The University of Sheffield
Department of Chemistry

Tony RyanProf. Anthony J. Ryan, OBE

Pro-vice Chancellor of the Faculty of Science &

Professor of Physical Chemistry

Room: D106, Addison Building

Tel: +44-(0)114-22-29760

Tel. Assistant: +44-0(114)-22-29761 (Angela Simonite)

Fax: +44-(0)114-22-29436

email:

 


 

Biographical Sketch

Professor Tony Ryan was a student at the University of Manchester Institute of Science and Technology (UMIST) where awarded a BSc in Polymer Science & Technology (Chemistry) in 1983 and a PhD in 1988. From 1985 to 1988 he was a Lecturer in Polymer Science & Technology at UMIST. He held a NATO Research Fellowship at the University of Minnesota in 1988 and 1989. In 1990 he returned to UMIST to be a Lecturer in Polymer Science & Technology in the Materials Science Department and was promoted to Senior Lecturer in 1994 and Reader in 1995. From 1993 to 1997 he was seconded half-time to the Synchrotron Radiation Source at Daresbury. In 1997 he moved to Sheffield to be The Professor of Physical Chemistry. From 1999-2004 he was the Head of the Department of Chemistry, from 2000-2008 Director of the Polymer Centre 2000-2008, and in the period 2002-2008 The ICI Professor of Physical Chemistry. In 2008 he became the Pro Vice Chancellor for the Faculty of Science at the University of Sheffield.

Awards

The Plastics and Rubber Institute Silver Medal 1990; The Akzo Chemical Award 1990; Royal Society of Chemistry Thermal Methods Group Award 1992; The Morand Lambla Award of the Polymer Processing Society 1999; The Beilby Medal and Prize of the Royal Society of Chemistry 1999; Royal Society of Chemistry Environmentally Friendly Polymers Award 2003; Officer of the British Empire, OBE, for “services to science” 2006; Ellison-Cliffe Medal & Lecture, Royal Medical Society 2007; Maitland Medal & Lecture, Institute of Structural Engineers 2008; Gold Medal of the Society of Dyers and Colourists 2008; MacroGroup UK Medal, RSC/SCI/IoP 2009; RSC Materials Division Schools Lecturer 2011.

Research Keywords

Polymer Nanotechnology (synthesis, processing, self-assembly, structure-property relations),
Public engagement in science and technology.

Teaching Keywords

Physical Chemistry

Selected Publications:

  • From a Water-Immiscible Monomer to Block Copolymer Nano-Objects via a One-Pot RAFT Aqueous Dispersion Polymerization Formulation, L. P. D. Ratcliffe, A. J. Ryan and S. P. Armes, Macromolecules 2013, 46, 769-777.
  • Combined microfabrication and electrospinning to produce 3-D architectures for corneal repair, Ilida Ortega, Anthony J. Ryan, Pallavi Deshpande, Sheila MacNeil and Frederik Claeyssens, Acta Biomaterialia 2013, 9, 5511-5520.
  • Effect of Matrix Polymer on Flow-Induced Nucleation in Polymer Blends, Masayuki Okura, Oleksandr O. Mykhaylyk and Anthony J. Ryan, Phys. Rev. Lett. 2013, 110.
  • Moisture Permeation in Liquid Crystalline Epoxy Thermosets, Lei Nie, Andrew Burgess and Anthony Ryan, Macromol. Chem. Phys. 2013, 214, 225-235.
  • Sterilizable Gels from Thermoresponsive Block Copolymer Worms, Adam Blanazs, Robert Verber, Oleksandr O. Mykhaylyk, Anthony J. Ryan, Jason Z. Heath, C. W. Ian Douglas and Steven P. Armes, J. Am. Chem. Soc. 2012, 134, 9741-9748.
  • Predictive Phase Diagrams for RAFT Aqueous Dispersion Polymerization: Effect of Block Copolymer Composition, Molecular Weight, and Copolymer Concentration, A. Blanazs, A. J. Ryan and S. P. Armes, Macromolecules 2012, 45, 5099-5107.
  • Using Multimodal Blends to Elucidate the Mechanism of Flow-Induced Crystallization in Polymers, Masayuki Okura, Pierre Chambon, Oleksandr O. Mykhaylyk, J. Patrick A. Fairclough and Anthony J. Ryan, Journal of Polymer Science Part B-Polymer Physics 2011, 49, 621-628.
  • A Phase Diagram of the P3HT:PCBM Organic Photovoltaic System: Implications for Device Processing and Performance, Paul E. Hopkinson, Paul A. Staniec, Andrew J. Pearson, Alan D. F. Dunbar, Tao Wang, Anthony J. Ryan, Richard A. L. Jones, David G. Lidzey and Athene M. Donald, Macromolecules 2011, 44, 2908-2917.
  • Self-assembly of double hydrophilic block copolymers in concentrated aqueous solution, Adam Blanazs, Nicholas J. Warren, Andrew L. Lewis, Steven P. Armes and Anthony J. Ryan, Soft Matter 2011, 7, 6399-6403.
  • Controlling Polymersome Surface Topology at the Nanoscale by Membrane Confined Polymer/Polymer Phase Separation, Caterina LoPresti, Marzia Massignani, Christine Fernyhough, Adam Blanazs, Anthony J. Ryan, Jeppe Madsen, Nicholas J. Warren, Steven P. Armes, Andrew L. Lewis, Somyot Chirasatitsin, Adam J. Engler and Giuseppe Battaglia, Acs Nano 2011, 5, 1775-1784. 

