‘Trials within Cohorts’ Symposium 2014

TwiCs Logo

10 - 11 November 2014

London School of Hygiene & Tropical Medicine, London

Manson Lecture Theatre

In association with NIHR CLAHRC Yorkshire and Humber, and NIHR CLAHRC North Thames


Home Presentations Speakers Programme     What are TwiCs?

Since the publication in 2010 of the innovative ‘cohort multiple randomised controlled trial’ design (, there has been growing interest in trials within cohorts. 

The purpose of this symposium was to advance the development and application of this design.  This event brought together triallists with practical experience of the ‘TwiCs’ design; providing an opportunity for them to share with others what they have learnt about the practical, ethical and statistical aspects of the design.


Symposium Committee

Clare Relton, Jan vander Meulen, Hashim Ahmed

Jon Nicholl, Kate Thomas, Maarten Burbach


Supported byNIHR CLAHRC North Thames and NIHR CLAHRC Yorkshire and Humber

The National Institute of Health Research (NIHR) has funded Collaborations for Leadership in Applied Health Research and Care (CLAHRCs) to conduct world class research that will have a direct impact on the health of patients with long term conditions and on the health of the public.

NIHR CLAHRCs are collaborations between partners, including world leading universities, the NHS, ASHNs, local authorities, patients, the public, industry and charities.

The NIHR CLAHRC North Thames covers the geographical area of north central and north east London, south and west Hertfordshire, south Bedfordshire and south west and mid-Essex. The NIHR CLAHRC Yorkshire and Humber encompasses the whole Yorkshire and Humber region.