Professor Claire Lewis

Clinical Medicine, School of Medicine and Population Health

Professor of Molecular & Cellular Pathology
+44 114 215 9012

Full contact details

Professor Claire Lewis
Clinical Medicine, School of Medicine and Population Health
Floor E
The Medical School
Beech Hill Road
S10 2RX

For enquiries please contact -

After completing my DPhil (PhD) in the Department of Physiology, Anatomy and Genetics in Oxford in 1986, I held two postdoctoral positions and a Lectureship in the Medical School there before moving to join the Medical School in Sheffield in 1996.  I currently hold a Personal Chair in Molecular & Cellular Pathology and head a team of pre and postdoctoral scientists.

I was awarded a DSc by Oxford University in 2006 for my contribution to the field of tumour inflammation research.  During my career, my group has filed numerous patent applications and worked with various collaborators in the commercial sector.  I also enjoyed running a spin-out company and was delighted to receive Cancer Research Horizon's Woman Entrepreneur Award in 2022.

Research interests

Our research is focused mainly on the role of inflammatory cells called macrophages in tumour progression and responses to conventional anti-cancer treatments like chemotherapy and irradiation.

We have also developed ways of using these cells to target therapeutic genes and viruses to tumours. Our work was reported in the national press (,) and is mainly funded by grants from Breast Cancer Now, Prostate Cancer UK, The European Union, Cancer Research UK and Team Verrico.


Show: Featured publications All publications

Journal articles

All publications


  • Staton C, Lewis CE & Bicknell R (2007) Angiogenesis Assays: A Critical Appraisal of Current Techniques. Wiley-Blackwell. RIS download Bibtex download

Journal articles


  • Staton CA & Lewis CE (2006) Alphastatin: a pluripotent inhibitor of activated endothelial cells In Siemann DW (Ed.), Vascular-targeted therapies in oncology (pp. 205-220). Wiley-Blackwell RIS download Bibtex download
  • Burke B, Lewis JS & Lewis CE (2000) Cytoklne production by indlvldual cells, Cytokine Cell Biology (pp. 147-171). Oxford University PressOxford RIS download Bibtex download

Conference proceedings papers


Research group

Group Members

  • Professor Claire Lewis
  • Dr Mohammed Ridha (Postdoc)
  • Dr Haider Al-Janabi (Postdoc)
  • Katy Moyes (Postgraduate RA)
  • Richard Allen (PhD student)
Teaching interests
  • Acute and chronic inflammation
  • Angiogenesis in human diseases
  • Cancer
Professional activities and memberships


  • Member of the Editorial Board, Frontiers in Immunology.
  • Member of the Editorial Board, Cancer Research.
  • Member of the Editorial Board, Cancers.
  • Member of the Editorial Board, Journal of Clinical Investigation Insight.
  • Member of the Editorial Board, OncoImmunology.
  • Member of the Editorial Board, International Journal of Cancer.
  • Associate Editor, International Journal of Experimental Pathology.

Grant Awarding Bodies

  • Member, MRC/NIHR UK-US Cancer Skills Development Panel (2023 -  present).
  • Member, MRC Molecular & Cellular Medicines Board (2018-2022).
  • Member, PCUK Research Advisory Committee (2019-2022).
  • Member, Quinquennial Review Panel, MRC Human Immunology Unit, Oxford, Nov. 2016.
  • Member, Quinquennial Review Panel, Breast Cancer Now Manchester Research Unit, Feb. 2016.
  • Member, Senior Investigator Awards Committee, The Wellcome Trust, (2013).
  • Member of 3 Scientific Advisory Boards: ‘Cancer Immunotherapy’, Tumour Inflammation’ and ‘Metastasis’ for the Cancer Section of EU Framework 7 (2007- present).
  • Member, International Science Evaluation Panel (for biology, medicine and health), The Research Council, Norway (2011).
  • Member, AACR Basic Cancer Research Grants Scientific Review Committee (2010).
  • Chair, BBSRC Review Panel in Interdisciplinary Research (2005).
  • MRC College of Experts - Molecular and Cellular Medicine Board, (2004-current).
  • EPSRC Peer Review College (2006-2009).
  • Member, Scientific Advisory Board, Breast Cancer Campaign (1999-2002).