Professor Mark E McAlindon


Clinical Medicine, School of Medicine and Population Health

Honorary Professor of Gastroenterology

Honorary Professor of Gastroenterology
+44 114 271 1900

Full contact details

Professor Mark E McAlindon
Clinical Medicine, School of Medicine and Population Health
Royal Hallamshire Hospital
Glossop Road
S10 2JF

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I qualified from the University of Nottingham in 1987 and trained in gastroenterology in Nottingham, Stoke-on-Trent, Melbourne (Australia).

In Melbourne I studied gastric adaptation to the effects of non-steroidal anti-inflammatory drugs (NSAIDs) in human subjects, using some of the techniques learnt to continue the same on my return to Nottingham where I subsequently became a British Digestive Foundation research training (1994-6) investigating the processing of interleukin-1 in inflammatory bowel disease.

I was appointed Consultant Gastroenterologist in Sheffield in 1998.

The Sheffield Small Bowel Service which I run with colleagues based on the Clinical Investigation Unit is the largest centre in the UK and one of the largest in Europe. It has received awards for innovation, service delivery and patient care from the British Medical Journal, the British Society of Gastroenterology, the Health Service Journal, Medipex and Movetis.

I was the recipient of the Hopkins Endoscopy Medal in 2017 for contributions to the field of endoscopy.

Research interests

My research interests are the roles of non-invasive technology, specifically capsule endoscopy, in the investigation of the gastrointestinal tract.

Capsule endoscopy is a first line modality for small bowel investigation and current projects address issues bowel preparation, the use of capsule endoscopes with two cameras at either end to improve lesion detection and the use of virtual reality to improve visualisation.

We are studying patient acceptability of different colonic imaging modalities to establish the role of colon capsule endoscopy as well as the use of panenteric capsule endoscopy.

Research into the use of capsule endoscopes in the upper gastrointestinal tract focusses on the use of magnetic control and automated lesion recognition in indications including dyspepsia, anaemia and acute upper gastrointestinal bleeding.


Current projects

  1. Patient acceptability of robot magnet-controlled upper gastrointestinal endoscopy.
  2. Handheld magnet controlled capsule endoscopy investigating anaemia and upper gastrointestinal bleeding.
  3. Upper gastrointestinal capsule endoscopy controlled with patient positional change.
  4. Virtual reality in capsule endoscopy.
  5. Gastric mapping of capsule endoscopy images.
  6. Patient acceptability of different colonic imaging modalities.

Show: Featured publications All publications

Journal articles

Conference proceedings papers

  • Hale MF, Drew K, Ejenavi E, Sidhu R & McAlindon ME (2015) PANENTERIC CAPSULE ENDOSCOPY: WHOLE GUT VISUALISATION WITHOUT INTUBATION. GUT, Vol. 64 (pp A26-A26) RIS download Bibtex download

All publications


  • (2014) Handbook of Capsule Endoscopy. Springer Netherlands. RIS download Bibtex download
  • Zhao H, Zhifeng L, Zhang H, Matsuno F, Guo Y, Mahadevan V, El Shahat A, Usman M, Young R, Xu H , Gen M et al (2012) Preface. RIS download Bibtex download

Journal articles


  • McAlindon ME, Hagenmüller F & Fleischer DE (2014) Fields of Application, Video Capsule Endoscopy (pp. 5-13). Springer Berlin Heidelberg RIS download Bibtex download
  • Hale MF & McAlindon M (2014) Future Development of Capsule Endoscopy, Handbook of Capsule Endoscopy (pp. 165-170). Springer Netherlands RIS download Bibtex download
  • Liao Z, Tang M, Guo Q, Wang B, He Q, Zhi F, McAlindon M, Carter D, Eliakim R, Koulaouzidis A , Douglas S et al (2014) Case Presentations, Handbook of Capsule Endoscopy (pp. 171-196). Springer Netherlands RIS download Bibtex download

Conference proceedings papers

Teaching activities

I have been a co-director of the European Lumley Castle Capsule Endoscopy Course since 2005, training over 700 delegates in capsule endoscopy and have taught at conferences and courses around Europe.

I organise the undergraduate gastroenterology module teaching for the University of Sheffield Dental School.

Professional activities and memberships
  • Ex-officio member of the British Society of Gastroenterology Endoscopy committee.
  • UK Clinical Lead for Quality Improvement in Small Bowel Endoscopy.
  • Member of the European Society of Gastroenterological Endoscopy Research Working Party.
  • Member of the European Society of Gastroenterological Endoscopy Quality Improvement Group (small bowel endoscopy section).
  • Trustee for the Bardhan Research and Educational Trust.