Electronic Lab Notebooks

What are Electronic Laboratory Notebooks?

Electronic Laboratory Notebooks (ELNs) or Electronic Research Notebooks (ERNs) are software tools developed to replace traditional paper-based lab notebooks and to transition to digital record-keeping. Some of their basic functions include enabling electronic documentation of protocols, observations and experimental data. However, many now encompass a wider array of features such as experiment tracking, version control, data analysis, visualisation tools, inventory oversight and collaborative capabilities. 

What are the benefits of using ELNs?

Electronic Lab Notebooks are integrated into digital research environments thanks to their ability to import and export data and their compatibility with other software tools. This makes them a valuable part of a researcher’s Research Data Management (RDM) toolkit and improves data security, organisation and efficiency. ELNs make it easier for researchers to collaborate, whether within their own team or with external partners, by providing a shared digital workspace. Additionally, ELNs support Good Research & Innovation Practice (GRIP) by enabling clear documentation, tracking, and tracing of research activities and results over time. As digital tools, they also help prevent data loss and reduce errors. ELNs also promote the FAIR data principles by supporting features such as metadata assignment, tagging, and the use of persistent identifiers. Some high-end ELNs have two-way integration with other data sources, tools, publishers, and repositories.

How to choose the right ELN?

You should begin with a clear understanding of your lab’s specific needs and workflows. Start by identifying the essential functionalities you require, such as templates, task assignments, user rights, inventory management, data security, budget, and potential for collaborative development or expansion. Consider discipline-specific ELNs that offer tailored features for your field.

Since different ELNs offer varying features, it’s important to investigate several options to determine the best fit for your research project. Speak with colleagues who already use ELNs as they can offer valuable insights and may even demonstrate how they use their platforms. Additionally, consider using the ELN Finder to help identify suitable options, and use an ELN Comparison Matrix to discover and evaluate features that may be relevant to your work.

If you're considering using a tool or platform that isn't provided by the University of Sheffield, you must follow guidance from the University Information Security team to ensure compliance with university policies and UK regulations.

Also, be mindful of any restrictions on the type of data you plan to store in your ELN. Sensitive data or information governed by funders or partners may have specific requirements you need to follow.

To request approval for a new digital solution, follow the process outlined here.

When you're ready to submit your request, use this form in TopDesk.

ELNs vs. LIMS

Electronic Laboratory Notebooks and Laboratory Information Management Systems (LIMS) are both digital tools used in laboratory environments, but they serve distinct purposes. ELNs are primarily designed for documenting scientific research, capturing experimental protocols, observations, and results in a flexible, user-friendly format that replaces traditional paper notebooks. In contrast, LIMS are structured systems focused on managing laboratory workflows, including sample tracking, data standardisation, regulatory compliance, and operational efficiency. While ELNs support creative and exploratory research processes, LIMS are used for routine testing, data integrity, and traceability. ELNs and LIMS can complement each other, with ELNs supporting the research side and LIMS handling process-driven lab operations.

Who to contact for support?

Speak to Research IT for further guidance and support.

ELNs in Practice - Recording from Open Research Conversation

In this presentation, Endre Kiss-Toth and Alice Seleiro share practical insights into implementing ELNs in a lab setting, with examples, tips, and lessons learned.

Help us understand how Electronic Lab Notebooks (ELNs) are used at the University of Sheffield

We are currently gathering information on how Electronic Lab Notebooks (ELNs) are being used across the University of Sheffield. If you use an ELN in your work or research, we would greatly appreciate it if you could take a few minutes to complete this short survey.