Professor Sheila MacNeil

BSc (Hons), PhD

Department of Materials Science and Engineering

Emeritus Professor

Professor of Biomaterials and Tissue Engineering

Professor Sheila MacNeil
Profile

Sheila is Emeritus Professor of Tissue Engineering with expertise in tissue engineering of soft tissues (skin, oral mucosa, urethra and cornea) with a focus on translating research to the clinic. She has over 550 peer-reviewed articles and an h-index of 57.

Since 1992 she has worked with clinicians in Sheffield, delivering autologous keratinocytes to burns patients and developed and commercialised improved delivery of skin cells to patients with MySkin™ and Cryoskin™ (autologous and allogeneic cell therapy for wound healing). In the last decade she has focussed on three translational project areas. The first with NHS Urologist Professor Chris Chapple in Sheffield to develop tissue engineered oral mucosa for reconstruction of urethral strictures and to develop alternative materials for support of the weakened tissues of the pelvic floor. The second project is developing cell delivery membranes for corneal defects working with colleagues in India. The third project is developing novel biomaterials to promote angiogenesis in chronic wounds working with Dr Muhammed Yar in Pakistan.

The research collaboration with India has led to a simplification in the treatment of corneal scarring which has reduced the cost by 90% and most importantly increased accessibility of this technique to patients. This has led to a change in clinical practice in India and has attracted considerable publicity.

She received the UK Society of Biomaterials President’s medal for her contributions to Biomaterials in both the UK and overseas in September 2014 and the Institute of Materials, Minerals and Mining (IOM3) Chapman Medal for Biomedical Materials and Biomaterials Innovation in 2018.

Sheila retired in September 2018 but remains research active.

Qualifications

BSc (Hons) Physiology, Aberdeen University 1972

PhD, Physiology, Sheffield University 1976

Research interests

Sheila’s research currently spans four interdisciplinary themes:

  1. 3D in vitro models of skin, oral mucosa, cornea and vagina
    The group has a 20 year history of developing 3D models of soft tissue to look at a range of problems including wound healing, angiogenesis and bacterial infection.
    The skin model is currently used to study skin contraction in adult and paediatric burns patients using autologous fat.
  2. Developing cell delivery membranes for corneal defects working with colleagues in India
    The most recent outcome of this research has led to a significant improvement in how patients receive treatment for corneal scarring – the new simplified technique is more accessible to more patients and only costs 10% of the previous technique. News story.
  3. Developing alternative materials for support of the weakened tissues of the pelvic floor
    This project has led to patented technology now licenced to a spin out company Symimetics. Work is ongoing to develop material into a device for a first in women study for the surgical treatment of stress urinary incontinence.
  4. Developing novel biomaterials to promote angiogenesis in chronic wounds
    Working with Dr Muhammed Yar in Pakistan to deliver a 2dDRribose sugar capable of inducing angiogenesis and promoting wound healing.
Publications

