Dr Nicola Green

PhD FRMS

Department of Materials Science and Engineering

Lecturer in Bioengineering

Dr Nicola Green, profile image
n.h.green@sheffield.ac.uk
+44 114 222 3932

Full contact details

Dr Nicola Green
Department of Materials Science and Engineering
North Campus
Broad Lane
Sheffield
S3 7HQ
Profile

Nicola is a Lecturer in Bioengineering. She obtained her first degree from the University of Nottingham and her PhD from the University of Kent. She has worked as a Research Fellow at the University of Nottingham, in the Laboratory of Biophysics and Surface Analysis, and as a Senior Scientist in a Nottingham University biomedical spin-off company.

She joined the department in 2006 as a postdoctoral researcher, working with Prof Sheila MacNeil on the development of a tissue-engineered model of the human oesophageal mucosa, before taking charge of the Kroto Imaging Facility as Experimental Officer in 2010. She was appointed as Research Fellow in 2014 and Lecturer in Bioengineering in 2019.

She has been Admissions Tutor for Bioengineering since 2017 and continues to support the Imaging Facility.

Qualifications

1998 PhD – Biotechnology, University of Kent

1992 – BSc Hons Biochemistry and Genetics, Nottingham University

Research interests

Nicola’s interdisciplinary research focuses on tissue engineering of soft tissues, with particular emphasis upon the oesophagus, for both translation to the clinic and as more biologically-relevant experimental models for use in the laboratory.

She also has interests in developing novel imaging methods and applying established imaging techniques to the field of tissue engineering, for improved characterization of cell growth and behaviour in 3D cultures throughout the culture period.

Current research projects include the use of novel DNA probes for imaging cells and the use of second-harmonic generation imaging collagen formation in tissue-engineered constructs.

  • Oeosphageal cancer/ Barrett’s Oeosphagus
  • Tissue Engineering
  • Bioimaging
Publications

Journal articles

Chapters

  • Green N & Haycock JW (2013) Fluorescence Microscopy In Morgan S, Rose FR & Matcher SJ (Ed.), Optical Techniques in Regenerative Medicine (pp. 29-59). Boca Raton: Taylor & Francis. RIS download Bibtex download

Conference proceedings papers

  • Thanarak J, Mohammed H, Pashneh-Tala S, Claeyssens F & Green N (2018) Enhanced Collagen Production from Human Dermal Fibroblasts on Poly(glycerol sebacate)-methacrylate Scaffolds. 2018 11th Biomedical Engineering International Conference (BMEiCON), 21 November 2018 - 24 November 2018. View this article in WRRO RIS download Bibtex download
  • Narice B, Green N, MacNeil S & Anumba D (2016) The Use of Second-Harmonic-Generation (SHG) to Assess the Impact of Menopause on the Orientation of Collagen Fibres in the Human Cervix.. REPRODUCTIVE SCIENCES, Vol. 23 (pp 214A-214A) RIS download Bibtex download
  • Tetteh G, Delaine-Smith R, Green N & Reilly G (2016) Collagen and Mineral Deposition by MLO-A5 Late-Stage Osteoblasts, is Guided by the Fibre Alignment of Electrospun Scaffolds. Proceedings of the 22nd Congress of the European Society of Biomechanics, 10 July 2016 - 13 July 2016. RIS download Bibtex download
  • Raza A, Colley H, Baggaley E, Green N, Botchway S, Weinstein J, MacNeil S & Haycock J (2016) Optical measurement of oxygen concentration in melanoma spheroid and skin engineered models. European Cells and Materials (ECM), Vol. Collection 5 (pp 8-8) RIS download Bibtex download
  • Paterson TE, Dugan JM, Sherborne C, Green NH, Reilly GC & Claeyssens F (2015) Highly Porous Particles for Cell Recruitment and Delivery in Bone Tissue Engineering. TISSUE ENGINEERING PART A, Vol. 21 (pp S287-S288) RIS download Bibtex download
  • Green NH, Nicholls Z, Heath PR, Highley JR, Cooper-Knock J, Corfe BM, Wilson JH, Rattray M, Liu X, MacNeil S & Bury JP (2012) Barrett's Metaplasia: Exploiting a Tissue-engineered Model to Understand the Response of the Oesophageal Squamous Mucosa to Bile and Acid Exposure. JOURNAL OF PATHOLOGY, Vol. 228 (pp S3-S3) RIS download Bibtex download
  • Fish KE, Sharpe RL, Green NH, Osborn M & Boxall JB (2011) Visualising and quantifying the matrix of drinking water biofilms. IWA Biofilms 2011. Shanghai, China, 27 October 2011 - 30 October 2011. RIS download Bibtex download
  • Green N, Haque A, Corfe B, MacNeil S & Bury J (2010) Invasive behaviour of the OE33 oesophageal adenocarcinoma cell line is dependent on co-operation with fibroblasts.. JOURNAL OF PATHOLOGY, Vol. 222 (pp S43-S43) RIS download Bibtex download
  • Nicholls Z, Green NH, Corfe BM, MacNeil S & Bury JP (2010) Taurochenodeoxycholic acid activates NF-KB in oesophageal squamous cells without accompanying loss in cell viability. Journal of Pathology, Vol. 220(S1) (pp S11-S11) RIS download Bibtex download
Research group

Main Supervisor (PhD Student)

  • Jeerawan Thanarak (PhD Student)

Co-supervisor (PhD Students)

  • Samuel Higginbotham
  • Nicholas Farr
  • Tugba Cebe
  • Alice Hann
  • Boyang Liu
  • Abigail Smith

MSc Students

  • Amber Cairney-Witter
  • Jonathan Hinchliffe

Undergraduate Project Students

  • Eleanor Pressdee
  • Changhavi Ragurajan
  • Ella Ball
  • Isobel May-Smith
  • Jillian Hoderial
  • Christoforos Savvidis
Grants
  • Multi-materials additive manufacturing for musculoskeletal applications (principal investigator, Royal Society International Exchanges, £12,000)
  • Reversing skin contraction in paediatric burns patients (co-investigator, Sheffield Hospitals Charity, £426,288)
  • Transforming metalorganic frameworks promoted bone regeneration through secondary electron hyperspectral imaging (co-investigator, Newton Mobility Grant, £11,930)
Teaching interests

Nicola contributes to learning and teaching within the Department of Materials Science and Engineering and the Faculty of Engineering. She teaches on a number of modules based on her research interests which are taken by both Bioengineering in Interdisciplinary Engineering, and Materials Science and Engineering students.

Teaching activities
  • Biology and Chemistry of Living Systems I (MAT1520, Module lead)
  • Biology and Chemistry of Living Systems II (MAT2530)
  • Bioimaging (MAT408/6311, Module lead) - fourth year/MSc module.

She also is module lead for BIE103 and BIE201, two courses taken by Bioengineering students which aim to demonstrate the breadth of the Bioengineering field and introduce students to key technical and professional skills within Bioengineering.