Dr Helen Marshall

PhD

Clinical Medicine, School of Medicine and Population Health

Research Staff Scientist

H.Marshall@sheffield.ac.uk
+44 114 215 9145

Polaris

Full contact details

Dr Helen Marshall
Clinical Medicine, School of Medicine and Population Health
Polaris
18 Claremont Crescent
Sheffield
S10 2TA

Profile

For enquiries please contact - ClinMed-Operational@sheffield.ac.uk

I have worked on the development and application of hyperpolarised gas and proton lung MRI at the University of Sheffield since 2009. Previously I was a post-doctoral fellow at the University of Toronto working on dynamic contrast-enhanced breast imaging. I have a PhD in MRI Physics and a BSc in Physics from Imperial College London.

Research interests

My research interests are focused on the application of MR imaging techniques in patients with lung disease. Projects that I have worked on include:

early detection of lung disease in children with cystic fibrosis
visualisation of collateral and delayed ventilation in patients with advanced chronic obstructive pulmonary disease (COPD)
imaging of ventilation response to therapies in patients with asthma and COPD
visualisation of ventilation and perfusion matching in patients with chronic thromboembolic pulmonary hypertension, asthma and COPD
imaging ventilation and microstructural changes in young adults with congenital diaphragmatic hernia

I am involved in clinical research study design and delivery, devising MR acquisition protocols and image computing workflows, and performing data analysis and interpretation. I helped to establish and am active in maintaining our clinical hyperpolarised gas lung imaging service.

Publications

Show: Featured publications All publications

Featured publications

Journal articles

Mussell G, Marshall H, Smith L, Biancardi A, Hughes P, Capener D, Bray J, Swift A, Rajaram S, Condliffe A , Collier G et al (2021) Xenon ventilation MRI in difficult asthma; initial experience in a clinical setting. European Respiratory Journal, 7(3). View this article in WRRO
Stewart NJ, Smith LJ, Chan H-F, Eaden JA, Rajaram S, Swift AJ, Weatherley ND, Biancardi A, Collier GJ, Hughes D , Klafkowski G et al (2021) Lung MRI with hyperpolarised gases : current & future clinical perspectives. The British Journal of Radiology, 94. View this article in WRRO
Marshall H, Stewart N, Chan H-F, Rao M, Norquay G & Wild J (2021) In vivo methods and applications of xenon-129 magnetic resonance. Progress in Nuclear Magnetic Resonance Spectroscopy, 122, 42-62. View this article in WRRO
Marshall H, Kenworthy C, Horn F, Thomas S, Swift A, Siddiqui S, Brightling C & Wild J (2020) Peripheral and proximal lung ventilation in asthma; short-term variation and response to bronchodilator. Journal of Allergy and Clinical Immunology. View this article in WRRO
Marshall H, Collier GJ, Johns CS, Chan H, Norquay G, Lawson RA & Wild JM (2019) Imaging Collateral Ventilation in Patients With Advanced Chronic Obstructive Pulmonary Disease: Relative Sensitivity of 3 He and 129 Xe MRI. Journal of Magnetic Resonance Imaging, 49(4), 1195-1197. View this article in WRRO
Smith L, Marshall H, Aldag I, Horn F, Collier G, Hughes D, West N, Horsley A, Taylor CJ & Wild J (2018) Longitudinal Assessment of Children with Mild CF Using Hyperpolarised Gas Lung MRI and LCI. American Journal of Respiratory and Critical Care Medicine, 197(3). View this article in WRRO
Marshall H, Horsley A, Taylor CJ, Smith L, Hughes D, Horn FC, Swift AJ, Parra-Robles J, Hughes PJ, Norquay G , Stewart NJ et al (2017) Detection of early subclinical lung disease in children with cystic fibrosis by lung ventilation imaging with hyperpolarised gas MRI. Thorax, 72(8), 760-762. View this article in WRRO
Spoel M, Marshall H, IJsselstijn H, Parra-Robles J, van der Wiel E, Swift AJ, Rajaram S, Tibboel D, Tiddens HAWM & Wild JM (2016) Pulmonary ventilation and micro-structural findings in congenital diaphragmatic hernia. Pediatric Pulmonology, 51(5), 517-524.
Marshall H, Kiely DG, Parra-Robles J, Capener D, Deppe MH, van Beek EJR, Swift AJ, Rajaram S, Hurdman J, Condliffe R , Elliot CA et al (2014) Magnetic Resonance Imaging of Ventilation and Perfusion Changes in Response to Pulmonary Endarterectomy in Chronic Thromboembolic Pulmonary Hypertension. American Journal of Respiratory and Critical Care Medicine, 190(5), e18-e19. View this article in WRRO
Marshall H, Parra-Robles J, Deppe MH, Lipson DA, Lawson R & Wild JM (2014) (3)He pO2 mapping is limited by delayed-ventilation and diffusion in chronic obstructive pulmonary disease.. Magn Reson Med, 71(3), 1172-1178. View this article in WRRO
Marshall H, Deppe MH, Parra-Robles J, Hillis S, Billings CG, Rajaram S, Swift A, Miller SR, Watson JH, Wolber J , Lipson DA et al (2012) Direct visualisation of collateral ventilation in COPD with hyperpolarised gas MRI.. Thorax, 67(7), 613-617. View this article in WRRO

