Emeritus Professor Rod Hose
BSc, PhD
Clinical Medicine, School of Medicine and Population Health
Emeritus Professor of Computational Biomechanics
Medical Physics Group
d.r.hose@sheffield.ac.uk
+44 114 215 9500
+44 114 215 9500
+44 114 271 1863
(fax)
The Medical School
Full contact details
Emeritus Professor Rod Hose
Clinical Medicine, School of Medicine and Population Health
The Medical School
Beech Hill Road
Sheffield
S10 2RX
Clinical Medicine, School of Medicine and Population Health
The Medical School
Beech Hill Road
Sheffield
S10 2RX
- Profile
-
For enquiries, please contact – iicd-om-operational@sheffield.ac.uk
After graduating in Mathematics from the University of Manchester, I worked as a structural analyst in the aerospace, motor vehicle and general engineering sectors. During this period I also completed my PhD in Applied Mechanics at the University of Manchester Institute of Science and Technology. I joined academia in 1992 as a lecturer in Aircraft Structures at the University of Salford.
I moved to Medical Physics at the University of Sheffield in 1994, where I was initially responsible for the development of undergraduate teaching in medical physics and had a primary research interest in the computational analysis of heart valve prostheses.
Prior to retirement I was Professor of Computational Biomechanics in the Mathematics and Modelling in Medicine Group in the Department of Infection, Immunity and Cardiovascular Disease at the University of Sheffield and concurrently Professor of Computational Cardiovascular Physiology in the Department of Circulation and Biomedical Engineering at NTNU in Trondhem.
I was awarded Dr Honoris Causa by the Technical University of Cluj-Napoca in 2014.
- Research interests
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My research interests are in the development of methods and workflows for the computational analysis of (primarily) cardiovascular systems, and in their translation to clinical application.
I am interested in all aspects of the process, from clinical data collection and management through image processing to the building of detailed three dimensional models of the vasculature and on to determination of appropriate boundary conditions, numerical solution and data reduction.
I have been intimately involved in the development of the European Commissions Virtual Physiological Human initiative from its beginning.
Current & Recent Projects
- VPH-Share.
- MD-Paedigree.
- HICF Grant.
- euHeart: Integrated Cardiac Care using Patient-Specific Cardiovascular Modeling. Funded by the European Community’s Seventh Framework Programme under the Information Society and Media’s Virtual Physiological Human initiative. Grant agreement 224495.
- Translating Biomedical Modelling to the Heart of the Clinic Funded by the EPSRC under its Digital Economy programme in the Grand Challenges in IT for Healthcare initiative.
- Virtual Physiological Human Network of Excellence. Funded by the European Community’s Seventh Framework Programme under the Information Society and Media’s Virtual Physiological Human initiative.
- Collaborator with the NIHR Sheffield Cardiovascular Biomedical Research Unit
- The Virtual Tendon: a multiscale computational model of dynamic tissue remodelling. Funded by Arthritis Research Campaign
- @neurIST: Integrated Biomedical Informatics for Management of Cerebral Aneurysms (2006-2010), Funded by the European Community’s Sixth Framework Programme by DG-Infso.
- EurValve
- i4i (National Institute for Health Research, Invention for Innovation (i4i). Gunn JP, Morris PD, Hose DR, Lawford PV. ‘A prototype tool to calculate 'virtual' myocardial fractional flow reserve (vFFR) non-invasively (VIRTU-3)’. March 2017 – March 2019.
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- Virtual Coronary Intervention. A Treatment Planning Tool Based Upon the Angiogram. JACC: Cardiovascular Imaging, 12(5), 865-872. View this article in WRRO
- What is needed to make cardiovascular models suitable for clinical decision support? A viewpoint paper. Journal of Computational Science, 24, 68-84.
- Fast Virtual Fractional Flow Reserve Based Upon Steady-State Computational Fluid Dynamics Analysis: Results From the VIRTU-Fast Study. JACC: Basic to Translational Science, 2(4), 434-446. View this article in WRRO
- CFD- and Bernoulli-based pressure drop estimates: A comparison using patient anatomies from heart and aortic valve segmentation of CT images. Medical Physics, 44(6), 2281-2292. View this article in WRRO
- Making sense of big data in health research: Towards an EU action plan. Genome Medicine, 8:71. View this article in WRRO
- Diagnosis of Pulmonary Hypertension from Magnetic Resonance Imaging–Based Computational Models and Decision Tree Analysis. Pulmonary Circulation, 6(2), 181-190. View this article in WRRO
- Computational fluid dynamics modelling in cardiovascular medicine. Heart, 102(1), 18-28. View this article in WRRO
- Big Data, Big Knowledge: Big Data for Personalized Healthcare. IEEE Journal of Biomedical and Health Informatics, 19(4), 1209-1215. View this article in WRRO
- “Virtual” (Computed) Fractional Flow Reserve. JACC: Cardiovascular Interventions, 8(8), 1009-1017. View this article in WRRO
- MRI model-based non-invasive differential diagnosis in pulmonary hypertension. Journal of Biomechanics, 47(12), 2941-2947. View this article in WRRO
- Virtual fractional flow reserve from coronary angiography: modeling the significance of coronary lesions: results from the VIRTU-1 (VIRTUal Fractional Flow Reserve From Coronary Angiography) study.. JACC Cardiovasc Interv, 6(2), 149-157.
