Dr Anthony J Bullock

BSc, PhD

Department of Materials Science and Engineering

Research Associate

Profile

I joined the Tissue Engineering group in 2000 as a senior postdoctoral research associate, involved in interdisciplinary work in the development of tissue engineering of skin and wound healing.

I obtained my degree in Biomedical Technology at Sheffield City Polytechnic in 1992, including a year-long industrial placement at Porton Down, learning cell culture and rudimentary experiments on in vitro skin models. I then researched the role of protein kinase C in calcium signalling during agonist-induced platelet activation, and development of partial agonists to the IP3 receptor at the University of Bath.

My PhD in physiology, at the Physiological Laboratory in Liverpool, focussed on species and developmental changes in response to hypoxia in the smooth muscle of the ureter. I then became a research associate at Liverpool University studying the effects of bacterial infection on the human ureter.

Research interests

I’m currently working on an interdisciplinary project funded by Proctor and Gamble to investigate inflammatory cytokines and their effect on tissue-engineered skin models. Data on the effects on the morphology of the developing epidermis is being used to develop an agent-based computer model of human epidermis.

This interdisciplinary research incorporates the following areas:-

  • Tissue engineering of skin
  • Inflammation and its effects on epidermal morphology
  • Agent-based computer modelling
Publications

Journal articles

Chapters

  • Wray S, Buttel N, Bullock AJ & Duquette RA (1997) pH and Smooth Muscle Function: Regulation and Functional Effects. In Taylor EW, Eggington, S & Raven J (Ed.), Regulation of Tissue pH in Plants and Animals: A Reappraisal of Current Techniques Cambridge, UK: Cambridge University Press. RIS download Bibtex download

