Professor Stephen Walters BSc, PGCE, MSc, PhD, CStat.

Professor of Medical Statistics and Clinical Trials

Photograph of Stephen Walters

The University of Sheffield
Regent Court
30 Regent Street
S1 4DA

Tel: (+44) (0)114 222 0730
Fax: (+44) (0)114 272 4095




I graduated with a degree in Mathematics and Economics. This was followed by a PGCE and an MSc in Medical Statistics and Information Technology. My PhD involved using computer intensive statistical methods for estimating sample sizes and analysing quality of life outcomes. I joined ScHARR in January 1995. I was promoted to Senior Lecturer in 2003; Reader in 2008 and to a Personal Chair in 2009. I was the first Director of the Design, Trials and Statistics section in ScHARR from 2012-18.

I am a Chartered Statistician with over 24 years’ experience of health services research and technology assessment. The main focus of my research has been in the design, analysis and reporting of trials of complex interventions; and the design, assessment, analysis and interpretation of patient reported outcomes in clinical trials. I work with clinicians from a variety of backgrounds to develop pragmatic clinical trial designs to capture the effectiveness and cost-effectiveness of a variety of health technologies. I have been co-investigator for more than 20 RCTs of non-pharmaceutical interventions.

I am currently an National Institute for Health Research (NIHR) Senior Investigator.  I have been a  member of the NIHR Health Technology Assessment (HTA) Clinical Evaluation and Trials Board (2011-17) and the East Midlands Regional Funding Committee for the NIHR Research for Patient Benefit Pogramme (2011-2012). I have also been a member of the National Institute for Health and Care Excellence (NICE) Public Health Interventions Advisory Committee (2008-2013).

I have co-authored over 286 publications (including 176 in refereed journals and 4 books, with over 21,000 copies sold). The majority of my  peer-reviewed journal articles have been applied research, with the emphasis on the evaluation of new services. I have been a co-applicant, statistical advisor and collaborator on over 57 health services research projects.

Research Interests

My research interests are

Teaching Interests

I have developed several courses on teaching medical statistics to medical and health science students, clinicians and allied health professionals. I have also co-authored three textbooks: 'Medical Statistics: A Textbook for the Health Sciences' ; 'How to Display Data' and 'How to Design, Analyse and Report Cluster Randomised Trials in Medicine and Health Related Research'.

I co-ordinate and teach on HAR6035 `An Introduction to Statistics and Critical Appraisal´ module on the Master of Public Health programme and contribute to the distance learning version (HAR6042). I also teach on several other courses including: HAR674 Randomised Controlled Trials; MAS6061 Epidemiology; MAS6062 Further Clinical Trials.

Professional activities

  • Independent statistician member on several data and safety monitoring committees. 
  • Member of the Editorial Board for the journal of Health and Quality of Life Outcomes.
  • Member of the Irish Health Research Board.
  • NIHR Senior Investigator.

Current projects

  • NIHR PGFaR Bridging the age gap in breast cancer. Improving outcomes for older women. Co-applicant (PI: Dr L. Wyld, Prof. M. Read). 2012-2017 £1,705,273
  • ACtiF Development and evaluation of an intervention to support Adherence to treatment in adults with Cystic Fibrosis. Co-applicant. (PI: Dr M Wildman). 2014-2019. £1,981,622
  • NIHR HTA Scratch A multi-centre RCT of Induced Endometrial Trauma in Women undergoing first time IVF. Co-applicant. (PI: Mr M Metwally). 2015-2020 £1,347,586
  • NIHR HTA JtD Journeying Through Dementia; RCT of clinical and cost-effectiveness.  2015-2019. Co-applicant. (PI: Professor Gail Mountain). £1,964,310
  • VASCULAR The Design, Development, Commissioning and Evaluation of Patient Focused Vascular Services. Co-applicant.  (PI: Prof J Michaels). 2013-2018. £1,866,367
  • NIHR Research methods Fellowships and Internships NIHR-RMFI. Co-applicant. (PI: Professor Jon Nicholl).2015-2017. £87,376
  • PREeMPT Is it feasible to conduct a randomised controlled trial of pre transplant exercise (pre-habilitation) for multiple myeloma patients awaiting autologous stem cell transplantation (PREempt).  Co-applicant.  (PI: Professor Sue Mawson). 2016-2020. £179,361

View full list of Stephen Walters' publications


Stephen Walters is based in the Design, Trials & Statistics Section.


  • Campbell MJ & Walters SJ (2014) How to Design, Analyse and Report Cluster Randomised Trials in Medicine and Health Related Research. John Wiley & Sons Ltd.. RIS download Bibtex download

Journal articles