- Accuracy vs. computational time: Translating aortic simulations to the clinic. Journal of Biomechanics, 45(3), 516-523.
- An accurate, fast and robust method to generate patient-specific cubic Hermite meshes.. Med Image Anal, 15(6), 801-813.
- Computational modelling and evaluation of cardiovascular response under pulsatile impeller pump support. INTERFACE FOCUS, 1(3), 320-337.
- euHeart: personalized and integrated cardiac care using patient-specific cardiovascular modelling. INTERFACE FOCUS, 1(3), 349-364.
- @neurIST Complex Information Processing toolchain for the integrated management of cerebral aneurysm. Journal of the Royal Society Interface(1), 308-319.
All publications
Books
- Medical Physics and Biomedical Engineering. IOP Publishing Ltd.
- Medical Physics and Biomedical Engineering. CRC Press.
Journal articles
- Wearable devices can predict the outcome of standardized 6-minute walk tests in heart disease. npj Digital Medicine, 3(1).
- A novel method for measuring absolute coronary blood flow & microvascular resistance in patients with ischaemic heart disease. Cardiovascular Research. View this article in WRRO
- Validation of four-dimensional flow cardiovascular magnetic resonance for aortic stenosis assessment. Scientific Reports, 10(1). View this article in WRRO
- Effect of side branch flow upon physiological indices in coronary artery disease. Journal of Biomechanics. View this article in WRRO
- Subject-specific simulation for non-invasive assessment of aortic coarctation: Towards a translational approach. Medical Engineering and Physics. View this article in WRRO
- Cardiovascular models for personalised medicine: Where now and where next?. Medical Engineering and Physics, 72, 38-48. View this article in WRRO
- Expert recommendations on the assessment of wall shear stress in human coronary arteries : existing methodologies, technical considerations, and clinical applications. European Heart Journal, 40(41), 3421-3433. View this article in WRRO
- A systematic review of 4D-flow MRI derived mitral regurgitation quantification methods. Frontiers in Cardiovascular Medicine, 6. View this article in WRRO
- Patient-specific non-invasive estimation of pressure gradient across aortic coarctation using magnetic resonance imaging. Journal of Cardiology, 73(Semin Thorac Cardiovasc Surg 17 2005), 544-552.
- 60 An atlas of computed FFR in common patterns of coronary artery disease. Heart, 105(Suppl 6), a51-a51. View this article in WRRO
- 17 Computational modelling of fractional flow reserve from coronary angiography : expert training required. Heart, 105(Suppl 6), a15-a15. View this article in WRRO
- 16 Assessing the accuracy of a novel in silico imaging tool for the 3D reconstruction of coronary vasculature in the context of virtual fractional flow reserve. Heart, 105(Suppl 6), a14-a14. View this article in WRRO
- Virtual Coronary Intervention. A Treatment Planning Tool Based Upon the Angiogram. JACC: Cardiovascular Imaging, 12(5), 865-872. View this article in WRRO
- Construction of lumped-parameter cardiovascular models using the CellML language. Journal of Medical Engineering & Technology, 42(7), 525-531.
- Personalised Fractional Flow Reserve: Novel Concept to Optimise Myocardial Revascularization.. EuroIntervention. View this article in WRRO
- Predictive Physiological Modeling of Percutaneous Coronary Intervention – Is Virtual Treatment Planning the Future?. Frontiers in Physiology, 9, 1107-1107. View this article in WRRO
- An asymmetric wall-thickening pattern predicts response to cardiac resynchronization therapy. JACC: Cardiovascular Imaging. View this article in WRRO
- The Impact of Objective Mathematical Analysis During Fractional Flow Reserve Measurement. Eurointervention. View this article in WRRO
- An automatic method for aortic segmentation based on level-set methods using multiple seed points. Lecture Notes in Computational Vision and Biomechanics, 27, 875-882.
- What is needed to make cardiovascular models suitable for clinical decision support? A viewpoint paper. Journal of Computational Science, 24, 68-84.
- Heart rate reduction with ivabradine promotes shear stress-dependent anti-inflammatory mechanisms in arteries. Thrombosis and Haemostasis, 116(1), 181-190. View this article in WRRO
- Fast Virtual Fractional Flow Reserve Based Upon Steady-State Computational Fluid Dynamics Analysis: Results From the VIRTU-Fast Study. JACC: Basic to Translational Science, 2(4), 434-446. View this article in WRRO
- P842A novel mathematical signal processing application which automates and improves the accuracy of FFR assessment. European Heart Journal, 38(suppl_1).
- A cell-based mechanical model of coronary artery tunica media. Journal of The Royal Society Interface, 14(132), 20170028-20170028.
- CFD- and Bernoulli-based pressure drop estimates: A comparison using patient anatomies from heart and aortic valve segmentation of CT images. Medical Physics, 44(6), 2281-2292. View this article in WRRO
- Making sense of big data in health research: Towards an EU action plan. Genome Medicine, 8:71. View this article in WRRO
- Erratum to: Making sense of big data in health research: towards an EU action plan. Genome Medicine, 8(1).
