Professor Nigel Hoggard

MD, MRCP, FRCR

Clinical Medicine, School of Medicine and Population Health

Professor of Neuroradiology

n.hoggard@sheffield.ac.uk
+44 114 215 9607

+44 114 271 1714 (fax)

Floor C, Royal Hallamshire Hospital

Full contact details

Professor Nigel Hoggard
Clinical Medicine, School of Medicine and Population Health
Floor C
Royal Hallamshire Hospital
Glossop Road
Sheffield
S10 2JF

Profile

For enquiries please contact - ClinMed-Operational@sheffield.ac.uk

I joined the University of Sheffield in 2006 with interests in adult diagnostic neuroradiology and novel MR imaging agents. Prior to that I had been an NHS Consultant Neuroradiologist at the Manchester Neurosciences Centre, Hope Hospital Salford from 2003. I have been Professor of Neuroradiology since 2018.

I have published over 90 peer reviewed articles.

Research interests

My research interests remain primarily centred on the diagnostic applications of MR imaging in radiology with a particular emphasis on neuroscience and the cerebellum in particular. I work closely with Prof Marios Hadjivassiliou, we are part of the SIGReD group founded by Marios, a multi-disciplinary research group focussed on gluten related diseases. We have published numerous articles on gluten ataxia and brain imaging in gluten sensitivity.

The cerebellum is a small part of the brain that never the less contains over half of the neurons. It represents a highly compact system for combining and analysing information subconsciously for the rest of the brain, it can be thought of as the brain’s own supercomputer. It is designed to compare feedback information such as where is my hand in space to pre-existing models held in the cerebellum and then feed-forward into motor commands to ensure movements coordinated in real time such as would be required for catching a ball.The cerebellum not only helps the brain to control balance and coordination of movement but is now having its role in control of emotion, language and cognition gradually revealed. When it is damaged patients may be affected by falls and feel clumsy. They may lose the ability to walk, speak normally, use utensils or dress themselves and quite frequently may have to use a wheel chair as it becomes more severe.

The cerebellum is affected by a wide range of diseases including genetic conditions, degenerative conditions, alcohol and auto-immunity related diseases. There are new treatments being developed for diseases affecting the cerebellum but trials are hampered by the lack of suitable ways to measure their effectiveness. In dementia and MS many trial outcomes are based on MR imaging techniques as a well as clinical changes in the patients. But because the cerebellum’s activity is subconscious and represents feedback control beneath the surface it is difficult to measure clinically. Our group’s research is focussed on assessment of the cerebellum with advanced MR imaging based techniques. In particular, there is a need for measurements in the autoimmune cerebellar diseases and aggressive degenerative cerebellar disease such as MSA-C.

Gluten sensitivity, as well as causing ataxia, can be associated with accelerated white matter small vessel disease and imaging to assess this and the evaluation the blood brain barrier is an area of great interest to us in SIGReD. We recently published a paper demonstrating cognitive and structural brain changes in patients with coeliac ideas from the UK BioBank study in Gastroenterology. We have been recently funded by the Peter Sowerby Foundation to investigate the potential consequences of gluten possessing antibodies gliadins in the blood, which affects about 10% of the UK population, on brain structure and neuro-cognitive performance.

I have been heavily involved in the UK and European response to the evidence of the accumulation of gadolinium in the brain in patients after routine administration of gadolinium based contrast agents for MR scans.I co-chaired the PRAC which recommended to the Human Medicines agency to restrict the use of linear structure gadolinium based contrast agents in the European Union.

Publications

Show: Featured publications All publications

Featured publications

Journal articles

Croall ID, Sanders DS, Hadjivassiliou M & Hoggard N (2020) Cognitive deficit and white matter changes in persons with celiac disease: a population-based study. Gastroenterology. View this article in WRRO
Hadjivassiliou M, Martindale J, Shanmugarajah P, Grünewald RA, Sarrigiannis PG, Beauchamp N, Garrard K, Warburton R, Sanders DS, Friend D , Duty S et al (2016) Causes of progressive cerebellar ataxia: prospective evaluation of 1500 patients.. Journal of Neurology, Neurosurgery, and Psychiatry, 88, 301-309.
Hoggard N & Roditi GH (2016) T1 hyperintensity on brain imaging subsequent to gadolinium-based contrast agent administration: what do we know about intracranial gadolinium deposition?. British Journal of Radiology, 90(1069).
Raftopoulos R, Hickman SJ, Toosy A, Sharrack B, Mallik S, Paling D, Altmann DR, Yiannakas MC, Malladi P, Sheridan R , Sarrigiannis PG et al (2016) Phenytoin for neuroprotection in patients with acute optic neuritis: a randomised, placebo-controlled, phase 2 trial. The Lancet Neurology, 15(3), 259-269.
Currie S, Hadjivassiliou M, Wilkinson ID, Griffiths PD & Hoggard N (2013) Magnetic resonance spectroscopy of the normal cerebellum: what degree of variability can be expected?. Cerebellum, 12(2), 205-211.
Leeds JS, Hopper AD, Sidhu R, Simmonette A, Azadbakht N, Hoggard N, Morley S & Sanders DS (2010) Some patients with irritable bowel syndrome may have exocrine pancreatic insufficiency.. Clin Gastroenterol Hepatol, 8(5), 433-438.
Hoggard N, Darwent G, Capener D, Wilkinson ID & Griffiths PD (2009) The high incidence and bioethics of findings on magnetic resonance brain imaging of normal volunteers for neuroscience research.. J Med Ethics, 35(3), 194-199.

