Dr Paul Morris

BMedSci, MBChB, MRCP, PhD, PGCME, FHEA

Department of Infection, Immunity and Cardiovascular Disease

Senior Clinical Lecturer in Cardiology

paul.morris@sheffield.ac.uk
+44 114 215 9545

Full contact details

Dr Paul Morris
Department of Infection, Immunity and Cardiovascular Disease
The Medical School
Beech Hill Road
Sheffield
S10 2RX
Profile

I joined the University of Sheffield in 1998 to study Medicine. I quickly developed an interest in cardiology and research and intercalated a BMedSci degree investigating the role of testosterone in men with heart disease.

I graduated as a medical doctor in 2004, became a member of the Royal College of Physicians in 2007 and then held a number of fellowships and research grants (BHF, NIHR, MRC, WT).

I am currently a Senior Clinical Lecturer at the University of Sheffield and Honorary Cardiology Consultant at Sheffield Teaching Hospitals. I hold a Wellcome Trust Clinical Research Career Development Fellowship.

I am also Director for Clinical Translation at the Insigneo Institute for In Silico Medicine. As an interventional cardiologist, my areas of clinical interest include percutaneous coronary intervention (PCI) and coronary physiological assessment.

Research interests

My research interests are in computational modelling of cardiac physiology and heart disease. I am interested in the construction, development and validation of computational workflows which predict cardiac physiology.

My current work is focused on the development of models of intra-coronary physiology including pressure and flow. Our VIRTUheart™ model computes intracoronary physiology and virtual fractional flow reserve (vFFR) a marker of coronary artery disease significance and a guide to treatment.


Current Projects

  • British Heart Foundation. BHF Translational Award no TG/19/1/34451. How will virtual (computed) fractional flow reserve (vFFR) impact the management of coronary artery disease? (VIRTU-4). 2019. £295,258.
  • National Institute for Health Research, Invention for Innovation (i4i). Gunn JP, Morris PD, Hose DR, Lawford PV. ‘A prototype tool to calculate 'virtual' myocardial fractional flow reserve (vFFR) non-invasively (VIRTU-3)’. R/146986-11-1. £294,746.
  • Wellcome Trust Clinical Research Career Development Fellowship. Morris PD. Computational modelling to improve the assessment and management of patients with coronary artery disease. 2019. £570,000.
Image from the VIRTUheart™ workflow

Image from the VIRTUheart™ workflow. VIRTUheart predicts pressure and flow dynamics within coronary arteries. These data inform decisions about how to treat coronary artery disease with tablets, PCI (stenting) or bypass surgery. 