All publications

Journal articles

Stewart NJ, de Arcos J, Biancardi AM, Collier GJ, Smith LJ, Norquay G, Marshall H, Brau ACS, Lebel RM & Wild JM (2024) Improving Xenon‐129 lung ventilation image SNR with deep‐learning based image reconstruction. Magnetic Resonance in Medicine.
Collier GJ, Smith LJ, Saunders LC, Swift AJ, Marshall H, Stewart NJ, Norquay G, Hughes PJC, Thompson AAR & Wild JM (2024) Age, sex, and lung volume dependence of dissolved xenon‐129 MRI gas exchange metrics. Magnetic Resonance in Medicine. View this article in WRRO
Tahir BA, Hughes PJC, Astley JR, Biancardi AM, Marshall H, Wild JM & Hatton MQ (2024) 1614: MRI V/Q for assessing radiation-induced changes in regional lung function in lung cancer patients. Radiotherapy and Oncology, 194, S5062-S5066.
Astley JR, Biancardi AM, Marshall H, Smith LJ, Hughes PJC, Collier GJ, Saunders LC, Norquay G, Tofan M-M, Hatton MQ , Hughes R et al (2023) PhysVENeT: a physiologically-informed deep learning-based framework for the synthesis of 3D hyperpolarized gas MRI ventilation. Scientific Reports, 13.
Astley JR, Biancardi AM, Marshall H, Hughes PJC, Collier GJ, Hatton MQ, Wild JM & Tahir BA (2023) A hybrid model‐ and deep learning‐based framework for functional lung image synthesis from multi‐inflation CT and hyperpolarized gas MRI. Medical Physics.
Saunders LC, Collier GJ, Chan H-F, Hughes PJC, Smith LJ, Watson J, Meiring J, Gabriel Z, Newman T, Plowright M , Wade P et al (2023) Longitudinal lung function assessment of patients hospitalised with COVID-19 using 1H and 129Xe lung MRI. Chest.
Marshall H, Wild JM, Smith LJ, Hardaker L, Fihn-Wikander T, Müllerová H & Hughes R (2023) Functional imaging in asthma and COPD: design of the NOVELTY ADPro substudy. ERJ Open Research, 9(1).
Marshall H, Voskrebenzev A, Smith LJ, Biancardi AM, Kern AL, Collier GJ, Wielopolski PA, Ciet P, Tiddens HAWM, Vogel‐Claussen J & Wild JM (2022) 129Xe and free-breathing 1H ventilation MRI in patients with cystic fibrosis: a dual-center study. Journal of Magnetic Resonance Imaging.
Chan H-F, Smith LJ, Biancardi AM, Bray J, Marshall H, Hughes PJC, Collier GJ, Rao M, Norquay G, Swift AJ , Hart K et al (2022) Image phenotyping of preterm-born children using hyperpolarised 129Xe lung MRI and multiple-breath washout. American Journal of Respiratory and Critical Care Medicine. View this article in WRRO
Astley JR, Biancardi AM, Hughes PJC, Marshall H, Smith LJ, Collier GJ, Eaden JA, Weatherley ND, Hatton MQ, Wild JM & Tahir BA (2022) Large-scale investigation of deep learning approaches for ventilated lung segmentation using multi-nuclear hyperpolarized gas MRI. Scientific Reports, 12(1).
Singh D, Wild JM, Saralaya D, Lawson R, Marshall H, Goldin J, Brown MS, Kostikas K, Belmore K, Fogel R , Patalano F et al (2022) Effect of indacaterol/glycopyrronium on ventilation and perfusion in COPD: a randomized trial. Respiratory Research, 23(1). View this article in WRRO
Mussell G, Marshall H, Smith L, Biancardi A, Hughes P, Capener D, Bray J, Swift A, Rajaram S, Condliffe A , Collier G et al (2021) Xenon ventilation MRI in difficult asthma; initial experience in a clinical setting. European Respiratory Journal, 7(3). View this article in WRRO
Stewart NJ, Smith LJ, Chan H-F, Eaden JA, Rajaram S, Swift AJ, Weatherley ND, Biancardi A, Collier GJ, Hughes D , Klafkowski G et al (2021) Lung MRI with hyperpolarised gases : current & future clinical perspectives. The British Journal of Radiology, 94. View this article in WRRO
Marshall H, Stewart N, Chan H-F, Rao M, Norquay G & Wild J (2021) In vivo methods and applications of xenon-129 magnetic resonance. Progress in Nuclear Magnetic Resonance Spectroscopy, 122, 42-62. View this article in WRRO
Marshall H, Kenworthy C, Horn F, Thomas S, Swift A, Siddiqui S, Brightling C & Wild J (2020) Peripheral and proximal lung ventilation in asthma; short-term variation and response to bronchodilator. Journal of Allergy and Clinical Immunology. View this article in WRRO
Astley JR, Biancardi AM, Hughes PJC, Smith LJ, Marshall H, Eaden J, Bray J, Weatherley ND, Collier GJ, Wild JM & Tahir BA (2020) 3D Deep Convolutional Neural Network-Based Ventilated Lung Segmentation Using Multi-nuclear Hyperpolarized Gas MRI, 24-35.
Smith LJ, Marshall H, Bray J, Wildman M, West N, Horsley A & Wild JM (2020) The effect of acute maximal exercise on the regional distribution of ventilation using ventilation MRI in CF. Journal of Cystic Fibrosis.
Weatherley ND, Stewart NJ, Chan H-F, Austin M, Smith LJ, Collier G, Rao M, Marshall H, Norquay G, Renshaw SA , Bianchi SM et al (2019) Hyperpolarised xenon magnetic resonance spectroscopy for the longitudinal assessment of changes in gas diffusion in IPF. Thorax, 74(5), 500-502. View this article in WRRO
Tahir BA, Marshall H, Hughes PJC, Brightling CE, Collier G, Ireland RH & Wild JM (2019) Comparison of CT ventilation imaging and hyperpolarised gas MRI: effects of breathing manoeuvre.. Physics in Medicine and Biology. View this article in WRRO
Marshall H, Collier GJ, Johns CS, Chan H, Norquay G, Lawson RA & Wild JM (2019) Imaging Collateral Ventilation in Patients With Advanced Chronic Obstructive Pulmonary Disease: Relative Sensitivity of 3 He and 129 Xe MRI. Journal of Magnetic Resonance Imaging, 49(4), 1195-1197. View this article in WRRO
Tahir BA, Hughes P, Robinson S, Marshall H, Stewart N, Norquay G, Biancardi A, Chan H, Collier GJ, Hart KA , Swinscoe JA et al (2018) Spatial Comparison of CT-Based Surrogates of Lung Ventilation With Hyperpolarized Helium-3 and Xenon-129 Gas MRI in Patients Undergoing Radiation Therapy. International Journal of Radiation Oncology, Biology, Physics, 102(4), 1276-1286. View this article in WRRO
