JACIE Standards, FACT HLA Typing Accreditation Committee Guidelines and Circular of Information for Cellular Therapy Products.
  • Chair of the EBMT Working Party for Autoimmune Diseases (from 2016), having been Secretary (2010-16).
  • NCRI Clinical Studies Group in Haematological Oncology:

       - Member by appointment from 2008
       - Chair of the Supportive Care, Transfusion & Late Effects Working Party (2015)

  • UK Myeloma Forum (UKMF) Executive by national election (2010-15, active in producing guidelines, educational activities and website).
  • British Society for Blood and Marrow Transplantation (BSBMT)

        - Member (2012-15) by national election
        - Secretary (2015) by national election

  • National and International Guidelines Work
  • National Institute for Health and Care Excellence (NICE)

       - Lead Clinician, NICE Improving Outcomes Guidance (IOG) in Haematological Cancers (2015-16)
         (www.nice.org.uk/guidance/ng47)
       - Guideline Development Group (GDG) member, NICE Guidelines for Multiple Myeloma (2014-16)
         (www.nice.org.uk/guidance/ng35)
        - Interventional procedure guidance (expert advisor), Autologous unmanipulated peripheral blood stem cell
          therapy for multiple sclerosis

  • British Committee for Standardisation in Haematology (BCSH)

       - BCSH/UK Myeloma Forum Guidelines Groups (Chair for Supportive Care and Late Effects Guidelines)
       - BCSH Aplastic Anaemia Guidelines Group

  • EBMT Guidelines in HSCT for Autoimmune Diseases (Lead Author)
  • Member of NCEPOD Working Group for Systemic Anti-Cancer Chemotherapy (SACT), leading to publication of report ‘Systemic Anti-Cancer Therapy: For better, for worse?’ in 2008
  • Peer reviewer for scientific journals including: The Lancet, BMJ, Bone Marrow Transplantation, British Journal of Haematology, International Journal of Laboratory Haematology, Leukemia Research, Hematology, Arthritis & Rheumatism, Journal of Rheumatology, Journal of Infection, Human Immunology, Clinical Rheumatology, British Journal of Anaesthesia, European Journal of Neurology, Cell Transplantation
  • Peer reviewer for grant awarding bodies including: Medical Research Council (MRC), Leukaemia & Lymphoma Research (LLR), Cancer Research UK (CRUK) European League against Rheumatism (EULAR), Arthritis Research Campaign (ARC), Raynaud’s and Scleroderma Society, and others
  • Peer reviewer for conference abstracts e.g. EBMT, ASH and national conferences
  • Editorial Board Member: International Journal of Laboratory Haematology, Wiley-Blackwell (2006-) and Current Research in Translational Medicine, Elselvier (2012-)
  • Clinical Co-investigator for NCRI portfolio multicentre trials; Myeloma X, TRYMS, UKALL60+, Myeloma XII
  • DMEC and Trial Steering Group Work
  • UKNEQAS Leucocyte Immunophenotyping Steering Group (2014-)
  • Chair, Intercollegiate Committee on Haematology (ICH) to the RCP and RCPath

Contributions to National & International Educational Meetings

Recent Examples of Invited Lecturer, Chairing and Organising Committees

2017

  • Invited speaker and session chair, Tandem Meeting of the American Society for Blood and Marrow Transplantation (ASBMT) and Centre for International Bone Marrow Transplant Research (CIBMTR), Orlando, FL, USA, February 2017
  • Organiser, Invited Speaker, Abstract Reviewer, Sessional Chair, Annual EBMT Meeting, Marseille, March 2017
  • Organiser, Invited Speaker, NCRI Haemato-oncology Annual Trials Day, May 2017
  • Invited Speaker, 'Inflammation, breaking down Silos', Oxford University, June 2017
  • Invited Speaker, University of Jordan, October 2017
  • Organiser, Invited Speaker, BSBMT Annual Educational Meeting, London, November 2017
  • Organiser, Invited Speaker, EBMT 'Educational Meeting of Autoimmune Diseases and Inborn Errors Working Parties', Newcastle, November 2017