All publications

Journal articles

Floare M-L, Wharton SB, Simpson JE, Aeschlimann D, Hoggard N & Hadjivassiliou M (2024) Cerebellar degeneration in gluten ataxia is linked to microglial activation. Brain Communications, 6(2). View this article in WRRO
Croall ID, Aziz I, Trott N, Tosi P, Hoggard N & Sanders DS (2024) Retraction notice to “Gluten Does Not Induce Gastrointestinal Symptoms in Healthy Volunteers: A Double-Blind Randomized Placebo Trial” Gastroenterology 2019;157:881-883. Gastroenterology.
Maiter A, Hocking K, Matthews S, Taylor J, Sharkey M, Metherall P, Alabed S, Dwivedi K, Shahin Y, Anderson E , Holt S et al (2023) Evaluating the performance of artificial intelligence software for lung nodule detection on chest radiographs in a retrospective real-world UK population. BMJ Open, 13(11), e077348-e077348.
Ma Y-J, Moazamian D, Port JD, Edjlali M, Pruvo J-P, Hacein-Bey L, Hoggard N, Paley MNJ, Menon DK, Bonekamp D , Pravatà E et al (2023) Targeted magnetic resonance imaging (tMRI) of small changes in the T1 and spatial properties of normal or near normal appearing white and gray matter in disease of the brain using divided subtracted inversion recovery (dSIR) and divided reverse subtracted inversion recovery (drSIR) sequences. Quantitative Imaging in Medicine and Surgery, 13(10), 7304-7337.
Kon FC, Akil M, Kilding R, Kuet K-P, Shanmugarajah P, Hoggard N & Hadjivassiliou M (2022) P235 Cerebellar ataxia in primary Sjogren’s syndrome: is gluten sensitivity the answer?. Rheumatology, 61(Supplement_1).
Sassani M, Alix J, Mcdermott C, Baster K, Hoggard N, Wild J, Mortiboys H, Shaw P, Wilkinson I & Jenkins T (2021) Brain energy metabolism in ALS: A phosphorus-31 magnetic resonance spectroscopy study. Journal of the Neurological Sciences, 429, 119412-119412. View this article in WRRO
Mubarak Mohamed AS, Iqbal A, Prasad S, Hoggard N & Blackburn D (2021) Cushing’s disease presenting with psychosis. Practical Neurology, 21(4), 351-353.
Newrick L, Hoggard N & Hadjivassiliou M (2021) Recognition and management of rapid-onset gluten ataxias: case series.. Cerebellum Ataxias, 8(1), 16.
Kular S, Griffin K, Batty R, Hoggard N & Connolly D (2021) The role of MRI and CT of the brain in first episodes of psychosis and behavioural abnormality. Clinical Radiology.
Mahatma MM, Jayasuriya RL, Hughes D, Hoggard N, Buckley SC, Gordon A, Hamer AJ, Tomouk MW, Kerry RM, Eastell R & Wilkinson JM (2021) Denosumab after total hip arthroplasty – Authors' reply. The Lancet Rheumatology, 3(6), e406-e407.
Hadjivassiliou M, Croall ID, Grünewald RA, Trott N, Sanders DS & Hoggard N (2021) Neurological Evaluation of Patients with Newly Diagnosed Coeliac Disease Presenting to Gastroenterologists: A 7-Year Follow-Up Study.. Nutrients, 13(6).
Hadjivassiliou M, Zis P, Sanders DS, Hoggard N & Sarrigiannis PG (2021) Stiff person syndrome and gluten sensitivity. Nutrients, 13(4).
Croall ID, Hoggard N & Hadjivassiliou M (2021) Gluten and autism spectrum disorder. Nutrients, 13(2), 1-19.
Islam M, Hoggard N & Hadjivassiliou M (2021) Cerebrotendinous Xanthomatosis: diversity of presentation and refining treatment with chenodeoxycholic acid. Cerebellum and Ataxias, 8(1).
Mahatma MM, Jayasuriya RL, Hughes D, Hoggard N, Buckley SC, Gordon A, Hamer AJ, Tomouk MW, Kerry RM, Eastell R & Wilkinson JM (2021) Effect of denosumab on osteolytic lesion activity after total hip arthroplasty: a single-centre, randomised, double-blind, placebo-controlled, proof of concept trial. The Lancet Rheumatology.
Payne T, Sassani M, Buckley E, Moll S, Anton A, Appleby M, Maru S, Taylor R, McNeill A, Hoggard N , Mazza C et al (2020) Ursodeoxycholic acid as a novel disease-modifying treatment for Parkinson’s disease: protocol for a two-centre, randomised, double-blind, placebo-controlled trial, The 'UP' study. BMJ Open, 10(8), e038911-e038911.
Croall ID, Tooth C, Venneri A, Poyser C, Sanders DS, Hoggard N & Hadjivassiliou M (2020) Cognitive impairment in coeliac disease with respect to disease duration and gluten-free diet adherence : a pilot study. Nutrients, 12(7). View this article in WRRO
Barik SK, Dehury B, Russell WR, Moar KM, Cruickshank M, Scobbie L & Hoggard N (2020) Analysis of polyphenolic metabolites from in vitro gastrointestinal digested soft fruit extracts identify malvidin-3-glucoside as an inhibitor of PTP1B. Biochemical Pharmacology, 178, 114109-114109.
Croall ID, Sanders DS, Hadjivassiliou M & Hoggard N (2020) Cognitive deficit and white matter changes in persons with celiac disease: a population-based study. Gastroenterology. View this article in WRRO
Považan M, Mikkelsen M, Berrington A, Bhattacharyya PK, Brix MK, Buur PF, Cecil KM, Chan KL, Chen DYT, Craven AR , Cuypers K et al (2020) Comparison of Multivendor Single-Voxel MR Spectroscopy Data Acquired in Healthy Brain at 26 Sites. Radiology, 295(1), 171-180.
Arthurs OJ, Goh V, Hoggard N, Booth T, Messiou C, The J, Plumb A, Bidaut L, Turmezei T, Jethwa K , Robinson P et al (2020) Professional development and research are being neglected: a commentary on the 2019 RCR radiologists' supporting professional activities (SPA) survey. Clinical Radiology, 75(5), 348-350.
Jenkins TM, Alix JJP, Fingret J, Esmail T, Hoggard N, Baster K, McDermott CJ, Wilkinson ID & Shaw PJ (2020) Correction to: Longitudinal multi-modal muscle-based biomarker assessment in motor neuron disease. Journal of Neurology, 267(1), 257-258.
Alnajjar M, Kumar Barik S, Bestwick C, Campbell F, Cruickshank M, Farquharson F, Holtrop G, Horgan G, Louis P, Moar K-M , Russell WR et al (2020) Anthocyanin-enriched bilberry extract attenuates glycaemic response in overweight volunteers without changes in insulin. Journal of Functional Foods, 64, 103597-103597.
Barik SK, Russell WR, Moar KM, Cruickshank M, Scobbie L, Duncan G & Hoggard N (2020) The anthocyanins in black currants regulate postprandial hyperglycaemia primarily by inhibiting α-glucosidase while other phenolics modulate salivary α-amylase, glucose uptake and sugar transporters. The Journal of Nutritional Biochemistry, 78, 108325-108325.
Kadodwala VH, Hadjivassiliou M, Currie S, Skipper N & Hoggard N (2019) Is 1H-MR spectroscopy useful as a diagnostic aid in MSA-C?. Cerebellum & Ataxias, 6(1).
Sarrigiannis PG, Zis P, Unwin ZC, Blackburn DJ, Hoggard N, Zhao Y, Billings SA, Khan AA, Yianni J & Hadjivassiliou M (2019) Tremor after long term lithium treatment; is it cortical myoclonus?. Cerebellum & Ataxias, 6(5). View this article in WRRO
Croall I, Trott N, Rej A, Aziz I, O'Brien D, George H, Hossain M, Marks L, Richardson J, Rigby R , Hadjivassiliou M et al (2019) A population survey of dietary attitudes towards gluten. Nutrients, 11(6). View this article in WRRO
Croall I, Aziz I, Trott N, Paola T, Hoggard N, Sanders D, Rej A & Hadjivassiliou M (2019) Gluten does not induce gastrointestinal symptoms in healthy volunteers; A double blind randomised placebo trial. Gastroenterology. View this article in WRRO
Mikkelsen M, Rimbault DL, Barker PB, Bhattacharyya PK, Brix MK, Buur PF, Cecil KM, Chan KL, Chen DY-T, Craven AR , Cuypers K et al (2019) Big GABA II: Water-referenced edited MR spectroscopy at 25 research sites. NeuroImage, 191, 537-548. View this article in WRRO
Hadjivassiliou M, Croall ID, Zis P, Sarrigiannis PG, Sanders DS, Aeschlimann P, Grünewald RA, Armitage PA, Connolly D, Aeschlimann D & Hoggard N (2019) Neurologic Deficits in Patients With Newly Diagnosed Celiac Disease are Frequent and Linked With Autoimmunity to TG6. Clinical Gastroenterology and Hepatology. View this article in WRRO
