Dr Sophie Whyte

MMath (Warwick), PhD (Birmingham)

School of Health and Related Research

Senior Research Fellow

sophie.whyte@sheffield.ac.uk
+44 114 222 0859

Full contact details

Dr Sophie Whyte
School of Health and Related Research
1025
Regent Court (ScHARR)
30 Regent Street
Sheffield
S1 4DA
Profile

I joined the HEDS section of ScHARR as a mathematical modeller in September 2007. Previous to this, I obtained a Masters in Mathematics from the University of Warwick and a PhD in Pure Mathematics (Group Theory) from Birmingham University.

Research interests

My broad research is focused on mathematical modelling within health economics. I have gained significant expertise and experience in two related areas:

  • Bayesian calibration of cancer natural history models: This is my main methodological research theme, please see MDM publication http://mdm.sagepub.com/content/31/4/625 and Example Excel model using the Metropolis Hastings algorithm to calibrate a state transition model available to down load from the Downloads box)
  • Early diagnosis of bowel cancer: I have substantial experience in early diagnosis of cancer generally having worked on more than 15 projects in this area of applied research. My main expertise lies in the modelling bowel cancer screening to inform national bowel cancer screening policy.

In addition to these main research themes I have undertaken research to inform policy making: Health Technology Assessment (HTA) for NICE, and research as part of the Policy Research Unit in Economic Evaluation of Health and Care Interventions (EEPRU) for DH (http://www.eepru.org.uk/)

Publications

Show: Featured publications All publications

Journal articles

Reports

  • Whyte S, Chilcott J, Essat M, Stevens J, Wong R & Kalita N (2011) Reappraisal of the options for colorectal cancer screening View this article in WRRO RIS download Bibtex download

All publications

Journal articles

Conference proceedings papers

  • Ren S, Minton J, Whyte S, Latimer N & Stevenson M (2017) PRM152 - How to sample ordered parameters in probabilistic sensitivity analysis. Value in Health, Vol. 20(9) (pp A758-A758) RIS download Bibtex download
  • Kearns B, Chilcott & whyte (2016) Flexible parametric survival models and time-series analysis for extrapolating time-varying treatment effects in health technology assessment. Flexible parametric survival models and time-series analysis for extrapolating time-varying treatment effects in health technology assessment, 5 September 2016 - 8 September 2016. RIS download Bibtex download
  • Faria R, Walker S, Whyte S, Dixon S, Sculpher M & Palmer S (2015) The value of implementation: how to invest in getting cost-effective technologies into practice. Framework and application to novel oral anticoagulants in the prevention of stroke and systemic embolism. HESG. Leeds RIS download Bibtex download
  • Faria R, Whyte S, Palmer S & Hoomans T (2014) WORKSHOP 2999: From evaluation to implementation: how to ensure efficient investment in implementation of cost-effective technologies in clinical practice?. ISPOR. Amsterdam, 9 November 2014 - 12 November 2014. RIS download Bibtex download
  • Rowen D, Brazier J, Mukuria C, Whyte S, Keetharuth A, Risa Hole A, Tsuchiya A & Shackley P (2014) Rowen D, Brazier J, Mukuria C, Whyte S, Keetharuth A, Risa Hole A, Tsuchiya A, Shackley P. Eliciting societal preferences for burden of illness, therapeutic improvement and end of life for value based pricing.. HESG. Sheffield, UK, 8 January 2014. RIS download Bibtex download
  • Asaria M, Griffin S, Cookson R, Whyte S & Tappenden P (2013) A framework for the cost-equality analysis of health care programmes. ISPOR. Dublin RIS download Bibtex download
  • Bessey A, Whyte S, Minton J & Chilcott J (2013) Economic evaluation of an electrical impedance spectroscopy (EIS) device used as an adjunct to colposcopy. VALUE IN HEALTH, Vol. 16(7) (pp A407-A407) RIS download Bibtex download
  • Whyte S (2013) Cost effectiveness analysis of an early awareness campaign for colorectal cancer. Cancer Outcomes Conference. Brighton RIS download Bibtex download
  • Whyte S (2013) Effectiveness and cost effectiveness of an awareness campaign for colorectal cancer: A mathematical modelling study. Cancer Research UK NAEDI conference. Cambridge, UK RIS download Bibtex download
  • Whyte S (2012) The cost effectiveness of an early awareness campaign for colorectal cancer. SMDM. Oslo, Norway, 10 June 2012 - 12 June 2012. RIS download Bibtex download
  • Whyte S, Scope A & Tappenden P (2012) The cost effectiveness of an early awareness campaign for colorectal cancer. SMDM. Oslo, Norway RIS download Bibtex download
  • Whyte S & Chilcott J (2010) Using a natural history model in combination with screening data to estimate the test characteristics of the FOB test in the English bowel cancer screening programme. Methods for evaluating medical tests and biomarkers. Birmingham, UK RIS download Bibtex download
  • Whyte S (2009) Bayesian calibration of a natural history model for colorectal cancer. ISPOR. Paris RIS download Bibtex download
  • Whyte S, Dixon S, Faria R, Walker S, Sculpher M & Palmer S () The value of investing implementation activities: A case study in natriuretic peptide testing for diagnosing suspected heart failure (2014) RIS download Bibtex download

