Dr
Sarah
Ren
PhD
School of Medicine and Population Health
Research Fellow in Statistics
+44 114 222 0873
Full contact details
Regent Court (ScHARR)
- Profile
-
I joined SCHARR in 2022 as a Research Associate in Statistics and am a member of SCHARR-TAG, an external assessment group supporting NICE technology appraisals. My work involves critically appraising the statistical methods used in NICE health technology assessment (HTA) submissions, as well as developing and conducting meta-analyses.
My research interests are centred around statistical methods for evidence synthesis and HTA. These include population-adjusted indirect comparisons, meta-analysis, diagnostic methods, survival analysis, Bayesian statistics, and social network analysis.
Before joining SCHARR, I spent six years researching social networks and graphical models as a statistician. This work provided me with a broad statistical foundation and experience across a wide range of methods, including Bayesian statistics, nonparametric methods, and optimisation.
I hold an NIHR Development and Skills Enhancement (DSE) award, which supports my work on developing statistical methods to strengthen evidence synthesis and decision-making in HTA.
- Qualifications
-
PhD in Statistics (University of Kent)
- Research interests
-
• Population-adjusted indirect comparisons
• Meta-analysis
• Comparative effectiveness research
• Survival analysis
• Bayesian hierarchical modelling
• Social network analysis and graphical models
- Publications
-
Show: Featured publications All publications
Featured publications
This person does not have any publications available.
All publications
Journal articles
- PillCam COLON 2 for investigation of the colon through direct visualisation: systematic review and economic evaluation. Health Technology Assessment, 30(58), 1-164. View this article in WRRO
- Evaluating amyloid-beta as a surrogate endpoint in trials of anti-amyloid-beta drugs in Alzheimer’s disease: a Bayesian meta-analysis. Journal of Comparative Effectiveness Research, 15(1). View this article in WRRO
- EE383 Economic evaluation of second-generation colon capsule endoscopy for investigation of the colon through direct visualization. Value in Health, 28(12, Supplement 1), S180-S181. View this article in WRRO
- CO180 Pillcam COLON 2 for investigation of the COLON through direct visualization: a systematic review. Value in Health, 28(12, Suppl 1), S78-S78. View this article in WRRO
- Diagnostic strategies for suspected acute aortic syndrome: systematic review, meta-analysis, decision-analytic modelling and value of information analysis. Health Technology Assessment, 29(45), 1-36. View this article in WRRO
- Quantitative bias analysis for unmeasured confounding in unanchored population-adjusted indirect comparisons. Research Synthesis Methods, 16(3), 509-527. View this article in WRRO
- SA48 Evaluating Amyloid-Beta as a Surrogate Endpoint for Cognitive Function in Alzheimer’s Disease: A Bayesian Hierarchical Meta-Analysis of Randomized Controlled Trials of Anti-Amyloid Monoclonal Antibodies. Value in Health, 27(12), S623-S623.
- Diagnostic accuracy of the aortic dissection detection risk score alone or with D-dimer for acute aortic syndromes: systematic review and meta-analysis. PLOS ONE, 19(6). View this article in WRRO
- Diagnostic accuracy of D-dimer for acute aortic syndromes: systematic review and meta-analysis. Annals of Emergency Medicine, 84(4), 409-421. View this article in WRRO
- Advancing unanchored simulated treatment comparisons: a novel implementation and simulation study. Research Synthesis Methods, 15(4), 657-670. View this article in WRRO
- MSR159 A Novel Unanchored Simulated Treatment Comparison Approach for Time-to-Event Data. Value in Health, 26(12), S424-S424.
- Bayesian nonparametric mixtures of Exponential Random Graph Models for ensembles of networks. Social Networks, 74, 156-165. View this article in WRRO
- Review of handbook of graphs and networks in people analytics: with examples in R and Python by Keith McNulty. Journal of Agricultural, Biological and Environmental Statistics. View this article in WRRO
Conference proceedings
- SA90 Systematic review of doubly robust methods for population-adjusted indirect comparisons. Value in Health, Vol. 28(12, Suppl 1) (pp S663-S664). Glasgow, Scotland, 9 November 2025 - 9 November 2025. View this article in WRRO
- MSR214 Using directed acyclic graphs in matching-adjusted indirect comparison and simulated treatment comparison: systematic review and methodological insights. Value in Health, Vol. 28(12, Suppl 1) (pp S537-S538). Glasgow, Scotland, UK, 9 November 2025 - 9 November 2025. View this article in WRRO
- PILLCAM COLON 2 FOR INVESTIGATION OF THE COLON THROUGH DIRECT VISUALIZATION: A SYSTEMATIC REVIEW. VALUE IN HEALTH, Vol. 28(12)
- EVALUATING AMYLOID-BETA AS A SURROGATE ENDPOINT FOR COGNITIVE FUNCTION IN ALZHEIMER'S DISEASE: A BAYESIAN HIERARCHICAL META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS OF ANTI-AMYLOID MONOCLONAL ANTIBODIES. VALUE IN HEALTH, Vol. 27(12) (pp S623-S623)
- 2613 Diagnostic accuracy of the aortic dissection detection risk score alone or with D-dimer for acute aortic syndromes: systematic review and meta-analysis. RCEM Annual Scientific Conference 2024 Abstracts (pp A9.1-A9)
- A NOVEL UNANCHORED SIMULATED TREATMENT COMPARISON APPROACH FOR TIME-TO-EVENT DATA. VALUE IN HEALTH, Vol. 26(12) (pp S424-S424)
Preprints
- PillCam COLON 2 for investigation of the colon through direct visualisation: systematic review and economic evaluation. Health Technology Assessment, 30(58), 1-164. View this article in WRRO
- Research group
-
• SCHARR Technology Assessment group (TAG)
• Sheffield Evidence Network for Screening Synthesis (SENSS)
- Grants
-
• NIHR Development and Skills Enhancement (DSE) award, 2026-2028, Principal investigator
• Sheffield Evidence Network for Screening Synthesis (SENSS), 2025-2030, Co-investigator
• Lilly Research Award Program (LRAP), 2024-2026
• NIHR Technology Assessment Reviews (TARs), 2022-2027
- Teaching interests
-
• Evidence synthesis
• Survival analysis
- Professional activities and memberships
-
International Society for Clinical Biostatistics (ISCB)