@article{article, title = {{Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity}}, publisher = {{Springer Science and Business Media LLC}}, url = {{https://doi.org/10.1038/s41586-026-10255-7 }}, year = {{2026}}, month = {{3}}, author = {{Smith QM and Whittle S and Aramayo RJ and Rollins DE and Jalal ASB and Egharevba DI and Morris KL and Pyne ALB and Rueda DS}}, doi = {{10.1038/s41586-026-10255-7}}, journal = {{Nature}}, note = {{Accessed on 2026/03/28}}}