TY - JOUR T1 - An enzyme with high catalytic proficiency utilizes distal site substrate binding energy to stabilize the closed state but at the expense of substrate inhibition JO - ACS Catalysis UR - https://eprints.whiterose.ac.uk/id/eprint/183780 PY - 2022/02/22 AU - Robertson A AU - Cruz-Navarrete FA AU - Wood H AU - Vekaria N AU - Hounslow A AU - Bisson C AU - Cliff M AU - Baxter N AU - Waltho J ED - DO - DOI: 10.1021/acscatal.1c05524 PB - American Chemical Society VL - 12 IS - 5 SP - 3149 EP - 3164 Y2 - 2025/11/13 ER -