Professor Phillip Wright
BE (Hons), ME (Hons), PhD, FIChemE, CEng
Head of Department
Director of Research
Director of ChELSI Institute
Tel: +44 (0)114 222 7577
Fax: +44 (0)114 222 7501
Personal Assistant: Lucy Machin
Tel: +44 (0)114 222 7557
Fax: +44 (0)114 222 7566
email : l.machin@sheffield.ac.uk
Chemical and Biological Engineering
The University of Sheffield
Sir Robert Hadfield Building
Mappin Street
Sheffield
S1 3JD
Research Interests
- Research Interests 1: Systems Biology
- Synthetic Biology
- Metabolic Engineering
- Proteomics
- Biotechnology
Biography
I started my Chemical Engineering career as a cadet at BHP Steel in Wollongong NSW Australia, and completed my BE in Chemical Engineering by a combination of both full and part time study, graduating from the University of NSW in 1991.
I returned to BHP Steel as a Process Engineer for the years 1991-1993. During this period I also completed a part-time Research Master of Engineering (ME) in Mechanical Engineering with A/Prof WeeKing Soh, at the University of Wollongong, on mass transfer in novel contacting systems for biological applications.
I then returned to The University of NSW to undertake a PhD on three-phase fluidized bed bioreactors with Professor Judy Raper.
Upon completing my PhD in 1997 I took up the post of Lecturer, and later Reader, in Chemical Engineering at Heriot-Watt University. In 2001 I received an EPSRC Advanced Research Fellowship. In 2002 I took up my Chair in Systems Biology and Engineering at the University of Sheffield.
I am a Fellow of the Institution of Chemical Engineers. I took up the role of the Department's Director of Research in August 2004, Director of the ChELSI Institute in 2009 and became Head of Department in June 2008.
Key Papers
Wells MA, Mercer J, Mott RA, Pereira-Medrano AG, Burja AM, Radianingtyas H, Wright PC., Engineering a non-native hydrogen production pathway into Escherichia coli via a cyanobacterial [NiFe] hydrogenase, Metab Eng. 2011 Jan 27. [Epub ahead of print]
Pandhal J, Ow SY, Noirel J, Wright PC., Improving N-glycosylation efficiency in Escherichia coli using shotgun proteomics, metabolic network analysis, and selective reaction monitoring, Biotechnol Bioeng., 108(4), 2011, 902-12
Pham, T.K., Sierocinski, P., van der Oost J. and Wright, P.C., Quantitative proteomic analysis of Sulfolobus solfataricus membrane proteins, J Proteome Res., 9(2), 2010, 1165-1172
Noirel, J., Ow, S.Y., Sanguinetti G. and P.C. Wright, P.C., Systems biology meets synthetic biology: A case study of metabolic effects of synthetic rewiring, Mol. Biosyst., 2009, 5, 1214 - 1223
Ow, S.Y., Salim, M., Noirel, J., Evans, C., Rehman, I. and Wright, P.C., iTRAQ underestimation in simple and complex mixtures: “The good, the bad and the ugly”, J Proteome Res, 8(11), 2009, 5347-5355
Teaching
- CPE3003 - Advanced Reaction Engineering
- CPE6023 - Synthetic Biology