Professor Sheila Macneil

BSc, PhD

Department of Materials Science and Engineering

Emeritus Professor of Tissue Engineering

Director, Interdisciplinary Programmes, Faculty of Engineering

Professor Sheila MacNeil
Profile

Sheila MacNeil joined the department in 2000 with an undergraduate degree in physiology from the University of Aberdeen and a doctorate on the endocrinology of manic depression from the Medical School of the University of Sheffield.

She is academic lead of the Biomaterials and Tissue Engineering Group within the Department. Members include Professor John Haycock, Readers Dr Ihtesham Rehman, Dr Steve Matcher and Senior Lecturers Dr CK Chong, Dr Frederik Claeyssens, Dr Gwen Reilly.

She has previously been Deputy Director of the Kroto Research Institute (from 2005 to 2009) and Director of the University Centre for Biomaterials and Tissue Engineering from 2002 to 2009, promoting interdisciplinary research between engineering, physical sciences and life sciences.

She was also a founding Director of the University of Sheffield spin-out company, CellTran Limited from 2000 to 2007. She was the Sheffield lead for an EPSRC Doctoral Training Centre in Tissue Engineering and Regenerative Medicine (a DTC held between three Universities, Leeds, Sheffield and York) from 2008 to 2011.

Research interests

Sheila's research focuses on developing tissue engineering to benefit patients, alongside fundamental work to develop new understanding and tools in the area of tissue engineering. Her primary research interests are in tissue engineering of soft tissues – skin, oral mucosa, urethra and cornea, with a strong focus on translating research for clinical benefit.

Her group have a long history of working with clinical NHS colleagues using tissue engineered skin to benefit burns patients (from 1992) and more recently patients with chronic ulcers (2004) and patients requiring reconstructive surgery of the urethra (from 2007).

She has developed the product Myskin™ which was clinically evaluated and developed commercially and has been available in the UK for patients with extensive skin loss due to burns injuries and to chronic non-healing ulcers from 2004 to the current time, currently available through the company Regenerys Ltd.

Additionally, she has developed 3D tissue engineered models used to study a wide range of normal and abnormal conditions spanning wound healing, skin contracture, pigmentation, melanoma invasion, angiogenesis, bacterial infection and skin sensitisation.

Centre for Biomaterials and Tissue Engineering

Postdoctoral research assistants

  • Dr Anthony Bullock
  • Dr Shweta Mittar
  • Dr Abigail Pinnock
  • Dr Marc Daigneault
  • Dr Sabiniano Roman Regueros

Clinical research fellows

  • Mr Nadir Osman
  • Ms Naside Mangir
  • Mr Chris Hillary

Sheila's current projects include developing tissue engineering approaches for reconstruction for burns contractures, for stimulating healing in chronic ulcers and she leads a group of scientists and clinicians developing a tissue engineering approach for repair of the weakened tissues of the female pelvic floor . She also has two Wellcome funded projects with India on corneal tissue engineering and early detection of infection in the cornea (with Professor Steve Rimmer in Chemistry and Professor Ian Douglas in Dentistry.)

