@article{article, title = {{A65-11 Study Design of a Phase 2a Randomized, Placebo-controlled Trial of Inhaled Frespaciguat (MK-5475) in Adults with Pulmonary Hypertension Associated with Chronic Obstructive Pulmonary Disease (INSIGNIA PH-COPD)}}, publisher = {{Oxford University Press (OUP)}}, url = {{https://doi.org/10.1093/ajrccm/aamag162.5573 }}, year = {{2026}}, month = {{5}}, author = {{Kiely DG and Waxman AB and Criner GJ and Chin KM and Humbert MJ and Fu W and Ford M and Kovacs G}}, doi = {{10.1093/ajrccm/aamag162.5573}}, volume = {{212}}, journal = {{American Journal of Respiratory and Critical Care Medicine}}, issue = {{Supplement_1}}, note = {{Accessed on 2026/08/14}}}