Dr Laura Saunders

All publications

Journal articles

• Wild JM, Gleeson FV, Svenningsen S, Grist JT, Saunders LC, Collier GJ, Sharma M, Tcherner S, Mozaffaripour A, Matheson AM & Parraga G (2024) Review of Hyperpolarized Pulmonary Functional ¹²⁹Xe MR for Long‐COVID. Journal of Magnetic Resonance Imaging, 59(4).
• Elneima O, McAuley HJC, Leavy OC, Chalmers JD, Horsley A, Ho L-P, Marks M, Poinasamy K, Raman B, Shikotra A , Singapuri A et al (2023) Cohort profile: post-hospitalisation COVID-19 (PHOSP-COVID) study. International Journal of Epidemiology. View this article in WRRO
• Baillie JK, Lone NI, Jones S, Shaw A, Hairsine B, Kurasz C, Henson H, Armstrong L, Shenton L, Dobson H , Dell A et al (2023) Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study. The Lancet Respiratory Medicine.
• Astley JR, Biancardi AM, Marshall H, Smith LJ, Hughes PJC, Collier GJ, Saunders LC, Norquay G, Tofan M-M, Hatton MQ , Hughes R et al (2023) PhysVENeT: a physiologically-informed deep learning-based framework for the synthesis of 3D hyperpolarized gas MRI ventilation. Scientific Reports, 13.
• Saunders LC, Collier GJ, Chan H-F, Hughes PJC, Smith LJ, Watson J, Meiring J, Gabriel Z, Newman T, Plowright M , Wade P et al (2023) Longitudinal lung function assessment of patients hospitalised with COVID-19 using 1H and 129Xe lung MRI. Chest.
• Liew F, Talwar S, Cross A, Willett BJ, Scott S, Logan N, Siggins MK, Swieboda D, Sidhu JK, Efstathiou C , Moore SC et al (2023) SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination. eBioMedicine, 87.
• Stewart I, Jacob J, George PM, Molyneaux PL, Porter JC, Allen RJ, Aslani S, Baillie JK, Barratt SL, Beirne P , Bianchi SM et al (2023) Residual lung abnormalities following COVID-19 hospitalization: interim analysis of the UKILD post-COVID study. American Journal of Respiratory and Critical Care Medicine, 207(6), 693-703.
• Dwivedi K, Condliffe R, Sharkey M, Lewis R, Alabed S, Rajaram S, Hill C, Saunders L, Metherall P, Alandejani F , Alkhanfar D et al (2022) Computed tomography lung parenchymal descriptions in routine radiological reporting have diagnostic and prognostic utility in patients with idiopathic pulmonary arterial hypertension and pulmonary hypertension associated with lung disease. ERJ Open Research, 8(1). View this article in WRRO
• Alabed S, Saunders L, Garg P, Shahin Y, Alandejani F, Rolf A, Puntmann VO, Nagel E, Wild JM, Kiely DG & Swift AJ (2021) Myocardial T1-mapping and extracellular volume in pulmonary arterial hypertension: A systematic review and meta-analysis. Magnetic Resonance Imaging, 79, 66-75.
• Saunders LC, Eaden JA, Bianchi SM, Swift AJ & Wild JM (2020) Free breathing lung T1 mapping using image registration in patients with idiopathic pulmonary fibrosis. Magnetic Resonance in Medicine, 84(6), 3088-3102. View this article in WRRO
• Saunders L, Johns C, Stewart N, Oram C, Capener D, Puntmann V, Elliot C, Condliffe R, Kiely D, Wild JM , Graves M et al (2018) Diagnostic and prognostic significance of cardiovascular magnetic resonance native myocardial T1 mapping in patients with pulmonary hypertension. Journal of Cardiovascular Magnetic Resonance, 20. View this article in WRRO
• Garg P (2018) Role of Cardiac T1 Mapping and Extracellular Volume (ECV) in the Assessment of Myocardial Infarction. The Anatolian Journal of Cardiology. View this article in WRRO
• Swift AJ, Saunders LC, Sproson T, Hussain N, Collier GJ, Marshall H, Kiely DG & Wild JM (2015) Multiparametric Magnetic Resonance Imaging in Pulmonary Hypertension. Current Cardiovascular Imaging Reports, 8(12).
• Collier GJ, Smith LJ, Saunders LC, Swift AJ, Marshall H, Stewart NJ, Norquay G, Hughes PJC, Thomspson AAR & Wild JM () Age, sex, and lung volume dependence of dissolved xenon‐129 MRI gas exchange metrics. Magnetic Resonance in Medicine.
• Wild JM, Gleeson FV, Svenningsen S, Grist JT, Saunders LC, Collier GJ, Sharma M, Tcherner S, Mozaffaripour A, Matheson AM & Parraga G () Review of Hyperpolarized Pulmonary Functional ¹²⁹Xe MR for Long‐COVID. Journal of Magnetic Resonance Imaging.
• Jackson C, Stewart ID, Plekhanova T, Cunningham PS, Hazel AL, Al-Sheklly B, Aul R, Bolton CE, Chalder T, Chalmers JD , Chaudhuri N et al () Effects of sleep disturbance on dyspnoea and impaired lung function following hospital admission due to COVID-19 in the UK: a prospective multicentre cohort study. The Lancet Respiratory Medicine.
• Astley JR, Biancardi AM, Hughes PJC, Marshall H, Collier GJ, Chan H, Saunders LC, Smith LJ, Brook ML, Thompson R , Rowland‐Jones S et al () Implementable Deep Learning for Multi‐sequence Proton MRI Lung Segmentation: A Multi‐center, Multi‐vendor, and Multi‐disease Study. Journal of Magnetic Resonance Imaging.
• Swift AJ, Wilson F, Cogliano M, Kendall L, Alandejani F, Alabed S, Hughes P, Shahin Y, Saunders L, Oram C , Capener D et al () Repeatability and sensitivity to change of non-invasive end points in PAH: the RESPIRE study. Thorax.
• Saunders LC, Hughes PJC, Alabed S, Capener DJ, Marshall H, Vogel‐Claussen J, Beek EJR, Kiely DG, Swift AJ & Wild JM () Integrated Cardiopulmonary MRI Assessment of Pulmonary Hypertension. Journal of Magnetic Resonance Imaging.