Publications

Journal articles

Chapters

Conference proceedings papers

  • Murray K, MacNeil S & Spain S (2019) Development of a topical prodrug to treat burn scar contracture. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 257 RIS download Bibtex download
  • Dikici S, Mangir N, Kanczler J, Yar M, Oreffo R & MacNeil S (2018) Evaluation of the angiogenic and osteogenic activity of two potent alternatives to VEGF: 2-deoxy-D-ribose (2dDR) and 17 beta-Estradiol (E2) loaded tissue engineering scaffolds. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 256 RIS download Bibtex download
  • Roman S, Mangir N, Hympanova L, Deprest J, Chapple CR & MacNeil S (2018) USE OF ACCELERATED FATIGUE TESTING AS A SIMPLE IN VITRO TEST FOR ASSESSING MATERIALS FOR THE SURGICAL TREATMENT OF STRESS URINARY INCONTINENCE AND PELVIC ORGAN PROLAPSE. NEUROUROLOGY AND URODYNAMICS, Vol. 37 (pp S379-S380) RIS download Bibtex download
  • Pashneh-Tala S, Sherborne C, MacNeil S & Claeyssens F (2017) Tissue-Engineered Blood Vessels with User-Defined Geometries. TISSUE ENGINEERING PART A, Vol. 23 (pp S140-S140) RIS download Bibtex download
  • Hympanova L, Cunha M, Rynkevic R, Roman S, Gallego M, Vange J, Wach RA, Callewaert G, Urbankova I, Van der Aa F , Macneil S et al (2017) COMPARABLE VAGINALWALL BIOMECHANICAL PROPERTIES FOLLOWING ELECTROSPUN POLYCARBONATE- UREIDOPYRIMIDONE MESH IMPLANTATION AND SIMULATED NATIVE TISSUE REPAIR IN SHEEP. INTERNATIONAL UROGYNECOLOGY JOURNAL, Vol. 28 (pp S37-S38) RIS download Bibtex download
  • Doroshenko N, Rimmer S, Foster S, MacNeil S & Douglas I (2017) Corneal infections: targeted eradication through antibiotic functionalized polymers. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol. 58(8) RIS download Bibtex download
  • Boadi J, Matcher SJ, MacNeil S & Sangwan VS (2016) System for tracking transplanted limbal epithelial stem cells in the treatment of corneal stem cell deficiency (Conference Presentation). Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues IX, 13 February 2016 - 18 February 2016. RIS download Bibtex download
  • Boadi J, Byers RA, Fernandes J, Mittar S, Hearnden V, Lu Z, MacNeil S, Thornhill M, Murdoch C, Hunter KD , McKechnie A et al (2016) 1300 nm and 890 nm OCT images of oral cancer tissue engineered models and biopsy samples offer complimentary performance (Conference Presentation). Photonic Therapeutics and Diagnostics XII, 13 February 2016 - 18 February 2016. RIS download Bibtex download
  • Narice B, Green N, MacNeil S & Anumba D (2016) The Use of Second-Harmonic-Generation (SHG) to Assess the Impact of Menopause on the Orientation of Collagen Fibres in the Human Cervix.. REPRODUCTIVE SCIENCES, Vol. 23 (pp 214A-214A) RIS download Bibtex download
  • Raza A, Colley H, Baggaley E, Green N, Botchway S, Weinstein J, MacNeil S & Haycock J (2016) Optical measurement of oxygen concentration in melanoma spheroid and skin engineered models. European Cells and Materials (ECM), Vol. Collection 5 (pp 8-8) RIS download Bibtex download
  • Pashneh-Tala S, MacNeil S & Claeyssens F (2015) Developing a Degradable Polymer Scaffold for Vascular Graft Tissue Engineering using a Novel Photocurable Poly(glycerol Sebacate). TISSUE ENGINEERING PART A, Vol. 21 (pp S182-S182) RIS download Bibtex download
  • Shahbuddin M, Bullock A, Rimmer S & MacNeil S (2015) Physiological and Biological Effects of Konjac Glucomannan Hydrogels on Human Tissue Engineered Skin. TISSUE ENGINEERING PART A, Vol. 21 (pp S304-S304) RIS download Bibtex download
  • MacNeil S, Hillary CJ, Bullock AJ & Chapple CR (2015) Estradiol Releasing Scaffolds for the Treatment of Pelvic Floor Disorders. TISSUE ENGINEERING PART A, Vol. 21 (pp S202-S202) RIS download Bibtex download
  • MacNeil S, Mangera A, Bullock AJ, Patterson J, Osman N & Chapple C (2015) Nine Year Follow Up on Tissue Engineered Buccal Mucosa used for Urethroplasty - What have we Learnt?. TISSUE ENGINEERING PART A, Vol. 21 (pp S34-S34) RIS download Bibtex download
  • MacNeil S, Hillary CJ, Roman S, Bullock AJ & Chapple CJ (2015) Composite Materials for Pelvic Floor Repair Which Cope with Dynamic Distension and Support Cell Integration. TISSUE ENGINEERING PART A, Vol. 21 (pp S215-S215) RIS download Bibtex download
