As a result of the Covid-19 pandemic vaccination processes have undergone a major shift. You can be a part of that transformation if you study with us here at Sheffield. Study your PhD with us in the department of Chemical and Biological Engineering and you could help develop platform solutions to overcome future global pandemics and help solve other wickedly world diseases.
Here at Sheffield you'll develop digital tools for driving the development and operation of RNA vaccine and therapeutics production processes for enabling rapid, high volume, low-cost and high-quality vaccine and therapeutics production. Study with us and you could literally change millions of lives.
Data-Driven Modelling and Optimisation of mRNA Vaccine Manufacture
We invite applications for a 3.5 year funded PhD studentship to work under the supervision of Dr Solomon Brown. We are working on an impactful, fast-paced and exciting project aiming to innovate RNA production processes for therapy and pandemic preparedness. The RNA vaccine platform technology has been successfully used to develop COVID-19 vaccines at record speeds. Although this first iteration of RNA vaccines was clinically successful, there is still substantial room for improving the production processes to increase production rates and volumes, and to reduce costs, whilst maintaining consistently high product quality. The demand for RNA production capacity is projected to increase given the success and platform nature of this technology. Besides COVID-19 vaccines, the mRNA platform technology is in prime position to promote rapid development and mass-production of mRNA vaccines against seasonal influenza with much shorter timelines, Rabies, Zika, Human Papilloma Virus, Hepatitis C, Malaria, HIV, immune disorders, cancer as well as against currently unknown, future viral targets. There is substantial room to develop computational models, digitise and automate the RNA platform technology for speeding up product-process development, enhancing production rates and production volumes, reducing costs and assuring high product quality.
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Development of Analytical Methods for the Analysis of mRNA Vaccines and Therapeutics
We invite applications for a 3.5 year funded PhD studentship to work under the supervision of Professor Mark Dickman. We are working on an impactful, fast-paced and exciting project aiming to innovate RNA production processes for therapy and pandemic preparedness. The RNA vaccine platform technology has been successfully used to develop COVID-19 vaccines at record speeds. Although this first iteration of RNA vaccines was clinically successful, there is still substantial room for improving the production processes to increase production rates and volumes, and to reduce costs, whilst maintaining consistently high product quality. The demand for RNA production capacity is projected to increase given the success and platform nature of this technology. Besides COVID-19 vaccines, the mRNA platform technology is in prime position to promote rapid development and mass-production of mRNA vaccines against seasonal influenza with much shorter timelines, Rabies, Zika, Human Papilloma Virus, Hepatitis C, Malaria, HIV, immune disorders, cancer as well as against currently unknown, future viral targets. To enable this product and process development, it is crucial to develop new and improved analytical methods for the characterization of RNA quality for vaccinology and therapeutic applications.
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Development and Innovation of mRNA Vaccine & Therapeutic Production Processes
We're invite applications for a 3.5 year funded PhD studentship to work under the supervision of Dr Zoltán Kis at the University of Sheffield. We are working on an impactful, fast-paced and exciting project aiming to innovate RNA production processes for therapy and pandemic preparedness.
The RNA vaccine platform technology has been successfully used to develop COVID-19 vaccines at record speeds. Although this first iteration of RNA vaccines was clinically successful, there is still substantial room for improving the production processes, i.e. to increase production rates and volumes, and to reduce costs, whilst maintaining consistently high product quality. The demand for RNA production capacity is projected to increase given the success and platform nature of this technology. Besides COVID-19 vaccines, the RNA platform technology is in prime position to promote rapid development and mass-production of vaccines against seasonal influenza, Rabies, Zika, Human Papilloma Virus, Hepatitis C, Malaria, HIV, immune disorders and cancer as well as against currently unknown, future viral targets. A key limitation for unleashing the full potential of this transformative platform technology is the availability to manufacture RNA vaccines and therapeutics rapidly, at high volumes, at low-cost and at high-quality.
More information and apply now
Data-Analytics/Visualisation Platform for mRNA Manufacturing
We invite applications for a 3.5 year funded PhD studentship to work under the supervision of Dr Peyman Z. Moghadam. We are working on an impactful, fast-paced and exciting project aiming to innovate RNA production processes. The RNA vaccine platform technology has been successfully used to develop COVID-19 vaccines at record speeds. Although this first iteration of RNA vaccines was clinically successful, there is still substantial room for improving the production processes to increase production rates and volumes, and to reduce costs, whilst maintaining consistently high product quality. The demand for RNA production capacity is projected to increase given the success and platform nature of this technology. Besides COVID-19 vaccines, the mRNA platform technology is in prime position to promote rapid development and mass-production of mRNA vaccines against seasonal influenza with much shorter timelines, Rabies, Zika, Human Papilloma Virus, Hepatitis C, Malaria, HIV, immune disorders, cancer as well as against currently unknown, future viral targets. There is substantial room to develop digital tools for analysing and visualising big data from the RNA platform production technology, to allow better and more user-friendly process monitoring, understanding and operation.