Dr Nasreen Akhtar

Akhtar N, Weiping Li, Mironov A and Streuli CH. (2016) ‘Rac1 controls both the secretory function of the mammary gland and its remodeling for successive gestations’. Developmental Cell, 38, 1-14. (Corresponding author).

Akhtar N and Streuli CH. (2013) ‘An integrin-ILK-microtubule dependent network orients polarity and lumen formation in glandular epithelium’. Nature Cell Biol, 15(1) pp 17-27. (Co-corresponding author).

Jeanes AI, Wang P, Moreno-Layseca P, Paul N, Cheung J, Tsang R, Akhtar N, et al., (2012). ‘Specific-containing integrins exert differential control on proliferation and two-dimensional collective cell migration in mammary epithelial cells’. J Biol Chem, 287(29), pp24103-12.

Akhtar N, Marlow R, Lambert E, Schatzmann F, Lowe ET, Cheung J, Katz E, Li W, Wu C, Dedhar S, Naylor MJ, Streuli CH. (2009) ‘Molecular dissection of integrin signalling proteins in the control of mammary epithelial development and differentiation.’ Development, 136 (6) 1019.

Streuli CH and Akhtar N. (2009) ‘Signal co-operation between integrins and other receptor systems’. Biochem J, 418 (3) 491. Review

Akhtar N. and Streuli CH. (2006) ‘Rac1 links integrin-mediated adhesion to the control of lactational differentiation in epithelia’ J Cell Biol, 173 (5) 781-93.

Zoubiane GS, Valentijn A, Lowe ET, Akhtar N, Bagley S, Gilmore AP, Streuli CH. (2004) ‘A role for the Cytoskeleton in prolactin-dependent mammary epithelial cell differentiation’ J Cell Science, 117 (pt2), pp271-80.

Akhtar N and Hotchin NA. (2001), ‘Rac regulates adherens junctions through endocytosis of E-cadherin’ Mol. Biol. Cell. 12, pp847-862.

Woodfield RJ, Hodgkin MN, Akhtar N, Morse MA, Fuller KJ, Saqib K, Thompson NT and Wakelam MJ (2001). ‘The p85 subunit of phosphoinositide 3-kinase is associated with beta catenin in the cadherin based adhesion complex’ Biochem J, 360 (pt2), pp335-344.

Knight B., Laukaitsis C., Akhtar N., Hotchin NA., Edlind M. and Horwitz AR. (2000). ‘Visualising cell migration in situ.’ Curr. Biol. 10, pp576-585.

Hotchin NA., Cover TL and Akhtar N. (2000). ‘Cell vacuolation induced by the VacA cytotoxin of Helicobacter pylori is regulated by the Rac1 GTPase’. J. Biol. Chem. 275, pp14009-14012.

Akhtar N., Hudson KR. and Hotchin NA. (2000) ‘Co-localisation of Rac1 and E-Cadherin in human epidermal keratinocytes’ Cell Adhes.Comm. 7, pp465-476.

Akhtar N., Linstead D. and Wakelam MJ. (1996) ‘EGF-regulated signal transduction in hormone dependent and hormone independent breast cancer’ Biochemical Society Transactions, 658th meeting, Liverpool.

Journal articles