Dr Shamanthi Jayasooriya
MRCPCH, DTM&H, PhD, MRCGP, DFSRH
Academic Unit of Medical Education
NIHR Academic Clinical Lecturer
Full contact details
Academic Unit of Medical Education
Room 207B, Second Floor, Sam Fox House
Northern General Hospital
I am a NIHR Academic Clinical lecturer in primary care medicine and a General Practitioner based at Page Hall Medical Centre, a Deep End Clinical Research Cluster practice, in one of the most deprived and ethnically diverse areas of Sheffield.
My undergraduate medical training was completed at the University of Southampton in 2002. Prior to training in General Practice in Sheffield (2011-2016) I completed postgraduate training in Paediatrics in London and South Yorkshire (2004-2006). I was awarded Medical Research Council (MRC) PhD Scholarship (2007-2011) under the supervision of Professor Hilton Whittle (LSHTM) and Professor Alan Rickinson (Birmingham) to study immune responses to Epstein-Barr Virus in children in Sub-Saharan Africa based primarily at the MRC unit The Gambia. I subsequently returned to MRC The Gambia (2017-2018) and was primary study clinician on Tb Sequel, a multi-centre study exploring lung impairment post Tuberculosis infection.
- Research interests
My research interests centre around global Lung Health, with a focus on health implementation research around service provision for patients with Non-Communicable Chronic Lung Disease in Lower- and Middle- Income countries (LMICs).
I am also involved in exploring the environmental determinants of pre-term birth in LMICs as a research associate with the NIHR Global Health Research Group on Preterm Birth Intervention and Management (PRIME).
Overseas work and my patient contact in practice have driven my keen interest in exploring health inequalities and Lung health in marginalised groups within the UK with a focus on migrant populations.
- The burden of non-TB lung disease presenting to TB clinics in The Gambia: preliminary data in the Xpert® MTB/Rif era. Public Health Action, 9(4), 166-168.
- Early Virological and Immunological Events in Asymptomatic Epstein-Barr Virus Infection in African Children. PLOS Pathogens, 11(3). View this article in WRRO
- Plasmodium Infection Is Associated with Impaired Hepatic Dimethylarginine Dimethylaminohydrolase Activity and Disruption of Nitric Oxide Synthase Inhibitor/Substrate Homeostasis. PLOS Pathogens, 11(9), e1005119-e1005119.
- Revisiting the Effect of Acute P. falciparum Malaria on Epstein-Barr Virus: Host Balance in the Setting of Reduced Malaria Endemicity. PLoS ONE, 7(2), e31142-e31142.
- Distinct Roles for FOXP3+ and FOXP3− CD4+ T Cells in Regulating Cellular Immunity to Uncomplicated and Severe Plasmodium falciparum Malaria. PLoS Pathogens, 5(4), e1000364-e1000364.
- Teaching interests
I provided regular supervision of Registrars and Physicians Assistants while in clinical practice.
I teach on the Communicable Disease Control distance-learning module of the Masters in Public Health initially as an honorary clinical lecturer at the School of Health and Related Research (ScHARR). In addition I lecture on Key issues in Global Health: Non-Communicable diseases as part of the Masters in Global Health programme.
I have co-supervised a Masters Student at MRC Gambia exploring immunological markers of disease severity in Pulmonary Tuberculosis.
- Professional activities
Session Chair at European Congress on Tropical Medicine and International health (ECTMIH 2019).
Member of the British Thoracic Society (BTS) Global Lung Health Advisory Group.
Peer Review: I review papers for Transactions for the Royal Society of Tropical Medicine and Hygiene.
- Current projects
Following pilot work at MRC The Gambia on patients with Chronic Lung Disease future work is planned to explore the burden of non-communicable chronic lung disease presenting to district health Clinics in Zimbabwe. Patient pathway mapping and service exploration will be utilised to guide further context specific health implementation research. GCRF travel funds obtained.
Pump Prime GCRF 7K award for exploring the Environmental determinants of Pre-term Birth with PRIME NIHR global health research group.