Dr Margaret Paggiosi

BSc (Hons), PhD

Department of Oncology and Metabolism

Research Lead for Bone Densitometry

Research Fellow

+44 114 215 9697

Full contact details

Dr Margaret Paggiosi
Department of Oncology and Metabolism
Metabolic Bone Centre (Sorby Wing)
Northern General Hospital
Herries Road
S5 7AU

For enquiries, please contact - iicd-om-operational@sheffield.ac.uk

I am the Research Lead for Bone Densitometry for the Mellanby Centre for Bone Research, Academic Unit of Bone Metabolism, Department of Oncology and Metabolism, The University of Sheffield, UK.

I completed my undergraduate studies at Sheffield Hallam University, UK and attained a BSc Honours degree in Biomedical Technology. In 1998, I received my PhD in Exercise Physiology from Sheffield Hallam University.

In 1996, I joined the Department of Human Metabolism and Clinical Biochemistry, The University of Sheffield to work as a DXA Scanning Technician and Research Associate. I now hold the position of Research Fellow.

I am responsible for the provision of the Academic Unit of Bone Metabolism’s bone densitometry service to internal and external organisations and investigators.

I have considerable expertise in a wide variety of bone densitometry and image analysis techniques. I am the Radiation Protection Supervisor (RPS) for the bone imaging work conducted at the NIHR Clinical Research Facility at the Northern General Hospital, Sheffield.

I have published over 20 articles in peer-reviewed journals and present my work at national and international conferences.

Research interests

My current research interests include the evaluation and application of high-resolution peripheral quantitative computed tomography, the study of bone microstructural properties and strength and the evaluation of treatment effects using bone densitometry techniques.

I have considerable expertise in the field of vertebral fracture identification. Of particular interest currently is the development of a computer-assisted diagnostic tool to automate the reading of spine images, using the algorithm-based qualitative (ABQ) method, to provide an accurate and reliable means of identifying vertebral fractures.


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Journal articles

All publications

Journal articles

Conference proceedings papers


  • Arthritis Research UK Medical Technologies Proof of Concept Award. Development and Evaluation of a Functional Prototype for the Automated Identification of Osteoporotic Vertebral Fractures: VERDICT. Frangi AF (PI), Paggiosi MA (co-applicant), Eastell R, Pozo Soler J, Peel NFA, Jacques R. Project grant: April 2017 to March 2019.
  • Weston Park Hospital Cancer Charity Louise Victoria Craddock Memorial fund. Equipment Purchase: DXA Machine That Is Particularly Effective At Measuring Body Fat. Paggiosi MA (PI), Eastell R, Brown JE. Capital project grant: November 2016 to April 2017.
  • The University of Sheffield Innovation, Impact and Knowledge Exchange (IIKE) Award. Cal-CT: Optimising calcaneus microstructure measurements for the assessment of skeletal strength in osteoporosis. EV McCloskey (PI), Frangi AF, Metcalf LM, Paggiosi MA (co-applicant). Project grant: October 2015 to March 2017.
  • The University of Sheffield through the MRC Confidence in Concept Scheme. VERTEBRAL FRACTURE: Vertebral analysis and fracture risk assessment from 2D DXA scans. Eastell R (PI), Frangi AF, Paggiosi MA (co-applicant), Pozo Soler J. Project grant: July 2014 to June 2015
Teaching activities

I lecture on the Mellanby Centre for Bone Research ‘Identification of Vertebral Fractures’ training courses and on the Academic Unit of Bone Metabolism’s teaching course.

I perform ad hoc teaching including the practical aspects of bone imaging techniques, radiation protection to students and members of staff.

Professional activities and memberships

I am a member of the American Society for Bone and Mineral Research, the Society of Radiographers and a professional member of the National Osteoporosis Society.

I act as co-organiser and co-chair of the Allied Health Professional session for the European Calcified Tissue Society at their annual conferences.

I am a regular reviewer of articles for key journals including Osteoporosis International, the Journal of Clinical Densitometry and Bone.