@article{article, title = {{Negative DNA supercoiling induces genome-wide Cas9 off-target activity}}, publisher = {{Elsevier BV}}, url = {{https://eprints.whiterose.ac.uk/id/eprint/232907 https://doi.org/10.1016/j.molcel.2023.09.008 }}, year = {{2023}}, month = {{10}}, author = {{Newton MD and Losito M and Smith QM and Parnandi N and Taylor BJ and Akcakaya P and Maresca M and van Eijk P and Reed SH and Boulton SJ and King GA et al}}, doi = {{10.1016/j.molcel.2023.09.008}}, volume = {{83}}, journal = {{Molecular Cell}}, issue = {{19}}, pages = {{3533-3545.e5}}, note = {{Accessed on 2025/10/29}}}