Nyasha Mafirakureva
School of Medicine and Population Health
Research Fellow
+44 114 225 9137
Full contact details
School of Medicine and Population Health
Regent Court (ScHARR)
30 Regent Street
Sheffield
S1 4DA
- Profile
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I joined the Health Economics and Decision Science (HEDS) section of the School of Health and Related Research (ScHARR) as Research Fellow in Health Economics and Decision Modelling in January 2019. I’m currently working on economic evaluation of clinical trials evaluating various paediatric tuberculosis interventions in lower-middle income countries (LMIC). Previously I worked at the University of Bristol, UK where I was involved in evaluating the impact and cost-effectiveness of interventions for hepatitis C virus in low and middle-income countries. Since 2011, I have been carrying out economic evaluation projects in Cambodia, Cameroon, Ireland, Kenya, Myanmar, Pakistan, Uganda, South Africa and Zimbabwe.
- Research interests
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My research interests include economic evaluations of interventions to improve infectious disease control and decision-analytic modelling for cost-effectiveness analysis.
Current Projects
- Cap-TB and TB SPEED projects on interventions for paediatric TB (UNITAID)
- Fractures in Sub-Saharan Africa: epidemiology, economic impact and ethnography (FRACTURES-E3) – Wellcome Trust
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- Cost-effectiveness of community-based household tuberculosis contact management for children in Cameroon and Uganda: a modelling analysis of a cluster-randomised trial. The Lancet Global Health, 11(12), e1922-e1930. View this article in WRRO
- Cost-effectiveness analysis of interventions to improve diagnosis and preventive therapy for paediatric tuberculosis in 9 sub-Saharan African countries: A modelling study. PLOS Medicine, 20(9). View this article in WRRO
- The healthcare system costs of hip fracture care in South Africa. Osteoporosis International, 34(4), 803-813. View this article in WRRO
- Xpert ultra stool testing to diagnose tuberculosis in children in Ethiopia and Indonesia: a model-based cost-effectiveness analysis. BMJ Open, 12(7).
- The global impact of household contact management for children on multidrug-resistant and rifampicin-resistant tuberculosis cases, deaths, and health-system costs in 2019: a modelling study. The Lancet Global Health, 10(7), E1034-E1044. View this article in WRRO
- An intensive model of care for hepatitis C virus screening and treatment with direct‐acting antivirals in people who inject drugs in Nairobi, Kenya : a model‐based cost‐effectiveness analysis. Addiction, 117(2), 411-424.
- Cost-effectiveness of mass screening for Hepatitis C virus among all inmates in an Irish prison. International Journal of Drug Policy, 96.
- Cost‐effectiveness of screening and treatment using direct‐acting antivirals for chronic Hepatitis C virus in a primary care setting in Karachi, Pakistan. Journal of Viral Hepatitis, 28(2), 268-278.
- Cost and cost‐effectiveness of a simplified treatment model with direct‐acting antivirals for chronic hepatitis C in Cambodia. Liver International, 40(10), 2356-2366.
- Effects and cost of different strategies to eliminate hepatitis C virus transmission in Pakistan: a modelling analysis. The Lancet Global Health, 8(3), e440-e450.
- Cost effectiveness of adding nucleic acid testing to hepatitis
B , hepatitisC , and human immunodeficiency virus screening of blood donations inZ imbabwe. Transfusion, 56(12), 3101-3111.
- A systematic approach for reviewing research capacity within Zimbabwe's national blood service. ISBT Science Series, 11(2), 110-117.
- Health-related quality of life in HIV/AIDS patients on antiretroviral therapy at a tertiary care facility in Zimbabwe. AIDS Care, 28(7), 904-912.
- The costs of producing a unit of blood in
Z imbabwe. Transfusion, 56(3), 628-636.
- Profiles of blood and blood component transfusion recipients in Zimbabwe. Blood Transfusion, 13(4), 600-609.
Preprints
All publications
Journal articles
- Hip fracture care in Zimbabwe. Bone & Joint Open, 6(10), 1179-1189. View this article in WRRO
- Evaluating the health impact, health-system costs and cost-effectiveness of using TrueNat on stool samples compared to usual care for the diagnosis of paediatric tuberculosis in primary care settings: a modelling analysis. PLOS Global Public Health, 5(6). View this article in WRRO
- Cost-effectiveness of tuberculosis infection screening at first reception into English prisons: a model-based analysis. EClinicalMedicine, 83. View this article in WRRO
- Treatment decision algorithms for tuberculosis screening and diagnosis in children below 5 years hospitalised with severe acute malnutrition: a cost-effectiveness analysis. eClinicalMedicine, 83. View this article in WRRO
- Cost-effectiveness of screening and treating chronic hepatitis C virus infection in Zimbabwe. International Journal of Environmental Research and Public Health, 22(4). View this article in WRRO
- Cost-effectiveness of integrating paediatric tuberculosis services into child healthcare services in Africa: a modelling analysis of a cluster-randomised trial. BMJ Global Health, 9. View this article in WRRO
- Household contact management and preventive treatment for drug-resistant tuberculosis. The Lancet Global Health, 12(9), e1387-e1388. View this article in WRRO
- A cost analysis of a simplified model for HCV screening and treatment at a tertiary hospital in Zimbabwe. Expert Review of Pharmacoeconomics & Outcomes Research, 24(5), 687-695.