Journal articles

Chapters

Conference proceedings papers

  • Murray K, MacNeil S & Spain S (2019) Development of a topical prodrug to treat burn scar contracture. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 257 RIS download Bibtex download
  • Dikici S, Mangir N, Kanczler J, Yar M, Oreffo R & MacNeil S (2018) Evaluation of the angiogenic and osteogenic activity of two potent alternatives to VEGF: 2-deoxy-D-ribose (2dDR) and 17 beta-Estradiol (E2) loaded tissue engineering scaffolds. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 256 RIS download Bibtex download
  • Roman S, Mangir N, Hympanova L, Deprest J, Chapple CR & MacNeil S (2018) USE OF ACCELERATED FATIGUE TESTING AS A SIMPLE IN VITRO TEST FOR ASSESSING MATERIALS FOR THE SURGICAL TREATMENT OF STRESS URINARY INCONTINENCE AND PELVIC ORGAN PROLAPSE. NEUROUROLOGY AND URODYNAMICS, Vol. 37 (pp S379-S380) RIS download Bibtex download
  • Pashneh-Tala S, Sherborne C, MacNeil S & Claeyssens F (2017) Tissue-Engineered Blood Vessels with User-Defined Geometries. TISSUE ENGINEERING PART A, Vol. 23 (pp S140-S140) RIS download Bibtex download
  • Hympanova L, Cunha M, Rynkevic R, Roman S, Gallego M, Vange J, Wach RA, Callewaert G, Urbankova I, Van der Aa F , Macneil S et al (2017) COMPARABLE VAGINALWALL BIOMECHANICAL PROPERTIES FOLLOWING ELECTROSPUN POLYCARBONATE- UREIDOPYRIMIDONE MESH IMPLANTATION AND SIMULATED NATIVE TISSUE REPAIR IN SHEEP. INTERNATIONAL UROGYNECOLOGY JOURNAL, Vol. 28 (pp S37-S38) RIS download Bibtex download
  • Doroshenko N, Rimmer S, Foster S, MacNeil S & Douglas I (2017) Corneal infections: targeted eradication through antibiotic functionalized polymers. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol. 58(8) RIS download Bibtex download
  • Boadi J, Matcher SJ, MacNeil S & Sangwan VS (2016) System for tracking transplanted limbal epithelial stem cells in the treatment of corneal stem cell deficiency (Conference Presentation). Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues IX, 13 February 2016 - 18 February 2016. RIS download Bibtex download
  • Boadi J, Byers RA, Fernandes J, Mittar S, Hearnden V, Lu Z, MacNeil S, Thornhill M, Murdoch C, Hunter KD , McKechnie A et al (2016) 1300 nm and 890 nm OCT images of oral cancer tissue engineered models and biopsy samples offer complimentary performance (Conference Presentation). Photonic Therapeutics and Diagnostics XII, 13 February 2016 - 18 February 2016. RIS download Bibtex download
  • Narice B, Green N, MacNeil S & Anumba D (2016) The Use of Second-Harmonic-Generation (SHG) to Assess the Impact of Menopause on the Orientation of Collagen Fibres in the Human Cervix.. REPRODUCTIVE SCIENCES, Vol. 23 (pp 214A-214A) RIS download Bibtex download
  • Raza A, Colley H, Baggaley E, Green N, Botchway S, Weinstein J, MacNeil S & Haycock J (2016) Optical measurement of oxygen concentration in melanoma spheroid and skin engineered models. European Cells and Materials (ECM), Vol. Collection 5 (pp 8-8) RIS download Bibtex download
  • Pashneh-Tala S, MacNeil S & Claeyssens F (2015) Developing a Degradable Polymer Scaffold for Vascular Graft Tissue Engineering using a Novel Photocurable Poly(glycerol Sebacate). TISSUE ENGINEERING PART A, Vol. 21 (pp S182-S182) RIS download Bibtex download
  • Shahbuddin M, Bullock A, Rimmer S & MacNeil S (2015) Physiological and Biological Effects of Konjac Glucomannan Hydrogels on Human Tissue Engineered Skin. TISSUE ENGINEERING PART A, Vol. 21 (pp S304-S304) RIS download Bibtex download
  • MacNeil S, Hillary CJ, Bullock AJ & Chapple CR (2015) Estradiol Releasing Scaffolds for the Treatment of Pelvic Floor Disorders. TISSUE ENGINEERING PART A, Vol. 21 (pp S202-S202) RIS download Bibtex download