Reports

  • Srivastava T, Chambers D, Thomas C & Whyte S (2019) ECASS health economic feasibility study View this article in WRRO RIS download Bibtex download
  • Whyte S, Thomas C, Kearns B, Webster M & Chilcott J (2017) Optimising Bowel Cancer Screening Phase 1: Optimising the cost effectiveness of repeated FIT screening and screening strategies combining bowel scope and FIT screening View this article in WRRO RIS download Bibtex download
  • Pollard D, Cree I & Whyte S (2016) Generic Cancer Screen - Economic modelling report View this article in WRRO RIS download Bibtex download
  • Whyte S, Chambers D & Wong R (2015) Degarelix for treating advanced hormone-dependent Prostate cancer [ID590] Spinal cord compression associated with hormonal therapy in men with hormone-dependent metastatic prostate cancer: a systematic review and economic assessment RIS download Bibtex download
  • Faria R, Walker S, Whyte S, Dixon S, Palmer S & Sculpher M (2014) Getting cost-effective technologies into practice: the value of implementation An application to novel anticoagulants in the prevention of stroke and systemic embolism RIS download Bibtex download
  • Walker S, Faria R, Whyte S, Dixon S, Palmer S & Sculpher M (2014) Getting cost-effective technologies into practice: the value of implementation. Report on framework for valuing implementation initiatives RIS download Bibtex download
  • Whyte S, Dixon S, Faria R, Walker S, Palmer S & Sculpher M (2014) Getting cost-effective technologies into practice: the value of implementation. An application to B-type natriuretic peptide (BNP) testing in diagnosing chronic heart failure View this article in WRRO RIS download Bibtex download
  • Rowen D, Brazier J, Mukuria C, Keetharuth A, Rise Hole A, Tsuchiya A, Whyte S & Shackley P (2014) Update: Eliciting societal preferences for weighting QALY's according to burden of illness, size of gain and end of life View this article in WRRO RIS download Bibtex download
  • Whyte S, Brazier J, Rowen D, Mukuria C, Keetharuth A, RiseHole A, Tsuchiya A & Shackley P (2013) Eliciting societal preferences for burden of illness, therapeutic improvement and end of life for value based pricing: a report of the main survey View this article in WRRO RIS download Bibtex download
  • Whyte S, Harnan S, Scope A, Simpson E, Tappenden P, Duffy S, Rachet B, Sculpher M, Hinde S, McKenna C & Wong R (2012) Early awareness interventions for cancer: Colorectal cancer View this article in WRRO RIS download Bibtex download
  • Hinde S, McKenna C, Whyte S, Peake M, Callister M, Rogers T & Sculpher M (2012) Modelling the cost-effectiveness of early awareness interventions for the early detection of lung cancer RIS download Bibtex download
  • Whyte S, Cooper KL, Stevenson MD, Madan J & Akehurst R (2011) Cost-effectiveness of granulocyte colony-stimulating factor prophylaxis for febrile neutropenia in breast cancer in the United Kingdom RIS download Bibtex download
  • Whyte S, Cooper KL, Stevenson MD & Akehurst R (2011) Cost-effectiveness of granulocyte colony-stimulating factor prophylaxis for febrile neutropenia in patients with non-Hodgkin's lymphoma in the United Kingdom (UK) RIS download Bibtex download
  • Whyte S, Chilcott J, Essat M, Stevens J, Wong R & Kalita N (2011) Reappraisal of the options for colorectal cancer screening View this article in WRRO RIS download Bibtex download
  • Madan J, Cooper KL, Stevenson MD, Whyte S & Akehurst R (2009) Consistency between direct trial evidence and Bayesian Mixed Treatment Comparison: Is head-to-head evidence always more reliable? RIS download Bibtex download
  • Cooper KL, Madan J, Whyte S, Stevenson MD & Akehurst R (2009) Granulocyte colony-stimulating factors for prevention of febrile neutropenia following chemotherapy: systematic review and meta-analysis RIS download Bibtex download
  • Sharp L, Whyte S, Ceillachair A, Comber H, Tilson L, Usher C, Walsh C, Barry M, Tappenden P, Chilcott J & Staines A (2009) Options for a population-based colorectal cancer screening programme in Ireland: a health technology assessment RIS download Bibtex download
  • Whyte S, Chilcott J & Headley J (2008) Health economics of Colonix: A new diagnostic test in colorectal cancer RIS download Bibtex download

Posters

  • Whyte S, Dixon S, Faria R, Walker S, Sculpher M & Palmer S The value of investing in implementation activities: A case study in natriuretic peptide testing for diagnosing suspected heart failure (SMDM 15th Biennial European Meeting 8-10 June 2015). RIS download Bibtex download
Research group

If you are interested in pursuing a PhD which may fit with my research areas described above please contact me regarding PhD supervision.

Teaching interests

I am module lead for the Dissertation on the MSc in Health Economics and Decision Modelling.