Rao MR, Norquay G, Stewart N, Hoggard N, Griffiths P & Wild J (2019) Assessment of brain perfusion using hyperpolarized 129Xe MRI in a subject with established stroke.. Journal of Magnetic Resonance Imaging. View this article in WRRO
Goh V, Smye SW, Allen L, Ashcroft J, Cooper M, Gilbert FJ, Goh V, Graham R, Keevil S, Matthews J , Mould A et al (2019) The National Institute for Health Research: making an impact in imaging research. Clinical Radiology, 74(3), 242-246.
(2018) Novel genotype-phenotype and MRI correlations in a large cohort of patients with SPG7 mutations. Neurology Genetics, 4(6), e300-e300.
Hewamadduma CA, Hoggard N, O'Malley R, Robinson MK, Beauchamp NJ, Segamogaite R, Martindale J, Rodgers T, Rao G, Sarrigiannis P , Shanmugarajah P et al (2018) Novel genotype-phenotype and MRI correlations in a large cohort of patients with SPG7 mutations. Neurology Genetics, 4(6), e279-e279. View this article in WRRO
Sergi D, Campbell FM, Grant C, Morris AC, Bachmair E-M, Koch C, McLean FH, Muller A, Hoggard N, de Roos B , Porteiro B et al (2018) SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice. Genes & Nutrition, 13(1).
Smith R, Hadjivassiliou M, Hoggard N, Kuet K-P, Kilding R & Akil M (2018) An unusual case of inflammatory meningitis in a young man with systemic lupus erythematosus.. Lupus. View this article in WRRO
Mcsweeney M, Reuber M, Hoggard N & Levita L (2018) Cortical thickness and gyrification patterns in patients with psychogenic non-epileptic seizures. Neuroscience Letters, 678(Epilepsia 54 2013), 124-130. View this article in WRRO
Dimitriadis PA, Saad M, Igra MS, Mandavia R, Bowes C, Hoggard N & Ray J (2018) White matter lesions in magnetic resonance imaging of the brain in 56 patients with visual vertigo. The Journal of Laryngology & Otology, 132(06), 550-553.
Blackburn DJ, Forbes M, Unwin Z, Hoggard N, Hadjivassiliou M & Sarrigiannis PG (2018) Exaggerated startle in post-infectious opsoclonus myoclonus syndrome. Clinical Neurophysiology, 129(7), 1372-1373. View this article in WRRO
Rees D, Holtrop G, Chope G, Moar KM, Cruickshank M & Hoggard N (2018) A randomised, double-blind, cross-over trial to evaluate bread, in which gluten has been pre-digested by prolyl endoprotease treatment, in subjects self-reporting benefits of adopting a gluten-free or low-gluten diet. British Journal of Nutrition, 119(5), 496-506.
Pierry IA, Alix JJP, Rao DG, Hoggard N, Bigley J, McDermott CJ, Wilkinson ID, Shaw PJ & Jenkins TM (2018) Longitudinal Diffusion-Weighted Whole-Body MRI Demonstrates Dynamic Changes in Muscle Integrity in Motor Neuron Disease. Journal of Neuromuscular Diseases, 5(1), 107-107.
Jenkins T, Alix J, David C, Pearson E, Ganesh Rao D, Hoggard N, O'Brien E, Baster K, Bradburn M, Bigley J , McDermott C et al (2018) Imaging muscle as a potential biomarker of denervation in motor neuron disease. Journal of Neurology, Neurosurgery, and Psychiatry, 89, 248-255. View this article in WRRO
Shanmugarajah PD, Hoggard N, Aeschlimann DP, Aeschlimann PC, Dennis GJ, Howell SJ, Reuber M, Grünewald RA & Hadjivassiliou M (2018) Phenytoin-related ataxia in patients with epilepsy: clinical and radiological characteristics. Seizure, 56, 26-30.
Larsen J, Hoggard N & McKevitt FM (2018) Imaging in low-grade glioma: a guide for neurologists.. Pract Neurol, 18(1), 27-34.
Zis P, Rao DG, Hoggard N, Sarrigiannis PG & Hadjivassiliou M (2017) Anti-MAG associated cerebellar ataxia and response to rituximab.. J Neurol.
Ng YS, Powell H, Hoggard N, Turnbull DM, Taylor RW & Hadjivassiliou M (2017) Novel POLG variants associated with late-onset de novo status epilepticus and progressive ataxia. Neurology Genetics, 3(5), e181-e181. View this article in WRRO
Mikkelsen M, Barker PB, Bhattacharyya PK, Brix MK, Buur PF, Cecil KM, Chan KL, Chen DY-T, Craven AR, Cuypers K , Dacko M et al (2017) Big GABA: Edited MR spectroscopy at 24 research sites. NeuroImage, 159, 32-45. View this article in WRRO
Mehmood S, Hoggard N & Hadjivassiliou M (2017) Gordon Holmes syndrome: finally genotype meets phenotype.. Pract Neurol.
Hadjivassiliou M, Grünewald RA, Sanders DS, Shanmugarajah P & Hoggard N (2017) Effect of gluten-free diet on cerebellar MR spectroscopy in gluten ataxia.. Neurology, 89(7), 705-709.
Igra MS, Paling D, Wattjes MP, Connolly DJ & Hoggard N (2017) Multiple sclerosis update: use of MRI for early diagnosis, disease monitoring and assessment of treatment related complications. British Journal of Radiology, 90(1074).
Zis P, Rao DG, Wagner BE, Nicholson-Goult L, Hoggard N & Hadjivassiliou M (2017) Cerebellar ataxia and sensory ganglionopathy associated with light-chain myeloma.. Cerebellum Ataxias, 4, 1-1. View this article in WRRO
Zis P, Sarrigiannis PG, Rao DG, Hoggard N, Sanders DS & Hadjivassiliou M (2017) Cerebellar ataxia with sensory ganglionopathy; does autoimmunity have a role to play?. Cerebellum & Ataxias, 4(1). View this article in WRRO
Hadjivassiliou M, Martindale J, Shanmugarajah P, Grünewald RA, Sarrigiannis PG, Beauchamp N, Garrard K, Warburton R, Sanders DS, Friend D , Duty S et al (2016) Causes of progressive cerebellar ataxia: prospective evaluation of 1500 patients.. Journal of Neurology, Neurosurgery, and Psychiatry, 88, 301-309.
Larsen J, Wharton SB, Romanowski C, McKevitt FM, Bridgewater C, Zaki H & Hoggard N (2016) Low grade glioma: An Update for Radiologists.. British Journal of Radiology. View this article in WRRO
Hoggard N & Roditi GH (2016) T1 hyperintensity on brain imaging subsequent to gadolinium-based contrast agent administration: what do we know about intracranial gadolinium deposition?. British Journal of Radiology, 90(1069).
Shanmugarajah PD, Hoggard N, Currie S, Aeschlimann DP, Aeschlimann PC, Gleeson DC, Karajeh M, Woodroofe N, Grünewald RA & Hadjivassiliou M (2016) Alcohol-related cerebellar degeneration: not all down to toxicity?. Cerebellum Ataxias, 3, 17-17. View this article in WRRO
Penny HA, Aziz I, Ferrar M, Atkinson J, Hoggard N, Hadjivassiliou M, West JN & Sanders DS (2016) Is there a relationship between gluten sensitivity and postural tachycardia syndrome?. European Journal of Gastroenterology & Hepatology, 28(12), 1383-1387.
He F, Sarrigiannis PG, Billings SA, Wei H, Rowe J, Romanowski C, Hoggard N, Hadjivassilliou M, Rao DG, Grünewald R , Khan A et al (2016) Nonlinear interactions in the thalamocortical loop in essential tremor: A model-based frequency domain analysis. Neuroscience, 324, 377-389. View this article in WRRO
Hadjivassiliou M, Rao DG, Grìnewald RA, Aeschlimann DP, Sarrigiannis PG, Hoggard N, Aeschlimann P, Mooney PD & Sanders DS (2016) Neurological Dysfunction in Coeliac Disease and Non-Coeliac Gluten Sensitivity. The American Journal of Gastroenterology, 111(4), 561-567. View this article in WRRO
Raftopoulos R, Hickman SJ, Toosy A, Sharrack B, Mallik S, Paling D, Altmann DR, Yiannakas MC, Malladi P, Sheridan R , Sarrigiannis PG et al (2016) Phenytoin for neuroprotection in patients with acute optic neuritis: a randomised, placebo-controlled, phase 2 trial. The Lancet Neurology, 15(3), 259-269.
Stivaros SM, Radon MR, Mileva R, Connolly DJA, Cowell PE, Hoggard N, Wright NB, Tang V, Gledson A, Batty R , Keane JA et al (2016) Quantification of structural changes in the corpus callosumin children with profound hypoxic–ischaemic brain injury. Pediatric Radiology, 46(1), 73-81. View this article in WRRO