  • Dew L, Ortega I, Kelly A, Claeyssens F & MacNeil S (2015) Development of a Three-Dimensional In Vitro Model to Study Neovascularization. TISSUE ENGINEERING PART A, Vol. 21 (pp S325-S326) RIS download Bibtex download
  • Roman S, Hillary C, Urbankova I, Callewaert G, Lesage F, Deprest J, Chapple C & MacNeil S (2015) THE IN VIVO RESPONSE TO IMPLANTABLE ENGINEERED REPAIR MATERIALS DESIGNED FOR PELVIC FLOOR RECONSTRUCTION. NEUROUROLOGY AND URODYNAMICS, Vol. 34 (pp S289-S290) RIS download Bibtex download
  • Hillary C, Roman S, Bullock A, Chapple C & MacNeil S (2015) RESPONSE OF SCAFFOLD MATERIALS DESIGNED FOR TREATMENT OF STRESS URINARY INCONTINENCE (SUI) AND PELVIC ORGAN PROLAPSE (POP) TO DISTENSION. NEUROUROLOGY AND URODYNAMICS, Vol. 34 (pp S291-S292) RIS download Bibtex download
  • Pinnock A, Shivshetty N, Roy S, Rimmer S, Douglas I, MacNeil S & Garg P (2015) Models of microbial keratitis in ex vivo rabbit and human corneas. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol. 56(7) RIS download Bibtex download
  • Boadi J, Sangwal V, MacNeil S & Matcher SJ (2015) System for tracking transplanted limbal epithelial stem cells in the treatment of corneal stem cell deficiency. Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XIII RIS download Bibtex download
  • Rimmer S, Kelly L, Platt L, Gilmore L & MacNeil S (2014) Polymer colloids for the controlled elease of heparin binding growth factors. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 248 RIS download Bibtex download
  • Rimmer S, Teratanatorn P, Shepherd J, MacNeil S, Douglas I & Hoskins R (2014) Poly(N-isopropyl acrylamide) responsive to the presence of bacteria. Abstracts of papers of the American Chemical Society, Vol. 248, 10 August 2014 - 14 August 2014. RIS download Bibtex download
  • Raza A, Colley H, Baggaley E, Botchway S, Macneil S, Weinstein J & Haycock J (2014) Oxygen difference in live melanoma muticellular tumour spheroids using novel platinum compound and time-resolved imaging microscopy. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, Vol. 8 (pp 314-314) RIS download Bibtex download
  • Ortega AI, MacNeil S, Crawford A, Hatton P & Claeyssens F (2014) Microfabrication of artificial stem cell microenvironments for tissue regeneration. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, Vol. 8 (pp 175-176) RIS download Bibtex download
  • Bostan LE, Lewis R, Carre MJ, MacNeil S & Franklin SE (2014) Studies on the Friction Coefficient of Human Skin and Skin Substitutes. Proceedings of International Conference on Biotribology (ICoBT) RIS download Bibtex download
  • Osman I, Roman S, Bullock AJ, Sefat F, Chapple CR & MacNeil S (2014) Improving elastogenesis in a tissue engineered repair material for pelvic floor surgery. BRITISH JOURNAL OF SURGERY, Vol. 101 (pp 60-60) RIS download Bibtex download
  • Ramachandran C, Ortega I, Sefat F, Deshpande P, Claeyssens F, Ryan AJ, Balasubramanian D, Sangwan VS & Macneil S (2014) Microfabricated niches for the culture of limbal epithelial cells. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol. 55(13) RIS download Bibtex download
  • Osman I, Roman S, GIgliobianco G, Bullock AJ, Chapple C & MacNeil S (2013) Biomechanical optimisation of a tissue engineered prosthesis for pelvic floor repair. BRITISH JOURNAL OF SURGERY, Vol. 100 (pp 66-66) RIS download Bibtex download
  • Jiang D, Qi Y, Sindrilaru A, Walker N, Hainzl A, MacNeil S & Scharffetter-Kochanek K (2013) Safe, efficient and painless delivery of MSCs from a chemically defined carrier accelerating murine full-thickness wounds. EXPERIMENTAL DERMATOLOGY, Vol. 22(3) (pp E45-E45) RIS download Bibtex download
  • Sefat F, McKean R, Deshpande P, Ramachandran C, Hill CJ, Sangwan VS, Ryan AJ & MacNeil S (2013) Production, sterilisation and storage of biodegradable electrospun PLGA membranes for delivery of limbal stem cells to the cornea. 3RD INTERNATIONAL CONFERENCE ON TISSUE ENGINEERING (ICTE2013), Vol. 59 (pp 101-116) RIS download Bibtex download
