Using preference based measures in mental health conditions:

B Mulhern, C Mukuria, M Barkham, M Knapp, S Byford, D Soeteman, J Brazier


Background: Generic preference based measures (EQ-5D and SF-6D) can be used in the economic evaluation of mental health interventions. However there are inconsistent findings regarding the psychometric properties of the instruments.
Aims: To investigate the psychometric performance of the measures across a range of mental health conditions using seven existing datasets.
Methods: The feasibility, construct validity and responsiveness of the EQ-5D and SF-6D were assessed in comparison to condition specific indicators.
Results: Strong evidence for validity and responsiveness in common mental health and personality disorder samples was found. The psychometric performance in schizophrenia was more inconsistent.
Conclusions: EQ-5D and SF-6D can be used in the economic evaluation of interventions for common mental health problems and personality disorders with some confidence. In schizophrenia, the measurement of quality of life may be improved by developing a condition-specific preference based measure.
Declaration of interests: John Brazier developed SF-6D. Michael Barkham developed the CORE-OM.