Baldarçara L, Currie S, Hadjivassiliou M, Hoggard N, Jack A, Jackowski AP, Mascalchi M, Parazzini C, Reetz K, Righini A , Schulz JB et al (2015) Consensus Paper: Radiological Biomarkers of Cerebellar Diseases. The Cerebellum, 14(2), 175-196. View this article in WRRO
Sandler RD, Hoggard N & Hadjivassiliou M (2015) Miller-Fisher Syndrome: Is the ataxia central or peripheral?. Cerebellum & Ataxias, 2(1). View this article in WRRO
Sarrigiannis PG, Zhao Y, He F, Wei H, Billings SA, Lawrence S, Rowe J, Romanowski C, Hoggard N, Rao DG , Grünewald R et al (2015) Direct Functional Connectivity between the Thalamus (Vim) and the Contralateral Motor Cortex: Just a Single Case Observation or a Common Pathway in the Human Brain?. Brain Stimulation, 8(6), 1230-1233.
Sarrigiannis P, Hoggard N, Aeschlimann D, Sanders D, Grunewald R, Unwin Z & Hadjivassiliou M (2014) Myoclonus ataxia and refractory coeliac disease. Cerebellum & Ataxias, 1. View this article in WRRO
Clark MJ, Prentice JR, Hoggard N, Paley MN, Hadjivassiliou M & Wilkinson JM (2014) Brain structure and function in patients after metal-on-metal hip resurfacing.. AJNR Am J Neuroradiol, 35(9), 1753-1758.
Stenberg R, Hadjivassiliou M, Aeschlimann P, Hoggard N & Aeschlimann D (2014) Anti-transglutaminase 6 antibodies in children and young adults with cerebral palsy.. Autoimmune Dis, 2014, 237107. View this article in WRRO
Bradley D & Hoggard N (2014) Happy new year from BJR!. British Journal of Radiology, 87(1033).
Kheder A, Hoggard N & Hickman SJ (2014) Neurological red flag: the numb chin.. Pract Neurol, 14(4), 258-260.
Janaway BM, Simpson JE, Hoggard N, Highley JR, Forster G, Drew D, Gebril OH, Matthews FE, Brayne C, Wharton SB , Ince PG et al (2014) Brain haemosiderin in older people: pathological evidence for an ischaemic origin of magnetic resonance imaging (MRI) microbleeds.. Neuropathol Appl Neurobiol, 40(3), 258-269. View this article in WRRO
Shanmugarajah P, Hoggard N, Howell S, Dennis G, Reuber M, Grunewald R & Hadjivassiliou M (2013) PHENYTOIN AND CEREBELLAR ATAXIA: NOT ALL DOWN TO TOXICITY?. J Neurol Neurosurg Psychiatry, 84(11), e2.
Hadjivassiliou M, Fotheringham J, Sanders D, Grunewald R, Hoggard N & Sarrigiannis P (2013) HYPEREXCITABLE BRAIN AND REFRACTORY COELIAC DISEASE: A NEW SYNDROME.. J Neurol Neurosurg Psychiatry, 84(11), e2.
Currie S, Hoggard N, Clark MJR, Sanders DS, Wilkinson ID, Griffiths PD & Hadjivassiliou M (2013) Alcohol Induces Sensitization to Gluten in Genetically Susceptible Individuals: A Case Control Study. PLoS ONE, 8(10). View this article in WRRO
Hoggard N, Cruickshank M, Moar K-M, Bestwick C, Holst JJ, Russell W & Horgan G (2013) A single supplement of a standardised bilberry (Vaccinium myrtillus L.) extract (36 % wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes controlled by diet and lifestyle. Journal of Nutritional Science, 2.
Jenkins TM, Burness C, Connolly DJ, Rao DG, Hoggard N, Mawson S, McDermott CJ, Wilkinson ID & Shaw PJ (2013) A prospective pilot study measuring muscle volumetric change in amyotrophic lateral sclerosis.. Amyotroph Lateral Scler Frontotemporal Degener, 14(5-6), 414-423. View this article in WRRO
Blackburn DJ, Alix JJP, Sarrigiannis P, Hoggard N & Bandmann O (2013) Delayed toxic-hypoxic encephalopathy.. Pract Neurol, 13(2), 114-119.
Blackburn D, Randall MS, Hoggard N, Highley R & Harkness K (2013) Trigeminal neuralgia: no laughing matter.. Pract Neurol, 13(4), 263-267.
Goode SD, Hoggard N, Macdonald S, Evans DH, Cleveland TJ & Gaines PA (2013) Assessment of reverse flow as a means of cerebral protection during carotid artery stent placement with diffusion-weighted and transcranial Doppler imaging.. J Vasc Interv Radiol, 24(4), 528-533.
Hadjivassiliou M, Currie S & Hoggard N (2013) MR spectroscopy in paraneoplastic cerebellar degeneration.. J Neuroradiol, 40(4), 310-312.
Prentice JR, Clark MJ, Hoggard N, Morton AC, Tooth C, Paley MN, Stockley I, Hadjivassiliou M & Wilkinson JM (2013) Metal-on-metal hip prostheses and systemic health: a cross-sectional association study 8 years after implantation.. PLoS One, 8(6), e66186. View this article in WRRO
Khandanpour N, Griffiths P, Hoggard N & Warren D (2013) Prospective comparison of late 3T MRI with conventional angiography in evaluating the patency of cerebral arteriovenous malformations treated with stereotactic radiosurgery. Neuroradiology, 1-5.
Currie S, Hoggard N, Craven IJ, Hadjivassiliou M & Wilkinson ID (2013) Understanding MRI: basic MR physics for physicians.. Postgrad Med J, 89(1050), 209-223.
Currie S, Hadjivassiliou M, Craven IJ, Wilkinson ID, Griffiths PD & Hoggard N (2013) Magnetic resonance spectroscopy of the brain.. Postgrad Med J, 89(1048), 94-106.
Currie S, Hadjivassiliou M, Wilkinson ID, Griffiths PD & Hoggard N (2013) Magnetic resonance spectroscopy of the normal cerebellum: what degree of variability can be expected?. Cerebellum, 12(2), 205-211.
Khandanpour N, Hoggard N & Connolly DJA (2013) The role of MRI and CT of the brain in first episodes of psychosis.. Clin Radiol, 68(3), 245-250.
Koch CE, Ganjam GK, Steger J, Legler K, Stöhr S, Schumacher D, Hoggard N, Heldmaier G & Tups A (2013) The dietary flavonoids naringenin and quercetin acutely impair glucose metabolism in rodents possibly via inhibition of hypothalamic insulin signalling. British Journal of Nutrition, 109(6), 1040-1051.
Currie S, Hadjivassiliou M, Craven IJ, Wilkinson ID, Griffiths PD & Hoggard N (2013) Magnetic resonance imaging biomarkers in patients with progressive ataxia: current status and future direction.. Cerebellum, 12(2), 245-266.
Khandanpour N, Connolly DJA, Raghavan A, Griffiths PD & Hoggard N (2012) Craniospinal abnormalities and neurologic complications of osteogenesis imperfecta: imaging overview.. Radiographics, 32(7), 2101-2112.
Alix JJP, Ponnusamy A, Bhattacharyya D, Hoggard N & Grünewald RA (2012) Complex partial seizures: going out with a hiccup.. Seizure, 21(10), 820-822.
Hoggard N, Cruickshank M, Moar K-M, Bashir S & Mayer C-D (2012) Using Gene Expression to Predict Differences in the Secretome of Human Omental vs. Subcutaneous Adipose Tissue. Obesity, 20(6), 1158-1167.
Currie S, Hadjivassiliou M, Clark MJR, Sanders DS, Wilkinson ID, Griffiths PD & Hoggard N (2012) Should we be 'nervous' about coeliac disease? Brain abnormalities in patients with coeliac disease referred for neurological opinion.. J Neurol Neurosurg Psychiatry, 83(12), 1216-1221.
Yianni J, Rowe J, Khandanpour N, Nagy G, Hoggard N, Radatz M & Kemeny A (2012) Stereotactic radiosurgery for pineal tumours.. Br J Neurosurg, 26(3), 361-366.
Craven IJ, Griffiths PD, Bhattacharyya D, Grunewald RA, Hodgson T, Connolly DJA, Coley SC, Batty R, Romanowski CAJ & Hoggard N (2012) 3.0 T MRI of 2000 consecutive patients with localisation-related epilepsy.. Br J Radiol, 85(1017), 1236-1242.
Hadjivassiliou M, Wallis LI, Hoggard N, Grünewald RA, Griffiths PD & Wilkinson ID (2012) MR spectroscopy and atrophy in Gluten, Friedreich's and SCA6 ataxias.. Acta Neurol Scand, 126(2), 138-143.
Kotsarini C, Wilkinson ID, Jellinek D, Griffiths PD, Khandanpour N & Hoggard N (2011) USE OF MR SPECTROSCOPY AND DIFFUSION TO DIFFERENTIATE GBM FROM SOLITARY CEREBRAL METASTASES. NEURO-ONCOLOGY, 13, 141-141.
Kotsarini C, Wilkinson ID, Jellinek D, Griffiths PD, Bambrough P & Hoggard N (2011) CHO/CR RATIO APPEARS TO BE AN INDEPENDENT IMAGING BIOMARKER OF SURVIVAL FOR PATIENTS NOT SUITABLE FOR OPEN RESECTION OF GLIOBLASTOMA. NEURO-ONCOLOGY, 13, 141-142.
Blackburn D, Chavada G, Dunleavy D, Hoggard N, Sharrack B, Ponnusamy S & Price S (2011) GUILLAIN-BARRE SYNDROME (GBS) PRESENTING WITH POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME. J NEUROL NEUROSUR PS, 82(9).