Conference proceedings papers

• Driskel M, Marshall H, Biancardi A, Smith L, Capener D, Bray J, Zalewska A, Fazal S, Saunders L, Munro R , Rodgers O et al (2024) S2 Evaluation of lung transplant function and detection of CLAD using 129Xe-MRI and LCI. ‘The Catcher in the MRI’ – Functional imaging in lung disease (pp A8-A8)
• Saunders L, Collier G, Smith L, Marshall H, Biancardi A, Swift A, Jakymelen D, Strickland S, Gustafsson L, Munro R , Stewart N et al (2024) 129Xe lung ventilation imaging in patients with long COVID without prior respiratory disease. Imaging (pp PA5251-PA5251)
• Saunders L, Hughes PJC, Ng KL, Collier GJ, Grist J, Smith LJ, Strickland S, Gustafsson L, Horsley A, Swift AJ , Fraser E et al (2024) Contrast enhanced MRI does not detect differences in pulmonary perfusion between patients with long COVID and controls. Imaging (pp PA5252-PA5252)
• Fraser E, Ng K, Saunders L, Grist J, Collier G, Strickland S, Gustafsson L, Smith L, Evans R, Vuddamalay N , Rodgers J et al (2024) HypErpolarised Xenon Magnetic Resonance PuLmonary Imaging in PAtIeNts with Long-COVID (EXPLAIN): Lung diffusion findings. Imaging (pp PA5250-PA5250)
• Ng KL, Saunders LC, Collier G, Grist J, Strickland S, Gustafsson L, Smith LJ, Hughes PJC, Kainth N, Evans RI , Laws A et al (2024) The EXPLAIN (Hyperpolarised Xenon Magnetic Resonance Pulmonary Imaging in Patients With Long-COVID) Study: The Primary Outcome. C75. STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF COVID
• Marshall H, Smith LJ, Biancardi A, Collier GJ, Chan HF, Capener D, Bray J, Jakymelen D, Saunders L, Astley J , Tahir BA et al (2023) P177 129Xe MRI phenotyping and longitudinal change in patients with asthma and/or COPD and normal pulmonary function tests. ‘You ain’t seen nothing yet’ – Imaging across COPD, nodules and lung cancer screening
• Smith LJ, Marshall H, Biancardi A, Collier GJ, Chan HF, Capener D, Bray J, Jakymelen D, Saunders L, Astley J , Tahir BA et al (2023) P176 Bronchodilator response discordance in patients with asthma and/or COPD assessed by 129Xe-MRI and spirometry. ‘You ain’t seen nothing yet’ – Imaging across COPD, nodules and lung cancer screening
• Saunders LC, Collier GJ, Smith LJ, Hughes PJC, Marshall H, Chan HF, Biancardi A, Grist J, Strickland S, Gustafsson L , Ho LP et al (2023) S19 Gas exchange imaging using dissolved-phase 129Xe MRI in post COVID cohorts. ‘Shake it off’ – Recovery from COVID-19
• Smith L, Marshall H, Biancardi A, Collier G, Chan H-F, Capener D, Bray J, Jakymelen D, Saunders L, Astley J , Tahir B et al (2023) Xe-MRI bronchodilator response to assess disease severity in patients with asthma and/or COPD. Respiratory function technologists/scientists
• Smith L, Marshall H, Biancardi A, Collier G, Chan H-F, Capener D, Bray J, Jakymelen D, Saunders L, Astley J , Tahir B et al (2023) Bronchodilator response discordance in patients with asthma and/or COPD using Xe-MRI and spirometry. Respiratory function technologists/scientists
• Marshall H, Smith L, Biancardi A, Collier G, Chan H-F, Capener D, Bray J, Jakymelen D, Saunders L, Astley J , Tahir B et al (2023) Longitudinal change in lung physiology and 129Xe MRI over 1 year in patients with asthma and/or COPD. Clinical respiratory physiology, exercise and functional imaging
