BSc (Hons), DPhil
School of Health and Related Research
NIHR Research Design Service Yorkshire and the Humber
+44 114 222 4384
Full contact details
School of Health and Related Research
Regent Court (ScHARR)
30 Regent Street
I joined the university in 2009 as part of the Late Effects Research Team in the Academic Unit of Clinical Oncology. As part of this team, I was project manager for a feasibility study investigating models of follow-up care in cancer survivors. I am a co-investigator on a study looking at return to work in cancer survivors and a pilot study, Fitness To Treat: effectiveness of a clinical assessment for older men with cancer (FiTT).
I joined ScHARR as a Research Fellow in May 2013 and my current position is Manager for the Sheffield spoke of the NIHR Research Design Service Yorkshire and Humber (RDS YH). As an RDS advisor, I offer generalist advice and support to researchers to develop and design high quality research proposals for submission to the NIHR and other national, peer-reviewed funding competitions for applied health or social care research.
My previous role was a post-doctoral researcher at The Wellcome Trust Centre for Human Genetics, University of Oxford investigating the genetics of diet-induced insulin resistance. Previous research has included working on the Biological Atlas of Insulin Resistance (BAIR), an International Consortium set up to characterise the molecular basis of insulin action and insulin resistance.
• FiTT: Fitness to treat in older men with cancer
• ATWORK: Return to work in cancer survivors
- Research interests
My research interests are investigating the long-term consequences of cancer treatment.
This person does not have any publications available.
- Systems Genetics of Hepatic Metabolome Reveals Octopamine as a Target for Non-Alcoholic Fatty Liver Disease Treatment. Scientific Reports, 9. View this article in WRRO
- Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance. Cell Reports, 20(1), 136-148. View this article in WRRO
- P145 La trimethylamine, métabolite du microbiote intestinal, inhibe la voie inflammatoire des Toll-Like Receptor (TLRs) via une inhibition directe d’une enzyme clé de la transduction du signal. Diabetes & Metabolism, 41, A69-A69.
- Nutrigenomics of high fat diet induced obesity in mice suggests relationships between susceptibility to fatty liver disease and the proteasome.. PLoS One, 8(12), e82825.
- Expression of microRNAs in response to high fat diet. DIABETES METAB, 37, A30-A31.
- Broad-ranging natural metabotype variation drives physiological plasticity in healthy control inbred rat strains.. J Proteome Res, 10(4), 1675-1689.
- Progression of diet-induced diabetes in C57BL6J mice involves functional dissociation of Ca2(+) channels from secretory vesicles.. Diabetes, 59(5), 1192-1201.
- Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice. PLoS ONE, 3(2).
- Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models. Nature Genetics, 39(5), 666-672.
- Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice. Diabetologia, 50(9), 1867-1879.
- Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice.. Proc Natl Acad Sci U S A, 103(33), 12511-12516.
Conference proceedings papers
- Altered microRNAs expression is associated with insulin resistance status in high fat diet fed mice. DIABETOLOGIA, Vol. 53 (pp S31-S32)
- Attenuation of Ca2+ microdomains and diet-induced diabetes in mice. DIABETOLOGIA, Vol. 52 (pp S163-S163)
- Identification and characterisation of candidate genes in diet-induced non-alcoholic fatty liver disease in inbred mice. DIABETOLOGIA, Vol. 52 (pp S259-S259)
- IDENTIFICATION OF CANDIDATE GENES IN DIET INDUCED NON-ALCOHOLIC FATTY LIVER DISEASE IN INBRED MICE. JOURNAL OF HEPATOLOGY, Vol. 50 (pp S258-S258)
- Correction to: Comprehensive geriatric assessment and decision-making in older men with incurable but manageable (chronic) cancer. Supportive Care in Cancer, 29(2), 1145-1145.
- Teaching interests
I teach on the Research Methodology course for the Yorkshire and Humber Deanery and supervise masters and medical students.