Padidar S, Farquharson AJ, Williams LM, Kelaiditi E, Hoggard N, Arthur JR & Drew JE (2011) Leptin up-regulates pro-inflammatory cytokines in discrete cells within mouse colon. Journal of Cellular Physiology, 226(8), 2123-2130.
Wilkinson VH, Carroll T & Hoggard N (2011) Contrasting natural histories of thoracic spine pneumatocysts: resolution versus rapid enlargement.. Br J Radiol, 84(1000), e79-e82.
Craven I, Griffiths PD & Hoggard N (2011) Magnetic resonance imaging of epilepsy at 3 Tesla. Clinical Radiology.
Padidar S, Farquharson AJ, Williams LM, Hoggard N, Reid MD, Duncan GJ & Drew JE (2011) Impact of Obesity and Leptin on Protein Expression Profiles in Mouse Colon. Digestive Diseases and Sciences, 56(4), 1028-1036.
Kotsarini C, Griffiths PD, Wilkinson ID & Hoggard N (2010) A systematic review of the literature on the effects of dexamethasone on the brain from in vivo human-based studies: implications for physiological brain imaging of patients with intracranial tumors.. Neurosurgery, 67(6), 1799-1815.
Craven I, Kotsarini C & Hoggard N (2010) Recent advances in imaging epilepsy.. Postgrad Med J, 86(1019), 552-559.
Warren DJ, Musson R, Connolly DJA, Griffiths PD & Hoggard N (2010) Imaging in acute ischaemic stroke: essential for modern stroke care.. Postgrad Med J, 86(1017), 409-418.
Boye T, Yousefpour A, Smith A & Hoggard N (2010) P15 A pictorial review of the role of CT angiography (CTA) in head and neck cancer imaging. British Journal of Oral and Maxillofacial Surgery, 48, S28-S28.
Leeds JS, Hopper AD, Sidhu R, Simmonette A, Azadbakht N, Hoggard N, Morley S & Sanders DS (2010) Some patients with irritable bowel syndrome may have exocrine pancreatic insufficiency.. Clin Gastroenterol Hepatol, 8(5), 433-438.
Wignall EL, Griffiths PD, Papadakis NG, Wilkinson ID, Wallis LI, Bandmann O, Cowell PEE & Hoggard N (2010) Corpus Callosum Morphology and Microstructure Assessed Using Structural MR Imaging and Diffusion Tensor Imaging: Initial Findings in Adults with Neurofibromatosis Type 1. AM J NEURORADIOL, 31(5), 856-861.
Bigley J, Griffiths PD, Prydderch A, Romanowski CAJ, Miles L, Lidiard H & Hoggard N (2010) Neurolinguistic programming used to reduce the need for anaesthesia in claustrophobic patients undergoing MRI.. Br J Radiol, 83(986), 113-117.
Gwilliam MN, Hoggard N, Capener D, Singh P, Marzo A, Verma PK & Wilkinson ID (2009) MR derived volumetric flow rate waveforms at locations within the common carotid, internal carotid, and basilar arteries.. J Cereb Blood Flow Metab, 29(12), 1975-1982.
Griffiths PD & Hoggard N (2009) Distribution and conspicuity of intracranial abnormalities on MR imaging in adults with tuberous sclerosis complex: A comparison of sequences including ultrafast T2-weighted images.. Epilepsia, 50(12), 2605-2610.
Woodhouse N, Wild JM, van Beek EJR, Hoggard N, Barker N & Taylor CJ (2009) Assessment of hyperpolarized 3He lung MRI for regional evaluation of interventional therapy: a pilot study in pediatric cystic fibrosis.. J Magn Reson Imaging, 30(5), 981-988.
Hoggard N, Cruickshank M, Moar KM, Barrett P, Bashir S & Miller JDB (2009) Inhibin βB expression in murine adipose tissue and its regulation by leptin, insulin and dexamethasone. Journal of Molecular Endocrinology, 43(4), 171-177.
Hoggard N (2009) Re: Development and initial testing of normal reference MR images for the brain at ages 65-70 and 75-80 years. EUR RADIOL, 19(4), 1025-1025.
Hoggard N, Darwent G, Capener D, Wilkinson ID & Griffiths PD (2009) The high incidence and bioethics of findings on magnetic resonance brain imaging of normal volunteers for neuroscience research.. J Med Ethics, 35(3), 194-199.
Ireland RH, Woodhouse N, Hoggard N, Swinscoe JA, Foran BH, Hatton MQ & Wild JM (2008) An image acquisition and registration strategy for the fusion of hyperpolarized helium-3 MRI and x-ray CT images of the lung.. Phys Med Biol, 53(21), 6055-6063.
Hoggard N, Wilkinson ID, Griffiths PD, Vaughan P, Kemeny AA & Rowe JG (2008) The clinical course after stereotactic radiosurgical amygdalohippocampectomy with neuroradiological correlates.. Neurosurgery, 62(2), 336-344.
Wilkinson ID, Hoggard N, Jellinek DA, Levy D, Kotsarini C, Batty R, Griffiths PD & Romanowski CAJ (2008) MR perfusion: Techniques used for intracranial tumour assessment. Neuroradiology Journal, 21(SUPPL. 1), 20-26.
Romanowski CAJ, Hoggard N, Jellinek DA, Levy D, Wharton SB, Kotsarini C, Batty R & Wilkinson ID (2008) Low grade gliomas. Can we predict tumour behaviour from imaging features?. Neuroradiology Journal, 21(SUPPL. 1), 47-66.
Haggerty C, Hoggard N, Brown DS, Clapham JC & Speakman JR (2008) Intra-specific variation in resting metabolic rate in MF1 mice is not associated with membrane lipid desaturation in the liver. Mechanisms of Ageing and Development, 129(3), 129-137.
Hoggard N, Bashir S, Cruickshank M, Miller JDB & Speakman JR (2007) Expression of neuromedin B in adipose tissue and its regulation by changes in energy balance. Journal of Molecular Endocrinology, 39(3), 199-210.
Warren DJ, Hoggard N, Walton L, Radatz MWR, Kemeny AA, Forster DMC, Wilkinson ID & Griffiths PD (2007) Cerebral arteriovenous malformations: comparison of novel magnetic resonance angiographic techniques and conventional catheter angiography.. Neurosurgery, 61(1 Suppl), 187-196.
Ireland RH, Dyker KE, Barber DC, Wood SM, Hanney MB, Tindale WB, Woodhouse N, Hoggard N, Conway J & Robinson MH (2007) Nonrigid image registration for head and neck cancer radiotherapy treatment planning with PET/CT.. Int J Radiat Oncol Biol Phys, 68(3), 952-957.
O’Connor DM, Blache D, Hoggard N, Brookes E, Wooding FBP, Fowden AL & Forhead AJ (2007) Developmental Control of Plasma Leptin and Adipose Leptin Messenger Ribonucleic Acid in the Ovine Fetus during Late Gestation: Role of Glucocorticoids and Thyroid Hormones. Endocrinology, 148(8), 3750-3757.
Griffiths PD, Pandya H, Wilkinson ID & Hoggard N (2006) Sequential dynamic gadolinium magnetic resonance perfusion-weighted imaging: effects on transit time and cerebral blood volume measurements.. Acta Radiol, 47(10), 1079-1084.
Hoggard N, Rayner DV, Johnston SL & Speakman JR (2004) Peripherally administered [Nle4,d-Phe7]-α-melanocyte stimulating hormone increases resting metabolic rate, while peripheral agouti-related protein has no effect, in wild type C57BL/6 and ob/ob mice. Journal of Molecular Endocrinology, 33(3), 693-703.
Hoggard N, Feasby TE, Kennedy J, Quan H & Ghali WA (2004) Importance of the imaging modality in decision making about carotid endarterectomy. Neurology, 63(7), 1340-1341.
Hoggard N, Johnstone AM, Faber P, Gibney ER, Elia M, Lobley G, Rayner V, Horgan G, Hunter L, Bashir S & Stubbs RJ (2004) Plasma concentrations of alpha-MSH, AgRP and leptin in lean and obese men and their relationship to differing states of energy balance perturbation. Clinical Endocrinology, 61(1), 31-39.
Hoggard N (2004) Conventional digital subtraction x-ray angiography versus magnetic resonance angiography in the evaluation of carotid disease: patient satisfaction and preferences.. Clin Radiol, 59(4), 356-357.
Hoggard N, Hunter L, Duncan JS & Rayner DV (2004) Regulation of adipose tissue leptin secretion by alpha-melanocyte-stimulating hormone and agouti-related protein: further evidence of an interaction between leptin and the melanocortin signalling system. Journal of Molecular Endocrinology, 32(1), 145-153.
