Bone and joint
The bone and joint research theme brings together skills in different diseases: osteoporosis, osteo arthritis, osteogenesis imperfecta, bone metastases and holds an MRC-Arthritis Research UK Award (one of only two centres in the UK).
It hosts the only Chair in children’s bone disease in the UK and is home to the world-class Mellanby Bone Research Centre, as well as being a validated lab for bone biomarkers. It has state of the art facilities for preclinical and clinical studies.
Meet the team
- Professor Ilaria Bellantuono
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Email: i.bellantuono@sheffield.ac.uk
Research focussed on ways to reduce the onset of multiple age-related disease by preventing or reversing the ageing of stem cells using medicinal drugs.
- Professor Nick Bishop
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Email: n.j.bishop@sheffield.ac.uk
Research aims to improve outcomes for children with inherited and acquired bone diseases and understand better the factors contributing to fracture in apparently healthy children.
- Dr Stephanie Borg
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Email: s.borg@sheffield.ac.uk
- Dr Enrico Dall'Ara
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Email: e.dallara@sheffield.ac.uk
Research to develop and validate computational models for the prediction of bone strength and risk of fracture in healthy and disease, applied to both pre-clinical and clinical studies.
- Professor Richard Eastell
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Email: r.eastell@sheffield.ac.uk
Research focusses on osteoporosis - studying the epidemiology, pathogenesis, diagnosis and treatment of the disease.
- Dr Catarina Henriques
- Professor Eugene McCloskey
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Email: e.v.mccloskey@sheffield.ac.uk
Metabolic bone diseases - vertebral fracture definition, osteoporosis epidemiology as well as non-invasive assessments of bone strength and fracture risk.
- Professor Amaka Offiah
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Email: a.offiah@sheffield.ac.uk
Optimisation of current techniques and development of novel methods of distinguishing brittle from normal bones, in understanding the mechanisms of accidental injury in children, in developing objective imaging biomarkers and normative data for the paediatric musculoskeletal system including post-mortem imaging and in diagnosing fractures in the Emergency Department.
- Dr Jennifer Walsh
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Email: j.walsh@sheffield.ac.uk
Research interests are in bone microarchitecture in skeletal maturation and ageing, the interactions of fat and bone, and treatment of osteoporosis and other metabolic bone diseases.
- Professor Mark Wilkinson
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Email: j.m.wilkinson@sheffield.ac.uk
Research interests include: Patient responses to joint prostheses and their modulation, genetics of bone and joint development and arthritis, metabolic bone disease, surrogate outcome markers for implant performance and failure, and clinical outcomes measurement after joint replacement.