Dr Paul Morris BMedSci MBChB MRCP PhD PGCME FHEA
NIHR Clinical Lecturer in Cardiology
Mathematical Modelling in Medicine Group
Department of Infection, Immunity & Cardiovascular Disease
University of Sheffield
Beech Hill Road
Tel: +44 (0) 114 215 9548
Fax: +44 (0) 114 271 1863
I joined the University of Sheffield in 1998 when I came to study Medicine. During this time, I developed an interest in cardiology and research. I intercalated a BMedSci degree and investigated the role of testosterone in men with heart disease. I qualified as a medical doctor in 2004 and became a member of the Royal College of Physicians in 2007. I am currently a NIHR Clinical Lecturer in the Mathematical Modelling in Medicine Group, part of the Department of Infection, Immunity and Cardiovascular Disease. I am also Director for Clinical Translation at the Insigneo Institute for in silico Medicine. I am an Honorary Specialist Training Registrar in Cardiology at Sheffield Teaching Hospitals NHS Foundation Trust. As an interventional cardiologist, my areas of clinical interest include percutaneous coronary intervention (PCI), coronary physiological assessment and cardiac CT.
My research interests are in computational modelling of cardiac physiology and heart disease. I am interested in the construction, development and validation of computational workflows which predict cardiac physiology. My current work is focused on the development of models of intra-coronary physiology including pressure and flow. Our VIRTUheart™ model computes intracoronary physiology and virtual fractional flow reserve (vFFR) a marker of coronary artery disease significance and a guide to treatment.
I enjoy lecturing clinical cardiology to undergraduates and post-graduates. I teach clinical skills to medical students and doctors on the wards and in the clinic. A textbook of the cardiovascular system and clinical cardiology is currently in preparation. I also enjoy teaching about cardiac physiology and fluid dynamics modelling. I have a Postgraduate Certificate in Medical Education and have recently become a Fellow of the Higher Education Academy.
Other professional activities and interests include public engagement with science and the development of assessments for clinical knowledge and skills.
- National Institute for Health Research, Invention for Innovation (i4i). Gunn JP, Morris PD, Hose DR, Lawford PV. ‘A prototype tool to calculate 'virtual' myocardial fractional flow reserve (vFFR) non-invasively (VIRTU-3)’. R/146986-11-1. £294,746. March 2017 – March 2019.
- National Institute for Health Research Clinical Lectureship. Morris PD.
For key publications see below. For a full list of publications click here.
- Morris PD & Gunn JP (2017) Computing Fractional Flow Reserve From Invasive Coronary Angiography. Circulation: Cardiovascular Interventions, 10(9), e005806-e005806.
- Morris PD, Silva Soto DA, Feher JFA, Rafiroiu D, Lungu A, Varma S, Lawford PV, Hose DR & Gunn JP (2017) Fast Virtual Fractional Flow Reserve Based Upon Steady-State Computational Fluid Dynamics Analysis: Results From the VIRTU-Fast Study. Journal of American College Cardiology Basic to Translational Science, 2(4), 434-446. View this article in WRRO
- Garg P, Morris P, Fazlanie AL, Vijayan S, Dancso B, Dastidar AG, Plein S, Mueller C & Haaf P (2017) Cardiac biomarkers of acute coronary syndrome: from history to high-sensitivity cardiac troponin. Internal and Emergency Medicine, 12(2), 147-155. View this article in WRRO
- Gosai JN, Charalampidis P, Nikolaidou T, Parviz Y, Morris PD, Channer KS, Jones TH & Grech ED (2016) Revascularization with percutaneous coronary intervention does not affect androgen status in males with chronic stable angina pectoris. Andrology, 4(3), 486-491.
- Morris PD, Taylor J, Boutong S, Brett S, Louis A, Heppenstall J, Morton AC & Gunn JP (2016) When is rotational angiography superior to conventional single-plane angiography for planning coronary angioplasty?. Catheterization and Cardiovascular Interventions, 87(4), E104-E112. View this article in WRRO
- Morris PD, Narracott A, Von Tengg-Kobligk H, Soto DAS, Hsiao S, Lungu A, Evans P, Bressloff NW, Lawford PV, Rodney Hose D & Gunn JP (2016) Computational fluid dynamics modelling in cardiovascular medicine. Heart, 102(1), 18-28. View this article in WRRO
- Morris PD, Van De Vosse FN, Lawford PV, Hose DR & Gunn JP (2015) "virtual" (Computed) Fractional Flow Reserve Current Challenges and Limitations. JACC: Cardiovascular Interventions, 8(8), 1009-1017.
- Saraf K, Morris P, Garg P, Sheridan P & Storey R (2014) Non-vitamin K antagonist oral anticoagulants (NOACs): clinical evidence and therapeutic considerations. Postgraduate Medical Journal, 90(1067), 520-528.
- Morris PD, Ryan D, Morton AC, Lycett R, Lawford PV, Hose DR & Gunn JP (2013) Virtual fractional flow reserve from coronary angiography: modeling the significance of coronary lesions: results from the VIRTU-1 (VIRTUal Fractional Flow Reserve From Coronary Angiography) study.. JACC Cardiovasc Interv, 6(2), 149-157.
- Morris PD, Robinson T & Channer KS (2012) Reversible heart failure: toxins, tachycardiomyopathy and mitochondrial abnormalities.. Postgrad Med J, 88(1046), 706-712.
- Morris PD & Channer KS (2012) Testosterone and cardiovascular disease in men. Asian Journal of Andrology, 14(3), 428-435.
- Green LR, Monk PN, Partridge LJ, Morris P, Gorringe AR & Read RC (2011) Cooperative role for tetraspanins in adhesin-mediated attachment of bacterial species to human epithelial cells.. Infect Immun, 79(6), 2241-2249. View this article in WRRO
- Malkin CJ, Pugh PJ, Morris PD, Asif S, Jones TH & Channer KS (2010) Low serum testosterone and increased mortality in men with coronary heart disease. Heart, 96(22), 1821-1825.
- Smith AM, Morris P, Rowell KO, Clarke S, Jones TH & Channer KS (2006) Junior doctors and the full shift rota--psychological and hormonal changes: a comparative cross-sectional study.. Clin Med (Lond), 6(2), 174-177.
- Malkin CJ, Pugh PJ, Morris PD, Kerry KE, Jones RD, Jones TH & Channer KS (2004) Testosterone replacement in hypogonadal men with angina improves ischaemic threshold and quality of life. Heart, 90(8), 871-876.
- Morris PD, Malkin CJ, Channer KS & Jones TH (2004) A mathematical comparison of techniques to predict biologically available testosterone in a cohort of 1072 men. European Journal of Endocrinology, 151(2), 241-249.