- Diagnosis of Pulmonary Hypertension from Magnetic Resonance Imaging–Based Computational Models and Decision Tree Analysis. Pulmonary Circulation, 6(2), 181-190. View this article in WRRO
- Computational fluid dynamics modelling in cardiovascular medicine. Heart, 102(1), 18-28. View this article in WRRO
- Big Data, Big Knowledge: Big Data for Personalized Healthcare. IEEE Journal of Biomedical and Health Informatics, 19(4), 1209-1215. View this article in WRRO
- “Virtual” (Computed) Fractional Flow Reserve. JACC: Cardiovascular Interventions, 8(8), 1009-1017. View this article in WRRO
- Closing the Loop: Modelling of Heart Failure Progression from Health to End-Stage Using a Meta-Analysis of Left Ventricular Pressure-Volume Loops. PLoS ONE, 9(12), e114153-e114153. View this article in WRRO
- MRI model-based non-invasive differential diagnosis in pulmonary hypertension. Journal of Biomechanics, 47(12), 2941-2947. View this article in WRRO
- From Histology and Imaging Data to Models for In-Stent Restenosis. The International Journal of Artificial Organs, 37(10), 786-800.
- Contribution of Mechanical and Fluid Stresses to the Magnitude of In-stent Restenosis at the Level of Individual Stent Struts. Cardiovascular Engineering and Technology, 5(2), 164-175.
- Identification of artery wall stiffness: in vitro validation and in vivo results of a data assimilation procedure applied to a 3D fluid-structure interaction model.. J Biomech, 47(5), 1027-1034.
- Derivation of aortic distensibility and pulse wave velocity by image registration with a physics-based regularisation term. International Journal for Numerical Methods in Biomedical Engineering.
- Risk of Rupture of Small Anterior Communicating Artery Aneurysms Is Similar to Posterior Circulation Aneurysms. Stroke, 44(11), 3018-3026.
- Share and enjoy: Anatomical models database - Generating and sharing cardiovascular model data using web services. Medical and Biological Engineering and Computing, 51(11), 1181-1190. View this article in WRRO
- A patient-specific study of type-B aortic dissection: evaluation of true-false lumen blood exchange.. Biomed Eng Online, 12, 65. View this article in WRRO
- A vision and strategy for the virtual physiological human: 2012 update. INTERFACE FOCUS, 3(2).
- Virtual fractional flow reserve from coronary angiography: modeling the significance of coronary lesions: results from the VIRTU-1 (VIRTUal Fractional Flow Reserve From Coronary Angiography) study.. JACC Cardiovasc Interv, 6(2), 149-157.
- Generating anatomical models of the heart and the aorta from medical images for personalized physiological simulations.. Med Biol Eng Comput, 51(11), 1209-1219.
- Measuring three-dimensional strain distribution in tendon. Journal of Microscopy, 249(3), 195-205.
- Guest editorial special issue on medical imaging and image computing in computational physiology. IEEE Transactions on Medical Imaging, 32(1), 1-7.
- Quality metrics for high order meshes: analysis of the mechanical simulation of the heart beat.. IEEE Trans Med Imaging, 32(1), 130-138.
- A method for the automated processing and analysis of images of ULVWF-platelet strings.. Platelets, 24(3), 226-234.
- ONE-DIMENSIONAL SIMULATION OF HAEMODYNAMICS IN AORTIC COARCTATION. Journal of Biomechanics, 45, S38-S38.
- CFD ANALYSIS OF THE REGURGITANT FLOW IN A BILEAFLET MECHANICAL HEART VALVE. Journal of Biomechanics, 45, S130-S130.
- INFLUENCE OF STENT STRUT DISTRIBUTION ON LOCAL VESSEL STRESS. Journal of Biomechanics, 45, S25-S25.
- Accuracy vs. computational time: Translating aortic simulations to the clinic. Journal of Biomechanics, 45(3), 516-523.
- Towards collaborative data management in the VPH-Share project. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 7155 LNCS(PART 1), 54-63.
- Computational fluid dynamic analysis of the regurgitant flow in a bileaflet mechanical heart valve. ECCOMAS 2012 - European Congress on Computational Methods in Applied Sciences and Engineering, e-Book Full Papers, 7982-7989.
- Importance of realistic LVAD profiles for assisted aortic simulations: evaluation of optimal outflow anastomosis locations.. Comput Methods Biomech Biomed Engin, 15(6), 669-680.
- Predicting hemodynamics in native and residual coarctation: preliminary results of a Rigid-Wall Computational-Fluid-Dynamics model (RW-CFD) validated against clinically invasive pressure measures at rest and during pharmacological stress. Journal of Cardiovascular Magnetic Resonance, 13(S1).
- An accurate, fast and robust method to generate patient-specific cubic Hermite meshes.. Med Image Anal, 15(6), 801-813.
- Computational modelling and evaluation of cardiovascular response under pulsatile impeller pump support. INTERFACE FOCUS, 1(3), 320-337.
- Multi-scale simulations of the dynamics of in-stent restenosis: impact of stent deployment and design. INTERFACE FOCUS, 1(3), 365-373.
- euHeart: personalized and integrated cardiac care using patient-specific cardiovascular modelling. INTERFACE FOCUS, 1(3), 349-364.
- Three-dimensional morphological analysis of intracranial aneurysms: A fully automated method for aneurysm sac isolation and quantification. MED PHYS, 38(5), 2439-2449.
