Dr Ruth Payne
MBChB, MSc, PhD, DTMH, MRCP
Department of Infection, Immunity and Cardiovascular Disease
NIHR Clinical Lecturer
+44 114 215 9522
Full contact details
Department of Infection, Immunity and Cardiovascular Disease
Office: LU108
The Medical School
Beech Hill Road
Sheffield
S10 2RX
- Profile
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I joined the University of Sheffield in 2018 as an NIHR Academic Clinical Lecturer and Honorary SpR in Infectious Diseases and Microbiology.
I graduated from the University of Sheffield Medical School in 2005 and I have worked in Sheffield, New Zealand, Oxford and Nottingham since then.
- Research interests
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My research interests are in vaccinology and malaria infection. I am particularly interested in looking at the innate responses to vaccination and how these are affected by changes in vaccine regimen or adjuvant.
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- Production, quality control, stability, and potency of cGMP-produced Plasmodium falciparum RH5.1 protein vaccine expressed in Drosophila S2 cells. npj Vaccines, 3(1). View this article in WRRO
- Heterologous Two-Dose Vaccination with Simian Adenovirus and Poxvirus Vectors Elicits Long-Lasting Cellular Immunity to Influenza Virus A in Healthy Adults. EBioMedicine, 29, 146-154. View this article in WRRO
- Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions. JCI insight, 2(21). View this article in WRRO
- Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies. JCI insight, 2(12). View this article in WRRO
- Plasmodium vivax Controlled Human Malaria Infection – Progress and Prospects. Trends in parasitology, 33(2), 141-150. View this article in WRRO
- Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01B With Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing ME-TRAP. The Journal of infectious diseases, 214(5), 772-781. View this article in WRRO
- Demonstration of the Blood-Stage Plasmodium falciparum Controlled Human Malaria Infection Model to Assess Efficacy of the P. falciparum Apical Membrane Antigen 1 Vaccine, FMP2.1/AS01. The Journal of infectious diseases, 213(11), 1743-1751. View this article in WRRO
- A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA. The New England journal of medicine, 374, 1635-1646.
All publications
Journal articles
- Promoting ethical payment in human infection challenge studies. The American Journal of Bioethics. View this article in WRRO
- Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK. The Lancet, 397(10269), 99-111. View this article in WRRO
- Harmonization study between three laboratories for expression of malaria vaccine clinical trial IgG antibody ELISA data in µg/mL. Malaria Journal, 18(1). View this article in WRRO
- Human antibodies that slow erythrocyte invasion potentiate malaria-neutralizing antibodies. Cell, 178(1), 216-228. View this article in WRRO
- Structural basis for inhibition of Plasmodium vivax invasion by a broadly neutralizing vaccine-induced human antibody. Nature Microbiology. View this article in WRRO
- Production, quality control, stability, and potency of cGMP-produced Plasmodium falciparum RH5.1 protein vaccine expressed in Drosophila S2 cells. npj Vaccines, 3(1). View this article in WRRO
- Safety and efficacy of novel malaria vaccine regimens of RTS,S/AS01B alone, or with concomitant ChAd63-MVA-vectored vaccines expressing ME-TRAP. npj Vaccines, 3(1). View this article in WRRO
- Heterologous Two-Dose Vaccination with Simian Adenovirus and Poxvirus Vectors Elicits Long-Lasting Cellular Immunity to Influenza Virus A in Healthy Adults. EBioMedicine, 29, 146-154. View this article in WRRO
- Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions. JCI insight, 2(21). View this article in WRRO
- Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies. JCI insight, 2(12). View this article in WRRO
- Plasmodium vivax Controlled Human Malaria Infection – Progress and Prospects. Trends in parasitology, 33(2), 141-150. View this article in WRRO
- Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01B With Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing ME-TRAP. The Journal of infectious diseases, 214(5), 772-781. View this article in WRRO
- Demonstration of the Blood-Stage Plasmodium falciparum Controlled Human Malaria Infection Model to Assess Efficacy of the P. falciparum Apical Membrane Antigen 1 Vaccine, FMP2.1/AS01. The Journal of infectious diseases, 213(11), 1743-1751. View this article in WRRO
- A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA. The New England journal of medicine, 374, 1635-1646.
- ‘It's just a virus’ – viral illness in older people: prevention and management. Reviews in Clinical Gerontology, 23(2), 131-141.
- Systematic telephone triage of possible ‘Swine’ influenza leads to potentially serious misdiagnosis of infectious diseases. Journal of Infection, 59(5), 371-372.
- Commentary on 'Payment in challenge studies: ethics, attitudes and a new payment for risk model'. Journal of Medical Ethics.
- Production, quality control, stability, and potency of cGMP-produced Plasmodium falciparum RH5.1 protein vaccine expressed in Drosophila S2 cells. npj Vaccines, 3(1). View this article in WRRO
- Teaching interests
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I teach on the Diploma of Tropical Medicine and Hygiene (DTM&H) in Sheffield. I am also involved in peer teaching and medical student teaching, particularly during the clinical stages of my post.
In addition, I teach on both the MSc Molecular Medicine and the MSc Antimicrobial Resistance courses.