Systematic Reviewing

Systematic reviews have been an important part of ScHARR's expertise for over a decade. In the 1990's our work informed the purchasing decisions of the NHS Trent Development and Evaluation Committee (DEC), a model which was later used as the prototype for the National Institute for Health and Care Excellence (NICE).

Much of our work programme informs health policy at the national level. Systematic reviewers in HEDS support the NICE technology appraisal programme through the production of technology assessment reports for multiple technology appraisals and evidence review group reports for single technology appraisals. We also produce reviews for the NICE decision support unit (DSU), the NICE Review of Interventional Procedures programme (ReBiP) and the NICE public health programme.

HEDS reviewers produce reviews for a variety of customers including the NIHR Evaluation, Trials and Studies Coordinating Centre (NETSCC), the Department of Health and others. Much of this work, together with our reviews for the international Cochrane Collaboration, underpins excellence in health care worldwide.

HEDS also supports local health care purchasers through the interim Excellence in Decision Making programme (previously the Evidence Based Commissioning Collaboration) and other initiatives.

A short course on systematic reviewing has been developed in HEDS. For details contact Andrea Shippam or 0114 22 20693.

Recently completed systematic reviews include:

  • Spinal cord stimulation for chronic pain of neuropathic or ischaemic origin (NICE) HTA monograph. Reviewer: Emma Simpson.
  • Amantadine, oseltamivir and zanamivir for the prophylaxis of influenza (including a review of existing guidance no. 67): a systematic review and economic evaluation (NICE) HTA monograph. Reviewer: Rachel Archer.
  • Lipid-lowering therapy to prevent cardiac events (NETSCC short report) HTA monograph. Reviewer: Abdullah Pandor.
  • A systematic review of the effectiveness and cost-effectiveness of interventions aimed at preventing medication error (medicines reconciliation) at hospital admission. Report. Reviewer: Fiona Campbell.
  • Looked after children. Projects. Reviewer: Roy Jones.

Ongoing systematic reviews include:

  • Vitamin K to prevent fractures in older women. (NETSCC) HTA monograph. Reviewer: Myfanwy Lloyd-Jones.
  • The role of enhanced imaging techniques in the assessment of axillary lymph node metastases. (NETSCC) HTA monograph. Reviewer: Katy Cooper.
  • Evaluate the clinical and cost effectiveness of group cognitive behavioural therapy for post-natal depression. (NETSCC) HTA monograph. Reviewer: Alison Scope.
  • Chemoprevention of colorectal cancer: systematic review and economic model. (NETSCC) HTA monograph. Reviewer: Chris Carroll.