Photograph of Katie BiggsKatie Biggs, MA (Hons) University of Edinburgh, MSc University of Liverpool

Lead Trial Manager

Clinical Trials Research Unit, ScHARR
The University of Sheffield
Regent Court, 30 Regent Street
S1 4DA

Room: 2028, Regent Court
Tel: +44 (0)114 22 26128
Fax: +44 (0)114 222 0870

email :



I am the Lead Trial Manager in the CTRU. I manage multi-centre trials and contribute to proposal development within the CTRU.

I am managing the HubBLe trial, a surgical RCT and the PRACTICE trial, a pilot RCT of pulmonary rehabilitation in COPD. I am a co-applicant, and senior oversight, on the ASPECT trial, an RCT of Cognitive Behavioural Therapy (CBT) vs One Session Treatment (OST) for simple phobias. All of these projects are funded by the HTA.

I joined the Clinical Trials Research Unit in March 2010 having previously worked in various mental health services as a support worker. My previous roles included psychometric testing and data collection from service users and families. My psychology based degrees provided good grounding in research methods, data collection and analysis.

In CTRU I have previously worked on 3Mg (HTA – 06/01/02), Well-being and ADHD (funded by Shire) and MERIDIAN (HTA – 09/06/01).

Teaching Interests

I am involved in delivering various aspects of Master level programs at ScHARR including:

  • Supervising and marking dissertations on the Masters in Public Health, Masters in Health Services Research and Masters in Clinical Research
  • Co-ordination and marking of the iHTA online module HAR6116: Randomised Controlled Trials to Support Reimbursement Decision Making
  • Personal tutor to Masters Level students.

Current and Recent Projects

  • The HubBLe trial (HTA – 10/57/46)
  • The PRACTICE trial (HTA – 13/24/03)
  • The ASPECT trial (HTA – 15/38/04).

Professional Activities

I am the section representative on the ScHARR Impact Strategy Group and I sit on the ScHARR Research Ethics Committee.


Please click here for a full list of Katie's publications.

  • Campbell F, Biggs K, Aldiss SK, O'Neill PM, Clowes M, McDonagh J, While A, Gibson F. Transition of care for adolescents from paediatric services to adult health services. Cochrane Database of Systematic Reviews. 2016, Issue 4. Art. No.: CD009794. DOI: 10.1002/14651858.CD009794.pub2
  • Brown SR, Tiernan JP, Watson AJ, Biggs K, Shephard N, Wailoo AJ, Bradburn M, Alshreef A, Hind D and HubBLe Study team. Haemorrhoidal artery ligation versus rubber band ligation for the management of symptomatic second-degree and third-degree haemorrhoids (HubBLe): a multicentre, open-label, randomised controlled trial. The Lancet. 2016 388:356-364. DOI:
  • Peasgood T, Bhardwaj A, Biggs K, Brazier JE, Coghill D, Cooper CL, Daley D, Silva C, Harpin V, Hodgkins P, Nadkarni A. The impact of ADHD on the health and well-being of ADHD children and their siblings. European Child & Adolescent Psychiatry. 2016 Apr 1:1-5.
  • Biggs K and Cooper CL. Use of home visits increases data completion and retention in studies involving family members. Trials 2015 16(Suppl 2):O24. DOI:10.1186/1745-6215-16-S2-O24
  • Tiernan J, Hind D, Watson A, Wailoo AJ, Bradburn M, Shephard N, Biggs K and Brown S Study Protocol. The HubBLe Trial: haemorrhoidal artery ligation (HAL) versus rubber band ligation (RBL) for heamorrhoids. BMC Gastroenterology. 2012, 12:153. DOI: 10.1186/1471-230X-12-153
  • Goodacre S, Cohen J, Bradburn M, Gray A, Benger J, Coats T, on behalf of the 3Mg Research Team. Intravenous or nebulised magnesium sulphate versus standard therapy for severe acute asthma (3Mg trial): a double-blind, randomised controlled trial. Lancet Respir Med 2013 1:293–300.


I am based in the Design, Trials & Statistics Section.