Hughes PJC, Smith L, Chan H-F, Tahir BA, Norquay G, Collier GJ, Biancardi AM, Marshall H & Wild JM (2018) Assessment of the influence of lung inflation state on the quantitative parameters derived from hyperpolarized gas lung ventilation MRI in healthy volunteers.. Journal of Applied Physiology. View this article in WRRO
Smith LJ, Collier GJ, Marshall H, Hughes PJC, Biancardi AM, Wildman M, Aldag I, West N, Horsley A & Wild JM (2018) Patterns of regional lung physiology in cystic fibrosis using ventilation magnetic resonance imaging and multiple-breath washout.. European Respiratory Journal, 52(5). View this article in WRRO
Smith LJ, West N, Hughes D, Marshall H, Johns CS, Stewart NJ, Chan H-F, Rao M, Capener DJ, Bray J , Collier GJ et al (2018) Imaging Lung Function Abnormalities in Primary Ciliary Dyskinesia Using Hyperpolarized Gas Ventilation MRI. Annals of the American Thoracic Society, 15(12), 1487-1490. View this article in WRRO
Stewart NJ, Chan H-F, Hughes PJC, Horn FC, Norquay G, Rao M, Yates DP, Ireland RH, Hatton MQ, Tahir BA , Ford P et al (2018) Comparison of 3 He and 129 Xe MRI for evaluation of lung microstructure and ventilation at 1.5T. Journal of Magnetic Resonance Imaging, 48(3), 632-642. View this article in WRRO
Smith L, Marshall H, Aldag I, Horn F, Collier G, Hughes D, West N, Horsley A, Taylor CJ & Wild J (2018) Longitudinal Assessment of Children with Mild CF Using Hyperpolarised Gas Lung MRI and LCI. American Journal of Respiratory and Critical Care Medicine, 197(3). View this article in WRRO
Horn FC, Marshall H, Collier GJ, Kay R, Siddiqui S, Brightling CE, Parra-Robles J & Wild JM (2017) Regional Ventilation Changes in the Lung: Treatment Response Mapping by Using Hyperpolarized Gas MR Imaging as a Quantitative Biomarker. Radiology, 284(3). View this article in WRRO
Hughes PJC, Horn FC, Collier GJ, Biancardi A, Marshall H & Wild JM (2017) Spatial fuzzy c-means thresholding for semiautomated calculation of percentage lung ventilated volume from hyperpolarized gas and (1) H MRI. Journal of Magnetic Resonance Imaging. View this article in WRRO
Marshall H, Horsley A, Taylor CJ, Smith L, Hughes D, Horn FC, Swift AJ, Parra-Robles J, Hughes PJ, Norquay G , Stewart NJ et al (2017) Detection of early subclinical lung disease in children with cystic fibrosis by lung ventilation imaging with hyperpolarised gas MRI. Thorax, 72(8), 760-762. View this article in WRRO
Coleman R, Collinson M, Bell R, Marshall H, Dodwell D, Keane M, Gil M, Gregory W & Cameron D (2017) Abstract P6-17-01: Adjuvant treatment with zoledronic acid (ZOL) in stage II/III breast cancer. The AZURE trial (BIG 01/04) 10 year follow-up. Cancer Research, 77(4_Supplement).
Stewart NJ, Horn FC, Norquay G, Collier GJ, Yates DP, Lawson R, Marshall H & Wild JM (2016) Reproducibility of quantitative indices of lung function and microstructure from 129Xe chemical shift saturation recovery (CSSR) MR spectroscopy. Magnetic Resonance in Medicine. View this article in WRRO
Spoel M, Marshall H, IJsselstijn H, Parra-Robles J, van der Wiel E, Swift AJ, Rajaram S, Tibboel D, Tiddens HAWM & Wild JM (2016) Pulmonary ventilation and micro-structural findings in congenital diaphragmatic hernia. Pediatric Pulmonology, 51(5), 517-524.
Tahir BA, Van Holsbeke C, Ireland RH, Swift AJ, Horn FC, Marshall H, Kenworthy JC, Parra-Robles J, Hartley R, Kay R , Brightling CE et al (2016) Comparison of CT-based Lobar Ventilation with3He MR Imaging Ventilation Measurements. Radiology, 278(2), 585-592.
Swift AJ, Saunders LC, Sproson T, Hussain N, Collier GJ, Marshall H, Kiely DG & Wild JM (2015) Multiparametric Magnetic Resonance Imaging in Pulmonary Hypertension. Current Cardiovascular Imaging Reports, 8(12).
Collier GJ, Marshall H, Rao M, Stewart NJ, Capener D & Wild JM (2015) Observation of cardiogenic flow oscillations in healthy subjects with hyperpolarized 3 He MRI. Journal of Applied Physiology, 119(9), 1007-1014. View this article in WRRO
Stewart NJ, Leung G, Norquay G, Marshall H, Parra-Robles J, Murphy PS, Schulte RF, Elliot C, Condliffe R, Griffiths PD , Kiely DG et al (2015) Experimental validation of the hyperpolarized 129 Xe chemical shift saturation recovery technique in healthy volunteers and subjects with interstitial lung disease. Magnetic Resonance in Medicine, 74(1), 196-207. View this article in WRRO
Tahir BA, Swift AJ, Marshall H, Parra-Robles J, Hatton MQ, Hartley R, Kay R, Brightling CE, Vos W, Wild JM & Ireland RH (2014) A method for quantitative analysis of regional lung ventilation using deformable image registration of CT and hybrid hyperpolarized gas/ 1 H MRI. Physics in Medicine and Biology, 59(23), 7267-7277. View this article in WRRO
Horn FC, Tahir BA, Stewart NJ, Collier GJ, Norquay G, Leung G, Ireland RH, Parra-Robles J, Marshall H & Wild JM (2014) Lung ventilation volumetry with same-breath acquisition of hyperpolarized gas and proton MRI. NMR in Biomedicine, 27(12), 1461-1467. View this article in WRRO
Marshall H, Kiely DG, Parra-Robles J, Capener D, Deppe MH, van Beek EJR, Swift AJ, Rajaram S, Hurdman J, Condliffe R , Elliot CA et al (2014) Magnetic Resonance Imaging of Ventilation and Perfusion Changes in Response to Pulmonary Endarterectomy in Chronic Thromboembolic Pulmonary Hypertension. American Journal of Respiratory and Critical Care Medicine, 190(5), e18-e19. View this article in WRRO
Swift AJ, Telfer A, Rajaram S, Condliffe R, Marshall H, Capener D, Hurdman J, Elliot C, Kiely DG & Wild JM (2014) Dynamic contrast-enhanced magnetic resonance imaging in patients with pulmonary arterial hypertension.. Pulm Circ, 4(1), 61-70. View this article in WRRO
Horn FC, Deppe MH, Marshall H, Parra-Robles J & Wild JM (2014) Quantification of regional fractional ventilation in human subjects by measurement of hyperpolarized 3He washout with 2D and 3D MRI.. J Appl Physiol (1985), 116(2), 129-139.