  • Green NH, Nicholls Z, Heath PR, Highley JR, Cooper-Knock J, Corfe BM, Wilson JH, Rattray M, Liu X, MacNeil S & Bury JP (2012) Barrett's Metaplasia: Exploiting a Tissue-engineered Model to Understand the Response of the Oesophageal Squamous Mucosa to Bile and Acid Exposure. JOURNAL OF PATHOLOGY, Vol. 228 (pp S3-S3) RIS download Bibtex download
  • Puwanun S, Bye F, Delaine-Smith RM, Yates J, MacNeil S & Reilly GC (2012) Optimizing cell sources for cleft palate repair. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, Vol. 6 (pp 4-4) RIS download Bibtex download
  • Regueros RS, Mangera A, Osman N, Bullock AJ, Capple CR & MacNeil S (2012) DEVELOPING AN AUTOLOGOUS ENGINEERED CONNECTIVE TISSUE USING A BIODEGRADABLE SCAFFOLD FOR THE TREATMENT OF STRESS URINARY INCONTINENCE AND PELVIC ORGAN PROLAPSE. NEUROUROLOGY AND URODYNAMICS, Vol. 31(6) (pp 917-919) RIS download Bibtex download
  • Hearnden V, Rehman IU, MacNeil S, Murdoch C, Thornhill MH, Hunter K & Colley HE (2012) Investigation of Raman Spectroscopy and Optical Coherence Tomography to Aid in Diagnosis of Oral Cancer. EUROPEAN JOURNAL OF CANCER, Vol. 48 (pp S287-S287) RIS download Bibtex download
  • Mangera A, Roman S, Bullock A, Chapple CR & MacNeil S (2012) Assessment of a variable stress rig to improve the properties of a tissue engineered prosthesis for use in stress urinary incontinence and pelvic organ prolapse. BRITISH JOURNAL OF SURGERY, Vol. 99 (pp 58-59) RIS download Bibtex download
  • Mangera A, Bullock AJ, MacNeil S & Chapple CR (2011) Engineering a novel tissue engineered autologus prosthesis for use in stress urinary incontinence (SUI) and pelvic organ prolapse (POP) repair. BRITISH JOURNAL OF SURGERY, Vol. 98(6) (pp E6-E6) RIS download Bibtex download
  • Mangera A, Bullock AJ, MacNeil S & Chapple CR (2011) Increasing collagen production and contraction with ascorbate in a tissue engineered autologus prosthesis for use in the treatment of stress urinary incontinence (SUI) and pelvic organ prolapse (POP). BRITISH JOURNAL OF SURGERY, Vol. 98(6) (pp E7-E7) RIS download Bibtex download
  • Mangera A, Bullock AJ, MacNeil S & Chapple CR (2011) Creating a tissue engineered prosthesis for stress urinary incontinence and pelvic organ prolapse, which scaffold?. BRITISH JOURNAL OF SURGERY, Vol. 98 (pp 4-5) RIS download Bibtex download
  • Bullock AJ, Mangera A, MacNeil S & Chapple CR (2011) Development of aseptically produced scaffolds for substitution urethroplasty. BRITISH JOURNAL OF SURGERY, Vol. 98 (pp 54-54) RIS download Bibtex download
  • Bye F, Puwanun S, Reilly G & MacNeil S (2011) Using a tissue engineering approach for the treatment of cleft palate. European Cells and Materials, Vol. 22(SUPPL.3) (pp 6) RIS download Bibtex download
  • Delaine-Smith RM, Reilly G & MacNeil S (2011) Response of dermal fibroblasts to dynamic tensile loading. European Cells and Materials, Vol. 22(SUPPL.2) (pp 41) RIS download Bibtex download
  • Dario P, Verschure PFMJ, Prescott T, Cheng G, Sandini G, Cingolani R, Dillmann R, Floreano D, Leroux C, MacNeil S , Roelfsema P et al (2011) Robot companions for citizens. Procedia Computer Science, Vol. 7 (pp 47-51) View this article in WRRO RIS download Bibtex download
  • Mangera A, Bullock A, MacNeil S & Chapple CR (2011) COMPARATIVE INVESTIGATION OF SEVEN CANDIDATE SCAFFOLDS FOR THE PRODUCTION OF AN AUTOLOGOUS TISSUE ENGINEERED CONNECTIVE TISSUE FOR USE IN STRESS URINARY INCONTINENCE AND PELVIC ORGAN PROLAPSE. NEUROUROLOGY AND URODYNAMICS, Vol. 30(6) (pp 868-870) RIS download Bibtex download
  • Green N, Haque A, Corfe B, MacNeil S & Bury J (2010) Invasive behaviour of the OE33 oesophageal adenocarcinoma cell line is dependent on co-operation with fibroblasts.. JOURNAL OF PATHOLOGY, Vol. 222 (pp S43-S43) RIS download Bibtex download
  • Hearnden V, Smith L, Colley H, Thornhill M, Murdoch C, Smallwood R, Matcher S & MacNeil S (2010) Using tissue-engineered oral cancer models to evaluate non-invasive diagnostic technologies. ORAL DIS, Vol. 16(6) (pp 518-518) RIS download Bibtex download