Wilkinson ID, Griffiths PD, Hoggard N, Cleveland TJ, Gaines PA, Macdonald S, McKevitt F & Venables GS (2003) Short-term changes in cerebral microhemodynamics after carotid stenting.. AJNR Am J Neuroradiol, 24(8), 1501-1507.
Madlom MM, Hoggard N, Griffiths PD & Chan J (2003) Facial naevus flammeus with choroidal haemangioma and without intracranial involvement. DEV MED CHILD NEUROL, 45(2), 139-139.
Duttaroy AK, Taylor J, Gordon MJ, Hoggard N & Campbell FM (2002) Arachidonic acid stimulates internalisation of leptin by human placental choriocarcinoma (BeWo) cells. Biochemical and Biophysical Research Communications, 299(3), 432-437.
Hoggard N, Wilkinson ID, Paley MNI & Griffiths PD (2002) Imaging of haemorrhagic stroke.. Clin Radiol, 57(11), 957-968.
Forhead AJ, Thomas L, Crabtree J, Hoggard N, Gardner DS, Giussani DA & Fowden AL (2002) Plasma Leptin Concentration in Fetal Sheep during Late Gestation: Ontogeny and Effect of Glucocorticoids. Endocrinology, 143(4), 1166-1173.
ANTIPATIS C, ASHWORTH CJ, RILEY SC, HANNAH L, HOGGARD N & LEA RG (2002) Vitamin A Deficiency During Rat Pregnancy Alters Placental TNF-α Signalling and Apoptosis. American Journal of Reproductive Immunology, 47(3), 151-158.
Hoggard N, Paley MN, Whitby EH & Griffiths P (2001) Comparison of the aging of neonatal and adult blood samples in an in vitro subdural hemorrhage model. RADIOLOGY, 221, 487-487.
Griffiths PD, Wilkinson ID, Wels T & Hoggard N (2001) Brain MR perfusion imaging in humans - Advantages of high-molarity gadolinium chelates. ACTA RADIOL, 42(6), 555-559.
Griffiths PD, Wilkinson ID, Wels T & Hoggard N (2001) Brain MR perfusion imaging in humans.. Acta Radiol, 42(6), 555-559.
Griffiths PD, Wilkinson ID, Mitchell P, Patel MC, Paley MN, Romanowski CA, Powell T, Hodgson TJ, Hoggard N & Jellinek D (2001) Multimodality MR imaging depiction of hemodynamic changes and cerebral ischemia in subarachnoid hemorrhage.. AJNR Am J Neuroradiol, 22(9), 1690-1697.
Sanders DS, Carter MJ, Lobo AJ & Hoggard N (2001) Research outcomes in British gastroenterology: an audit of the subsequent full publication of abstracts presented at the British Society of Gastroenterology. GUT, 49(1), 154-155.
Graham JM, Paley MNJ, Grünewald RA, Hoggard N & Griffiths PD (2001) Erratum: Brain iron deposition in Parkinson's disease imaged using the PRIME magnetic resonance sequence (Brain (December 2000) 123:12 (2423-2431)). Brain, 124(6), 1258.
Thomas L, Wallace JM, Aitken RP, Mercer JG, Trayhurn P & Hoggard N (2001) Circulating leptin during ovine pregnancy in relation to maternal nutrition, body composition and pregnancy outcome. Journal of Endocrinology, 169(3), 465-476.
Warren DJ, Hoggard N, Walton L, Radatz MWR, Kemeny AA, Forster DMC, Wilkinson ID & Griffiths PD (2001) Cerebral Arteriovenous Malformations: Comparison of Novel Magnetic Resonance Angiographic Techniques and Conventional Catheter Angiography. Neurosurgery, 48(5), 973-983.
Warren DJ, Hoggard N, Walton L, Radatz MW, Kemeny AA, Forster DM, Wilkinson ID & Griffiths PD (2001) Cerebral arteriovenous malformations: comparison of novel magnetic resonance angiographic techniques and conventional catheter angiography.. Neurosurgery, 48(5), 973-982.
Hoggard N, Wilkinson ID & Griffiths PD (2001) The imaging of ischaemic stroke.. Clin Radiol, 56(3), 171-183.
Mitchell P, Wilkinson ID, Hoggard N, Paley MN, Jellinek DA, Powell T, Romanowski C, Hodgson T & Griffiths PD (2001) Detection of subarachnoid haemorrhage with magnetic resonance imaging.. J Neurol Neurosurg Psychiatry, 70(2), 205-211.
Dugar N, Hoggard N, Wilkinson ID & Griffiths PD (2001) MR imaging in acute stroke. Imaging Decisions MRI, 5(1), 2-10.
Griffiths PD, Hoggard N, Dannels WR & Wilkinson ID (2001) In vivo measurement of cerebral blood flow: a review of methods and applications.. Vasc Med, 6(1), 51-60.
Hoggard N, Crabtree J, Allstaff S, Abramovich DR & Haggarty P (2001) Leptin Secretion to Both the Maternal and Fetal Circulation in the Ex Vivo Perfused Human Term Placenta. Placenta, 22(4), 347-352.
Yamashita H, Shao J, Ishizuka T, Klepcyk PJ, Muhlenkamp P, Qiao L, Hoggard N & Friedman JE (2001) Leptin Administration Prevents Spontaneous Gestational Diabetes in Heterozygous Lepr^db/+Mice: Effects on Placental Leptin and Fetal Growth¹. Endocrinology, 142(7), 2888-2897.
Mercer JG, Hoggard N & Morgan PJ (2000) Leptin and Obesity. CNS Drugs, 14(6), 413-424.
Hoggard N, Hunter L, Lea RG, Trayhurn P & Mercer JG (2000) Ontogeny of the expression of leptin and its receptor in themurine fetus and placenta. British Journal of Nutrition, 83(3), 317-326.
Graham JM, Paley MN, Grünewald RA, Hoggard N & Griffiths PD (2000) Brain iron deposition in Parkinson's disease imaged using the PRIME magnetic resonance sequence.. Brain, 123 Pt 12, 2423-2431.
Griffiths PD, Hoggard N, Warren DJ, Wilkinson ID, Anderson B & Romanowski CA (2000) Brain arteriovenous malformations: assessment with dynamic MR digital subtraction angiography.. AJNR Am J Neuroradiol, 21(10), 1892-1899.
Bretschneider T & Strotzer M (2000) Leptomeningeal Enhancement and Extravasation of Contrast Medium into the CSF Space?. Stroke, 31(9), 2266-2278.
Lu C-J, Sun Y & Huang K-M (2000) Leptomeningeal Enhancement After Carotid Stenting. Stroke, 31(9), 2266-2278.
Wilkinson ID, Griffiths PD, Hoggard N, Cleveland TJ, Gaines PA & Venables GS (2000) Leptomeningeal enhancement and extravasation of contrast medium into the CSF space? Response. STROKE, 31(9), 2276-2277.
Lea RG, Howe D, Hannah LT, Bonneau O, Hunter L & Hoggard N (2000) Placental leptin in normal, diabetic and fetal growth-retarded pregnancies. Molecular Human Reproduction, 6(8), 763-769.
Sanders DS, Carter MJ, Hurlstone P, Hoggard N & Lobo AJ (2000) Full publication of abstracts presented at the British Society of Gastroenterology.. GASTROENTEROLOGY, 118(4), A217-A217.
Sanders DS, Carter MJ, Hurlstone JP, Hoggard N & Lobo AJ (2000) Full publication of abstracts presented at the British Society of Gastroenterology. GUT, 46, A18-A18.
Wilkinson ID, Griffiths PD, Hoggard N, Cleveland TJ, Gaines PA & Venables GS (2000) Unilateral leptomeningeal enhancement after carotid stent insertion detected by magnetic resonance imaging.. Stroke, 31(4), 848-851.
Ashworth C (2000) Placental leptin. Reviews of Reproduction, 5(1), 18-24.
Mercer JG, Moar KM, Ross AW, Hoggard N & Morgan PJ (2000) Photoperiod regulates arcuate nucleus POMC, AGRP, and leptin receptor mRNA in Siberian hamster hypothalamus. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 278(1), R271-R281.
Williams , Adam , Mercer , Moar , Slater , Hunter , Findlay & Hoggard (1999) Leptin Receptor and Neuropeptide Y Gene Expression in the Sheep Brain. Journal of Neuroendocrinology, 11(3), 165-169.
Trayhurn P, Hoggard N, Mercer JG & Rayner DV (1999) Leptin: fundamental aspects. International Journal of Obesity, 23(S1), S22-S28.
Trayhurn P, Hoggard N, Mercer JG & Rayner DV (1998) Hormonal and neuroendocrine regulation of energy balance‐the role of leptin. Archiv für Tierernaehrung, 51(2-3), 177-185.
Hoggard N, Hunter L, Trayhurn P, Williams LM & Mercer JG (1998) Leptin and reproduction. Proceedings of the Nutrition Society, 57(3), 421-427.
Trayhum P, Duncan JS, Hoggard N & Rayner DV (1998) Regulation of leptin production: a dominant role for the sympathetic nervous system?. Proceedings of the Nutrition Society, 57(3), 413-419.
Mercer JG, Moar KM, Findlay PA, Hoggard N & Adam CL (1998) Association of leptin receptor (OB-Rb), NPY and GLP-1 gene expression in the ovine and murine brainstem. Regulatory Peptides, 75-76, 271-278.
