Bone and joint

The bone and joint research theme brings together skills in different diseases: osteoporosis, osteo arthritis, osteogenesis imperfecta, bone metastases and holds an MRC-Arthritis Research UK Award (one of only two centres in the UK).

An image of a bone

It hosts the only Chair in children’s bone disease in the UK and is home to the world-class Mellanby Bone Research Centre, as well as being a validated lab for bone biomarkers. It has state of the art facilities for preclinical and clinical studies.

Meet the team

Professor Ilaria Bellantuono

Email: i.bellantuono@sheffield.ac.uk

Research focussed on ways to reduce the onset of multiple age-related disease by preventing or reversing the ageing of stem cells using medicinal drugs.

Find out more

Professor Nick Bishop

Email: n.j.bishop@sheffield.ac.uk

Research aims to improve outcomes for children with inherited and acquired bone diseases and understand better the factors contributing to fracture in apparently healthy children.

Find out more

Dr Enrico Dall'Ara

Email: e.dallara@sheffield.ac.uk

Research to develop and validate computational models for the prediction of bone strength and risk of fracture in healthy and disease, applied to both pre-clinical and clinical studies.

Find out more

Professor Richard Eastell

Email: r.eastell@sheffield.ac.uk

Research focusses on osteoporosis - studying the epidemiology, pathogenesis, diagnosis and treatment of the disease.

Find out more

Professor Eugene McCloskey

Email: e.v.mccloskey@sheffield.ac.uk

Metabolic bone diseases - vertebral fracture definition, osteoporosis epidemiology as well as non-invasive assessments of bone strength and fracture risk.

Find out more

Dr Amaka Offiah

Email: a.offiah@sheffield.ac.uk

Optimisation of current techniques and development of novel methods of distinguishing brittle from normal bones, in understanding the mechanisms of accidental injury in children, in developing objective imaging biomarkers and normative data for the paediatric musculoskeletal system including post-mortem imaging and in diagnosing fractures in the Emergency Department.

Find out more

Professor Tim Skerry

Email: t.skerry@sheffield.ac.uk

The main focus of the lab is now on development of small molecule antagonists of the AM2 adrenomedullin receptor.

Find out more

Dr Jennifer Walsh

Email: j.walsh@sheffield.ac.uk

Research interests are in bone microarchitecture in skeletal maturation and ageing, the interactions of fat and bone, and treatment of osteoporosis and other metabolic bone diseases.

Find out more

Professor Mark Wilkinson

Email: j.m.wilkinson@sheffield.ac.uk

Research interests include: Patient responses to joint prostheses and their modulation, genetics of bone and joint development and arthritis, metabolic bone disease, surrogate outcome markers for implant performance and failure, and clinical outcomes measurement after joint replacement.

Find out more

Flagship institutes

The University’s four flagship institutes bring together our key strengths to tackle global issues, turning interdisciplinary and translational research into real-world solutions.