  • Mangera A, Bullock AJ, MacNeil S & Chapple C (2010) DEVELOPING AN AUTOLOGOUS TISSUE ENGINEERED PROSTHESIS FOR USE IN STRESS URINARY INCONTINENCE AND PELVIC ORGAN PROLAPSE. NEUROUROLOGY AND URODYNAMICS, Vol. 29(6) (pp 1129-1130) RIS download Bibtex download
  • Murdoch C, Colley H, MacNeil S & Thornhill M (2009) Hypoxia-induced secretion of CXCL12 by head and neck tumour spheroids mediates infiltration of monocytes by a CXCR4-dependent mechanism. ORAL ONCOLOGY (pp 68-68) RIS download Bibtex download
  • Colley HE, MacNeil S, Jones AV, Thornhill MH & Murdoch C (2009) The development of in vitro models of squamous cell carcinoma of the oral mucosa - From mild dysplasia to an expanding carcinoma. ORAL ONCOLOGY (pp 160-160) RIS download Bibtex download
  • Hearnden V, Battaglia G, MacNeil S, Murdoch C & Thornhill M (2009) Penetration of polymersome drug and gene delivery nanoparticles into in vitro models of head and neck cancer and tissue engineered oral mucosa. ORAL ONCOLOGY (pp 66-66) RIS download Bibtex download
  • Moustafa M, Carr J, Longton C, Clarke J, MacNeil S & Cork M (2009) Management of a chronic vasculitic leg ulcer with systemic immunosuppressant therapy and autologous keratinocyte cell spray. BRITISH JOURNAL OF DERMATOLOGY, Vol. 161 (pp 124-124) RIS download Bibtex download
  • Walter MNM, MacNeil S & Johnson WEB (2009) Investigations of cell-cell and cell-matrix interaction in skin wound repair using the scratch assay. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, Vol. 90(2) (pp A134-A134) RIS download Bibtex download
  • Hogg RA, Greenwood PDL, Childs DTD, Krstajic N, Kennedy K, Groom KM, Hugues M, Hopkinson M, Smith LE, Matcher SJ , Bonesi M et al (2009) GaAs Based Quantum Dot Superluminescent Diodes for Optical Coherence Tomography of Skin Tissue. 2009 4TH INTERNATIONAL CONFERENCE ON COMPUTERS AND DEVICES FOR COMMUNICATION (CODEC 2009) (pp 426-431) RIS download Bibtex download
  • Krstajic N, Smallwood R, Childs DTD, Greenwood PDL, Hugues M, Kennedy K, Hopkinson M, Groom KM, Hogg RA, Smith LE , Matcher SJ et al (2009) Optical coherence tomography with high power quantum-dot superluminescent diodes. 2009 IEEE LEOS ANNUAL MEETING CONFERENCE PROCEEDINGS, VOLS 1AND 2 (pp 207-208) RIS download Bibtex download
  • Hearnden V, Battaglia G, Murdoch C, Thornhill M & MacNeil S (2008) Imaging of polymersome penetration into 3D tissue engineered models of oral mucosa and head and neck cancer. European Cells and Materials, Vol. 16(SUPPL. 3) (pp 58) RIS download Bibtex download
  • Deshpande P, Bullett N, Notara M, Daniels JT, Haddow D & MacNeil S (2007) Use of a rabbit cornea model for the development of a cell transfer system for limbal epithelial cells. TISSUE ENGINEERING, Vol. 13(7) (pp 1773-1773) RIS download Bibtex download
  • Murray-Dunning C, Sane N, McKean R, MacNeil S, Ryan A & Haycock JW (2007) Use of aligned polymer microfibres for peripheral nerve repair. TISSUE ENGINEERING, Vol. 13(7) (pp 1774-1774) RIS download Bibtex download
  • Harrison CA, Thornton DJ & MacNeil S (2007) Use of tissue-engineered skin to enhance understanding of skin graft contraction. TISSUE ENGINEERING, Vol. 13(7) (pp 1774-1774) RIS download Bibtex download
  • MacNeil S, Redpath M, Waddon A, Lalla R & Marques CMG (2007) Ibuprofen and hydrogel released ibuprofen in the reduction of inflammation induced migration in melanoma cells. TISSUE ENGINEERING, Vol. 13(7) (pp 1708-1709) RIS download Bibtex download
  • Eves P, Bullett N, Haddow D, Gawkrodger D & MacNeil S (2007) Improved technologies for translating culture of human melanocytes to the clinic. TISSUE ENGINEERING, Vol. 13(7) (pp 1711-1711) RIS download Bibtex download
  • Perlin L, Rimmer S & MacNeil S (2007) Cell culture on RGD-containing hydrogels. TISSUE ENGINEERING, Vol. 13(7) (pp 1649-1649) RIS download Bibtex download
  • Blackwood K, Freeman CO, McKean R, Farthing P, Haycock JW, Ryan AJ, Brook I & MacNeil S (2007) Development of biocompatible, biodegradable electrospun scaffolds for tissue engineering of human skin. TISSUE ENGINEERING, Vol. 13(7) (pp 1670-1671) RIS download Bibtex download
  • MacNeil S (2007) Use of biomaterials in the regeneration of skin. TISSUE ENGINEERING, Vol. 13(4) (pp 875-875) RIS download Bibtex download