- A situational and stakeholder analysis of health technology assessment in Zimbabwe. International Journal of Technology Assessment in Health Care, 40(1). View this article in WRRO
- Cost-effectiveness and budget impact of decentralising childhood tuberculosis diagnosis in six high tuberculosis incidence countries: a mathematical modelling study. eClinicalMedicine, 70. View this article in WRRO
- Integration of HIV testing in a community intervention for tuberculosis screening among household contacts of patients with tuberculosis in Cameroon and Uganda. JAIDS Journal of Acquired Immune Deficiency Syndromes, 95(5), 431-438. View this article in WRRO
- Household costs incurred under community- and facility-based service-delivery models of tuberculosis preventive therapy for children: a survey in Cameroon and Uganda. Journal of Global Health Reports, 7. View this article in WRRO
- Household costs incurred when seeking and receiving paediatric tuberculosis services: a survey in Cameroon and Kenya. Journal of Global Health Reports, 7. View this article in WRRO
- Effectiveness of a community-based approach for the investigation and management of children with household tuberculosis contact in Cameroon and Uganda: a cluster-randomised trial. The Lancet Global Health, 11(12), e1911-e1921.
- Cost-effectiveness of community-based household tuberculosis contact management for children in Cameroon and Uganda: a modelling analysis of a cluster-randomised trial. The Lancet Global Health, 11(12), e1922-e1930. View this article in WRRO
- Cost-effectiveness analysis of interventions to improve diagnosis and preventive therapy for paediatric tuberculosis in 9 sub-Saharan African countries: A modelling study. PLOS Medicine, 20(9). View this article in WRRO
- Evaluating change in a pressured healthcare system: a cross-sectional study of implementation outcomes using routine data indicators and proxies. Implementation Science Communications, 4(1). View this article in WRRO
- Fractures in sub-Saharan Africa: epidemiology, economic impact and ethnography (Fractures-E3): study protocol [version 1; peer review: 2 approved]. Wellcome Open Research, 8.
- The healthcare system costs of hip fracture care in South Africa. Osteoporosis International, 34(4), 803-813. View this article in WRRO
- OP28 Health technology assessment: A situation analysis of Zimbabwe. International Journal of Technology Assessment in Health Care, 38(Suppl 1), S11-S12. View this article in WRRO
- Modelling the impact of HIV and hepatitis C virus prevention and treatment interventions among people who inject drugs in Kenya. AIDS, 36(15), 2191-2201. View this article in WRRO
- Xpert ultra stool testing to diagnose tuberculosis in children in Ethiopia and Indonesia: a model-based cost-effectiveness analysis. BMJ Open, 12(7).
- The global impact of household contact management for children on multidrug-resistant and rifampicin-resistant tuberculosis cases, deaths, and health-system costs in 2019: a modelling study. The Lancet Global Health, 10(7), E1034-E1044. View this article in WRRO
- Feasibility of a randomized clinical trial evaluating a community intervention for household tuberculosis child contact management in Cameroon and Uganda. Pilot and Feasibility Studies, 8. View this article in WRRO
- An intensive model of care for hepatitis C virus screening and treatment with direct‐acting antivirals in people who inject drugs in Nairobi, Kenya : a model‐based cost‐effectiveness analysis. Addiction, 117(2), 411-424.
- Cost-effectiveness of mass screening for Hepatitis C virus among all inmates in an Irish prison. International Journal of Drug Policy, 96.
- Progress on the elimination of viral hepatitis in Zimbabwe: A review of the policies, strategies and challenges. Journal of Viral Hepatitis, 28(7), 994-1002.
- Cost‐effectiveness of screening and treatment using direct‐acting antivirals for chronic Hepatitis C virus in a primary care setting in Karachi, Pakistan. Journal of Viral Hepatitis, 28(2), 268-278.
- Cost and cost-effectiveness of a real-world HCV treatment program among HIV-infected individuals in Myanmar. BMJ Global Health, 6(2).
- Cost and cost‐effectiveness of a simplified treatment model with direct‐acting antivirals for chronic hepatitis C in Cambodia. Liver International, 40(10), 2356-2366.
- Integrating pediatric TB services into child healthcare services in Africa: study protocol for the INPUT cluster-randomized stepped wedge trial. BMC Public Health, 20(1).
- Effects and cost of different strategies to eliminate hepatitis C virus transmission in Pakistan: a modelling analysis. The Lancet Global Health, 8(3), e440-e450.