- Review of zero-D and 1-D models of blood flow in the cardiovascular system.. Biomed Eng Online, 10, 33-33. View this article in WRRO
- @neurIST Complex Information Processing toolchain for the integrated management of cerebral aneurysm. Journal of the Royal Society Interface(1), 308-319.
- Multi-scale interaction of particulate flow and the artery wall. Medical Engineering and Physics, 33(7), 840-848.
- Patient-Specific Modeling of Cerebral Blood Flow: Geometrical Variations in a 1D Model. Cardiovascular Engineering and Technology, 2(4), 334-348.
- A Complex Automata approach for in-stent restenosis: Two-dimensional multiscale modelling and simulations. Journal of Computational Science.
- Multi-scale interaction of particulate flow and the artery wall.. Med Eng Phys, 33(7), 840-848.
- Computational hemodynamics in cerebral aneurysms: the effects of modeled versus measured boundary conditions.. Ann Biomed Eng, 39(2), 884-896.
- Effects of smoking and hypertension on wall shear stress and oscillatory shear index at the site of intracranial aneurysm formation.. Clin Neurol Neurosurg, 112(4), 306-313.
- Effects of heparin on the hemodynamic characteristics of intracranial aneurysms.. J Neuroradiol, 37(5), 300-301.
- Numerical modeling of hemodynamics with pulsatile impeller pump support.. Ann Biomed Eng, 38(8), 2621-2634.
- Analysis of a mechanical heart valve prosthesis and a native venous valve: Two distinct applications of FSI to biomedical applications. INT J NUMER METH BIO, 26(3-4), 421-434.
- Automated intracranial aneurysm isolation and quantification.. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2841-2844.
- The effects of aortic coarctation on cerebral hemodynamics and its importance in the etiopathogenesis of intracranial aneurysms.. J Vasc Interv Neurol, 3(1), 17-30.
- @neurIST: Infrastructure for advanced disease management through integration of heterogeneous data, computing, and complex processing services. IEEE Transactions on Information Technology in Biomedicine, 14(6), 1365-1377.
- Personalization of cubic hermite meshes for efficient biomechanical simulations. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 6362 LNCS(PART 2), 380-387.
- Acquisition of 3-D arterial geometries and integration with computational fluid dynamics.. Ultrasound Med Biol, 35(12), 2069-2083.
- Simulations of time harmonic blood flow in the Mesenteric artery: comparing finite element and lattice Boltzmann methods.. BioMedical Engineering OnLine, 8. View this article in WRRO
- Influence of inlet boundary conditions on the local haemodynamics of intracranial aneurysms.. Comput Methods Biomech Biomed Engin, 12(4), 431-444.
- Adaptation and development of software simulation methodologies for cardiovascular engineering: present and future challenges from an end-user perspective.. Philos Trans A Math Phys Eng Sci, 367(1898), 2655-2666.
- Automated tracking of migrating cells in phase-contrast video microscopy sequences using image registration.. J Microsc, 234(1), 62-79.
- A validated model of calf compression and deep vessel collapse during external cuff inflation.. IEEE Trans Biomed Eng, 56(2), 273-280.
- Nodal positions displacement sensitivity of an elementary icosahedron tensegrity structure. Computational Plasticity X - Fundamentals and Applications.
- CellML implementation of a numerical model for the cardiovascular system under VAD support. IFMBE Proceedings, 25(4), 1796-1799.
- Systemic modelling and computational physiology: The application of Bond Graph boundary conditions for 3D cardiovascular models. SIMUL MODEL PRACT TH, 17(1), 125-136.
- The role of computational fluid dynamics in the management of unruptured intracranial aneurysms: a clinicians' view.. Comput Intell Neurosci, 760364. View this article in WRRO
- Modelling the interaction of haemodynamics and the artery wall: current status and future prospects.. Biomed Pharmacother, 62(8), 530-535.
- The application of multiscale modelling to the process of development and prevention of stenosis in a stented coronary artery.. Philos Trans A Math Phys Eng Sci, 366(1879), 3343-3360.
- The EuroPhysiome, STEP and a roadmap for the virtual physiological human.. Philos Trans A Math Phys Eng Sci, 366(1878), 2979-2999.
- Reproducibility of haemodynamical simulations in a subject-specific stented aneurysm model--a report on the Virtual Intracranial Stenting Challenge 2007.. J Biomech, 41(10), 2069-2081.
- MULTISCALE MODELLING: APPLICATION OF THE COMPLEX AUTOMATA SIMULATION TECHNIQUE (COAST). Journal of Biomechanics, 41, S482-S482.
- A NOVEL TECHNIQUE FOR INVESTIGATING PROPERTIES OF ULVWF-PLATELET COMPLEXES. Journal of Biomechanics, 41, S182-S182.
- A VALIDATED MODEL OF VENOUS FLOW AUGMENTATION DURING INTERMITTENT PNEUMATIC COMPRESSION. Journal of Biomechanics, 41, S270-S270.
- MULTI-PHYSICS & MULTI-SCALE MODELLING: CLOSURE DYNAMICS OF A BILEAFLET PROSTHETIC HEART VALVE. Journal of Biomechanics, 41, S241-S241.
- GRAVITY AND VENOUS VALVE BLOOD “WASH OUT”: A 3D MODEL. Journal of Biomechanics, 41, S272-S272.