  • MacNeil S, Mangera A, Bullock AJ, Patterson J, Osman N & Chapple C (2015) Nine Year Follow Up on Tissue Engineered Buccal Mucosa used for Urethroplasty - What have we Learnt?. TISSUE ENGINEERING PART A, Vol. 21 (pp S34-S34) RIS download Bibtex download
  • MacNeil S, Hillary CJ, Roman S, Bullock AJ & Chapple CJ (2015) Composite Materials for Pelvic Floor Repair Which Cope with Dynamic Distension and Support Cell Integration. TISSUE ENGINEERING PART A, Vol. 21 (pp S215-S215) RIS download Bibtex download
  • Dew L, Ortega I, Kelly A, Claeyssens F & MacNeil S (2015) Development of a Three-Dimensional In Vitro Model to Study Neovascularization. TISSUE ENGINEERING PART A, Vol. 21 (pp S325-S326) RIS download Bibtex download
  • Hillary C, Roman S, Bullock A, Chapple C & MacNeil S (2015) RESPONSE OF SCAFFOLD MATERIALS DESIGNED FOR TREATMENT OF STRESS URINARY INCONTINENCE (SUI) AND PELVIC ORGAN PROLAPSE (POP) TO DISTENSION. NEUROUROLOGY AND URODYNAMICS, Vol. 34 (pp S291-S292) RIS download Bibtex download
  • Roman S, Hillary C, Urbankova I, Callewaert G, Lesage F, Deprest J, Chapple C & MacNeil S (2015) THE IN VIVO RESPONSE TO IMPLANTABLE ENGINEERED REPAIR MATERIALS DESIGNED FOR PELVIC FLOOR RECONSTRUCTION. NEUROUROLOGY AND URODYNAMICS, Vol. 34 (pp S289-S290) RIS download Bibtex download
  • Pinnock A, Shivshetty N, Roy S, Rimmer S, Douglas I, MacNeil S & Garg P (2015) Models of microbial keratitis in ex vivo rabbit and human corneas. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol. 56(7) RIS download Bibtex download
  • Boadi J, Sangwal V, MacNeil S & Matcher SJ (2015) System for tracking transplanted limbal epithelial stem cells in the treatment of corneal stem cell deficiency. Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XIII RIS download Bibtex download
  • Rimmer S, Kelly L, Platt L, Gilmore L & MacNeil S (2014) Polymer colloids for the controlled elease of heparin binding growth factors. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 248 RIS download Bibtex download
  • Rimmer S, Teratanatorn P, Shepherd J, MacNeil S, Douglas I & Hoskins R (2014) Poly(N-isopropyl acrylamide) responsive to the presence of bacteria. Abstracts of papers of the American Chemical Society, Vol. 248, 10 August 2014 - 14 August 2014. RIS download Bibtex download
  • Ortega AI, MacNeil S, Crawford A, Hatton P & Claeyssens F (2014) Microfabrication of artificial stem cell microenvironments for tissue regeneration. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, Vol. 8 (pp 175-176) RIS download Bibtex download
  • Raza A, Colley H, Baggaley E, Botchway S, Macneil S, Weinstein J & Haycock J (2014) Oxygen difference in live melanoma muticellular tumour spheroids using novel platinum compound and time-resolved imaging microscopy. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, Vol. 8 (pp 314-314) RIS download Bibtex download
  • Bostan LE, Lewis R, Carre MJ, MacNeil S & Franklin SE (2014) Studies on the Friction Coefficient of Human Skin and Skin Substitutes. Proceedings of International Conference on Biotribology (ICoBT) RIS download Bibtex download
  • Osman I, Roman S, Bullock AJ, Sefat F, Chapple CR & MacNeil S (2014) Improving elastogenesis in a tissue engineered repair material for pelvic floor surgery. BRITISH JOURNAL OF SURGERY, Vol. 101 (pp 60-60) RIS download Bibtex download
  • Ramachandran C, Ortega I, Sefat F, Deshpande P, Claeyssens F, Ryan AJ, Balasubramanian D, Sangwan VS & Macneil S (2014) Microfabricated niches for the culture of limbal epithelial cells. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol. 55(13) RIS download Bibtex download
