@article{article, title = {{Matrix-directed therapy losartan to identify the effect on the bone resorption marker carboxy-terminal crosslink of type I collagen telopeptide (CTX) in older adolescents and adults with osteogenesis imperfecta recruited from secondary care sites: the ‘MOI-A’ study; a randomised, phase 2/pilot, dose-escalating trial}}, publisher = {{BMJ}}, url = {{https://doi.org/10.1136/bmjopen-2025-107243 }}, year = {{2025}}, month = {{12}}, author = {{Haji Sadeghi M and Cohen J and Williams B and Wilkinson A and Sumpter S and Simms L and Huang C and Pugh K and Heath C and Sangiorgi L and Gurioli F et al}}, doi = {{10.1136/bmjopen-2025-107243}}, volume = {{15}}, journal = {{BMJ Open}}, issue = {{12}}, pages = {{e107243-e107243}}, note = {{Accessed on 2026/02/05}}}