Research Interests

The common theme in my research is phase transitions in polymers. Most recently we have used the knowledge of the thermodynamics and kinetics of phase behaviour in polymer blends and block copolymers to develop new processing methods based on self-assembly. This has led to the development of the new field of Soft Nanotechnology where synthetic and natural macromolecules are harnessed in a way that makes use of their intrinsic flexibility and susceptibility to Brownian motion to generate work from changes on molecular conformation. Developments in polymers responsive to their environment have lead to research into molecular machines, specifically the fabrication of molecular valves and motors.

We do polymer synthesis in order to have well defined systems to study. The dynamics of phase behaviour are studied by calorimetry, spectroscopy, rheology, microscopy and light, X-ray or neutron scattering. A full suite of microstructural analysis (atomic force, optical and electron microscopy, X-ray diffraction and mechanical testing) is used to confirm the dynamic experiments and where appropriate computer modelling is also used.

My main contribution to the field has been the development and application of the techniques of time-resolved structural tools to polymers. This work was the subject of prizes in 1990 by the Plastics and Rubber Institute, in 1992, 1999 and 2003 from the Royal Society of Chemistry and in 1999 from the Polymer Processing Society.

I have been active in promulgating the public understanding of science since my graduate student days. This culminated in my appointment as the Royal Institution Christmas Lecturer for 2002 where my theme was the science and technology of everyday things. The lectures were seen on Channel 4 by 4.5 million viewers and have also been broadcast in Europe, Japan and Korea. I was also the 1st EPSRC Senior Media Fellow to allow me to combine world-class research and popular understanding of the impact of science and technology on society. I was awarded an OBE in 2005 for "services to science".

Teaching Section

Physical Chemistry

Undergraduate Courses Taught

  • Phase equilibria (Year 2)
    The aim of this course is to apply the laws of thermodynamics to phase equilibria.
  • Equilibrium and Electrochemistry (Year 2)
    The aim of this segment is to develop an understanding of chemical equilibrium, the formation of electrochemical potentials and their exploitation for practical applications.

Books

  • Ryan AJ & Britain RSOCG (2001) Emerging themes in polymer science. Springer Us/Rsc.
  • Wilkinson AN & Ryan AJ (1999) Polymer processing and structure development. Kluwer Academic Pub.

Journal articles

Chapters

  • Ryan AJ (2005) Self-Organising Polymers In GB RSOC (Ed.), Self-Organising Polymers Springer Us/Rsc.