Marshall H, Parra-Robles J, Deppe MH, Lipson DA, Lawson R & Wild JM (2014) (3)He pO2 mapping is limited by delayed-ventilation and diffusion in chronic obstructive pulmonary disease.. Magn Reson Med, 71(3), 1172-1178. View this article in WRRO
Janoff S, Marshall H, Leung G, Parra-Robles J, Xu X, Siddiqui S, Brightling C & Wild J (2013) Comparison of lung ventilation volume measurements made with single and separate breath-hold hyperpolarized 3-helium and proton MRI. EUROPEAN RESPIRATORY JOURNAL, 42.
Wild JM, Marshall H, Xu X, Norquay G, Parnell SR, Clemence M, Griffiths PD & Parra-Robles J (2013) Simultaneous imaging of lung structure and function with triple-nuclear hybrid MR imaging.. Radiology, 267(1), 251-255.
Parra-Robles J, Ajraoui S, Marshall H, Deppe MH, Xu X & Wild JM (2012) The influence of field strength on the apparent diffusion coefficient of 3He gas in human lungs.. Magn Reson Med, 67(2), 322-325.
Wild JM, Marshall H, Bock M, Schad LR, Jakob PM, Puderbach M, Molinari F, Van Beek EJR & Biederer J (2012) MRI of the lung (1/3): methods.. Insights Imaging, 3(4), 345-353. View this article in WRRO
Marshall H, Ajraoui S, Deppe MH, Parra-Robles J & Wild JM (2012) K-space filter deconvolution and flip angle self-calibration in 2D radial hyperpolarised ³He lung MRI. NMR in Biomedicine, 25(2), 389-399. View this article in WRRO
Xu X, Norquay G, Parnell SR, Deppe MH, Ajraoui S, Hashoian R, Marshall H, Griffiths PD, Parra-Robles J & Wild JM (2012) Hyperpolarized 129Xe gas lung MRI-SNR and T2* comparisons at 1.5 T and 3 T.. Magn Reson Med, 68(6), 1900-1904.
Marshall H, Deppe MH, Parra-Robles J, Hillis S, Billings CG, Rajaram S, Swift A, Miller SR, Watson JH, Wolber J , Lipson DA et al (2012) Direct visualisation of collateral ventilation in COPD with hyperpolarised gas MRI.. Thorax, 67(7), 613-617. View this article in WRRO
Swift AJ, Rajaram S, Marshall H, Condliffe R, Capener D, Hill C, Davies C, Hurdman J, Elliot CA, Wild JM & Kiely DG (2012) Black blood MRI has diagnostic and prognostic value in the assessment of patients with pulmonary hypertension.. Eur Radiol, 22(3), 695-702.
Ajraoui S, Parra-Robles J, Marshall H, Deppe MH, Clemence M & Wild JM (2012) Acquisition of ³He ventilation images, ADC, T₂* and B₁ maps in a single scan with compressed sensing.. NMR Biomed, 25(1), 44-51.
Deppe MH, Parra-Robles J, Marshall H, Lanz T & Wild JM (2011) A flexible 32-channel receive array combined with a homogeneous transmit coil for human lung imaging with hyperpolarized 3He at 1.5 T.. Magn Reson Med, 66(6), 1788-1797.
Wild JM, Ajraoui S, Deppe MH, Parnell SR, Marshall H, Parra-Robles J & Ireland RH (2011) Synchronous acquisition of hyperpolarised 3He and 1H MR images of the lungs - maximising mutual anatomical and functional information.. NMR Biomed, 24(2), 130-134.
Marshall H, Devine PM, Shanmugaratnam N, Fobel R, Siegler P, Piron CA & Plewes DB (2010) Evaluation of multicoil breast arrays for parallel imaging. Journal of Magnetic Resonance Imaging, 31(2), 328-338.
Marshall H, Hajnal JV, Warren JE, Wise RJ & Larkman DJ (2009) An efficient automated z-shim based method to correct through-slice signal loss in EPI at 3T. Magnetic Resonance Materials in Physics, Biology and Medicine, 22(3), 187-200.
Marshall H, Howarth C, Larkman DJ, Herlihy AH, Oatridge A & Bydder GM (2002) Contrast-Enhanced Magic-Angle MR Imaging of the Achilles Tendon. American Journal of Roentgenology, 179(1), 187-192.
Pilgrim-Morris JH, Smith LJ, Marshall H, Tahir BA, Collier GJ, Stewart NJ & Wild JM () A framework for modelling whole-lung and regional TL_COusing hyperpolarised¹²⁹Xe lung MRI. ERJ Open Research, 00442-2024.
Elbehairy AF, Marshall H, Naish JH, Wild JM, Parraga G, Horsley A & Vestbo J () State of the art review | Advances in COPD imaging using CT and MRI: Linkage with lung physiology and clinical outcomes. European Respiratory Journal, 2301010-2301010.
Moher Alsady T, Voskrebenzev A, Behrendt L, Olsson K, Heußel CP, Gruenig E, Gall H, Ghofrani A, Roller F, Harth S , Marshall H et al () Multicenter Standardization of Phase‐Resolved Functional Lung MRI in Patients With Suspected Chronic Thromboembolic Pulmonary Hypertension. Journal of Magnetic Resonance Imaging.
Astley JR, Biancardi AM, Hughes PJC, Marshall H, Collier GJ, Chan H, Saunders LC, Smith LJ, Brook ML, Thompson R , Rowland‐Jones S et al () Implementable Deep Learning for Multi‐sequence Proton MRI Lung Segmentation: A Multi‐center, Multi‐vendor, and Multi‐disease Study. Journal of Magnetic Resonance Imaging.
Astley JR, Biancardi AM, Marshall H, Hughes PJC, Collier GJ, Smith LJ, Eaden JA, Hughes R, Wild JM & Tahir BA () A Dual‐Channel Deep Learning Approach for Lung Cavity Estimation From Hyperpolarized Gas and Proton MRI. Journal of Magnetic Resonance Imaging.
Behrendt L, Smith LJ, Voskrebenzev A, Klimeš F, Kaireit TF, Pöhler GH, Kern AL, Gonzalez CC, Dittrich A, Marshall H , Schütz K et al () A dual center and dual vendor comparison study of automated perfusion‐weighted phase resolved functional lung (PREFUL) MRI with dynamic contrast enhanced MRI in patients with cystic fibrosis. Pulmonary Circulation.
Smith LJ, Horsley A, Bray J, Hughes PJC, Biancardi A, Norquay G, Wildman M, West N, Marshall H & Wild JM () The assessment of short and long term changes in lung function in CF using 129Xe MRI. European Respiratory Journal, 2000441-2000441.
Weatherley N, Eaden J, Hughes P, Austin M, Smith L, Bray J, Marshall H, Renshaw S, Bianchi S & Wild J () Quantification of pulmonary perfusion in idiopathic pulmonary fibrosis with first pass dynamic contrast enhanced perfusion MRI. Thorax. View this article in WRRO
Saunders LC, Hughes PJC, Alabed S, Capener DJ, Marshall H, Vogel‐Claussen J, Beek EJR, Kiely DG, Swift AJ & Wild JM () Integrated Cardiopulmonary MRI Assessment of Pulmonary Hypertension. Journal of Magnetic Resonance Imaging.