Publications

Show: Featured publications All publications

Journal articles

All publications

Journal articles

Chapters

Conference proceedings papers

  • Gosling R, Morris P, Lawford P, Hose R & Gunn J (2019) Virtual (computed) FFR and Virtual Coronary Intervention (VCI) vs angiography for guiding PCI: a virtual study.. Heart, Vol. 105(Suppl 6) (pp a45-a45). Manchester, UK, 3 June 2019 - 5 June 2019. View this article in WRRO RIS download Bibtex download
  • Son S, Gosling R, Morris P & Gunn J (2018) What will be the Impact of Virtual Coronary Physiology upon the Practice of Coronary Artery Bypass Grafting Surgery for Patients with Coronary Artery Disease?. International Journal of Surgery, Vol. 55 (pp S9-S9) RIS download Bibtex download
  • Morris P, Iqbal J & Gunn JP (2017) Restenosis in simultaneous kissing stents to treat unprotected left main stem coronary artery bifurcation disease: incidence and management. EUROPEAN HEART JOURNAL, Vol. 38 (pp 87-87) View this article in WRRO RIS download Bibtex download
  • Sciola MI, Morris PD, Lawford PV, Hose DR & Gunn JP (2017) A novel mathematical signal processing application which automates and improves the accuracy of FFR assessment. EUROPEAN HEART JOURNAL, Vol. 38 (pp 183-184) View this article in WRRO RIS download Bibtex download
  • Morris P, Zwierzak I, Lawford P, Sir D, Hose R & Gunn J (2015) 209 The Development and Validation of anin silicoModel of Coronary Arterial Physiology for Diagnostic Use. Heart, Vol. 101(Suppl 4) (pp A115.1-A115) RIS download Bibtex download
  • Cimen S, Hoogendoorn C, Morris PD, Gunn J & Frangi A (2014) Reconstruction of Coronary Trees from 3DRA Using a 3D+t Statistical Cardiac Prior. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, Vol. 2 (pp 619-626) RIS download Bibtex download
  • Çimen S, Hoogendoorn C, Morris PD, Gunn J & Frangi AF (2014) Reconstruction of coronary trees from 3DRA using a 3D+t statistical cardiac prior. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, Vol. 17 (pp 619-626) RIS download Bibtex download
  • Morris PD, Ryan DR, Lycett R, Morton AC, Lawford PV, Hose DR & Gunn J (2012) 021 Computer modelled coronary physiology and “virtual” fractional flow reserve from rotational angiography: Abstract 021 Figure 1. Heart, Vol. 98(Suppl 1) (pp A14.1-A14) RIS download Bibtex download
  • Morris PF, Morgan P & Ridal KA (2012) Metals fit for the twenty-first century: Processing for high performance applications. Ironmaking and Steelmaking, Vol. 39(4) (pp 236-243) RIS download Bibtex download
  • Morris PD, Ryan DM, Lycett R, Morton AC, Lawford PV, Hose DR & Gunn JP (2011) Virtual Coronary Physiology and Anatomy Derived From Rotational Angiography: The First Step. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol. 58(20) (pp B189-B189) RIS download Bibtex download
  • Altenkirch T, Morris P, Forsberg FN & Setzer A (2011) A Categorical Semantics for Inductive-Inductive Definitions.. CALCO, Vol. 6859 (pp 70-84) RIS download Bibtex download
  • Morris P & Dowdall S (2011) Computer-aided Self-assessment and Independent Learning in Higher Education.. CSEDU (2) (pp 139-142) RIS download Bibtex download
  • Chapman J, Dagand P-É, McBride C & Morris P (2010) The gentle art of levitation.. ICFP (pp 3-14) RIS download Bibtex download
  • Thackray R, Morris PF & Ridal K (2010) Alloys for critical applications. Ironmaking and Steelmaking, Vol. 37(4) (pp 242-250) RIS download Bibtex download
  • Altenkirch T & Morris P (2009) Indexed Containers.. LICS (pp 277-285) RIS download Bibtex download
  • Lichtenberg J, Morris P, Ecker K & Welch LR (2008) Discovery of Regulatory Elements in Oomycete Orthologs.. BIOCOMP (pp 34-38) RIS download Bibtex download
  • Morris P, Altenkirch T & Ghani N (2007) Constructing Strictly Positive Families.. CATS, Vol. 65 (pp 111-121) RIS download Bibtex download
  • Morris P (2006) A Structural Characterization of Temporal Dynamic Controllability.. CP, Vol. 4204 (pp 375-389) RIS download Bibtex download
  • Morris P, Silk N & Ridal K (2005) Quality steel - Advances in process control. Ironmaking and Steelmaking, Vol. 32(5) (pp 391-396) RIS download Bibtex download