Conferences

  • Ratcliffe LPD, Ryan AJ & Armes SP (2013) From a water-immiscible monomer to block copolymer nano-objects via a one-pot RAFT aqueous dispersion polymerization formulation. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 245
  • Sefat F, McKean R, Deshpande P, Ramachandran C, Hill CJ, Sangwan VS, Ryan AJ & MacNeil S (2013) Production, sterilisation and storage of biodegradable electrospun PLGA membranes for delivery of limbal stem cells to the cornea. 3RD INTERNATIONAL CONFERENCE ON TISSUE ENGINEERING (ICTE2013), Vol. 59 (pp 101-116)
  • Ryan AJ, Odedra R, James N, Ratcliffe K, Marshall G, Howard Z, Jackson L, Baker D, Smith N & Brave SR (2008) Bench to bedside - Bedside to bench: Preclinical determination of the potential pharmacological activities of vandetanib in the clinic. EJC SUPPLEMENTS, Vol. 6(12) (pp 184-184)
  • Smith NR, Baker DJ, James NH, Ratcliffe KE, Ashton SE, Gray N, Ryan AJ, Jurgensmeier JM & Womack C (2008) VEGF receptor expression in human tumours: VEGFR-2 and-3 are confined predominantly to tumour vasculature. EJC SUPPLEMENTS, Vol. 6(12) (pp 18-18)
  • Topham PD, Sandon N, Read ES, Madsen J, Ryan AJ & Armes SP (2008) POLY 390-Facile synthesis of well-defined macromonomers using ATRP and click chemistry. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 236
  • Chambon P, Fernyhough CM & Ryan AJ (2008) POLY 93-Synthesis and characterization of model materials as part of the "microscale polymer processing 2" project. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 236
  • Blanazs A, Massignani M, Battaglia G, Armes SP & Ryan AJ (2008) Synthesis of pH-responsive amphiphilic ABC block copolymers: The generation of asymmetric vesicle membranes and their cell uptake kinetics. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 236
  • Mykhaylyk OO, Chambon P, Graham RS, Fairclough JPA, Olmsted PD & Ryan AJ (2008) The specific work of flow as a universal parameter to control the formation of shish-kebab morphology in polymers. XVTH INTERNATIONAL CONGRESS ON RHEOLOGY - THE SOCIETY OF RHEOLOGY 80TH ANNUAL MEETING, PTS 1 AND 2, Vol. 1027 (pp 496-498)
  • Blackwood K, Freeman CO, McKean R, Farthing P, Haycock JW, Ryan AJ, Brook I & MacNeil S (2007) Development of biocompatible, biodegradable electrospun scaffolds for tissue engineering of human skin. TISSUE ENGINEERING, Vol. 13(7) (pp 1670-1671)
  • Goodchild RL, Hatton PV, Ryan AJ, Norton D, Reaney IM, Migliaresi C & Maniglio D (2007) Evaluation of chondrocyte response to electrospun polymer-ceramic composite scaffolds. TISSUE ENGINEERING, Vol. 13(7) (pp 1691-1691)
  • Canton I, Sarwar U, Kemp EH, Watson PF, Ryan AJ, MacNeil S & Haycock JW (2007) Real time detection of stress in 3D tissue engineered constructs using NF-kB activation in transiently transfected human dermal fibroblasts. TISSUE ENGINEERING, Vol. 13(7) (pp 1750-1750)
  • Mykhaylyk OO, Smith KW, Martin CM & Ryan AJ (2007) Structural models of metastable phases occurring during the crystallization process of saturated/unsaturated triacylglycerols. JOURNAL OF APPLIED CRYSTALLOGRAPHY, Vol. 40 (pp S297-S302)
  • Mykhaylyk OO, Ryan AJ, Tzokova N & Williams N (2007) The application of distance distribution functions to structural analysis of core-shell particles. JOURNAL OF APPLIED CRYSTALLOGRAPHY, Vol. 40 (pp S506-S511)
  • Topham PD, Howse JR, Crook CJ, Gleeson AJ, Bras W, Armes SP, Jones RAL & Ryan AJ (2007) Autonomous volume transitions of a polybase triblock copolymer gel in a chemically driven pH-oscillator. MACROMOLECULAR SYMPOSIA, Vol. 256 (pp 95-104)
  • Fernyhough CM, Ryan AJ, Waigh TA & Papagiannopoulos A (2005) Synthesis and characterization of biomimetic polystyrene sulfonate combs. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 230 (pp U4341-U4341)