Chapters

Wild JM, Horn FC, Collier GJ & Marshall H (2017) Dynamic Imaging of Lung Ventilation and Gas Flow With Hyperpolarized Gas MRI, Hyperpolarized and Inert Gas MRI (pp. 47-59). Elsevier

Conference proceedings papers

Driskel M, Marshall H, Biancardi A, Smith L, Capener D, Bray J, Zalewska A, Fazal S, Saunders L, Munro R , Rodgers O et al (2024) S2 Evaluation of lung transplant function and detection of CLAD using 129Xe-MRI and LCI. ‘The Catcher in the MRI’ – Functional imaging in lung disease (pp A8-A8)
Saunders L, Collier G, Smith L, Marshall H, Biancardi A, Swift A, Jakymelen D, Strickland S, Gustafsson L, Munro R , Stewart N et al (2024) 129Xe lung ventilation imaging in patients with long COVID without prior respiratory disease. Imaging (pp PA5251-PA5251)
Schofield L, Biancardi A, Smith L, Marshall H, Hughes D, Capener D, Bray J, Fazal S, Zalewska A, Collier G , Norquay G et al (2024) 129Xe-MRI to assess regional airway clearance in children with primary ciliary dyskinesia. Paediatric respiratory physiology and sleep (pp OA4664-OA4664)
Smith L, Marshall H, Jakymelen D, Biancardi A, Collier G, Chan H-F, Hughes P, Brook M, Astley J, Munro R , Rajaram S et al (2024) The sensitivity of different lung function metrics to detect airways disease. Respiratory function technologists/scientists (pp OA4590-OA4590)
Schofield L, Biancardi A, Capener D, Hughes D, Marshall H, Moya E, Robson E, Shanks S, Shawcross A, Singh S , Smith L et al (2024) Can 129Xe ventilation MRI guide personalisation of airway clearance regimens in children with Primary Ciliary Dyskinesia?. Physiotherapists (pp PA1430-PA1430)
Saunders LC, Collier GJ, Smith LJ, Hughes PJC, Marshall H, Chan HF, Biancardi A, Grist J, Strickland S, Gustafsson L , Ho LP et al (2023) S19 Gas exchange imaging using dissolved-phase 129Xe MRI in post COVID cohorts. ‘Shake it off’ – Recovery from COVID-19
Marshall H, Smith LJ, Biancardi A, Collier GJ, Chan HF, Capener D, Bray J, Jakymelen D, Saunders L, Astley J , Tahir BA et al (2023) P177 129Xe MRI phenotyping and longitudinal change in patients with asthma and/or COPD and normal pulmonary function tests. ‘You ain’t seen nothing yet’ – Imaging across COPD, nodules and lung cancer screening
Smith LJ, Marshall H, Biancardi A, Collier GJ, Chan HF, Capener D, Bray J, Jakymelen D, Saunders L, Astley J , Tahir BA et al (2023) P176 Bronchodilator response discordance in patients with asthma and/or COPD assessed by 129Xe-MRI and spirometry. ‘You ain’t seen nothing yet’ – Imaging across COPD, nodules and lung cancer screening
Saunders L, Collier G, Chan H-F, Hughes P, Smith L, Marshall H, Brook M, Biancardi A, Rao M, Norquay G , Stewart N et al (2023) Impaired xenon gas transfer observed two years after COVID-19 hospitalisation in patients with signs of interstitial lung disease. Imaging
Schofield L, Smith L, Biancadi A, Robson E, Marshall H, Capener D, Bray J, Armstrong L, Rodgers J, Munro R , Norquay G et al (2023) Assessing personalised airway clearance techniques in Primary Ciliary Dyskinesia with 129Xe ventilation MRI. Physiotherapists
Smith L, Marshall H, Biancardi A, Collier G, Chan H-F, Capener D, Bray J, Jakymelen D, Saunders L, Astley J , Tahir B et al (2023) Xe-MRI bronchodilator response to assess disease severity in patients with asthma and/or COPD. Respiratory function technologists/scientists
Smith L, Marshall H, Biancardi A, Collier G, Chan H-F, Capener D, Bray J, Jakymelen D, Saunders L, Astley J , Tahir B et al (2023) Bronchodilator response discordance in patients with asthma and/or COPD using Xe-MRI and spirometry. Respiratory function technologists/scientists
Marshall H, Smith L, Biancardi A, Collier G, Chan H-F, Capener D, Bray J, Jakymelen D, Saunders L, Astley J , Tahir B et al (2023) Longitudinal change in lung physiology and 129Xe MRI over 1 year in patients with asthma and/or COPD. Clinical respiratory physiology, exercise and functional imaging
Biancardi A, Marshall H, Smith L, Collier G, Chan H-F, Hughes P, Brook M, Astley J, Munro R, Rajaram S , Swift A et al (2023) Lung physiology and 129Xe MRI data driven clustering of patients with asthma and/or COPD. Clinical respiratory physiology, exercise and functional imaging
Smith L, Marshall H, Jakymelen D, Biancardi A, Collier G, Chan H, Hughes P, Brook M, Astley J, Munro R , Rajaram S et al (2022) 129Xe-MRI and lung function to phenotype ventilation heterogeneity in asthma and/or COPD. 05.02 - Monitoring airway disease
Smith L, Marshall H, Jakymelen D, Biancardi A, Collier GJ, Chan H, Hughes PJC, Brook ML, Astley J, Munro R , Rajaram S et al (2022) Physiological assessment of patients with airways dysanapsis using 129Xe MRI. 09.01 - Respiratory function technologists/scientists
Saunders L, Collier G, Chan H, Hughes P, Smith L, Watson J, Gabriel Z, Meiring J, Plowright M, Newman T , Eaden J et al (2022) Longitudinal lung function assessment of patients hospitalised with COVID-19 using 1H and 129Xe lung MRI. 14.02 - Imaging
Marshall H, Smith LJ, Biancardi A, Collier GJ, Chan HF, Hughes PJC, Brook ML, Astley J, Munro R, Rajaram S , Swift AJ et al (2022) Physiological Phenotypes of Patients with Asthma and/or COPD Using 129Xe MRI. A99. LOOK AT THAT! NEW FINDINGS FROM LUNG IMAGING (pp a2175-a2175)
Marshall H, Smith L, Biancardi A, Collier G, Chan H-F, Hughes P, Astley J, Munro R, Rajaram S, Capener D , Bray J et al (2021) A comparison of 129Xe MRI and advanced lung function testing in patients with asthma and /or COPD: The NOVELTY ADPro substudy. Imaging
Astley J, Biancardi A, Walker M, Hughes P, Marshall H, Collier G, Hatton M, Wild J & Tahir B (2021) Hyperpolarized Gas MRI Ventilation Synthesis From CT: Comparison of Conventional and Deep Learning Methods. MEDICAL PHYSICS, Vol. 48(6)