Conference proceedings papers

  • MacNeil S, Hillary CJ, Bullock AJ & Chapple CR (2015) Estradiol Releasing Scaffolds for the Treatment of Pelvic Floor Disorders. TISSUE ENGINEERING PART A, Vol. 21 (pp S202-S202) RIS download Bibtex download
  • MacNeil S, Mangera A, Bullock AJ, Patterson J, Osman N & Chapple C (2015) Nine Year Follow Up on Tissue Engineered Buccal Mucosa used for Urethroplasty - What have we Learnt?. TISSUE ENGINEERING PART A, Vol. 21 (pp S34-S34) RIS download Bibtex download
  • Shahbuddin M, Bullock A, Rimmer S & MacNeil S (2015) Physiological and Biological Effects of Konjac Glucomannan Hydrogels on Human Tissue Engineered Skin. TISSUE ENGINEERING PART A, Vol. 21 (pp S304-S304) RIS download Bibtex download
  • MacNeil S, Hillary CJ, Roman S, Bullock AJ & Chapple CJ (2015) Composite Materials for Pelvic Floor Repair Which Cope with Dynamic Distension and Support Cell Integration. TISSUE ENGINEERING PART A, Vol. 21 (pp S215-S215) RIS download Bibtex download
  • Hillary C, Roman S, Bullock A, Chapple C & MacNeil S (2015) RESPONSE OF SCAFFOLD MATERIALS DESIGNED FOR TREATMENT OF STRESS URINARY INCONTINENCE (SUI) AND PELVIC ORGAN PROLAPSE (POP) TO DISTENSION. NEUROUROLOGY AND URODYNAMICS, Vol. 34 (pp S291-S292) RIS download Bibtex download
  • Osman I, Roman S, Bullock AJ, Sefat F, Chapple CR & MacNeil S (2014) Improving elastogenesis in a tissue engineered repair material for pelvic floor surgery. BRITISH JOURNAL OF SURGERY, Vol. 101 (pp 60-60) RIS download Bibtex download
  • Regueros RS, Albersen M, Manodoro S, Zia S, Osman N, Bullock AJ, Chapple C, Deprest J & Sheila M (2013) ACUTE HOST RESPONSE AGAINST A NOVEL TISSUE ENGINEERED REPAIR MATERIAL FOR THE SURGICAL MANAGMENT OF STRESS URINARY INCONTINENCE AND PELVIC ORGAN PROLAPSE. NEUROUROLOGY AND URODYNAMICS, Vol. 32(6) (pp 555-556) RIS download Bibtex download
  • Osman I, Roman S, GIgliobianco G, Bullock AJ, Chapple C & MacNeil S (2013) Biomechanical optimisation of a tissue engineered prosthesis for pelvic floor repair. BRITISH JOURNAL OF SURGERY, Vol. 100 (pp 66-66) RIS download Bibtex download
  • Regueros RS, Mangera A, Osman N, Bullock AJ, Capple CR & MacNeil S (2012) DEVELOPING AN AUTOLOGOUS ENGINEERED CONNECTIVE TISSUE USING A BIODEGRADABLE SCAFFOLD FOR THE TREATMENT OF STRESS URINARY INCONTINENCE AND PELVIC ORGAN PROLAPSE. NEUROUROLOGY AND URODYNAMICS, Vol. 31(6) (pp 917-919) RIS download Bibtex download
  • Mangera A, Roman S, Bullock A, Chapple CR & MacNeil S (2012) Assessment of a variable stress rig to improve the properties of a tissue engineered prosthesis for use in stress urinary incontinence and pelvic organ prolapse. BRITISH JOURNAL OF SURGERY, Vol. 99 (pp 58-59) RIS download Bibtex download
  • Mangera A, Bullock AJ, MacNeil S & Chapple CR (2011) Engineering a novel tissue engineered autologus prosthesis for use in stress urinary incontinence (SUI) and pelvic organ prolapse (POP) repair. BRITISH JOURNAL OF SURGERY, Vol. 98(6) (pp E6-E6) RIS download Bibtex download
  • Mangera A, Bullock AJ, MacNeil S & Chapple CR (2011) Increasing collagen production and contraction with ascorbate in a tissue engineered autologus prosthesis for use in the treatment of stress urinary incontinence (SUI) and pelvic organ prolapse (POP). BRITISH JOURNAL OF SURGERY, Vol. 98(6) (pp E7-E7) RIS download Bibtex download
  • Mangera A, Bullock AJ, MacNeil S & Chapple CR (2011) Creating a tissue engineered prosthesis for stress urinary incontinence and pelvic organ prolapse, which scaffold?. BRITISH JOURNAL OF SURGERY, Vol. 98 (pp 4-5) RIS download Bibtex download
  • Bullock AJ, Mangera A, MacNeil S & Chapple CR (2011) Development of aseptically produced scaffolds for substitution urethroplasty. BRITISH JOURNAL OF SURGERY, Vol. 98 (pp 54-54) RIS download Bibtex download
  • Mangera A, Bullock A, MacNeil S & Chapple CR (2011) COMPARATIVE INVESTIGATION OF SEVEN CANDIDATE SCAFFOLDS FOR THE PRODUCTION OF AN AUTOLOGOUS TISSUE ENGINEERED CONNECTIVE TISSUE FOR USE IN STRESS URINARY INCONTINENCE AND PELVIC ORGAN PROLAPSE. NEUROUROLOGY AND URODYNAMICS, Vol. 30(6) (pp 868-870) RIS download Bibtex download
  • Mangera A, Bullock AJ, Mac Neil S & Chapple CR (2010) A NOVEL TISSUE ENGINEERING APPROACH FOR CREATING PROSTHESES FOR THE TREATMENT OF STRESS URINARY INCONTINENCE (SUI) & PELVIC ORGAN PROLAPSE (POP). EUROPEAN UROLOGY SUPPLEMENTS, Vol. 9(2) (pp 328-328) RIS download Bibtex download
  • Mangera A, Bullock AJ, MacNeil S & Chapple C (2010) DEVELOPING AN AUTOLOGOUS TISSUE ENGINEERED PROSTHESIS FOR USE IN STRESS URINARY INCONTINENCE AND PELVIC ORGAN PROLAPSE. NEUROUROLOGY AND URODYNAMICS, Vol. 29(6) (pp 1129-1130) RIS download Bibtex download
  • Harrison CA, Gossiel F, Bullock AJ, Blumsohn A & Mac Neil S (2005) Investigation of the mechanism of contraction of tissue-engineered skin. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, Vol. 86(3) (pp A27-A28) RIS download Bibtex download
  • Boult JKR, Bury JP, Bullock AJ, Campbell MJ, Taniere P, MacNeil S & Tselepis C (2005) Regulation of the MYC network in the progression to oesophageal adenocarcinoma. GUT, Vol. 54 (pp A87-A87) RIS download Bibtex download
  • Bullock AJ, Askew HE, Chapple, CR & MacNeil, S () Reducing the risks in the production of tissue engineered buccal mucosa for urethral reconstruction.. European Association of Urologists. Milan, Italy, 15 March 2013 - 19 March 2013. RIS download Bibtex download
  • Bullock AJ & Wray S () Metabolic inhibition in neonatal and adult guinea pig ureter.. Fetal and Neonatal Physiology Society. Arica, Chile, 14 August 1996 - 18 August 1996. RIS download Bibtex download
  • Bullock AJ & Wray S () pH regulation in neonate and adult guinea pig ureteric smooth muscle. Fetal and Neonatal Physiology Society. St. Margherita Ligure, Italy, 8 June 1997 - 11 June 1997. RIS download Bibtex download
  • Bullock AJ & Wray S () The effects of metabolic inhibition on force and intracellular calcium in guinea pig ureter.. The Physiology Society. Edinburgh, 2 July 1996 - 6 July 1996. RIS download Bibtex download