- GRID SIMULATION SERVICES FOR THE MEDICAL COMMUNITY. INT J COMPUT METHODS, 5(2), 289-317.
- The role of venous valves in pressure shielding.. Biomed Eng Online, 7, 8. View this article in WRRO
- Special issue on imaging and the virtual physiological human. IEEE Transactions on Medical Imaging, 27(5).
- Special issue on imaging and the virtual physiological human. IEEE Transactions on Medical Imaging, 27(6), 874.
- @neurIST - Chronic disease management through integration of heterogeneous data and computer-interpretable guideline services. Studies in Health Technology and Informatics, 138, 173-177.
- The @neurIST project. Studies in Health Technology and Informatics, 138, 161-164.
- Multiphysics and multiscale simulation: Application to a coupled model of the left ventricle and a mechanical heart valve. INT J MULTISCALE COM, 6(1), 65-76.
- A lattice Boltzmann framework for simulation of thrombogenesis. PROG COMPUT FLUID DY, 8(1-4), 121-128.
- Efficient computational fluid dynamics mesh generation by image registration.. Med Image Anal, 11(6), 648-662.
- Quantitative evaluation of free-form deformation registration for dynamic contrast-enhanced MR mammography.. Med Phys, 34(4), 1221-1233.
- A framework for the modeling of gut blood flow regulation and postprandial hyperaemia.. World J Gastroenterol, 13(9), 1393-1398.
- The @neurIST project: towards understanding cerebral aneurysms. SPIE Newsroom.
- A lattice boltzmann HPC application in medical physics. High Performance Computing on Vector Systems 2006 - Proceedings of the High Performance Computing Center, 121-132.
- Balloon folding affects the symmetry of stent deployment: Experimental and computational evidence. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, 3069-3073.
- Influence of intermittent compression cuff design on interface pressure and calf deformation: experimental results.. Conf Proc IEEE Eng Med Biol Soc, 2007, 2122-2125.
- Balloon folding affects the symmetry of stent deployment: experimental and computational evidence.. Conf Proc IEEE Eng Med Biol Soc, 2007, 3069-3073.
- Influence of intermittent compression cuff design on calf deformation: computational results.. Conf Proc IEEE Eng Med Biol Soc, 2007, 6334-6338.
- Characterisation of the haemodynamics of the superior mesenteric artery.. J Biomech, 40(9), 1916-1926.
- Application and validation of the lattice Boltzmann method for modelling flow-related clotting.. J Biomech, 40(13), 3023-3028.
- Factors influencing the accuracy of biomechanical breast models.. Med Phys, 33(6), 1758-1769.
- Computer modelling study of the mechanism of optic nerve injury in blunt trauma.. Br J Ophthalmol, 90(6), 778-783.
- Coupling a bond graph model of the left ventricle with a CFX model of the aorta: a first approach. Journal of Biomechanics, 39, S295-S295.
- Effect of cardiac motion on haemodynamics in the superior mesenteric artery (SMA). Journal of Biomechanics, 39, S611-S611.
- Computer simulation of blunt trauma to the eye and the optic nerve. Journal of Biomechanics, 39, S535-S535.
- Computation of closure forces for mechanical heart valves. Journal of Biomechanics, 39, S305-S305.
- Mass transport across the arterial wall from drug eluting stents. Journal of Biomechanics, 39, S633-S633.
- A modelling framework to predict haemodynamics in the deep veins of the calf during external intermittent compression therapy. Journal of Biomechanics, 39, S281-S281.
- Ultrasound investigation of lower limb haemodynamics during compression using a water-filled cuff. Journal of Biomechanics, 39, S301-S302.
- The epitheliome: individual-based modelling of emergent behaviour resulting from cellular interaction. Journal of Biomechanics, 39, S437-S437.
- Concurrent numerical simulation of flow and blood clotting using the lattice Boltzmann technique.. Int J Bioinform Res Appl, 2(4), 371-380.
- Outlook for grid service technologies within the @neurIST eHealth environment.. Stud Health Technol Inform, 120, 401-404.
- Fundamental mechanics of aortic heart valve closure.. J Biomech, 39(5), 958-967.
- Relative importance of the components of stent geometry to stretch induced in-stent neointima formation.. Heart, 91(12), 1603-1604.
- Automatic segmentation of medical images using image registration: diagnostic and simulation applications.. J Med Eng Technol, 29(2), 53-63.
- A computational study of the passive mechanisms of eye restraint during head impact trauma.. Comput Methods Biomech Biomed Engin, 8(1), 1-6.
- Development and validation of models for the investigation of blood clotting in idealized stenoses and cerebral aneurysms.. J Artif Organs, 8(1), 56-62.
- A computational and experimental study on the mechanism of eye restraint during acceleration trauma. Proceedings of the 2005 Summer Bioengineering Conference, 2005, 419-420.
- Mechanistic hypothesis for eye injury in infant shaking: An experimental and computational study. Forensic Science, Medicine, and Pathology, 1(1), 53-59.
- A simple Computational Model-Based Validation of Guyton's closed circuit analysis of the heart and the peripheral circulatory system.. Conf Proc IEEE Eng Med Biol Soc, 2005, 5486-5489.
- A thermal analogy for modelling drug elution from cardiovascular stents.. Comput Methods Biomech Biomed Engin, 7(5), 257-264.
