Dr Nicola Green

PhD FRMS

Biomedical engineering

Department of Materials Science and Engineering

Senior Lecturer in Bioengineering

Course Director for Bioengineering

Dr Nicola Green, profile image
Profile picture of Dr Nicola Green, profile image
n.h.green@sheffield.ac.uk
+44 114 222 3932

Full contact details

Dr Nicola Green
Biomedical engineering
North Campus
Broad Lane
Sheffield
S3 7HQ
Profile

Nicola is a Senior Lecturer in Bioengineering. She obtained her first degree from the University of Nottingham and her PhD from the University of Kent. She has worked as a Research Fellow at the University of Nottingham, in the Laboratory of Biophysics and Surface Analysis, and as a Senior Scientist in a Nottingham University biomedical spin-off company.

She joined the department in 2006 as a postdoctoral researcher, before taking charge of the Kroto Imaging Facility as Experimental Officer in 2010. She was appointed as Lecturer in Bioengineering in 2019 and Senior Lecturer in 2022.

Qualifications

1998 PhD – Biotechnology, University of Kent

1992 – BSc Hons Biochemistry and Genetics, Nottingham University

Research interests

Nicola’s interdisciplinary research focuses biomaterials and tissue engineering. Her portfolio can be divided into three key areas

Biohybrid scaffolds for tissue engineering: Scaffolds which incorporate biological components into synthetic scaffolds combine benefits from both and have significant clinical potential. This research seeks to optimise the composition and manufacture of these scaffolds to create tuneable scaffolds with enhanced cellular responses and reduced immunogenicity.

Improved in vitro models: The development and use of in vitro 3D models for improved drug discovery and to more reliably model disease progression including cancer invasion and metastasis, wound healing, and the musculoskeletal system.

Imaging of biomaterials and tissues: Development and application of non-invasive imagine techniques to better characterise biomaterials and the cellular response.

Publications

Journal articles

Chapters

  • Green N & Haycock JW (2016) Fluorescence Microscopy, Optical Techniques in Regenerative Medicine (pp. 29-59). RIS download Bibtex download
  • Green N & Haycock JW (2013) Fluorescence Microscopy In Morgan S, Rose FR & Matcher SJ (Ed.), Optical Techniques in Regenerative Medicine (pp. 29-59). Boca Raton: Taylor & Francis. RIS download Bibtex download

