Professor Walter Marcotti

Walter MarcottiProfessor of Sensory Neuroscience
Wellcome Trust Senior Investigator
Department of Biomedical Science
Centre for Sensory Neuroscience
Alfred Denny Building (B1 221)
University of Sheffield
Western Bank
Sheffield, S10 2TN, UK

Room: B1 221 Alfred Denny
Telephone: +44 (0) 114 222 1098

Research Summary

One of the challenges in modern medicine is to develop gene and stem cell therapeutic strategies to treat deafness by targeting specific genes that play a crucial role in the generation of the disease. In all cases, it is important to understand how the auditory system normally develops and operates and how defects at molecular level lead to deafness. Moreover, understanding how the ear processes sound is essential to further technical and software development of hearing aids, including cochlear implants.

In my laboratory, we aim to identify the normal development of the mammalian auditory system and, most importantly, to determine the functional/physiological consequences of genes that when mutated cause deafness in humans.This is achieved by studying the physiological properties of the individual sensory hair cells of the mammalian cochlea using electrophysiological, calcium imaging and molecular biology techniques.

Read more on research in the Marcotti laboratory

Career history

  • 2012 - present: Professor of Sensory Neuroscience
  • 2006 - present: Royal Society University Research Fellow, University of Sheffield, UK.
  • 2004 - 2005: Royal Society University Research Fellow, University of Sussex, UK.
  • 2001 - 2004: Postdoctoral Fellow, University of Sussex, UK.
  • 1997 - 2000: Postdoctoral Fellow, University of Bristol, UK.
  • 1994 - 1997: PhD, University of Pavia, Italy.
  • 1989 - 1992: University Degree in Biological Science, University of Pavia, Pavia, Italy.

Grants and funding

Recent publications

Full publications.