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BMS6007: Mass spectrometry-based proteomics and metabolomics course

17-21 January 2022

Course summary

Mass spectrometry-based proteomics and metabolomics are powerful approaches to investigate biological problems in an unbiased and quantitative manner. In recent years, rapid technological developments have allowed unprecedented insights into protein function and has made proteomics an essential tool for many areas of biological and medical research. The field of proteomics spans a wide range of molecular complexity from protein synthesis and degradation, protein interactions and protein complexes to a variety of post-translational modifications. Metabolomics, the systematic study of the diverse range of small molecule products of the proteome, is driven by a number of mass spectrometry approaches and has many applications from plants to the clinic.

This course aims to provide an introduction to mass spectrometry, proteomics and metabolomics and will explore how these technologies can be used to quantitatively dissect protein-protein interactions, characterise post-translational modifications and profile metabolomes and proteomes.

Topics will include the following

  • Introduction to Mass Spectrometry
  • Quantitative proteomics
  • Protein-protein interactions
  • Post-translational modifications
  • Targeted & Non-targeted Metabolomics
  • Imaging Mass Spectrometry
  • Virtual tour of the Faculty of Science Spectrometry Centre facilities

Course programme

Day 1: Monday 17th January 2022 (10.00am - 12.00pm)

Time

Session

Instructor

10.00am

Lecture 1: Introduction I: Mass Spectrometry

Mark Collins

11.00am

Short break

11.05am

Lecture 2: Introduction 2: Chromatography

Heather Walker

Day 2: Tuesday 18th January 2022 (10.00am - 12.00pm)

Time

Session

Instructor

10.00am

Lecture 3: Introduction to Proteomics and Proteome bioinformatics

Mark Collins

11.00am

Short break

11.05am

Lecture 4: Targeted quantification

Khoa Pham

Day 3: Wednesday 19th January 2022 (10.00am - 12.00pm)

Time

Session

Instructor

10.00am

Lecture 5: Global quantitative proteomics

Mark Collins

11.00am

Short break

11.05am

Lecture 6: Post-translational modifications

Khoa Pham

Day 4: Thursday 20th January 2022 (10.00am - 12.00pm)

Time

Session

Instructor

10.00am

Lecture 7: Protein interactions

Mark Collins

11.00am

Short break

11.05am

Lecture 8: Introduction to Metabolomics

Heather Walker

Day 5: Friday 21st January 2022 (10.00am - 12.15pm)

Time

Session

Instructor

10.00am

Lecture 9: MALDI imaging

Heather Walker

11.00am

Interactive session: The importance of experimental design

Various instructors

12.00pm

Virtual tour of the Faculty of Science Spectrometry Centre

Questions?

Contact us if you have any questions about this course or any additional interest in learning about mass spectrometry.

How to register

If you want to register, please fill in the registration form through this link.

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