Campbell FM, Gordon MJ, Hoggard N & Dutta-Roy AK (1998) Interaction of Free Fatty Acids with Human Leptin. Biochemical and Biophysical Research Communications, 247(3), 654-658.
Mercer JG, Moar KM & Hoggard N (1998) Localization of Leptin Receptor (Ob-R) Messenger Ribonucleic Acid in the Rodent Hindbrain*. Endocrinology, 139(1), 29-34.
Mercer JG, Beck B, Burlet A, Moar KM, Hoggard N, Atkinson T & Barrett P (1998) Leptin (ob) mRNA and Hypothalamic NPY in Food-deprived/refed Syrian Hamsters. Physiology & Behavior, 64(2), 191-195.
Goldstone AP, Mercer JG, Gunn I, Moar KM, Edwards CMB, Rossi M, Howard JK, Rasheed S, Turton MD, Small C , Heath MM et al (1997) Leptin interacts with glucagon-like peptide-1 neurons to reduce food intake and body weight in rodents. FEBS Letters, 415(2), 134-138.
Mercer JG, Moar KM, Rayner DV, Trayhurn P & Hoggard N (1997) Regulation of leptin receptor and NPY gene expression in hypothalamus of leptin-treated obese (ob/ob ) and cold-exposed lean mice. FEBS Letters, 402(2-3), 185-188.
Rayner DV, Dalgliesh GD, Duncan JS, Hardie LJ, Hoggard N & Trayhurn P (1997) Postnatal development of the ob gene system: elevated leptin levels in suckling fa/fa rats. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 273(1), R446-R450.
Hoggard N, Mercer JG, Rayner DV, Moar K, Trayhurn P & Williams LM (1997) Localization of Leptin Receptor mRNA Splice Variants in Murine Peripheral Tissues by RT-PCR andin SituHybridization. Biochemical and Biophysical Research Communications, 232(2), 383-387.
Mitchell SE, Rees WD, Hardie LJ, Hoggard N, Tadayyon M, Arch JRS & Trayhurn P (1997) obGene Expression and Secretion of Leptin Following Differentiation of Rat Preadipocytes to Adipocytes in Primary Culture. Biochemical and Biophysical Research Communications, 230(2), 360-364.
Mercer JG, Hoggard N, Williams LM, Lawrence CB, Hannah LT, Morgan PJ & Trayhurn P (1996) Coexpression of Leptin Receptor and Preproneuropeptide Y mRNA in Arcuate Nucleus of Mouse Hypothalamus. Journal of Neuroendocrinology, 8(10), 733-735.
Mercer JG, Hoggard N, Williams LM, Lawrence CB, Hannah LT & Trayhurn P (1996) Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization. FEBS Letters, 387(2-3), 113-116.
Hadjivassiliou M, Blackburn D, O’Malley R & Hoggard N () IgG4 Disease-Related Ataxia. The Cerebellum.
Hadjivassiliou M, Currò R, Beauchamp N, Dominik N, Grunewald RA, Shanmugarajah P, Zis P, Hoggard N & Cortese A () Can CANVAS due toRFC1biallelic expansions present with pure ataxia?. Journal of Neurology, Neurosurgery & Psychiatry.
Kon FC, Hoggard N, Gillett G & Hadjivassiliou M () Encephalopathy with Guillain-Barré syndrome: seek a different cause. Practical Neurology.
Grohmann T, Walker AW, Russell WR, Hoggard N, Zhang X, Horgan G & de Roos B () A grape seed and bilberry extract reduces blood pressure in individuals at risk of developing type 2 diabetes: the PRECISE study, a double-blind placebo-controlled cross-over intervention study. Frontiers in Nutrition, 10.
Toh C, Keslake A, Payne T, Onwuegbuzie A, Harding J, Baster K, Hoggard N, Shaw PJ, Wilkinson ID & Jenkins TM () Analysis of brain and spinal MRI measures in a common domain to investigate directional neurodegeneration in motor neuron disease. Journal of Neurology.
Shuaib H, Barker GJ, Sasieni P, De Vita E, Chelliah A, Andrei R, Ashkan K, Beaumont E, Brazil L, Rowland-Hill C , Lau A et al () Overcoming challenges of translating deep learning models for Glioblastoma: the ZGBM consortium. The British Journal of Radiology.
Grohmann T, Litts C, Horgan G, Zhang X, Hoggard N, Russell W & de Roos B () Efficacy of Bilberry and Grape Seed Extract Supplement Interventions to Improve Glucose and Cholesterol Metabolism and Blood Pressure in Different Populations—A Systematic Review of the Literature. Nutrients, 13(5), 1692-1692.
Flores Martin A, Shanmugarajah P, Hoggard N & Hadjivassiliou M () Treatment Response of Deferiprone in Infratentorial Superficial Siderosis: a Systematic Review. The Cerebellum.
Hadjivassiliou M, Sarrigiannis PG, Shanmugarajah PD, Sanders DS, Grünewald RA, Zis P & Hoggard N () Clinical Characteristics and Management of 50 Patients with Anti-GAD Ataxia: Gluten-Free Diet Has a Major Impact. The Cerebellum.
Pattrick M, Sarrigiannis PG, Kruger S, Davies B, Hoggard N, Irani SR, Unwin Z, Zis P, Blackburn DJ & Hadjivassiliou M () Brain hyper-excitability in DPPX ataxia. Journal of Neurology.
Croall ID, Hoggard N, Aziz I, Hadjivassiliou M & Sanders DS () Brain fog and non-coeliac gluten sensitivity: Proof of concept brain MRI pilot study. PLOS ONE, 15(8), e0238283-e0238283.
Hadjivassiliou M, Grünewald R, Sanders D, Zis P, Croall I, Shanmugarajah P, Sarrigiannis P, Trott N, Wild G & Hoggard N () The Significance of Low Titre Antigliadin Antibodies in the Diagnosis of Gluten Ataxia. Nutrients, 10(10), 1444-1444.
Khandanpour N, Connolly D, Raghavan A, Griffiths P & Hoggard N () Kraniospinale Anomalien und neurologische Komplikationen bei Osteogenesis imperfecta: Bildgebung im Überblick. Neuroradiologie Scan, 03(04), 285-298.
Shore A, Emes RD, Wessely F, Kemp P, Cillo C, D’Armiento M, Hoggard N & Lomax MA () A Comparative Approach to Understanding Tissue-Specific Expression of Uncoupling Protein 1 Expression in Adipose Tissue. Frontiers in Genetics, 3.
Friedman SN, Bambrough PJ, Kotsarini C, Khandanpour N & Hoggard N () Semi-automated and automated glioma grading using dynamic susceptibility-weighted contrast-enhanced perfusion MRI relative cerebral blood volume measurements.. Br J Radiol.
Delibegovic M, Hoggard , Mody & Agouni () Serum levels of RBP4 and adipose tissue levels of PTP1B are increased in obese men resident in northeast Scotland without associated changes in ER stress response genes. International Journal of General Medicine, 403-403.
Valle A, Hoggard N, Adams AC, Roca P & Speakman JR () Chronic central administration of apelin-13 over ten days increases food intake, body weight, locomotor activity and body temperature in C57BL/6 mice. Journal of Neuroendocrinology, ja(ja), 070927052250001-070927052250001.
Mercer , Moar , Hoggard , Strosberg , Froguel & Bailleul () B219/OB-R 5′-UTR and Leptin Receptor Gene-Related Protein Gene Expression in Mouse Brain and Placenta: Tissue-Specific Leptin Receptor Promoter Activity. Journal of Neuroendocrinology, 12(7), 649-655.
Hadjivassiliou M, Graus F, Honnorat J, Jarius S, Titulaer M, Manto M, Hoggard N, Sarrigiannis P & Mitoma H () Diagnostic criteria for primary autoimmune cerebellar ataxia—guidelines from an international task force on immune-mediated cerebellar ataxias. The Cerebellum. View this article in WRRO
Hadjivassiliou M, Grunewald R, Shanmugarajah P, Sarrigiannis P, Zis P, Skarlatou V & Hoggard N () Treatment of primary autoimmune cerebellar ataxia with mycophenolate. The Cerebellum. View this article in WRRO
Jenkins TM, Alix JJP, Fingret J, Esmail T, Hoggard N, Baster K, McDermott CJ, Wilkinson ID & Shaw PJ () Longitudinal multi-modal muscle-based biomarker assessment in motor neuron disease. Journal of Neurology. View this article in WRRO
Sassani M, Alix J, McDermott C, Baster K, Hoggard N, Wild J, Mortiboys H, Shaw P, Wilkinson I & Jenkins T () Magnetic resonance spectroscopy reveals mitochondrial dysfunction in amyotrophic lateral sclerosis. Brain.
Anton A, Mead RJ, Shaw PJ, Edden RAE, Bigley J, Jenkins TM, Wild JM, Hoggard N & Wilkinson ID () Assessment of the Precision in Measuring Glutathione at 3 T With a MEGA‐PRESS Sequence in Primary Motor Cortex and Occipital Cortex. Journal of Magnetic Resonance Imaging.

