Key Publications by CTRU Staff

Prof. Cindy Cooper

  • McDermott, C. J., Shaw, P. J., Cooper, C. L., Dixon, S., Baird, W. O., Bradburn, M. J., Radunovic, A. (2015). Safety and efficacy of diaphragm pacing in patients with respiratory insufficiency due to amyotrophic lateral sclerosis (DiPALS): A multicentre, open-label, randomised controlled trial. The Lancet Neurology, 14(9), 883-892. doi:10.1016/S1474-4422(15)00152-0
  • Cooper, C. L., Hind, D., Duncan, R., Walters, S., Lartey, A., Lee, E., & Bradburn, M. (2015). A rapid review indicated higher recruitment rates in treatment trials than in prevention trials. Journal of Clinical Epidemiology, 68(3), 347-354. doi:10.1016/j.jclinepi.2014.10.007
  • Cooper, C., O'Cathain, A., Hind, D., Adamson, J., Lawton, J., & Baird, W. (2014). Conducting qualitative research within Clinical Trials Units: avoiding potential pitfalls.. Contemp Clin Trials, 38(2), 338-343. doi:10.1016/j.cct.2014.06.002
  • Cooper, C. L., Hind, D., Parry, G. D., Isaac, C. L., Dimairo, M., O'Cathain, A., Sharrack, B. (2011). Computerised cognitive behavioural therapy for the treatment of depression in people with multiple sclerosis: external pilot trial. Trials, 12, 259. doi:10.1186/1745-6215-12-259
  • Arain, M., Campbell, M. J., Cooper, C. L., & Lancaster, G. A. (2010). What is a pilot or feasibility study? A review of current practice and editorial policy.. BMC Med Res Methodol, 10, 67. doi:10.1186/1471-2288-10-67
  • What does it mean to involve consumers successfully in NHS research? A consensus study.. Health Expect, 7(3), 209-220. doi:10.1111/j.1369-7625.2004.00278.x

Jessica Wright

  • Wallace S, Laurie G, Gourna E, Shoush O & Wright J (2015) Respecting autonomy over time: policy and empirical evidence on re-consent in longitudinal biomedical research. Bioethics.
  • Bijlenga P, Ebeling C, Jaegersberg M, Summers P, Rogers A, Waterworth A, Iavindrasana J, Macho J, Pereira VM, Bukovics P, Vivas E, Sturkenboom MCJM, Wright J, Friedrich CM, Frangi A, Byrne J, Byrne J, Schaller K & Rufenacht D (2013) Risk of rupture of small anterior communicating artery aneurysms is similar to posterior circulation aneurysms. Stroke, 44(11), 3018-3026.
  • Wright J, Ploem C, Śliwka M & Gevers S (2010) Regulating Tissue Research: Do we need additional rules to protect research participants?. European Journal of Health Law, 17, 455-469.

Liz Cross

  • Goodacre SW, Bradburn M, Cross E, Collinson P, Gray A, Hall AS on behalf of the RATPAC Research Team. The Randomised Assessment of Treatment using Panel Assay of Cardiac Markers (RATPAC) trial: a randomised controlled trial of point-of-care cardiac markers in the emergency department. Heart 2011 97(3):190-196 originally published online September 30, 2010. Doi: 10.1136/hrt.2010.203166
  • Cross E, Goodacre S. Patient satisfaction with chest pain unit care: findings from the Effectiveness and Safety of Chest Pain Assessment to Prevent Emergency Admissions (ESCAPE) cluster randomised trial. EMJ 2010;27:774-778 Published Online First: 20 July 2010 doi:10.1136/emj.2009.086298
  • Mark L Everard, Daniel Hind, Kelechi Ugonna, Jennifer Freeman, Mike Bradburn, Cindy L Cooper, Elizabeth Cross, Chin Maguire, Hannah Cantrill, John Alexander, Paul S McNamara, on behalf of The SABRE Study Team. SABRE: a multicentre randomised control trial of nebulised hypertonic saline in infants hospitalised with acute bronchiolitis. Thorax 2014;69:1105-1112 doi:10.1136/thoraxjnl-2014-205953