  • Osman I, Roman S, GIgliobianco G, Bullock AJ, Chapple C & MacNeil S (2013) Biomechanical optimisation of a tissue engineered prosthesis for pelvic floor repair. BRITISH JOURNAL OF SURGERY, Vol. 100 (pp 66-66) RIS download Bibtex download
  • Jiang D, Qi Y, Sindrilaru A, Walker N, Hainzl A, MacNeil S & Scharffetter-Kochanek K (2013) Safe, efficient and painless delivery of MSCs from a chemically defined carrier accelerating murine full-thickness wounds. EXPERIMENTAL DERMATOLOGY, Vol. 22(3) (pp E45-E45) RIS download Bibtex download
  • Sefat F, McKean R, Deshpande P, Ramachandran C, Hill CJ, Sangwan VS, Ryan AJ & MacNeil S (2013) Production, sterilisation and storage of biodegradable electrospun PLGA membranes for delivery of limbal stem cells to the cornea. 3RD INTERNATIONAL CONFERENCE ON TISSUE ENGINEERING (ICTE2013), Vol. 59 (pp 101-116) RIS download Bibtex download
  • Green NH, Nicholls Z, Heath PR, Highley JR, Cooper-Knock J, Corfe BM, Wilson JH, Rattray M, Liu X, MacNeil S & Bury JP (2012) Barrett's Metaplasia: Exploiting a Tissue-engineered Model to Understand the Response of the Oesophageal Squamous Mucosa to Bile and Acid Exposure. JOURNAL OF PATHOLOGY, Vol. 228 (pp S3-S3) RIS download Bibtex download
  • Puwanun S, Bye F, Delaine-Smith RM, Yates J, MacNeil S & Reilly GC (2012) Optimizing cell sources for cleft palate repair. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, Vol. 6 (pp 4-4) RIS download Bibtex download
  • Regueros RS, Mangera A, Osman N, Bullock AJ, Capple CR & MacNeil S (2012) DEVELOPING AN AUTOLOGOUS ENGINEERED CONNECTIVE TISSUE USING A BIODEGRADABLE SCAFFOLD FOR THE TREATMENT OF STRESS URINARY INCONTINENCE AND PELVIC ORGAN PROLAPSE. NEUROUROLOGY AND URODYNAMICS, Vol. 31(6) (pp 917-919) RIS download Bibtex download
  • Hearnden V, Rehman IU, MacNeil S, Murdoch C, Thornhill MH, Hunter K & Colley HE (2012) Investigation of Raman Spectroscopy and Optical Coherence Tomography to Aid in Diagnosis of Oral Cancer. EUROPEAN JOURNAL OF CANCER, Vol. 48 (pp S287-S287) RIS download Bibtex download
  • Mangera A, Roman S, Bullock A, Chapple CR & MacNeil S (2012) Assessment of a variable stress rig to improve the properties of a tissue engineered prosthesis for use in stress urinary incontinence and pelvic organ prolapse. BRITISH JOURNAL OF SURGERY, Vol. 99 (pp 58-59) RIS download Bibtex download
  • Mangera A, Bullock AJ, MacNeil S & Chapple CR (2011) Increasing collagen production and contraction with ascorbate in a tissue engineered autologus prosthesis for use in the treatment of stress urinary incontinence (SUI) and pelvic organ prolapse (POP). BRITISH JOURNAL OF SURGERY, Vol. 98(6) (pp E7-E7) RIS download Bibtex download
  • Mangera A, Bullock AJ, MacNeil S & Chapple CR (2011) Engineering a novel tissue engineered autologus prosthesis for use in stress urinary incontinence (SUI) and pelvic organ prolapse (POP) repair. BRITISH JOURNAL OF SURGERY, Vol. 98(6) (pp E6-E6) RIS download Bibtex download
  • Mangera A, Bullock AJ, MacNeil S & Chapple CR (2011) Creating a tissue engineered prosthesis for stress urinary incontinence and pelvic organ prolapse, which scaffold?. BRITISH JOURNAL OF SURGERY, Vol. 98 (pp 4-5) RIS download Bibtex download
  • Bullock AJ, Mangera A, MacNeil S & Chapple CR (2011) Development of aseptically produced scaffolds for substitution urethroplasty. BRITISH JOURNAL OF SURGERY, Vol. 98 (pp 54-54) RIS download Bibtex download
  • Delaine-Smith RM, Reilly G & MacNeil S (2011) Response of dermal fibroblasts to dynamic tensile loading. European Cells and Materials, Vol. 22(SUPPL.2) (pp 41) RIS download Bibtex download
  • Bye F, Puwanun S, Reilly G & MacNeil S (2011) Using a tissue engineering approach for the treatment of cleft palate. European Cells and Materials, Vol. 22(SUPPL.3) (pp 6) RIS download Bibtex download