Astley J, Biancardi A, Hughes P, Smith L, Marshall H, Eaden J, Weatherley N, Collier G, Wild J & Tahir B (2021) Comparison of 3D Deep Convolutional Neural Networks and Training Strategies for Ventilated Lung Segmentation Using Multi-Nuclear Hyperpolarized Gas MRI. MEDICAL PHYSICS, Vol. 48(6)
Wild JM, Biancardi A, Chan H-F, Smith L, Bray J, Marshall H, Collier G, Norquay G, Hughes P, Swift A , Cousins M et al (2019) Imaging functional and microstructural changes in the lungs of children born prematurely. Imaging
Smith L, Hughes D, Chan H-F, Johnson K, Bray J, Rodgers O, Collier G, Norquay G, Biancardi A, Hughes P , Kotecha S et al (2019) 1H and 129Xe MRI to detect functional and structural lung disease in sub-clinical cystic fibrosis. Cystic fibrosis
Austin M, Smith L, Eaden J, Marshall H & Wild J (2019) Validation of nitric oxide transfer factor predicted equations. Respiratory function technologists/scient.
Mussell G, Marshall H, Smith L, Biancardi A, Hughes P, Swift A, Collier G, Wild J & Sabroe I (2019) Correlations of ventilation heterogeneity and spirometry in asthma; initial experience with hyperpolarised gas MRI in a clinical setting. Imaging
Smith L, Collier G, Marshall H, Hughes P, Biancardi A, Norquay G, Bray J, Rodgers O, Wildman M, West N , Horsley A et al (2019) Clinical applicability of 3He and 129Xe ventilation MRI in cystic fibrosis: longitudinal follow up. Cystic fibrosis
Smith L, Hughes D, Chan H-F, Johnson K, Bray J, Rodgers O, Collier G, Norquay G, Biancardi A, Hughes P , Kotecha S et al (2019) WS17-2 The sensitivity of MRI to detect both functional and structural lung abnormalities in sub-clinical cystic fibrosis. Journal of Cystic Fibrosis, Vol. 18 (pp S32-S32)
Smith L, Collier G, Marshall H, Hughes P, Biancardi A, Norquay G, Bray J, Rodgers O, Wildman M, West N , Horsley A et al (2019) P213 A comparison of ventilation MRI using hyperpolarised 3He and 129Xe to assess cystic fibrosis lung disease. Journal of Cystic Fibrosis, Vol. 18 (pp S117-S117)
Smith L, Marshall H, Norquay G, Collier G, Rodgers O, Hughes P, Biancardi A, West N, Wildman M, Horsley A & Wild J (2019) P211 129Xe ventilation MRI and LCI to assess acute maximal exercise as a method of airway clearance. Journal of Cystic Fibrosis, Vol. 18 (pp S116-S117)
Smith L, Collier G, Marshall H, Hughes P, Biancardi A, Norquay G, Bray J, Rodgers O, Wildman M, West N , Horsley A et al (2019) P212 Ventilation MRI tracks longitudinal lung function changes in patients with cystic fibrosis and clinically stable FEV1 and Lung Clearance Index. Journal of Cystic Fibrosis, Vol. 18 (pp S117-S117)
Hart K, Marshall H, Swinscoe J, Robinson S, Matthew T, Tozer-Loft S, Hatton M, Wild J, Ireland R & Tahir B (2019) OC-0523 3He MRI for functional lung avoidance VMAT treatment planning in lung cancer. Radiotherapy and Oncology, Vol. 133 (pp S274-S275) View this article in WRRO
Weatherley ND, Stewart NJ, Chan HF, Hughes PJC, Marshall H, Austin M, Smith L, Collier G, Rao M, Norquay G , Renshaw SA et al (2018) Probing diffusion and perfusion in idiopathic pulmonary fibrosis with hyperpolarised xenon and dynamic contrast-enhanced magnetic resonance imaging. Thorax, Vol. 73(Suppl 4) (pp A44-A45). London, UK, 5 December 2018 - 7 December 2018. View this article in WRRO
Marshall H, Voskrebenzev A, Biancardi A, Smith L, Tahir B, Wild J & Vogel-Claussen J (2018) Comparison of 1H MRI and 3He MRI ventilation images in patients with cystic fibrosis and patients with lung cancer. Imaging
Smith L, Collier G, Marshall H, Hughes P, Bray J, Rodgers O, Aldag I, West N, Wildman M, Horsley A & Wild J (2018) The effect of inhaled lung volume on ventilation heterogeneity in CF using 3He MRI. Cystic fibrosis
Tahir B, Hughes P, Robinson S, Marshall H, Stewart N, Biancardi A, Chan HF, Collier G, Hart K, Swinscoe J , Hatton M et al (2018) OC-0182: A comparison of CT ventilation with 3He and 129Xe MRI for functional avoidance treatment planning. Radiotherapy and Oncology, Vol. 127(Supplement 1) (pp S96-S97). Barcelona, Spain, 20 April 2018 - 24 April 2018. View this article in WRRO
Smith L, Hughes PJ, Marshall H, Collier G, West N, Wildman M, Horsley A & Wild JM (2018) Hyperpolarised Gas MRI Shows Reversibility of Lung Ventilation Defects at Increased Inspiratory Lung Volumes in Cystic Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
Weatherley N, Marshall H, Hughes P, Austin M, Smith L, Renshaw SA, Bianchi S & Wild JM (2018) Dynamic Contrast-Enhanced Magnetic Resonance Imaging for the Evaluation of Perfusion Heterogeneity in Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
Johns C, Marshall H, Swift AJ, Jagan R, Nicholas WD, Laurie S, Chan H, Wild JM & Lawson RA (2018) Assessment of Suitable Patients and Targets for Lung Volume Reduction with Endobronchial Valves in COPD. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
West N, Smith L, Chan H-F, Horn F, Chetcuti P, Moya E, Marshall H, Wild J, Norquay G, Collier G & Rao M (2017) Hyperpolarised gas ventilation MRI detects early lung ventilation heterogeneity in children with primary ciliary dyskinesia. Paediatric Respiratory Physiology and Sleep
Weatherley N, Chan H-F, Stewart N, Norquay G, Rao M, Collier G, Austin M, Smith L, Marshall H, Renshaw SA , Bianchi S et al (2017) Late breaking abstract - Hyperpolarised gas MRI demonstrates sub-clinical progression in IPF over 6 months. European Respiratory Journal, Vol. 50(Suppl 61). Milan, Italy, 9 September 2017 - 13 September 2017. View this article in WRRO