- Fragility fractures in sub-Saharan Africa : time to break the myth. The Lancet Global Health, 7(1), e26-e27.
- Cost effectiveness of adding nucleic acid testing to hepatitis
B , hepatitisC , and human immunodeficiency virus screening of blood donations inZ imbabwe. Transfusion, 56(12), 3101-3111.
- Erratum. Transfusion, 56(7), 1920-1920.
- A systematic approach for reviewing research capacity within Zimbabwe's national blood service. ISBT Science Series, 11(2), 110-117.
- Health-related quality of life in HIV/AIDS patients on antiretroviral therapy at a tertiary care facility in Zimbabwe. AIDS Care, 28(7), 904-912.
- The costs of producing a unit of blood in
Z imbabwe. Transfusion, 56(3), 628-636.
- Profiles of blood and blood component transfusion recipients in Zimbabwe. Blood Transfusion, 13(4), 600-609.
- Incidence and pattern of 12 years of reported transfusion adverse events in Zimbabwe: A retrospective analysis. Blood Transfusion, 12(3), 362-367.
- Population Pharmacokinetic-Pharmacodynamic Modeling of Haloperidol in Patients With Schizophrenia Using Positive and Negative Syndrome Rating Scale. Journal of Clinical Psychopharmacology, 33(6), 731-739.
- Integrating Hepatitis C Care for Opioid Substitution Treatment Patients Attending General Practice: Feasibility, Clinical, and Cost-Effectiveness Analysis. Interactive Journal of Medical Research, 11(2), e35300-e35300.
Book chapters
- Humanitarian medical logistics and operations management In Mkansi M, Amadi-Echendu A & De Villiers A (Ed.), Emerging Issues in Operations and Supply Chain Management Hatfield, South Africa: Van Schaik Publishers.
Conference proceedings
- THE ECONOMIC IMPACT OF HIP FRACTURE IN ZIMBABWE AND SOUTH AFRICA. AGING CLINICAL AND EXPERIMENTAL RESEARCH, Vol. 36 (pp S92-S92)
- AGE- AND SEX-SPECIFIC INCIDENCE RATES AND FUTURE PROJECTIONS FOR HIP FRACTURES IN ZIMBABWE. AGING CLINICAL AND EXPERIMENTAL RESEARCH, Vol. 36 (pp S295-S295)
- Assessment of the Costs and outcomes of Antiretroviral Therapy In Adult Outpatients at a Tertiary Hospital In Harare, Zimbabwe. Value in Health, Vol. 18(3) (pp A236-A236)
- The Average Unit Production Cost of Blood in Zimbabwe from a Provider's Perspective. TRANSFUSION, Vol. 54 (pp 237A-237A)
- THE EVALUATION OF BLOOD DONOR DEFERRAL CAUSES IN ZIMBABWE. VOX SANGUINIS, Vol. 105 (pp 97-97)
Posters
- Modelling the cost of hepatitis C virus transmission in Pakistan.
- Cost-effectiveness of screening and treatment using direct-acting antivirals for chronic hepatitis C virus in low- and middle-income settings.
- Cost-effectiveness of mass screening for HCV in an Irish prison.
- Comparison of costs of different HCV screening and linkage to care interventions across Europe.
Preprints
- Global estimates of tuberculosis incidence during pregnancy and postpartum: a rapid review and modelling analysis, Cold Spring Harbor Laboratory.
- Cost-effectiveness of tuberculosis infection screening at first reception into English prisons: a model-based analysis, Cold Spring Harbor Laboratory.
- Treatment decision algorithms for tuberculosis screening and diagnosis in children below 5 years hospitalised with severe acute malnutrition: a cost-effectiveness analysis, Cold Spring Harbor Laboratory.
- Cost-effectiveness and budget impact of decentralising childhood tuberculosis diagnosis: a mathematical modelling study in six high tuberculosis incidence countries, Cold Spring Harbor Laboratory.
- Evaluating Change in a Degraded Healthcare System: A Cross-Sectional Study of Implementation Outcomes using Routine Data Indicators and Proxies., Springer Science and Business Media LLC.
- Modelling the Impact of Prevention and Treatment Interventions on HIV and Hepatitis C Virus Transmission Among People Who Inject Drugs in Kenya, Cold Spring Harbor Laboratory.
- Cost-effectiveness of community-based household tuberculosis contact management for children in Cameroon and Uganda: a modelling analysis of a cluster-randomised trial. The Lancet Global Health, 11(12), e1922-e1930. View this article in WRRO
- Teaching interests
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Economic Evaluation and Health Care Financing
Dissertation supervision
- Professional activities and memberships
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Member of International Society for Pharmacoeconomics and Outcome Research (ISPOR).
Member of International Society for Pharmacoeconomics and Outcome Research (ISPOR) South African Chapter.
Member of Public Health Association of South Africa.