  • Sun Y, Maughan J, Haigh R, Hopkins SA, Wyman P, Johnson C, Fullwood NJ, Ebdon J, MacNeil S & Rimmer S (2007) Polymethacrylate networks as substrates for cell culture. MACROMOLECULAR SYMPOSIA, Vol. 256 (pp 137-148) RIS download Bibtex download
  • Haddow D, Short R, MacNeil S, Jarmolowicz M, Moustafa M & Hernon C (2006) Delivering cell therapy for chronic wounds. Medical Textiles and Biomaterials for Healthcare (pp 476-481) RIS download Bibtex download
  • Sun Y, MacNeil S & Rimmer S (2005) Amphiphilic poly (glycerol methacrylate-block-butyl methacrylate) copolymer networks: Synthesis and biointeractions. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 230 (pp U1218-U1218) RIS download Bibtex download
  • Eves P, Beck AJ, Shard AG & Macneil S (2005) Melanocyte and keratinocyte culture on plasma polymers for the treatment of patients with vitiligo. BRITISH JOURNAL OF DERMATOLOGY, Vol. 152(4) (pp 856-857) RIS download Bibtex download
  • Boult JKR, Bury JP, Bullock AJ, Campbell MJ, Taniere P, MacNeil S & Tselepis C (2005) Regulation of the MYC network in the progression to oesophageal adenocarcinoma. GUT, Vol. 54 (pp A87-A87) RIS download Bibtex download
  • Haycock JW, Hill RP, Elliott RJ, Wagner MJ & MacNeil S (2004) Antioxidant and anti-inflammatory activities of melanocortin peptides. EXPERIMENTAL DERMATOLOGY, Vol. 13(9) (pp 576-576) RIS download Bibtex download
  • Katerinaki E, Lalla R, Haycock JW, Lorigan PC & MacNeil S (2004) Sodium salicylate inhibits inflammation induced invasion and migration of human melanoma cells. BRITISH JOURNAL OF CANCER, Vol. 91 (pp S71-S71) RIS download Bibtex download
  • Bhargava S, Chapple CR, Bullock AJ & MacNeil S (2004) Development and characterisation of tissue-engineered buccal mucosa for urethroplasty. JOURNAL OF UROLOGY, Vol. 171(4) (pp 18-18) RIS download Bibtex download
  • Katerinaki E, Evans G, Lorigan P & MacNeil S (2003) TNF-alpha increases human melanoma cell invasion and migration in vitro - The role of proteolytic enzymes. BRITISH JOURNAL OF CANCER, Vol. 88 (pp S66-S66) RIS download Bibtex download
  • Smith-Thomas LC, Moustafa M, Spada CS, Shi L, Balafa C, Wagner M, Reagan J, Krauss A, Woodward D & MacNeil S (2003) Latanoprost-induced pigmentation in human iridial melanocytes is fibroblast dependent. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol. 44 (pp U517-U517) RIS download Bibtex download
  • Haddow DB, France RM, Short RD, MacNeil S & Dawson RA (1999) Comparison of proliferation and growth of human keratinocytes on plasma co-polymers of acrylic acid/1,7-octadiene and self assembled monolayers. PLASMA DEPOSITION AND TREATMENT OF POLYMERS, Vol. 544 (pp 39-44) RIS download Bibtex download
  • MACNEIL S, BUFFEY J, HILL SE, DOBSON J & BLEEHEN SS (1992) INTRACELLULAR SIGNALING IN THE CONTROL OF MELANOGENESIS. PIGMENT CELL RESEARCH (pp 154-161) RIS download Bibtex download
  • Crawford A, MacNeil S & Amirrasooli H (1981) A soluble endogenous regulator of adenylate cyclase. Biochemical Society Transactions, Vol. 9(2) RIS download Bibtex download
  • OLLIS CA, MACNEIL S, CRAWFORD A, CHIVERS L, HUMPHRIES H, MUNRO DS & TOMLINSON S (1981) SIMILARITY OF HUMAN THYROID ADENYLATE-CYCLASE RESPONSE TO THYROTROPIN (TSH) AND THYROID STIMULATING IMMUNOGLOBULINS (TSIG). CLIN SCI, Vol. 60(3) (pp P10-P10) RIS download Bibtex download
  • OLLIS C, MACNEIL S, CRAWFORD A, MUNRO DS & TOMLINSON S (1980) ACTIVATION OF HUMAN THYROID MEMBRANE ADENYLATE-CYCLASE BY THYROID-STIMULATING IMMUNOGLOBULINS REQUIRES THE PRESENCE OF A FACTOR PRESENT IN THE CELL CYTOSOL. J ENDOCRINOL, Vol. 85(2) (pp P27-P28) RIS download Bibtex download
  • CRAWFORD A, MACNEIL S & MARTIN TJ (1979) ADENYLATE-CYCLASE ACTIVATING FACTOR IN CYTOSOL OF RAT OSTEOGENIC-SARCOMA. J ENDOCRINOL, Vol. 81(2) (pp P151-P152) RIS download Bibtex download
  • Krstajić N, Jacobs J, Bonesi M, Smith LE, Deshpande P, MacNeil S, Smallwood R & Matcher SJ () Ex vivo and in vivo OCT image contrast. Proceedings of SPIE - The International Society for Optical Engineering, Vol. 7139. 2008, 8 September 2008 - 10 September 2008. RIS download Bibtex download
Research group