Hughes P, Smith L, Horn F, Biancardi A, Collier G, Stewart N, Norquay G, Rao M, Aldag I, Taylor C , Marshall H et al (2017) Ventilation heterogeneity assessed in patients with mild cystic fibrosis and asthma using Hyperpolarised gas MRI histogram analysis. Imaging
Chan H-F, Collier G, Smith L, Marshall H, Hughes P, Parra-Robles J, Horn F, Norquay G, Stewart N, Taylor C , Aldag I et al (2017) Longitudinal monitoring of lung microstructure with HP gas diffusion-weighted MRI in mild cystic fibrosis children. Cystic Fibrosis View this article in WRRO
Tahir B, Hughes P, Marshall H, Hart K, Swinscoe J, Wild J, Ireland R & Hatton M (2017) P2.05-032 CT-Based Surrogates of Pulmonary Ventilation in Lung Cancer: A Voxel-Level Comparison with HP Gas MRI. Journal of Thoracic Oncology, Vol. 12(1) (pp S1050-S1050)
Smith L, Aldag I, Hughes P, Horn F, Marshall H, Norquay G, Collier G, West N, Hughes D, Taylor C , Horsley AR et al (2016) LONGITUDINAL MONITORING OF DISEASE PROGRESSION IN CHILDREN WITH MILD CF USING 3-HELIUM MRI AND LCI. Pediatric Pulmonology, Vol. 51 (pp 348-348) View this article in WRRO
Stewart N, Chan H-F, Hughes P, Collier G, Horn F, Norquay G, Parra-Robles J, Yates D, Collini P, Lawson R , Marshall H et al (2016) Comparison of 3 He and 129 Xe MRI for evaluation of lung microstructure and ventilation at 1.5 T. European Respiratory Journal, Vol. 48(suppl 60), 3 September 2016 - 7 September 2016. View this article in WRRO
Smith L, Horn F, Marshall H, Collier G, Hughes P, Aldag I, Taylor C, Horsley A & Wild J (2016) Comparison of phase III slope analysis from MBW with hyperpolarised gas MRI in children with mild CF. 9.1 Respiratory Function Technologists/Scientists
Smith L, Aldag I, Hughes P, Horn F, Marshall H, Norquay G, Collier G, Hughes D, Taylor C, Horsley A & Wild J (2016) Longitudinal monitoring of disease progression in children with mild CF using hyperpolarised gas MRI and LCI. 9.1 Respiratory Function Technologists/Scientists View this article in WRRO
Tahir B, Marshall H, Hughes P, Stewart N, Horn F, Collier G, Norquay G, Hart K, Swinscoe J, Hatton M , Wild J et al (2016) Ventilation CT : voxel-level comparison with HP gas MRI. European Respiratory Journal, Vol. 48(Suppl 60). Estoril, Portugal, 10 March 2016 - 13 March 2016. View this article in WRRO
Tahir B, Marshall H, Hughes P, Stewart N, Horn F, Collier G, Norquay G, Hart K, Swinscoe J, Hatton M , Wild J et al (2016) WE-AB-202-07: Ventilation CT: Voxel-Level Comparison with Hyperpolarized Helium-3 & Xenon-129 MRI. Medical Physics, Vol. 43(6) (pp 3795-3796), 31 July 2016 - 4 August 2016. View this article in WRRO
Aldag I, Marshall H, Taylor C, Horsley A, Hughes D, Smith L, Horn F, Swift A, Parra-Robles J, Hughes P , Collier G et al (2016) WS15.2 Multiple breath washout and imaging with 3 He MRI and CT scans to monitor early-stage lung disease in patients with cystic fibrosis. Journal of Cystic Fibrosis, Vol. 15 (pp S24-S25)
Zaidi S, Wild JM, Swift A, Marshall H, Weateherley N, Horn FC, Niven RM & Ryan D (2015) P285 Helium Magnetic Resonance Imaging Identifies Regional Ventilation, Perfusion and Microstructure Abnormalities in a Case of “Horse-shoe” Lung. Thorax, Vol. 70(Suppl 3) (pp A222-A223)
Weatherley ND, Stewart NJ, Marshall H, Collier G, Hart K, Horn F, Norquay G, Whyte MK, Bianchi S & Wild JM (2015) P286 Correlations of functional multi-nuclear MR imaging indices with pulmonary function tests in the assessment of idiopathic pulmonary fibrosis. Thorax, Vol. 70(Suppl 3) (pp A223.1-A223)
Wild JM, Collier G, Marshall H, Smith L, Norquay G, Swift AJ, Horn FC, Chan F, Stewart NJ, Hutchison LC , Rao M et al (2015) P283 Hyperpolarised Gas MRI – a pathway to Clinical Diagnostic Imaging. Thorax, Vol. 70(Suppl 3) (pp A220.3-A221)
Horn F, Rao M, Stewart N, Marshall H, Parra-Robles J & Wild J (2015) Multi nuclear 3D multiple breath washout imaging with hyperpolarised3He and129Xe MRI. 1.3 Imaging
Stewart NJ, Marshall H & Wild JM (2015) Repeatability of129Xe MR methods for quantification of interstitial thickness. 4.1 Clinical respiratory physiology, exercise and functional imaging
Horn F, Marshall H, Siddiqui S, Horsley A, Smith L, Aldag I, Brightling C, Kay R, Taylor C, Parra-Robles J & Wild J (2015) Comparison of ventilation heterogeneity (VH) measured with multiple breath washout (MBW) imaging to whole lung MBW LCI and FEV1in asthma and cystic fibrosis (CF). 4.1 Clinical respiratory physiology, exercise and functional imaging
Wild J, Smith L, Horn F, Collier G, Swift A, Stewart N, Rao M, Norquay G, Hughes D, Ugonna K & Marshall H (2015) Hyperpolarised gas MR lung imaging – Breaks through to clinical practice. 1.3 Imaging
Smith L, Horn F, Marshall H, Aldag I, Taylor C, Wild J & Horsley A (2015) Effect of posture on lung clearance index (LCI) and lung volumes in children with early stage cystic fibrosis lung disease. 9.1 Respiratory Function Technologists/Scientists
Stewart NJ, Norquay G, Parra-Robles J, Marshall H, Leung G, Murphy PS, Schulte RF, Elliot CA, Condliffe R, Billings CG , Smith I et al (2015) Assessment of lung microstructure in ILD with3He and129Xe MRI. 4.1 Clinical respiratory physiology, exercise and functional imaging
Stewart N, Norquay G, Parra-Robles J, Marshall H, Leung G, Murphy P, Schulte R, Elliot C, Condliffe R, Billings C , Smith I et al (2014) P273 Assessment Of Lung Microstructure In Interstitial Lung Disease With Hyperpolarised Gas Mri. Thorax, Vol. 69(Suppl 2) (pp A192-A193)
Horn F, Horsley A, Smith L, Taylor C, Marshall H, Parra-Robles J & Wild J (2014) Visualising regional ventilation heterogeneity by linking multiple breath washout to He-3 MRI imaging. EUROPEAN RESPIRATORY JOURNAL, Vol. 44