Rebecca Gossage-Worrall

Chin Maguire

  • Everard ML, Hind D, Ugonna K, Freeman J, Bradburn M, Cooper CL, Cross E, Maguire C, Cantrill H, Alexander J, McNamara PS. SABRE: a multicentre randomised controlled trial of nebulised hypertonic saline in infants hospitalised with acute bronchiolitis. Thorax, 2014; 69:12
  • Maguire C, McDermott CJ, Hind D, Radunovic A, Shaw PJ. Diaphragm pacing systems for amyotrophic lateral sclerosis/ motor neuron disease. Cochrane Database of Systematic Reviews 2014, Issue 11. Art. No.: CD011222. DOI: 10.1002/14651858.CD011222
  • Safety and efficacy of diaphragm pacing in patients with respiratory insufficiency due to amyotrophic lateral sclerosis (DiPALS): a multicentre, open-label, randomised controlled trial. Lancet Neurology. www.thelancet.com/neurology Published online July 31, 2015 http://dx.doi.org/10.1016/S1474-4422(15)00152-0

David White

  • Lawton J, Kirkham J, White D, Rankin D, Cooper C & Heller S (2015) Uncovering the emotional aspects of working on a clinical trial: A qualitative study of the experiences and views of staff involved in a type 1 diabetes trial. Trials, 16(1).
  • White D & Hind D (2015) Projection of participant recruitment to primary care research: a qualitative study. Trials, 16(1).
  • Gilbody S, Littlewood E, Hewitt C, Brierley G, Tharmanathan P, Araya R, Barkham M, Bower P, Cooper C, Gask L, Kessler D, Lester H, Lovell K, Parry G, Richards DA, Andersen P, Brabyn S, Knowles S, Shepherd C, Tallon D & White D () Computerised cognitive behaviour therapy (cCBT) as treatment for depression in primary care (REEACT trial): large scale pragmatic randomised controlled trial. BMJ, h5627-h5627.

Prof Steven Julious

  • Whitehead AL, Julious SA, Cooper CL and Campbell MJ. Estimating the sample size for a pilot randomised trial to minimise the overall trial sample size for the external pilot and main trial for a continuous outcome variable.Statistical Methods in Medical Research 2015 DOI: 10.1177/0962280215588241
  • Glasziou P, Altman DG Bossuyt P, Boutron I, Clarke M, Julious S, Michie S, Moher D and Wager E. Reducing waste from incomplete or unusable reports of biomedical research.The Lancet 2014 383(9913): 267-276
  • Horspool MJ, Julious SA, Boote J, Bradburn MJ, Cooper CL, Davis S, Elphick H, Norman P, Smithson WH and van Staa T. Preventing and lessening exacerbations of asthma in school-age children associated with a new term (PLEASANT): study protocol for a cluster randomised control trial. Trials 2013, 14:297 doi:10.1186/1745-6215-14-297

Prof Michael Campbell

  • Campbell MJ and Walters SJ (2014) How to design, analyse and report cluster randomised trials in medicine and health related research. Wiley-Blackwell 247pp ISBN 978-1-119-99202-8
  • Campbell MJ, Jacques RM, Fotheringham J, Maheswaran R, Nicholl J (2012) Developing a summary hospital mortality index: retrospective analysis in English hospitals over five years. BMJ doi=10.1136/bmj.e1001
  • Latimer NR, Abrams KR, Lambert PC, Crowther MJ, Wailoo AJ, Morden JP, Akehurst RL, Campbell MJ (2014). Adjusting for treatment switching in randomised controlled trials – a simulation study and a simplified two-stage method. Statistical Methods in Medical Research. DOI: 10.1177/0962280214557578

Mike Bradburn

  • (2015) Safety and efficacy of diaphragm pacing in patients with respiratory insufficiency due to amyotrophic lateral sclerosis (DiPALS): a multicentre, open-label, randomised controlled trial. The Lancet Neurology, 14(9), 883-892.
  • Everard ML, Hind D, Ugonna K, Freeman J, Bradburn M, Cooper CL, Cross E, Maguire C, Cantrill H, Alexander J & McNamara PS (2014) SABRE: a multicentre randomised control trial of nebulised hypertonic saline in infants hospitalised with acute bronchiolitis. Thorax, 69(12), 1105-1112.
  • Goodacre SW, Bradburn M, Cross E, Collinson P, Gray A & Hall AS (2010) The Randomised Assessment of Treatment using Panel Assay of Cardiac Markers (RATPAC) trial: A randomised controlled trial of point-of-care cardiac markers in the emergency department. Heart, 97(3), 190-196.

Neil Shephard

  • Teare, M., Dimairo, M., Shephard, N., Hayman, A., Whitehead, A., and Walters, S. (2014). Sample size requirements to estimate key design parameters from external pilot randomised controlled trials: a simulation study. Trials 15, 264+
  • Glossop, A. J., Shephard, N., Bryden, D. C., and Mills, G. H. (2012). Non-invasive ventilation for weaning, avoiding reintubation after extubation and in the postoperative period: a meta-analysis. British Journal of Anaesthesia 109, 305–314.
  • Goodacre, S., Wilson, R., Shephard, N., Nicholl, J., and DAVROS Research Team. (2012). Derivation and validation of a risk adjustment model for predicting seven day mortality in emergency medical admissions: mixed prospective and retrospective cohort study. BMJ (Clinical research ed.) 344.

