Dr Paul Morris MBChB MRCP BMedSci

NIHR Clinical Lecturer in Cardiology Paul Morris

Department of Infection, Immunity & Cardiovascular Disease
University of Sheffield
Medical School
Beech Hill Road
Sheffield
S10 2RX

Tel: +44 (0) 114 215 9548
Fax: +44 (0) 114 271 1863
Email: paul.morris@sheffield.ac.uk

Biography:

I joined the University of Sheffield in 1998 when I came to study Medicine. During this time, I developed an interest in cardiology and research. I intercalated a BMedSci degree and investigated the role of testosterone in men with heart disease. I qualified as a medical doctor in 2004 and became a member of the Royal College of Physicians in 2007. I am currently a British Heart Foundation Research Training Fellow within the Department of Cardiovascular Science. I am also a member of the Insigneo Institute for in silico Medicine and am an Honorary Specialist Training Registrar in Cardiology at Sheffield Teaching Hospitals NHS Foundation Trust.

Research Interests:

My research interests are in computational modelling of cardiac physiology and heart disease. I am interested in the construction, development and validation of computational workflows which predict cardiac physiology. My current work is focused on the development of a model of intra-coronary physiology. Our VIRTUheart™ model computes virtual fractional flow reserve (vFFR) a marker of coronary artery disease significance and a guide to treatment.

Teaching Interests:

I enjoy lecturing clinical cardiology to undergraduates and post-graduates. I also teach clinical skills to medical students and doctors on the wards and in the clinic. A textbook of the cardiovascular system and clinical cardiology is currently in preparation.

Professional Activities:

Other professional activities and interests include public engagement with science and the development of assessments for clinical knowledge and skills.

Current Projects:

  • Virtual coronary physiology: an angiogram is all you need. Wellcome Trust and Department of Health. Health Innovation Challenge Fund (£671,856).
  • Modelling the significance of coronary artery disease (British Heart Foundation Personal Fellowship; £166,125)
  • NIHR Cardiovascular Biomedical Research Unit Entry level Fellowship 2011 (£60 000)

VIRTUheart Images


Images from the VIRTUheartTM workflow. VIRTUheartTM predicts pressure changes within coronary arteries. A and B are angiogram images from a patient with coronary heart disease. The arrows point to an area of disease (narrowing). Image C shows the reconstructed or virtual artery. The colours indicate the computed blood pressure within the artery. A drop in pressure can be seen beyond the diseased segment. D and E show the artery after percutaneous coronary intervention (stent insertion). F shows the virtual artery, this time with no significant pressure changes. Doctors can use these computed pressure measurements to help guide treatment decisions.

Publications:

For key publications see below. For a full list of publications click here.

Journal articles

Conference proceedings papers