Conference proceedings papers

  • Jackson CE, Green N, English W, Bryant HE & Claeyssens F (2023) Production of porous polycaprolactone polyHIPEs as substrates for in vitro 3D breast cancer cell culture. TISSUE ENGINEERING PART A, Vol. 29(13-14) RIS download Bibtex download
  • Thanarak J, Damian D, Claeyssens F & Green N (2023) OPTIMISING THE FABRICATION, SURFACE TREATMENT AND MECHANICAL STIMULATION TO IMPROVE THE CELL PROLIFERATION AND COLLAGEN PRODUCTION FROM PRIMARY DERMAL FIBROBLASTS IN VITRO. TISSUE ENGINEERING PART A, Vol. 29(11-12) (pp 1150-1151) RIS download Bibtex download
  • Hann A, Reilly GC, Green NH, Claeyssens F & Tetteh G (2023) MCSS SUPPORT A LAMELLA-LIKE TWISTING ORIENTATION OF COLLAGEN WHEN CULTURED ON ALIGNED ELECTROSPUN POLYCAPROLACTONE FIBRES. TISSUE ENGINEERING PART A, Vol. 29(11-12) (pp 1586-1587) RIS download Bibtex download
  • Cebe T, Balasubramanian M, Green N & Reilly G (2023) ELUCIDATION OF COLLAGEN FIBRE STRUCTURE IN OSTEOGENESIS IMPERFECTA USING SECOND HARMONIC GENERATION IMAGING ON POLYCAPROLACTONE FIBRES. TISSUE ENGINEERING PART A, Vol. 29(11-12) (pp 953-953) RIS download Bibtex download
  • Suvarna MV, Crawford A, Reilly GC, Claeyssens F & Green NH (2023) Development of an in vitro musculoskeletal model using poly (glycerol sebacate methacrylate) (PGSM) polyHIPE-based 3D microporous scaffold encompassing regionally controlled mechanical properties. TISSUE ENGINEERING PART A, Vol. 29(13-14) RIS download Bibtex download
  • Liu B, Green N, Rodenburg C & Claeyssens F (2023) Developing Biodegradable Polymer Resins for Additive Manufacturing via a Novel Synthesis Method. TISSUE ENGINEERING PART A, Vol. 29(13-14) RIS download Bibtex download
  • Chauhan R, Aleemardani M, Green NH & Claeyssens F (2023) A digital reconstruction of the dermal-epidermal junction (DEJ) of the skin in three dimensions. TISSUE ENGINEERING PART A, Vol. 29(13-14) RIS download Bibtex download
  • Suvarna MV, Crawford A, Reilly GC, Claeyssens F & Green NH (2023) Development of an in vitro musculoskeletal model using poly (glycerol sebacate methacrylate) (PGSM) polyHIPE-based 3D microporous scaffold encompassing regionally controlled mechanical properties. TISSUE ENGINEERING PART A, Vol. 29(13-14) RIS download Bibtex download
  • Aleemardani M, Trikic MZ, Green NH & Claeyssens F (2023) Development and characterisation of new bioelastomers based on poly(glycerol sebacate)-copolyethylene glycol for biomedical applications. TISSUE ENGINEERING PART A, Vol. 29(13-14) RIS download Bibtex download
  • Chauhan R, Aleemardani M, Green NH & Claeyssens F (2023) A digital reconstruction of the dermal-epidermal junction (DEJ) of the skin in three dimensions. TISSUE ENGINEERING PART A, Vol. 29(13-14) RIS download Bibtex download
  • Cebe T, Balasubramanian M, Green N & Reilly G (2022) Abstract 2122: Visualization of collagen fibre structure in osteogenesis imperfecta using second harmonic generation imaging on polycaprolactone scaffold. Tissue Engineering Part A, Vol. 28(S1) (pp S601-S602). Maastricht, Netherlands, 15 November 2021 - 15 November 2021. View this article in WRRO RIS download Bibtex download
  • Workman VL, Higginbotham SJ, Roman S, Penuelas AA, Giblin V, MacNeil S, Green N & Hearnden V (2022) THERE'S MORE TO FAT THAN STEM CELLS, CHARACTERISING FAT GRAFT MATERIALS TO UNDERSTAND THE REGENERATIVE PROPERTIES OF ADIPOSE TISSUES. TISSUE ENGINEERING PART A, Vol. 28 (pp S544-S544) RIS download Bibtex download
  • Thanarak J, Mohammed H, Pashneh-Tala S, Claeyssens F & Green N (2018) Enhanced Collagen Production from Human Dermal Fibroblasts on Poly(glycerol sebacate)-methacrylate Scaffolds. 2018 11th Biomedical Engineering International Conference (BMEiCON), 21 November 2018 - 24 November 2018. View this article in WRRO RIS download Bibtex download
  • Narice B, Green N, MacNeil S & Anumba D (2016) The Use of Second-Harmonic-Generation (SHG) to Assess the Impact of Menopause on the Orientation of Collagen Fibres in the Human Cervix.. REPRODUCTIVE SCIENCES, Vol. 23 (pp 214A-214A) RIS download Bibtex download
  • Tetteh G, Delaine-Smith R, Green N & Reilly G (2016) Collagen and Mineral Deposition by MLO-A5 Late-Stage Osteoblasts, is Guided by the Fibre Alignment of Electrospun Scaffolds. Proceedings of the 22nd Congress of the European Society of Biomechanics, 10 July 2016 - 13 July 2016. RIS download Bibtex download
  • Raza A, Colley H, Baggaley E, Green N, Botchway S, Weinstein J, MacNeil S & Haycock J (2016) Optical measurement of oxygen concentration in melanoma spheroid and skin engineered models. European Cells and Materials (ECM), Vol. Collection 5 (pp 8-8) RIS download Bibtex download
  • Paterson TE, Dugan JM, Sherborne C, Green NH, Reilly GC & Claeyssens F (2015) Highly Porous Particles for Cell Recruitment and Delivery in Bone Tissue Engineering. TISSUE ENGINEERING PART A, Vol. 21 (pp S287-S288) RIS download Bibtex download
  • Green NH, Nicholls Z, Heath PR, Highley JR, Cooper-Knock J, Corfe BM, Wilson JH, Rattray M, Liu X, MacNeil S & Bury JP (2012) Barrett's Metaplasia: Exploiting a Tissue-engineered Model to Understand the Response of the Oesophageal Squamous Mucosa to Bile and Acid Exposure. JOURNAL OF PATHOLOGY, Vol. 228 (pp S3-S3) RIS download Bibtex download
  • Fish KE, Sharpe RL, Green NH, Osborn M & Boxall JB (2011) Visualising and quantifying the matrix of drinking water biofilms. IWA Biofilms 2011. Shanghai, China, 27 October 2011 - 30 October 2011. RIS download Bibtex download
  • Green N, Haque A, Corfe B, MacNeil S & Bury J (2010) Invasive behaviour of the OE33 oesophageal adenocarcinoma cell line is dependent on co-operation with fibroblasts.. JOURNAL OF PATHOLOGY, Vol. 222 (pp S43-S43) RIS download Bibtex download
  • Nicholls Z, Green NH, Corfe BM, MacNeil S & Bury JP (2010) Taurochenodeoxycholic acid activates NF-KB in oesophageal squamous cells without accompanying loss in cell viability. Journal of Pathology, Vol. 220(S1) (pp S11-S11) RIS download Bibtex download
Research group

PhD students

Main Supervisor

  • Jeerawan Thanarak
  • Meghna Suvarna

Co-supervisor

  • Samuel Higginbotham
  • Tugba Cebe
  • Alice Hann
  • Boyang Liu
  • Abigail Smith
  • Mina Aleemardani
  • Jonathan Hinchliffe
  • Caitlin Jackson
Grants
  • Multi-materials additive manufacturing for musculoskeletal applications (principal investigator, Royal Society International Exchanges, £12,000)
  • Reversing skin contraction in paediatric burns patients (co-investigator, Sheffield Hospitals Charity, £426,288)
  • Transforming metalorganic frameworks promoted bone regeneration through secondary electron hyperspectral imaging (co-investigator, Newton Mobility Grant, £11,930)
Teaching interests

Nicola contributes to learning and teaching within the Department of Materials Science and Engineering and the Faculty of Engineering. She teaches on a number of modules based on her research interests which are taken by both Bioengineering in Interdisciplinary Engineering, and Materials Science and Engineering students.

Teaching activities
  • Biology and Chemistry of Living Systems II (MAT2530)
  • Bioimaging (MAT408/6311, Module lead) - fourth year/MSc module.

She also is module lead for BIE103 and BIE201, two courses taken by Bioengineering students which demonstrate the breadth of the Bioengineering field and introduce students to key technical, practical and professional skills within Bioengineering.