- The epitheliome: agent-based modelling of the social behaviour of cells.. Biosystems, 76(1-3), 89-100. View this article in WRRO
- Modelling of epithelial tissue impedance measured using three different designs of probe.. Physiol Meas, 24(2), 605-623.
- Measurement of the symmetry of in vitro stent expansion: a stereo-photogrammetric approach.. J Med Eng Technol, 27(2), 59-70.
- Validation of nonrigid image registration using finite-element methods: application to breast MR images.. IEEE Trans Med Imaging, 22(2), 238-247.
- Fluid-solid interaction: benchmarking of an external coupling of ANSYS with CFX for cardiovascular applications.. J Med Eng Technol, 27(1), 23-31.
- Radiological imaging as the basis for a simulation software of ventilation in the tracheo-bronchial tree.. Eur Radiol, 12(9), 2218-2228.
- Development of an accurate three-dimensional finite element knee model.. Comput Methods Biomech Biomed Engin, 5(4), 291-300.
- Tomographic imaging and scanning thermal microscopy: thermal impedance tomography. THERMOCHIM ACTA, 385(1-2), 19-32. View this article in WRRO
- The sequence of reflex sympathetic dystrophy. J HAND SURG-BRIT EUR, 27B(1), 109-110.
- Resistivity changes in conductive silicone sheets under stretching.. Physiol Meas, 23(1), 183-188.
- Modelled current distribution in cervical squamous tissue.. Physiol Meas, 23(1), 159-168.
- Letter to the editor (multiple letters). Journal of Hand Surgery, 27 B(1), 108-110.
- Constraints on tetrapolar tissue impedance measurements. ELECTRON LETT, 37(25), 1515-1517.
- Outlet strut fracture of Björk-Shiley convexo-concave valves: can valve-manufacturing characteristics explain the risk?. J Thorac Cardiovasc Surg, 121(6), 1143-1149.
- Medical Physics and Biomedical Engineering. Medical Physics, 28(5), 861-861.
- Modelling the electrical impedivity of normal and premalignant cervical tissue. ELECTRON LETT, 36(19), 1603-1604.
- Development of an ex vivo model to investigate the effects of altered haemodynamics on human bypass grafts.. J Med Eng Technol, 24(5), 183-191.
- Stable periodic vortex shedding studied using computational fluid dynamics, laser sheet flow visualization, and MR imaging.. Magn Reson Imaging, 18(4), 473-478.
- A goniometric glove for clinical hand assessment. Construction, calibration and validation.. J Hand Surg Br, 25(2), 200-207.
- Computer model analysis of the Swanson and Sutter metacarpophalangeal joint implants.. J Hand Surg Br, 25(2), 212-220.
- An inexpensive sensor for measuring surface geometry.. Med Eng Phys, 21(10), 725-729.
- An impact analysis of a flexible bat using an iterative solver.. J Sports Sci, 17(8), 677-682.
- Can we optimize electrode placement for impedance pneumography?. Ann N Y Acad Sci, 873, 534-542.
- Frequency dependent modelling of single motor unit surface potentials. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, 1, 579.
- Anatomical and physiological models for surgical simulation.. Stud Health Technol Inform, 62, 23-29.
- In-situ simulation of one-piece metacarpophalangeal joint implants using finite element analysis.. Med Eng Phys, 19(4), 303-307.
- Fracture of glass-reinforced plastic pipes of mixed wall construction under pressure loading. P I MECH ENG E-J PRO, 211(E4), 223-246.
- An examination of one-piece metacarpophalangeal joint implants using finite element analysis.. J Med Eng Technol, 20(4-5), 145-150.
- The use of enzyme activated milk for in vitro simulation of prosthetic valve thrombosis.. J Heart Valve Dis, 5(1), 74-83.
- The origin and significance of secondary flows in the aortic arch.. J Med Eng Technol, 19(6), 192-197.
- Prosthetic heart valves--the integration of analysis with design.. J Heart Valve Dis, 4 Suppl 1, S50-S54.
- EXPERIMENTAL AND THEORETICAL STRESS-ANALYSIS OF MULTI-MITRED LINED GLASS-REINFORCED PLASTIC PIPE BENDS. INT J MECH SCI, 37(2), 97-119.
- Book Review: Fine Element Analysis: Theory and Practice. International Journal of Mechanical Engineering Education, 23(1), 48-48.
- In vitro heart valve testing: steady versus pulsatile flow.. J Heart Valve Dis, 3(2), 212-215.
- BEHAVIOR OF GRP SMOOTH PIPE BENDS WITH TANGENT PIPES UNDER FLEXURE OR PRESSURE LOADS - A COMPARISON OF ANALYSES BY CONVENTIONAL AND FINITE-ELEMENT TECHNIQUES. INT J MECH SCI, 35(7), 549-575.
- THE INFLUENCE OF THE VARIATION IN WALL THICKNESS OF GLASS-FIBER REINFORCED PLASTIC PIPE BENDS SUBJECTED TO INPLANE BENDING. J STRAIN ANAL ENG, 27(2), 113-121.
- Use of numerical methods in the investigation of valve cleanability. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED, 23, 103-105.
- Use of numerical methods in valve design for bioprocessing. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED, 21, 87-91.
