Dr Laura Flight

MMath, MSc, PhD

School of Health and Related Research

Research Associate

+44 114 222 0698

Full contact details

Dr Laura Flight
School of Health and Related Research
Room 1025
Regent Court (ScHARR)
30 Regent Street
S1 4DA

I joined Design, Trials and Statistics section of ScHARR in 2013 as an NIHR Research Methods Fellow. This fellowship focussed on the use of adaptive study designs in emergency medicine clinical trials. This research formed part of my dissertation for an MSc in Statistics with Medical Applications at the University of Sheffield. Prior to this I graduated from the University of Sheffield with a MMath (Hons) in 2013.

In 2016 I was awarded an NIHR Doctoral Research Fellowship exploring the use of health economics in the design, monitoring and analysis of adaptive clinical trials. More information about this fellowship can be found here.

In January 2019 I moved to HEDS as a Research Associate in Health Economics and Statistics. I am also a Statistics Adviser for the Research Design Service, Yorkshire and Humber.

I am currently involved in the following projects:

  • EcoNomics of Adaptive Clinical Trials (ENACT)
  • MAGIC - Melatonin for Anxiety prior to General anaesthesia In Children
  • STOP-OHSS: A feasibility study and randomised controlled trial, with internal pilot, to assess the clinical and cost-effectiveness of earlier active management of OHS
Research interests
  • Methods for undertaking health economic evaluations alongside clinical trials.
  • Value of information analysis.
  • The use of health economics in the design, monitoring and analysis of adaptive clinical trials.

Show: Featured publications All publications

Journal articles

All publications

Journal articles

Conference proceedings papers


  • Forster M, Flight L, Corbacho B, Keding A, Ronaldson S, Tharmanathan P, Welch C, Brennan A & Chick S (2021) Report for the EcoNomics of Adaptive Clinical Trials (ENACT) project: Application of a Bayesian Value-Based Sequential Model of a Clinical Trial to the CACTUS and HERO Case Studies (with Guidance Material for Clinical Trials Units) View this article in WRRO RIS download Bibtex download


  • Candlish J, Teare D, Cohen J, Dimairo M, Flight L, Mandefield L & Walters S (2017) Methods to analyse partially nested randomised controlled trials. RIS download Bibtex download
  • Walters S, Lee E, Flight L, Mandefield L, Dimario M & Allison A (2015) Analysis and reporting of individually randomised controlled trials with clustering in one arm only: how should we do it?. RIS download Bibtex download