  • Morris P, Altenkirch T & McBride C (2004) Exploring the Regular Tree Types.. TYPES, Vol. 3839 (pp 252-267) RIS download Bibtex download
  • Morris P, Beynon J & Ridal K (2004) Advances in the hot rolling of steels. Ironmaking and Steelmaking, Vol. 31(1) (pp 8-13) RIS download Bibtex download
  • Pugh PJ, Malkin CJ, Morris PD, Asif S, Jones RD, Jones TH & Channer KS (2003) Prevalence of hypogonadism in men with coronary artery disease. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol. 41(6) (pp 344A-344A) RIS download Bibtex download
  • Pugh PJ, Malkin CJ, Morris PD, Nettleship J, Jones RD, Jones TH & Channer KS (2003) Relation of testosterone with inflammatory cytokines in men with coronary artery disease. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol. 41(6) (pp 344A-344A) RIS download Bibtex download
  • MALKIN C (2003) 187 Testosterone replacement therapy improves ischaemic threshold and mood in hypogonadal men with angina. European Heart Journal, Vol. 24(5) (pp 20-20) RIS download Bibtex download
  • Morris P (2003) Keynote: Metrics Based Project Governance.. IEEE METRICS RIS download Bibtex download
  • Morris P, Norlin E, Glogoff S & Forger G (2001) The Academic Library's Role in Transmitting Cultural Heritage Using 21st Centuri Technology: The University of Arizona Libraries and the Cultural Community Collaboration Model.. ICHIM (1) (pp 375-383) RIS download Bibtex download
  • Masera M & Morris P (1998) Dependable Embedded Systems: The Challenges for Requirements Engineering.. REFSQ (pp 187-192) RIS download Bibtex download
  • Morris P, Masera M & Wilikens M (1998) Requirements Engineering and Industrial Uptake.. ICRE (pp 130-137) RIS download Bibtex download
  • Morris P, Masera M & Wilikens M (1997) Industrial Workshop on Requirements for R&D in Requirements Engineering.. RE (pp 41-41) RIS download Bibtex download
  • Duffy DA, MacNish C, McDermid JA & Morris P (1995) A Framework for Requirements Analysis Using Automated Reasoning. CAiSE, Vol. 932 (pp 68-81) RIS download Bibtex download
  • Morris P (1993) The Breakout Method for Escaping from Local Minima.. AAAI (pp 40-45) RIS download Bibtex download
  • Morris P & McDermid JA (1992) Formalizing and Validating Complex Security Requirements.. DBSec, Vol. A-21 (pp 113-124) RIS download Bibtex download
  • Morris P (1992) On the Density of Solutions in Equilibrium Points for the Queens Problem.. AAAI (pp 428-433) RIS download Bibtex download
  • Morris P & McDermid JA (1991) The Structure of Permissions: A Normative Framework for Access Rights.. DBSec, Vol. A-6 (pp 77-97) RIS download Bibtex download
  • Feldman R & Morris P (1990) Admissible Criteria for Loop Control in Planning.. AAAI (pp 151-157) RIS download Bibtex download
  • Morris P (1988) Stable Closures, Defeasible Logic and Contradiction Tolerant Reasoning.. AAAI (pp 506-511) RIS download Bibtex download
  • Morris P (1987) Curing Anomalous Extensions.. AAAI (pp 437-442) RIS download Bibtex download
  • Morris P & Nado R (1986) Representing Actions with an Assumption-Based Truth Maintenance System.. AAAI (pp 13-20) RIS download Bibtex download
  • Kibler DF & Morris P (1981) Don't Be Stupid.. IJCAI (pp 345-347) RIS download Bibtex download
  • Morris P & Sagalowicz D (1977) Managing Network Access to a Distributed Database.. Berkeley Workshop (pp 58-67) RIS download Bibtex download
Teaching interests

I enjoy teaching clinical cardiology to undergraduates and post-graduates. I teach clinical skills to medical students and doctors on the wards and in the clinic.

I have written textbooks and chapters of books focused on clinical and academic aspects of clinical cardiology. I also enjoy teaching about cardiac physiology and fluid dynamics modelling.

I have a Postgraduate Certificate in Medical Education and have recently become a Fellow of the Higher Education Academy.

Professional activities

Other professional activities and interests include public engagement with science and the development of assessments for clinical knowledge and skills.