• Collier G, Saunders L, Smith LJ, Ng K, Grist J, Swift AJ, Davies H, Horsley A, Thompson AAR, Fraser E , Gleeson F et al (2023) Age, sex and lung volume dependence of 129Xe MRI gas exchange metrics. Clinical respiratory physiology, exercise and functional imaging
• Ng K, Grist J, Saunders L, Collier G, Laws A, Abu Eid G, Kainth N, Strickland S, Gustafsson L, Thomas S , Dryhurst-Pearce L et al (2023) Unexplained lung function differences in dyspnoeic non-hospitalised Long-COVID (NHLC) patients and asymptomatic fully recovered COVID-19 controls - the EXPLAIN study. Clinical respiratory physiology, exercise and functional imaging
• Saunders L, Collier G, Chan H, Hughes P, Smith L, Watson J, Gabriel Z, Meiring J, Plowright M, Newman T , Eaden J et al (2022) Longitudinal lung function assessment of patients hospitalised with COVID-19 using 1H and 129Xe lung MRI. European Respiratory Society (ERS) International Congress 2022, Vol. 60(Suppl 66) (pp 760). Barcelona, Spain, 4 September 2022 - 4 September 2022.
• Saunders L, Capener D, Condliffe R, Kiely D, Wild J & Swift A (2021) MRI metric lung parenchyma T1 indicates lung pathology in patients with pulmonary hypertension. Pulmonary hypertension
• Saunders L, Eaden J, Bianchi S, Swift A & Wild J (2019) Free breathing lung MRI T1 in patients with idiopathic pulmonary fibrosis and healthy volunteers. Imaging
• Saunders L, Johns CS, Stewart N, Capener D, Kiely D, Graves M, Wild JM & Swift A (2018) Prognostic Value of T1 Mapping in Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
• Saunders L, Johns CS, Stewart N, Capener D, Kiely D, Graves M, Wild JM & Swift A (2018) Diastolic Septal Angle Is an Independent Predictor of Right Ventricular Insertion Point T1 in Pulmonary Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
• Weatherley N, Chan F, Stewart N, Saunders L, Collier G, Norquay G, Rao M, Austin M, Bianchi S & Wild J (2016) Diffusion-weighted hyperpolarised gas MRI in idiopathic pulmonary fibrosis : reproducibility and clinical significance. ERS International Congress 2016 abstracts, Vol. 48(Suppl 60). London, UK, 3 September 2016 - 7 September 2016. View this article in WRRO
• Saunders L, Collier G, Smith L, Marshall H, Biancardi A, Jakymelen D, Strickland S, Gustafsson L, Munro R, Rodgers O , Stewart N et al () 129Xe lung ventilation imaging in patients with long COVID without prior respiratory disease. ISMRM Annual Meeting, 4 May 2024 - 9 May 2024.
• Pilgrim-Morris J, Smith L, Astley J, Saunders L, Collier G, Biancardi A, Tahir B, Marshall H, Hardaker L, Fihn-Wikander T , Hughes R et al () Modelling Whole-Lung and Regional Carbon Monoxide Transfer Factor with Hyperpolarized 129Xe MRI in Asthma and COPD Patients. ISMRM Annual Meeting, 3 July 2023 - 8 July 2023.

Preprints

• Stewart I, Jacob J, George PM, Molyneaux PL, Porter JC, Allen RJ, Baillie JK, Barratt SL, Beirne P, Bianchi SM , Blaikley JF et al () Interstitial lung damage following COVID-19 hospitalisation: an interim analysis of the UKILD Post-COVID study, Cold Spring Harbor Laboratory.
• Saunders LC, Collier GJ, Chan H-F, Hughes PJC, Smith LJ, Watson J, Meiring J, Gabriel Z, Newman T, Plowright M , Eaden JA et al () Longitudinal lung function assessment of patients hospitalised with COVID-19 using ¹H and ¹²⁹Xe lung MRI, Cold Spring Harbor Laboratory.