2016

  • Organiser, Invited speaker, Educational Meeting of Autoimmune Diseases Working Party, Berlin, January 2016
  • Invited speaker, Autoimmune Diseases Meeting, Porto, Portugal, January 2016
  • Invited speaker, Sessional Chair, Annual EBMT Meeting, Valencia, April 2016 (4 invited lectures)
  • Invited speaker, XXXVI World Congress of the International Society of Haematology hosted by the British Society for Haematology, Glasgow, April 2016 (2 invited lectures)
  • Invited speaker, EBMT Highlights, Saudi Society for BMT, Jeddah, May 2016
  • Invited speaker, University of Oxford Neurology Course, June 2016
  • Invited speaker, Myeloma UK Roadshow, Birmingham, September 2016
  • Organiser, invited speaker and Chair, International Meeting on Stem Cell Transplantation in MS, Sheffield, October 2016
  • Organiser, invited speaker and Chair, Annual Educational Meeting of the British Society for Blood and Marrow Transplantation (BSBMT), London November 2016
  • Organiser, invited Chair, Joint Educational Meeting of the Autoimmune Diseases Working Party (ADWP) and Severe Aplastic Anaemia Working Party (SAAWP), Paris, November 2016
  • Invited Speaker, MS Trust Annual Conference, London, November 2016
  • Organiser, invited speaker and Chair, The Late Medical Effects of Cancer treatments, Royal College of Physicians of London, November 2016
  • Invited speaker, Autoimmunity and Immunodeficiency Diseases Conference, Moscow, Russia, December 2016

2015

  • Invited Speaker, Abstract Reviewer, Sessional Chair, Annual EBMT Meeting, Istanbul
  • Invited Speaker, Northwestern University, Chicago
  • Invited Chair, UK NEQAS Immunophenotyping Annual Conference, Sheffield

2014

  • Invited Speaker, ASBMT Tandem Meeting, Texas
  • Invited Speaker, Abstract Reviewer, Sessional Chair, Annual EBMT Meeting, Milan
  • Organiser, Invited speaker, Abstract Reviewer, ‘Late Effects in Cancer Survivors’ (5th Biennial Meeting), Sheffield, UK
  • Invited Speaker, Nanjing University, China

2013

  • Invited Speaker, Nanjing University Stem Cell Transplant Symposium, China
  • Invited Speaker, Abstract Reviewer, Sessional Chair, Annual EBMT Meeting, London
  • Invited Speaker, BSBMT Spring Educational Meeting, London
  • Invited Speaker, Pretoria East Hospital, South Africa
  • Organiser, Invited speaker, ‘Educational Meeting of Autoimmune Diseases Working Party’, Sheffield, November

2012

  • Organiser, Invited speaker, Abstract Reviewer, ‘Late Effects in Cancer Survivors’ (4rd Biennial Meeting), Sheffield
  • Invited speaker, Association of Clinical Pathologists Annual Meeting, London
  • Invited Speaker, Stem Cell Therapy in Autoimmune Diseases Symposium, Northwestern University, Chicago
  • Organiser, Invited speaker, ‘Educational Meeting of Immune Biology and Autoimmune Diseases Working Parties’, Paris

2011

  • Invited Speaker, American Society for Blood and Marrow Transplantation, Honolulu
  • Invited Speaker, Stem Cell Therapy in Autoimmune Diseases Symposium, Northwestern University, Chicago
  • Invited Speaker, Abstract Reviewer, Sessional Chair, Annual EBMT Meeting, Paris
  • Organiser, Invited speaker, ‘Educational Meeting of Severe Aplastic Anaemia, Late Effects and Autoimmune Diseases Working Parties’, Barcelona

Publications

Please see the link to the right.


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