- LAMINATED PIPE BENDS OF MIXED WALL CONSTRUCTION SUBJECTED TO AN INPLANE BENDING MOMENT. J STRAIN ANAL ENG, 24(3), 127-138.
- GLASS REINFORCED COMPOSITES OF MIXED WALL CONSTRUCTION. INT J PRES VES PIP, 27(4), 305-323.
- Estimation of valvular resistance of segmented aortic valves using computational fluid dynamics. Journal of Biomechanics. View this article in WRRO
Chapters
- The Arterial System I. Pressure, Flow and Stiffness, Cardiovascular Biomechanics (pp. 65-81). Springer International Publishing
- Excitation-Contraction in the Heart, Cardiovascular Biomechanics (pp. 107-126). Springer International Publishing
- Modelling of the Cardiovascular System, Cardiovascular Biomechanics (pp. 193-205). Springer International Publishing
Conference proceedings papers
- Virtual (computed) FFR and Virtual Coronary Intervention (VCI) vs angiography for guiding PCI: a virtual study.. Heart, Vol. 105(Suppl 6) (pp a45-a45). Manchester, UK, 3 June 2019 - 5 June 2019. View this article in WRRO
- A novel mathematical signal processing application which automates and improves the accuracy of FFR assessment. EUROPEAN HEART JOURNAL, Vol. 38 (pp 183-184) View this article in WRRO
- Three Element Windkessel Model to Non-Invasively Assess PAH Patients: One Year Follow-up (pp 151-154)
- Response to treatment assessment in patients with PAH by MRI based computational modelling. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases
- Diagnosis of pulmonary hypertension from MR image based computational models of pulmonary vascular haemodynamics and decision tree analysis. 4.3 Pulmonary Circulation and Pulmonary Vascular Disease
- 209 The Development and Validation of anin silicoModel of Coronary Arterial Physiology for Diagnostic Use. Heart, Vol. 101(Suppl 4) (pp A115.1-A115)
- Comparison of CFD-Based and Bernoulli-Based Pressure Drop Estimates across the Aortic Valve Enabled by Shape-Constrained Deformable Segmentation of Cardiac CT Images (pp 211-219)
- Automatic, Simultaneous, Non-invasive Measurements of Flow and Area in the Human Pulmonary Arteries from MRI Images (pp 259-264)
- COMPUTER MODELLED CORONARY PHYSIOLOGY AND "VIRTUAL" FRACTIONAL FLOW RESERVE FROM ROTATIONAL ANGIOGRAPHY. HEART, Vol. 98 (pp A14-A14)
- 3D reconstruction of coronary arteries from rotational X-ray angiography. Proceedings - International Symposium on Biomedical Imaging (pp 618-621)
- Virtual Coronary Physiology and Anatomy Derived From Rotational Angiography: The First Step. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol. 58(20) (pp B189-B189)
- CFD Analysis Study on the Impact of the Coronary Anatomy on the Efficiency of the Coronary Thrombectomy: The Effect of Bend Angles (pp 306-309)
- Multi-physics and Multi-scale Computational Evaluation of the Thrombogenic and Cavitational Potential of a Bileaflet Mechanical Heart Valve (pp 298-305)
- Modelling the Development of In-Stent Restenosis: Preliminary Results of a Structural Model. INTERNATIONAL CONFERENCE ON ADVANCEMENTS OF MEDICINE AND HEALTH CARE THROUGH TECHNOLOGY, Vol. 36 (pp 276-279)
- A vision and strategy for the virtual physiological human in 2010 and beyond. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, Vol. 368(1920) (pp 2595-2614)
- Automated intracranial aneurysm isolation and quantification.. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, Vol. 2010 (pp 2841-2844)
- Automated intracranial aneurysm isolation and quantification. 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 (pp 2841-2844)
- EXPERIMENTAL STUDIES AND NUMERICAL SIMULATIONS OF SOME MECHANICAL HEART VALVES' BIOMECHANICS. MANAGEMENT OF TECHNOLOGICAL CHANGES, VOL 1 (pp 445-448)
- COAST: Modelling Restenosis and Stent Based Therapies. INTERNATIONAL CONFERENCE ON ADVANCEMENTS OF MEDICINE AND HEALTH CARE THROUGH TECHNOLOGY, Vol. 26 (pp 319-322)
- Determination of Wall Strain in Model Cerebral Aneurysms by Image Registration. INTERNATIONAL CONFERENCE ON ADVANCEMENTS OF MEDICINE AND HEALTH CARE THROUGH TECHNOLOGY, Vol. 26 (pp 283-286)
- Closure Mechanics of Mechanical Heart Valve Prostheses - Experimental and Computational Analysis. INTERNATIONAL CONFERENCE ON ADVANCEMENTS OF MEDICINE AND HEALTH CARE THROUGH TECHNOLOGY, Vol. 26 (pp 363-368)
- Towards a Complex Automata Multiscale Model of In-Stent Restenosis.. ICCS (1), Vol. 5544 (pp 705-714)
- Applying the lattice Boltzmann technique to biofluids: A novel approach to simulate blood coagulation. COMPUTERS & MATHEMATICS WITH APPLICATIONS, Vol. 55(7) (pp 1408-1414)