  • Dario P, Verschure PFMJ, Prescott T, Cheng G, Sandini G, Cingolani R, Dillmann R, Floreano D, Leroux C, MacNeil S , Roelfsema P et al (2011) Robot companions for citizens. Procedia Computer Science, Vol. 7 (pp 47-51) View this article in WRRO RIS download Bibtex download
  • Mangera A, Bullock A, MacNeil S & Chapple CR (2011) COMPARATIVE INVESTIGATION OF SEVEN CANDIDATE SCAFFOLDS FOR THE PRODUCTION OF AN AUTOLOGOUS TISSUE ENGINEERED CONNECTIVE TISSUE FOR USE IN STRESS URINARY INCONTINENCE AND PELVIC ORGAN PROLAPSE. NEUROUROLOGY AND URODYNAMICS, Vol. 30(6) (pp 868-870) RIS download Bibtex download
  • Green N, Haque A, Corfe B, MacNeil S & Bury J (2010) Invasive behaviour of the OE33 oesophageal adenocarcinoma cell line is dependent on co-operation with fibroblasts.. JOURNAL OF PATHOLOGY, Vol. 222 (pp S43-S43) RIS download Bibtex download
  • Hearnden V, Smith L, Colley H, Thornhill M, Murdoch C, Smallwood R, Matcher S & MacNeil S (2010) Using tissue-engineered oral cancer models to evaluate non-invasive diagnostic technologies. ORAL DIS, Vol. 16(6) (pp 518-518) RIS download Bibtex download
  • Mangera A, Bullock AJ, MacNeil S & Chapple C (2010) DEVELOPING AN AUTOLOGOUS TISSUE ENGINEERED PROSTHESIS FOR USE IN STRESS URINARY INCONTINENCE AND PELVIC ORGAN PROLAPSE. NEUROUROLOGY AND URODYNAMICS, Vol. 29(6) (pp 1129-1130) RIS download Bibtex download
  • Murdoch C, Colley H, MacNeil S & Thornhill M (2009) Hypoxia-induced secretion of CXCL12 by head and neck tumour spheroids mediates infiltration of monocytes by a CXCR4-dependent mechanism. ORAL ONCOLOGY (pp 68-68) RIS download Bibtex download
  • Colley HE, MacNeil S, Jones AV, Thornhill MH & Murdoch C (2009) The development of in vitro models of squamous cell carcinoma of the oral mucosa - From mild dysplasia to an expanding carcinoma. ORAL ONCOLOGY (pp 160-160) RIS download Bibtex download
  • Moustafa M, Carr J, Longton C, Clarke J, MacNeil S & Cork M (2009) Management of a chronic vasculitic leg ulcer with systemic immunosuppressant therapy and autologous keratinocyte cell spray. BRITISH JOURNAL OF DERMATOLOGY, Vol. 161 (pp 124-124) RIS download Bibtex download
  • Hearnden V, Battaglia G, MacNeil S, Murdoch C & Thornhill M (2009) Penetration of polymersome drug and gene delivery nanoparticles into in vitro models of head and neck cancer and tissue engineered oral mucosa. ORAL ONCOLOGY (pp 66-66) RIS download Bibtex download
  • Walter MNM, MacNeil S & Johnson WEB (2009) Investigations of cell-cell and cell-matrix interaction in skin wound repair using the scratch assay. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, Vol. 90(2) (pp A134-A134) RIS download Bibtex download
  • Hogg RA, Greenwood PDL, Childs DTD, Krstajic N, Kennedy K, Groom KM, Hugues M, Hopkinson M, Smith LE, Matcher SJ , Bonesi M et al (2009) GaAs Based Quantum Dot Superluminescent Diodes for Optical Coherence Tomography of Skin Tissue. 2009 4TH INTERNATIONAL CONFERENCE ON COMPUTERS AND DEVICES FOR COMMUNICATION (CODEC 2009) (pp 426-431) RIS download Bibtex download
  • Krstajic N, Smallwood R, Childs DTD, Greenwood PDL, Hugues M, Kennedy K, Hopkinson M, Groom KM, Hogg RA, Smith LE , Matcher SJ et al (2009) Optical coherence tomography with high power quantum-dot superluminescent diodes. 2009 IEEE LEOS ANNUAL MEETING CONFERENCE PROCEEDINGS, VOLS 1AND 2 (pp 207-208) RIS download Bibtex download
  • Hearnden V, Battaglia G, Murdoch C, Thornhill M & MacNeil S (2008) Imaging of polymersome penetration into 3D tissue engineered models of oral mucosa and head and neck cancer. European Cells and Materials, Vol. 16(SUPPL. 3) (pp 58) RIS download Bibtex download