  • Loo YL, Lai C, Adamson DH, Ryan AJ & Register RA (2005) Thermoreversible transitions to and from the hexagonally-perfoated lamellar structure in diblock copolymers. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 230 (pp U3591-U3591)
  • Heeley EL, Gough T, Bras W, Gleeson AJ, Coates PD & Ryan AJ (2005) Polymer processing: Using synchrotron radiation to follow structure development in commercial and novel polymer materials. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS, Vol. 238(1-4) (pp 21-27)
  • Battaglia G & Ryan AJ (2005) Morphology and formation of interdigitated membrane polymeric vesicles from polyethylene oxide polybutylene oxide diblock, aba, and bab triblocks copolymers.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 229 (pp U916-U916)
  • Ryan AJ, Heeley EL, Fernyhough CM, Morgovan A, Gough T & Bras W (2004) How does flow affect polymer crystallisation?. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 228 (pp U440-U440)
  • Ryan AJ (2004) Polymers, particles and pits: The evolution of recording media.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 228 (pp U332-U332)
  • Crook CJ, Cadby A, Smith A, Jones RAL & Ryan AJ (2004) Measurement of force produced by a pH-responsive hydrogel in a pH oscillator. NONLINEAR DYNAMICS IN POLYMERIC SYSTEMS, Vol. 869 (pp 71-79)
  • Norman AI, Fairclough JPA, Mai S & Ryan AJ (2004) Poly(oxyalkylene) block copolymers in aqueous solution - Phase behavior and transition kinetics. JOURNAL OF MACROMOLECULAR SCIENCE-PHYSICS, Vol. B43(1) (pp 71-93)
  • Sutton D, Stanford JL & Ryan AJ (2004) Reaction-induced phase separation in polyoxyethylene/polystyrene blends. I. Ternary phase diagram. JOURNAL OF MACROMOLECULAR SCIENCE-PHYSICS, Vol. B43(1) (pp 219-232)
  • Xu JT, Fairclough JPA, Mai SM & Ryan AJ (2003) The effect of architecture on the morphology and crystallization of oxyethylene/oxybutylene block copolymers from micelles in n-hexane. JOURNAL OF MATERIALS CHEMISTRY, Vol. 13(11) (pp 2740-2748)
  • Olmsted PD, Maidens AV, Ryan AJ & Heeley E (2003) Metastable phases and the nature of the melt state in polymer melts.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 226 (pp U272-U273)
  • Bras W, Dolbnya IP, Detollenaere D, van Tol R, Malfois M, Greaves GN, Ryan AJ & Heeley E (2003) Recent experiments on a combined small-angle/wide-angle X-ray scattering beam line at the ESRF. JOURNAL OF APPLIED CRYSTALLOGRAPHY, Vol. 36 (pp 791-794)
  • Ryan AJ (2003) Body armour.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 225 (pp U587-U588)
  • Pokric B, Allinson NM, Ryan AJ, Fairclough P, Dobson BR, Derbyshire GE, Helsby W, Long G & Moon K (2002) A double area detector system for simultaneous small and wide-angle X-ray scattering. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, Vol. 477(1-3) (pp 329-334)
  • Xu JT, Wu F, Fan ZQ & Ryan AJ (2002) Phase separation in the melt of polypropylene-1-decene copolymers. JOURNAL OF MACROMOLECULAR SCIENCE-PHYSICS, Vol. B41(4-6) (pp 1331-1348)
  • Stanford JL, Ryan AJ & Yang Y (2001) The formation and properties of acrylic-polyurea interpenetrating networks formed by reaction injection moulding (RIM). MACROMOLECULAR SYMPOSIA, Vol. 171 (pp 139-149)
  • Corvazier L, Messe L, Salou CLO, Young RN, Fairclough JPA & Ryan AJ (2001) Lamellar phases and microemulsions in model ternary blends containing amphiphilic block copolymers. JOURNAL OF MATERIALS CHEMISTRY, Vol. 11(11) (pp 2864-2874)
  • Sutton D, Stanford JL & Ryan AJ (2001) Structure-property relations in reaction-induced, phase-separated poly(2-phenoxyethyl acrylate)/polystyrene blends. JOURNAL OF MACROMOLECULAR SCIENCE-PHYSICS, Vol. B40(3-4) (pp 485-506)
  • Ryan AJ, Terrill NJ & Fairclough JPA (2000) A scattering study of nucleation phenomena in homopolymer melts. SCATTERING FROM POLYMERS, Vol. 739 (pp 201-217)