Supervision of 2 to 3 honours project students per year for 30 credit BEng (MAT356) and 60 credit (MAT404) research projects.

Supervision of 2 MSc students per year for Biomaterials and Regenerative Medicine.

Teaching activities

MAT300/MAT407 (20 credits) – Tissue Engineering
FCE101 (20 credits) - An Introduction to Bioengineering.
FCE201 (10 credits) - Advanced Bioengineering Topics

Professional activities
  • Awarded the President's Prize from UK Society for Biomaterials in recognition of long standing service to biomaterials science both in the UK and internationally (2014)
  • Member of EPSRC Peer Review College (2010 onwards)
  • Member of UK Tissue and Cell Engineering Society (TCES) (2009 onwards)
  • Member of Swiss National Science Foundation NRP 63 - Stem Cells and Regenerative Medicine (2008 onwards)
  • NC3R Grant Reviewing Panel (2008 - 2011)
  • MRC Small Grant Reviewing Panel (2006-2007)
  • Member of EPSRC Grant Reviewing College (2003-2006)
  • Member of BBSRC Engineering and Biological Systems Panel (2000-2003)
  • Member of MRC Regenerative Medicine Research Committee
Women in Engineering

We interviewed Sheila for the Faculty of Engineering's Wall of Women when she was Professor of Tissue Engineering. Here are Sheila's interviews:

The Wall of Women profiles were taken over a 4/5 year time period and are a snapshot of what our engineers were doing at that time.