  • Murray-Dunning C, Sane N, McKean R, MacNeil S, Ryan A & Haycock JW (2007) Use of aligned polymer microfibres for peripheral nerve repair. TISSUE ENGINEERING, Vol. 13(7) (pp 1774-1774) RIS download Bibtex download
  • Harrison CA, Thornton DJ & MacNeil S (2007) Use of tissue-engineered skin to enhance understanding of skin graft contraction. TISSUE ENGINEERING, Vol. 13(7) (pp 1774-1774) RIS download Bibtex download
  • Eves P, Bullett N, Haddow D, Gawkrodger D & MacNeil S (2007) Improved technologies for translating culture of human melanocytes to the clinic. TISSUE ENGINEERING, Vol. 13(7) (pp 1711-1711) RIS download Bibtex download
  • Deshpande P, Bullett N, Notara M, Daniels JT, Haddow D & MacNeil S (2007) Use of a rabbit cornea model for the development of a cell transfer system for limbal epithelial cells. TISSUE ENGINEERING, Vol. 13(7) (pp 1773-1773) RIS download Bibtex download
  • Perlin L, Rimmer S & MacNeil S (2007) Cell culture on RGD-containing hydrogels. TISSUE ENGINEERING, Vol. 13(7) (pp 1649-1649) RIS download Bibtex download
  • Blackwood K, Freeman CO, McKean R, Farthing P, Haycock JW, Ryan AJ, Brook I & MacNeil S (2007) Development of biocompatible, biodegradable electrospun scaffolds for tissue engineering of human skin. TISSUE ENGINEERING, Vol. 13(7) (pp 1670-1671) RIS download Bibtex download
  • MacNeil S, Redpath M, Waddon A, Lalla R & Marques CMG (2007) Ibuprofen and hydrogel released ibuprofen in the reduction of inflammation induced migration in melanoma cells. TISSUE ENGINEERING, Vol. 13(7) (pp 1708-1709) RIS download Bibtex download
  • MacNeil S (2007) Use of biomaterials in the regeneration of skin. TISSUE ENGINEERING, Vol. 13(4) (pp 875-875) RIS download Bibtex download
  • Sun Y, Maughan J, Haigh R, Hopkins SA, Wyman P, Johnson C, Fullwood NJ, Ebdon J, MacNeil S & Rimmer S (2007) Polymethacrylate networks as substrates for cell culture. MACROMOLECULAR SYMPOSIA, Vol. 256 (pp 137-148) RIS download Bibtex download
  • Haddow D, Short R, MacNeil S, Jarmolowicz M, Moustafa M & Hernon C (2006) Delivering cell therapy for chronic wounds. Medical Textiles and Biomaterials for Healthcare (pp 476-481) RIS download Bibtex download
  • Sun Y, MacNeil S & Rimmer S (2005) Amphiphilic poly (glycerol methacrylate-block-butyl methacrylate) copolymer networks: Synthesis and biointeractions. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 230 (pp U1218-U1218) RIS download Bibtex download
  • Eves P, Beck AJ, Shard AG & Macneil S (2005) Melanocyte and keratinocyte culture on plasma polymers for the treatment of patients with vitiligo. BRITISH JOURNAL OF DERMATOLOGY, Vol. 152(4) (pp 856-857) RIS download Bibtex download
  • Boult JKR, Bury JP, Bullock AJ, Campbell MJ, Taniere P, MacNeil S & Tselepis C (2005) Regulation of the MYC network in the progression to oesophageal adenocarcinoma. GUT, Vol. 54 (pp A87-A87) RIS download Bibtex download
  • Haycock JW, Hill RP, Elliott RJ, Wagner MJ & MacNeil S (2004) Antioxidant and anti-inflammatory activities of melanocortin peptides. EXPERIMENTAL DERMATOLOGY, Vol. 13(9) (pp 576-576) RIS download Bibtex download
  • Katerinaki E, Lalla R, Haycock JW, Lorigan PC & MacNeil S (2004) Sodium salicylate inhibits inflammation induced invasion and migration of human melanoma cells. BRITISH JOURNAL OF CANCER, Vol. 91 (pp S71-S71) RIS download Bibtex download
  • Bhargava S, Chapple CR, Bullock AJ & MacNeil S (2004) Development and characterisation of tissue-engineered buccal mucosa for urethroplasty. JOURNAL OF UROLOGY, Vol. 171(4) (pp 18-18) RIS download Bibtex download