  • Ryan AJ (2000) Modern structural characterization techniques using synchrotron radiation to study structure development. STRUCTURE DEVELOPMENT DURING POLYMER PROCESSING, Vol. 370 (pp 69-91)
  • Bras W & Ryan AJ (1997) Time-resolved small-angle X-ray scattering combined with wide-angle X-ray scattering. JOURNAL OF APPLIED CRYSTALLOGRAPHY, Vol. 30(2) (pp 816-821)
  • Elwell MJ, Ryan AJ, Grunbauer HJM & vanLieshout HC (1997) Polymer structure development during reactive processing: In situ studies of a cellular, multiphase block copolymer. POLYMERIC FOAMS, Vol. 669 (pp 143-164)
  • Bras W & Ryan AJ (1996) Small-angle X-ray scattering and wide-angle X-ray scattering experiments combined with thermal and spectroscopic analysis techniques. JOURNAL OF MOLECULAR STRUCTURE, Vol. 383(1-3) (pp 309-314)
  • ELWELL MJ, MORTIMER S, RYAN AJ & BRAS W (1995) A SYNCHROTRON SAXS STUDY OF THE STRUCTURE DEVELOPMENT KINETICS DURING THE REACTIVE PROCESSING OF FLEXIBLE POLYURETHANE FOAM. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS, Vol. 97(1-4) (pp 261-264)
  • BOGG D, DERBYSHIRE GE, BRAS W, COOKE J, ELWELL MJA, NAYLOR S & RYAN AJ (1995) COMBINED SMALL-ANGLE X-RAY-SCATTERING (SAXS) AND FOURIER-TRANSFORM INFRARED (FT-IR) SPECTROSCOPY IN A TIME-RESOLVED MODE USING SYNCHROTRON-RADIATION. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS, Vol. 97(1-4) (pp 536-538)
  • NAYLOR S, BRAS W, DERBYSHIRE G, MANT GR, BOGG D & RYAN AJ (1995) SIMULTANEOUS TIME-RESOLVED SYNCHROTRON X-RAY-SCATTERING STUDIES ON BLOCK COPOLY(ETHER-URETHANE) PHASE-BEHAVIOR. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS, Vol. 97(1-4) (pp 253-256)
  • MARCOSFERNANDEZ A, RYAN AJ & GONZALEZ L (1995) STRUCTURE-PROPERTY RELATIONS IN MULTIBLOCK COPOLY(ETHER-UREA)S STUDIED BY SAXS, DSC AND THERMOMECHANICAL TECHNIQUES. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS, Vol. 97(1-4) (pp 279-281)
  • COOKE J, RYAN AJ & BRAS W (1995) TIME-RESOLVED X-RAY STUDIES OF POLYMORPHISM IN ISOTACTIC POLYBUT-1-ENE. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS, Vol. 97(1-4) (pp 269-272)
  • RYAN AJ, ELWELL MJ & BRAS W (1995) USING SYNCHROTRON-RADIATION TO STUDY POLYMER PROCESSING. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS, Vol. 97(1-4) (pp 216-223)
  • BRAS W, MANT GR, DERBYSHIRE GE, BOUCH D, SHELDON J, DINGS J & RYAN AJ (1995) MULTIPLE SIMULTANEOUS TIME-RESOLVED EXPERIMENTAL-TECHNIQUES. REVIEW OF SCIENTIFIC INSTRUMENTS, Vol. 66(2) (pp 1314-1316)
  • RYAN AJ, BRAS W, MANT GR & DERBYSHIRE GE (1994) A DIRECT METHOD TO DETERMINE THE DEGREE OF CRYSTALLINITY AND LAMELLAR THICKNESS OF POLYMERS - APPLICATION TO POLYETHYLENE. POLYMER, Vol. 35(21) (pp 4537-4544)
  • RYAN AJ, NAYLOR S, KOMANSCHEK B, BRAS W, MANT GR & DERBYSHIRE GE (1994) POLYMER STRUCTURE DETERMINATION USING SIMULTANEOUS SMALL AND WIDE-ANGLE X-RAY-SCATTERING AND DIFFERENTIAL SCANNING CALORIMETRY. HYPHENATED TECHNIQUES IN POLYMER CHARACTERIZATION, Vol. 581 (pp 162-180)
  • BRAS W, DERBYSHIRE GE, RYAN AJ, MANT GR, MANNING P, CAMERON RE & MORMANN W (1993) SIMULTANEOUS TIME-RESOLVED X-RAY-SCATTERING EXPERIMENTS IN THE SMALL AND WIDE-ANGLE REGION. JOURNAL DE PHYSIQUE IV, Vol. 3(C8) (pp 447-450)
  • ELWELL MJ, RYAN AJ, GRUENBAURER HJM, VANLIESHOUT HC & THOEN JA (1993) A CORRELATED VIEW OF REACTION-KINETICS AND STRUCTURE DEVELOPMENT DURING THE REACTIVE PROCESSING OF WATER BLOWN, FLEXIBLE POLYURETHANE FOAM. CELLULAR POLYMERS (pp 101-109)
  • STANFORD JL, WILKINSON AN, LEE DK & RYAN AJ (1990) ENGINEERING PLASTICS FORMED BY REACTION INJECTION-MOLDING - HIGH-STIFFNESS AND HIGH-STRENGTH COPOLYUREAS. PLASTICS AND RUBBER PROCESSING AND APPLICATIONS, Vol. 13(2) (pp 111-119)
  • RYAN AJ, STANFORD JL & STILL RH (1990) STRUCTURE PROPERTY RELATIONS IN POLY(URETHANE-UREA)S AND POLYUREAS FORMED BY REACTION INJECTION-MOLDING - PHASE-SEPARATION STUDIES. PLASTICS AND RUBBER PROCESSING AND APPLICATIONS, Vol. 13(2) (pp 99-110)