- @neurIST - Towards a system architecture for advanced disease management through integration of heterogeneous data, computing, and complex processing services. Proceedings - IEEE Symposium on Computer-Based Medical Systems (pp 361-366)
- The Karman Vortex in a Medical Imaging Context: A Validated Computational Model of Laminar Shedding.. MSV (pp 185-190)
- Investigations of the thrombogenic and cavitational potentials of a bileaflet mechanical heart valve, using ANSYS-CFX. 2008 IEEE INTERNATIONAL CONFERENCE ON AUTOMATION, QUALITY AND TESTING, ROBOTICS (AQTR 2008), THETA 16TH EDITION, VOL III, PROCEEDINGS (pp 106-111)
- Development of a lattice Boltzmann framework for numerical simulation of thrombosis. INTERNATIONAL JOURNAL OF MODERN PHYSICS C, Vol. 18(4) (pp 483-491)
- A 3D ultrasound system for image guided modeling of patient-specific artery geometries. 2007 IEEE ULTRASONICS SYMPOSIUM PROCEEDINGS, VOLS 1-6 (pp 2469-2472)
- The Cavitational Potential of a Single-leaflet Virtual MHV: A Multi-Physics and Multiscale Modelling Approach. 11TH MEDITERRANEAN CONFERENCE ON MEDICAL AND BIOLOGICAL ENGINEERING AND COMPUTING 2007, VOLS 1 AND 2, Vol. 16(1-2) (pp 895-898)
- Digital human modelling: A global vision and a European perspective. Digital Human Modeling, Vol. 4561 (pp 549-558)
- Multi-physics and multi-scale modelling in cardiovascular physiology: Advanced user methods for simulation of biological systems with ANSYS/CFX. Computational Science - ICCS 2007, Pt 1, Proceedings, Vol. 4487 (pp 794-801)
- Numerical simulation of clotting processes: A lattice Boltzmann application in medical physics. MATHEMATICS AND COMPUTERS IN SIMULATION, Vol. 72(2-6) (pp 89-92)
- MRI studies of blood flow in the superior mesenteric artery (SMA). GASTROENTEROLOGY, Vol. 130(4) (pp A196-A196)
- MRI studies of blood flow through the superior mesenteric artery. GUT, Vol. 55 (pp A114-A114)
- Gut blood flow: Modelling the dynamic anatomy of the superior mesenteric artery (SMA). GASTROENTEROLOGY, Vol. 128(4) (pp A656-A656)
- Concurrent numerical simulation of flow and blood clotting using the lattice Boltzmann technique. 11th International Conference on Parallel and Distributed Systems Workshops, Vol II, Proceedings, (pp 336-340)
- A computational study of the optic nerve evulsion. IUTAM Symposium on Impact Biomechanics: From Fundamental Insights to Applications, Vol. 124 (pp 469-476)
- Modeling of the eye and orbit to simulate Shaken Baby syndrome. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol. 46
- A registration based mesh construction technique for finite element models of brains. MEDICAL IMAGING 2002: IMAGE PROCESSING, VOL 1-3, Vol. 4684 (pp 538-549)
- Validation of Nonrigid Registration of Contrast-Enhanced MR Mammography Using Finite Element Methods.. Bildverarbeitung für die Medizin, Vol. 56 (pp 143-146)
- Comparison of biomechanical breast models: a case study. MEDICAL IMAGING 2002: IMAGE PROCESSING, VOL 1-3, Vol. 4684 (pp 1807-1818)
- Validation of volume-preserving non-rigid registration: Application to contrast-enhanced MR-mammography. MEDICAL IMAGE COMPUTING AND COMPUTER-ASSISTED INTERVENTION-MICCAI 2002, PT 1, Vol. 2488 (pp 307-314)
- Finite element based validation of non-rigid registration using single- and multi-level free-form deformations: Application to contrast-enhanced MR mammography. MEDICAL IMAGING 2002: IMAGE PROCESSING, VOL 1-3, Vol. 4684 (pp 550-561)
- Validation of Non-rigid Registration Using Finite Element Methods.. IPMI, Vol. 2082 (pp 344-357)
- Constructing Patient Specific Models for Correcting Intraoperative Brain Deformation.. MICCAI, Vol. 2208 (pp 1091-1098)
- A method for the comparison of biomechanical breast models. IEEE WORKSHOP ON MATHEMATICAL METHODS IN BIOMEDICAL IMAGE ANALYSIS, PROCEEDINGS (pp 11-18)
- Vortex shedding observations using magnetic resonance imaging, flow visualisation and computational fluid dynamics. COMPUTATIONAL METHODS AND EXPERIMENTAL MEASUREMENTS IX (pp 223-230)
- Kinematic and stress analysis of metacarpophalangeal joint implants. COMPUTER METHODS IN BIOMECHANICS & BIOMEDICAL ENGINEERING - 2 (pp 439-446)
- Cricket ball swing: A preliminary analysis using computational fluid dynamics. ENGINEERING OF SPORT (pp 11-19)
Reports
- In silico Clinical Trials: How Computer Simulations Will Transform the Biomedical Industry. An International Roadmap for an Industry-Driven Initiative.
Website content
- Home Page.
- Virtual Coronary Intervention. A Treatment Planning Tool Based Upon the Angiogram. JACC: Cardiovascular Imaging, 12(5), 865-872. View this article in WRRO