Dr John W Stevens

PhD, BSc (Hons)

School of Health and Related Research

Reader in Decision Science

j.w.stevens@sheffield.ac.uk
+44 114 222 6396

Full contact details

Dr John W Stevens
School of Health and Related Research
1017
Regent Court (ScHARR)
30 Regent Street
Sheffield
S1 4DA
Profile

My primary role is Director of the Centre for Bayesian Statistics in Health Economics (CHEBS). I graduated from Brunel University in 1982 with a BSc in Statistics/Mathematics. After graduating, I worked in the pharmaceutical industry for 24 years, including at SK&F Research Ltd (1982 – 1986), Wellcome Research Laboratories (1986 – 1995), GlaxoWellcome (1995 – 1996) and AstraZeneca R&D Charnwood (1996 – 2006). During this time I gained experience in the design and analysis of pre-clinical studies and in all phases of clinical drug development, and held a variety of management positions.

In 1998, I assumed a technical role in the development and application of statistical methods to improve the drug development process, with a particular interest in Bayesian methods. During this time, I became interested in the application of Bayesian methods in health economics and was actively involved in the creation of CHEBS. My PhD was on latent variable modelling of effectiveness and resource use data in cost-effectiveness analyses of clinical trials. I moved to the University of Sheffield in November 2006 to provide leadership to CHEBS and further develop my Bayesian interests.

Research interests
  • the application of Bayesian methods in drug development
  • statistical methods in health economics
  • evidence synthesis
  • sample size determination under uncertainty
  • adaptive dose finding

Current projects

I am currently working on the following projects:

  • An evidence synthesis, meta-analysis and decision analytic modelling following a systematic review of quantitative and qualitative studies evaluating the effectiveness, cost-effectiveness, safety and acceptability of interventions to prevent post-natal depression (PND). National Institute for Health Research: Health Technology Assessment Programme. 1 November 2012 – 31 January 2013. Co-investigator (£178,135)
  • Bridging the age gap in breast cancer. Improving outcomes for older women. National Institute for Health Research. 1 June 2012 – 31 May 2017. Co-investigator (£590,105)
  • Methods of extrapolating RCT evidence for economic evaluation. Medical Research Council: 1 October 2010 – 31 March 2012. Co-investigator (£313,888).
Publications

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Journal articles

All publications

Journal articles

Conference proceedings papers

Posters

  • Bhrmal M, Kapetanakis V, Schlichting M, Stevens JW, Kearnmey M, Phatak H & Benedict A (2018) How to correct for differences in study design when making indirect comparisons using evidence from single-arm studies in immune-oncology.. Academy of Managed Care Pharmacy NEXUS 2018. RIS download Bibtex download
  • Ghabri S, Simpson EL, Ren S, Hock E, Archer R, Binard A, Pers Y, Stevens JW, Herpin C & Stevenson M (2018) PMS4 - RHEUMATOID ARTHRITIS TREATED WITH SIX-MONTHS OF FIRST-LINE BIOLOGIC OR BIOSIMILAR THERAPY: A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS. RIS download Bibtex download
  • Archer R, Clowes M, Hamilton J, Pandor A, Stevenson MD, Stevens JW, Hock ES & Essat M (2018) Addressing challenges in the conduct of a systematic review of clinical prediction models in rheumatoid arthritis. 25th Cochrane Colloquium, Edingurgh. RIS download Bibtex download
  • Hamilton J, Archer R, Stevens J, Stevenson M, Hock E, Clowes M, Essat M, Poku E & Pandor A (2018) Clinical prediction models for patients with early rheumatoid arthritis: A systematic review and evidence synthesis. MEMTAM (Methods for Evaluation of medical prediction Models, Test And Biomarkers), Utecht, The Nethe. RIS download Bibtex download
  • Ren S, Oakley J & Stevens JW (2018) Evidence synthesis with limited studies. HTAi 2018, Vancouver, Canada. RIS download Bibtex download
  • Ren S, Oakley J & Stevens JW (2017) Evidence synthesis for health technology assessment with limited studies.. . ISPOR Glasgow 2017. RIS download Bibtex download
  • Ren S, Oakley JE & Stevens JW (2017) EVidence Synthesis For Health Technology Assessment With Limited Studies. RIS download Bibtex download
  • Stevens JW, Harvey RC, Johnson M & Khunti K (2014) Preventing the Progression to Type 2 Diabetes Mellitus in Adults at High Risk: A Systematic Review And Network Meta-Analysis of Lifestyle, Pharmacological and Surgical Interventions. RIS download Bibtex download
  • Goodacre S (2014) PRE-HOSPITAL NON-INVASIVE VENTILATION FOR ACUTE RESPIRATORY FAILURE: A SYSTEMATIC REVIEW AND NETWORK META ANALYSIS. RIS download Bibtex download
  • Goodacre S, Pandor A, Poku E, Stevens JW, Ren S & Cantrell A Pre-hospital non-invasive ventilation for acute respiratory failure: a systematic review and network meta-analysis. 999 EMS Research Forum Conference. RIS download Bibtex download
Teaching interests
  • HAR670: Medical Statistics and Evidence Synthesis
  • HAR6035: An Introduction to Medical Statistics and Critical Appraisal
  • PAS6062: Further Clinical Trials
Professional activities

In addition to my role as Director of CHEBS, I am:

  • a member of the National Institute for Health and Clinical Excellence (NICE) Appraisal Committee
  • on the panel of expert reviewers for the National Institute for Health Research (NIHR) Health Technology Programme
  • Editor-in-Chief of the Pharmaceutical Statistics journal