Conference proceedings papers

Kon FC, Akil M, Kilding R, Kuet K-P, Shanmugarajah P, Hoggard N & Hadjivassiliou M (2021) Cerebellar Ataxia in Primary Sjogren's Syndrome, Is Gluten Sensitivity the Answer?. ARTHRITIS & RHEUMATOLOGY, Vol. 73 (pp 624-625)
Paling D, Hardy T, Khan A, Redgrave J, Hoggard N, Coley S, Dyde R, Malley RO & Yasiry Z (2020) Balo's concentric sclerosis successfully treated with alemtuzumab. MULTIPLE SCLEROSIS JOURNAL, Vol. 26(3_SUPPL) (pp 264-264)
Toh CL, Keslake A, Harding J, Baster K, Hoggard N, Bigley J, McDermott CJ, Shaw PJ, Wilkinson ID & Jenkins TM (2019) 222 Investigating directionality of neurodegeneration in vivo in ALS using multimodal MRI. Journal of Neurology Neurosurgery & Psychiatry, Vol. 90(12) (pp e55)
Toh C, Keslake A, Harding J, Baster K, Hoggard N, Bigley J, McDermott CJ, Shaw PJ, Wilkinson ID & Jenkins TM (2019) Investigating Directionality of Neurodegeneration in vivo in ALS using Multimodal MRI. NEUROLOGY, Vol. 92(15)
J H, L K-I, S B, L B, S P, A S, N H, M R & D P (2018) THUR 198 Safe monitoring of natalizumab therapy in multiple sclerosis. Journal of Neurology, Neurosurgery & Psychiatry, Vol. 89(10) (pp A29.1-A29)
Jenkins TM, Alix J, Hoggard N, Rao G, O'brien E, Baster K, Bigley J, Wilkinson I, McDermott C & Shaw P (2018) Imaging denervation in amyotrophic lateral sclerosis for future clinical trials: 12-month follow-up from a longitudinal cohort study. EUROPEAN JOURNAL OF NEUROLOGY, Vol. 25 (pp 302-302)
Jenkins T, Alix J, Rao G, Hoggard N, O'Brien E, Baster K, Bradburn M, Bigley J, McDermott C, Wilkinson I & Shaw P (2017) Imaging denervation in motor neuron disease for future clinical trials: a longitudinal cohort study. Journal of the Neurological Sciences, Vol. 381 (pp 102-102) View this article in WRRO
Hewamadduma CA, Omalley R, Robinson M, Beauchamp N, Rogers T, Martindale J, Mcdermott C, Shaw P, Hoggard N & Hadjivassiliou M (2017) Mutations in SPG7 as an important cause of spastic-ataxia in a large british cohort: Hybrid phenotype helps direct screening. Journal of the Neurological Sciences, Vol. 381 (pp 304-305) View this article in WRRO
Penny HA, Aziz I, Ferrar M, Atkinson J, Hoggard N, Hadjivassiliou M, West JN & Sanders DS (2016) PWE-055 Coeliac Disease is More Common in Subjects with Postural Orthostatic Tachycardia Syndrome Compared to Healthy Controls. Gut, Vol. 65(Suppl 1) (pp A165.2-A166)
Wong L, Sharp P, Howarth C, Hoggard N, Berwick J & Francis S (2016) 179 Neurovascular Function in Atherosclerosis. Heart, Vol. 102(Suppl 6) (pp A123.2-A124), 6 June 2016 - 8 June 2016.
Raftopoulos R, Hickman S, Toosy A, Sharrack B, Malliki S, Paling D, Altman D, Yiannakas M, Malladi P, Sheridan R , Sarrigiannis P et al (2016) Prognostic Factors Associated with Axonal Loss after Optic Neuritis. NEUROLOGY, Vol. 86
Raftopoulos R, Hickman S, Toosy A, Sharrack B, Mallik S, Paling D, Altmann D, Yiannakas M, Malladi P, Sheridan R , Sarrigiannis P et al (2016) Prognostic Factors Associated with Axonal Loss after Optic Neuritis. NEUROLOGY, Vol. 86
Penny HA, Ferrar M, Atkinson J, Hoggard N, Hadjivassiliou M, West JN & Sanders DS (2015) PTU-184 Is there a relationship between gluten ingestion and postural tachycardia syndrome?. Gut, Vol. 64(Suppl 1) (pp A144.1-A144)
Bahl A, Larsen JJ, Craven I, Metherall P, McKevitt FM, Romanowski CAJ, Hoggard N & Jellinek DA (2012) TRANSFORMATION OF LOW-GRADE GLIOMA ASSESSED BY VOLUMETRIC 3T MRI. NEURO-ONCOLOGY, Vol. 14 (pp 4-4)
Hadjivassiliou M, Currie S, Sanders D & Hoggard N (2012) Alcoholic Cerebellar Degeneration: Not All Due to Alcohol. ANNALS OF NEUROLOGY, Vol. 72 (pp S96-S96)
Romanowski CA, Hoggard N, Jellinek DA, Clenton S, McKevitt F, Wharton S, Craven I, Buller A, Waddle C, Bigley J , Wilkinson ID et al (2011) SEMI-AUTOMATED VOLUMETRIC ANALYSIS OF LOW-GRADE GLIOMAS. NEURO-ONCOLOGY, Vol. 13 (pp 140-140)
Ireland RH, Wild JM, Woodhouse N, Hoggard N, Brown G, Swinscoe JA, Din O & Hatton MQ (2008) Can hyperpolarized He-3 MRI detect radiation induced lung damage?. LUNG CANCER, Vol. 60 (pp S28-S28)
Jellinek D, Hoggard N, Wilkinson I, Levy D, Giesel F, Romanowski C, Miller B & Griffiths P (2007) Dexamethasone and enhancing gliomas: Alterations in perfusion and blood-tumor barrier kinetics shown by magnetic resonace imaging. NEURO-ONCOLOGY, Vol. 9(4) (pp 578-578)
Ireland R, Woodhouse N, Hoggard N, Beek E, Swinscoe J, Brown G, Hatton M & Wild J (2007) Improved image registration of hyperpolarized helium-3 MRI and CT for NSCLC planning. RADIOTHERAPY AND ONCOLOGY, Vol. 84 (pp S173-S173)
Ireland RH, Wood SM, Hanney MB, Tindale WB, Dyker KE, Robinson MH, Woodhouse N, Hoggard N, Conway J, Swinscoe JA & Barber DC (2007) Non-rigid Registration Enables Radiotherapy Treatment Planning with Staging PET. Clinical Oncology, Vol. 19(3) (pp S5-S5)
Hoggard N, Haggarty P, Thomas L & Lea RG (2001) Leptin expression in placental and fetal tissues: Does leptin have a functional role?. Biochemical Society Transactions, Vol. 29(2) (pp 57-63)
RAYNER DV, ATKINSON T, DALGLEISH GD, DUNCAN JS, HOGGARD N & TRAYHURN P (1998) Hyperleptinaemia precedes hyperinsulinaemia in Zucker (fa/fa) rats. Biochemical Society Transactions, Vol. 26(2) (pp S98-S98)

Preprints

Tse GH, Hadjivassiliou M, Devgire V, Hobson E, Connolly DJA & Hoggard N () IgG4-related Disease Presenting With Ataxia , Research Square Platform LLC.
Mahatma M, Jayasuriya R, Hughes D, Hoggard N, Buckley S, Gordon A, Hamer A, Tomouk W, Kerry R, Eastell R & Wilkinson JM () Effect of Denosumab on Osteolytic Lesion Activity after Total Hip Arthroplasty: A Single-Centre, Randomised, Double-Blind, Placebo-Controlled, Proof-of-Concept Study.

Teaching interests: I am the lead for the Sheffield academic clinical radiology training scheme and Deputy Lead for the Sheffield academic training programme. The Sheffield radiology training scheme continues to show strong success developing academic radiologists all the way from thesis to tenured full time academic posts. I teach on the Neurology MSc course, the Sheffield Fundamentals of Neuroradiology course and the National ENT radiology Masterclass.

Professional activities and memberships

Editor-in-Chief British Journal of Radiology 2013-2016.
Expert Advisory Panel member, Commission for Human Medicines/MHRA 2009-present.
Expert Advisory Panel member, European Medicines Agency 2016.
Cancer Peer reviewer 2012-2013.
Member of the Royal College of Radiologists FRCR part I examination committee 2011-2014.
NIHR doctoral research fellowship selection panel member 2011 and 2013-present.
NIHR IAT panel for competitive bids for ACF and ACL posts 2015-present.
Sheffield Teaching Hospitals NHS Foundation Trust, Research Lead for the Directorate of Radiology 2008-present.
Member of the Sheffield Regional Ethics committee 2006-2012.