  • Katerinaki E, Evans G, Lorigan P & MacNeil S (2003) TNF-alpha increases human melanoma cell invasion and migration in vitro - The role of proteolytic enzymes. BRITISH JOURNAL OF CANCER, Vol. 88 (pp S66-S66) RIS download Bibtex download
  • Smith-Thomas LC, Moustafa M, Spada CS, Shi L, Balafa C, Wagner M, Reagan J, Krauss A, Woodward D & MacNeil S (2003) Latanoprost-induced pigmentation in human iridial melanocytes is fibroblast dependent. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol. 44 (pp U517-U517) RIS download Bibtex download
  • Haddow DB, France RM, Short RD, MacNeil S & Dawson RA (1999) Comparison of proliferation and growth of human keratinocytes on plasma co-polymers of acrylic acid/1,7-octadiene and self assembled monolayers. PLASMA DEPOSITION AND TREATMENT OF POLYMERS, Vol. 544 (pp 39-44) RIS download Bibtex download
  • MACNEIL S, BUFFEY J, HILL SE, DOBSON J & BLEEHEN SS (1992) INTRACELLULAR SIGNALING IN THE CONTROL OF MELANOGENESIS. PIGMENT CELL RESEARCH (pp 154-161) RIS download Bibtex download
  • Crawford A, MacNeil S & Amirrasooli H (1981) A soluble endogenous regulator of adenylate cyclase. Biochemical Society Transactions, Vol. 9(2) RIS download Bibtex download
  • OLLIS CA, MACNEIL S, CRAWFORD A, CHIVERS L, HUMPHRIES H, MUNRO DS & TOMLINSON S (1981) SIMILARITY OF HUMAN THYROID ADENYLATE-CYCLASE RESPONSE TO THYROTROPIN (TSH) AND THYROID STIMULATING IMMUNOGLOBULINS (TSIG). CLIN SCI, Vol. 60(3) (pp P10-P10) RIS download Bibtex download
  • OLLIS C, MACNEIL S, CRAWFORD A, MUNRO DS & TOMLINSON S (1980) ACTIVATION OF HUMAN THYROID MEMBRANE ADENYLATE-CYCLASE BY THYROID-STIMULATING IMMUNOGLOBULINS REQUIRES THE PRESENCE OF A FACTOR PRESENT IN THE CELL CYTOSOL. J ENDOCRINOL, Vol. 85(2) (pp P27-P28) RIS download Bibtex download
  • CRAWFORD A, MACNEIL S & MARTIN TJ (1979) ADENYLATE-CYCLASE ACTIVATING FACTOR IN CYTOSOL OF RAT OSTEOGENIC-SARCOMA. J ENDOCRINOL, Vol. 81(2) (pp P151-P152) RIS download Bibtex download
  • Workman V, Penuelas A, Higginbotham S, Roman S, Giblin V, MacNeil S, Green N & Hearnden V () There’s more to fat than stem cells, characterising fat graft materials to understand the regenerative properties of adipose tissues. eCM Meeting Abstracts 2020, Collection 1, Vol. Collection 1(2020 TERMIS EU) (pp 158-158) RIS download Bibtex download
  • Krstajić N, Jacobs J, Bonesi M, Smith LE, Deshpande P, MacNeil S, Smallwood R & Matcher SJ () Ex vivo and in vivo OCT image contrast. Proceedings of SPIE - The International Society for Optical Engineering, Vol. 7139. 2008, 8 September 2008 - 10 September 2008. RIS download Bibtex download
Grants
Professional activities
  • Awarded the Institute of Materials, Minerals and Mining (IOM3) Chapman Medal for Biomedical Materials and Biomaterials Innovation (2018).
  • Awarded the President's Prize from UK Society for Biomaterials in recognition of long standing service to biomaterials science both in the UK and internationally (2014)
  • Member of EPSRC Peer Review College (2010 onwards)
  • Member of UK Tissue and Cell Engineering Society (TCES) (2009 onwards)
  • Member of Swiss National Science Foundation NRP 63 - Stem Cells and Regenerative Medicine (2008 onwards)
  • NC3R Grant Reviewing Panel (2008 - 2011)
  • MRC Small Grant Reviewing Panel (2006-2007)
  • Member of EPSRC Grant Reviewing College (2003-2006)
  • Member of BBSRC Engineering and Biological Systems Panel (2000-2003)
  • Member of MRC Regenerative Medicine Research Committee
Women in Engineering

We interviewed Sheila for the Faculty of Engineering's Wall of Women when she was Professor of Tissue Engineering. Here are Sheila's interviews:

The Wall of Women profiles were taken over a 4/5 year time period and are a snapshot of what our engineers were doing at that time.