Munya Dimairo

  • Teare MD, Dimairo M, Shephard N, Hayman A, Whitehead A, Walters SJ. Sample size requirements to estimate key design parameters from external pilot randomised controlled trials: a simulation study. Trials. 2014 Jul 3;15:264. doi: 10.1186/1745-6215-15-264. PubMed PMID: 24993581; PubMed Central PMCID: PMC4
  • Dimairo M, Boote J, Julious SA, Nicholl JP, Todd S. Missing steps in a staircase: a qualitative study of the perspectives of key stakeholders on the use of adaptive designs in confirmatory trials. Trials. 2015 Sep 28;16(1):430. doi: 10.1186/s13063-015-0958-9. PubMed PMID: 26416387.227298.
  • Goyder E, Hind D, Breckon J, Dimairo M, Minton J, Everson-Hock E, Read S, Copeland R, Crank H, Horspool K, Humphreys L, Hutchison A, Kesterton S, Latimer N, Scott E, Swaile P, Walters SJ, Wood R, Collins K, Cooper C. A randomised controlled trial and cost-effectiveness evaluation of 'booster' interventions to sustain increases in physical activity in middle-aged adults in deprived urban neighbourhoods. Health Technol Assess. 2014 Feb;18(13):1-210. doi: 10.3310/hta18130. PubMed PMID: 24571932.

Dan Beever

Hannah Cantrill

  • Everard ML, Hind D, Ugonna K, Freeman J, Bradburn M, Cooper CL, Cross E, Maguire C, Cantrill H, Alexander J, McNamara PS, Dixon S, Lenney W, Elphick H, Chetcuti PA, Moya EF, Powell C, Garside JP, Chadha L, Kurian M, Lehal RS, MacFarlane PI. SABRE: a multicentre randomised control trial of nebulised hypertonic saline in infants hospitalised with acute bronchiolitis. Thorax. 2014 Nov 11;69(12):1105–12.

Amanda Loban

  • Green, M. et al. 2014. 'Fish out of water': A cross-sectional study on the interaction between social and neighbourhood effects on weight management behaviours. International journal of obesity 39, 535-541
  • Green, M. et al. 2014. Cohort Profile: The Yorkshire Health Study. International Journal of Epidemiology 07/2014; DOI: 10.1093/ije/dyu121
  • Relton, C. et al., 2011. South Yorkshire Cohort: a 'cohort trials facility' study of health and weight - protocol for the recruitment phase. BMC Public Health, 11:640.

Tim Chater

  • Sprange K, Mountain GA, Brazier J, Cook SP, Craig C, Hind D, Walters SJ, Windle G, Woods R, Keetharuth AD, Chater T & Horner K (2013) Lifestyle Matters for maintenance of health and wellbeing in people aged 65 years and over: study protocol for a randomised controlled trial.. Trials, 14, 302.
  • Parslow RC, Tasker RC, Draper ES, Parry GJ, Jones S, Chater T, Thiru K, McKinney PA & Paediatric Intensive Care Audit Ne (2009) Epidemiology of critically ill children in England and Wales: incidence, mortality, deprivation and ethnicity. ARCH DIS CHILD, 94(3), 210-215.
  • Pickin M, Cooper CL, Chater T, O'Hagan A, Abrams KR, Cooper NJ, Boggild M, Palace J, Ebers G, Chilcott JB, Tappenden P & Nicholl J (2009) The Multiple Sclerosis Risk Sharing Scheme Monitoring Study--early results and lessons for the future.. BMC Neurol, 9, 1.

Diana Papaioannou

  • Papaioannou D, Brazier J & Parry G (2013) How to measure quality of life for cost-effectiveness analyses of personality disorders: a systematic review.. J Pers Disord, 27(3), 383-401
  • Papaioannou D, Rafia R, Rathbone J, Stevenson M, Buckley Woods H & Stevens J (2012) Rituximab for the first-line treatment of stage III-IV follicular lymphoma (review of Technology Appraisal No. 110): a systematic review and economic evaluation..Health Technol Assess, 16(37), 1-iv.
  • Papaioannou D, Brazier J & Parry G (2011) How valid and responsive are generic health status measures, such as EQ-5D and SF-36, in schizophrenia? A systematic review.. Value Health, 14(6), 907-92