Hart K, Marshall H, Stewart N, Whyte M & Wild J (2014) Quantitative lung T-1 mapping and oxygen enhanced MRI in IPF. EUROPEAN RESPIRATORY JOURNAL, Vol. 44
Horn F, Marshall H, Parra-Robles J, Brightling C & Wild J (2014) Delayed gas filling imaged in asthma patients using hyperpolarised He-3 MRI. EUROPEAN RESPIRATORY JOURNAL, Vol. 44
Stewart NJ, Leung G, Norquay G, Marshall H, Parra-Robles J, Billings C, Murphy P, Schulte RF, Wolber J, Kiely DG , Whyte MKB et al (2014) Age-dependent changes in whole-lung septal thickness measured by Xe-129 MRI: A comparison of healthy volunteers and subjects with IPF. EUROPEAN RESPIRATORY JOURNAL, Vol. 44
Marshall H, Hughes D, Horsley A, Horn F, Smith L, Parra-Robles J, Cunningham S, Armstrong L, Aldag I, Taylor C & Wild J (2014) Detection of early-stage lung disease in cystic fibrosis; comparing the sensitivity of He-3 and H-1 MRI, CT and LCI. EUROPEAN RESPIRATORY JOURNAL, Vol. 44
Stewart NJ, Norquay G, Marshall H & Wild JM (2014) Feasibility of high quality lung MRI with naturally abundant hyperpolarised Xe-129. EUROPEAN RESPIRATORY JOURNAL, Vol. 44
Stewart NJ, Leung G, Norquay G, Marshall H, Parra-Robles J, Billings C, Murphy P, Schulte RF, Wolber J, Kiely DG , Whyte MKB et al (2014) Age-dependent changes in whole-lung septal thickness measured by Xe-129 MRI: A comparison of healthy volunteers and subjects with IPF. EUROPEAN RESPIRATORY JOURNAL, Vol. 44
Horsley A, Marshall H, Smith L, Hughes D, Horn F, Armstrong L, Parra-Nobles J, Cunningham S, Aldag I, Wild J & Taylor C (2014) WS13.5 Visualising ventilation heterogeneity in mild CF using hyperpolarised 3He MRI, and comparison with lung clearance index (LCI). Journal of Cystic Fibrosis, Vol. 13 (pp S28-S28)
Horn F, Horsley A, Marshall H, Taylor C, Parra-Robles J & Wild JM (2014) Linking Helium-3 Mri Washout Imaging To Multiple Breath Washout - First Steps To Understanding Regional Lung Ventilation Heterogeneity. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 189
Stewart NJ, Leung G, Norquay G, Marshall H, Parra-Robles J, Wolber J, Schulte RF, Condliffe R, Elliot C, Murphy P , Kiely D et al (2014) Dissolved 129xe Mri - Delayed Gas Uptake Indicates Septal Thickening In Patients With Idiopathic Pulmonary Fibrosis And Systemic Sclerosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 189
Horn F, Marshall H, Barber D, Kay R, Siddiqui S, Brightling C, Parra-Robles J & Wild JM (2014) Quantitative Mapping Of Treatment Response In The Lungs Of Asthmatics Using Hyperpolarized Ventilation Helium-3 Mri. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 189
Kenworthy JC, Marshall H, Parra-Robles J, Leung G, Xu X, Siddiqui S, Kay R, Brightling C & Wild JM (2014) Reproducibility Of Lung Ventilation Volume From Helium-3 And Proton Mri In Asthmatics. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 189
Marshall H, Hughes D, Horsley A, Horn F, Smith L, Parra-Robles J, Armstrong L, Aldag I, Taylor C & Wild JM (2014) Assessment Of Structural And Functional Changes In Early Stage Cf With Helium-3 Mri, CT And Multi-Breath Washout. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 189
Marshall H, Thomas S, Parra-Robles J, Siddiqui S, Kay R, Brightling C & Wild JM (2014) Mutli-Nuclear Mr Imaging Of Vq Distribution Response To Bronchodilator In Asthma. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 189
Parra-Robles J, Marshall H, Lawson R & Wild JM (2014) Mapping The Microscopic Distribution Of Acinar Airway Length Scales Using Fractal Exponential Analysis Of Helium-3 Diffusion Mri. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 189
Marshall H, Horsley A, Smith L, Hughes D, Horn F, Armstrong L, Parra-Robles J, Cunningham S, Aldag I, Taylor C & Wild JM (2013) HYPERPOLARISED 3HE MRI IS SUPERIOR TO LUNG CLEARANCE INDEX IN DETECTION OF VENTILATION ABNORMALITIES IN YOUNG CHILDREN WITH MILD CF. THORAX, Vol. 68 (pp A7-A8)
Horn F, Marshall H, Barber D, Parra-Robles J, Lipson D, Lawson R & Wild J (2013) Bronchodilator treatment response mapping in COPD using hyperpolarised gas ventilation MRI. EUROPEAN RESPIRATORY JOURNAL, Vol. 42
Kenworthy J, Marshall H, Thomas S, Parra-Robles J, Xu X, Leung G, Siddiqui S, Brightling C & Wild JM (2013) Quantifying peripheral and central lung response to bronchodilator in asthma with hyperpolarised gas MRI. EUROPEAN RESPIRATORY JOURNAL, Vol. 42
Marshall H, Janoff S, Parra-Robles J, Miller S, Harrison S, Deppe M, Lipson D, Lawson R & Wild J (2013) Imaging of bronchodilator effects in COPD with hyperpolarised He-3 and H-1 MRI. EUROPEAN RESPIRATORY JOURNAL, Vol. 42
Spoel M, Marshall H, IJsselstijn H, Parra-Robles J, Wielopolski P, van der Wiel E, Swift A, Rajaram S, Tibboel D, Tiddens HA & Wild JM (2013) (HE)-H-3 MRI IN YOUNG ADULTS WITH CONGENITAL DIAPHRAGMATIC HERNIA: ALVEOLAR SIZE DIFFERENCES BETWEEN THE IPSI- AND CONTRALATERAL LUNG. INTENSIVE CARE MEDICINE, Vol. 39 (pp S107-S107)
Marshall H, Siddiqui S, Leung G, Parra-Robles J, Xu X, Brightling C & Wild J (2013) Imaging The Effect Of Airway Opening In Asthma Due To Inflation State With 3he Mri. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 187
Parra-Robles J, Marshall H & Wild JM (2012) Modelling of hyperpolarized gas diffusion in lungs of COPD patients and healthy volunteers using a fractional dynamics approach. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
Spoel M, Marshall H, IJsselstijn H, Parra-Robles J, Wielopolski P, van der Wiel E, Swift A, Rajaram S, Tibboel D, Tiddens H & Wild J (2012) He-3 MRI in young adults with congenital diaphragmatic hernia: Alveolar size differences between lungs. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
Marshall H, Deppe M, Parra-Robles J, Lipson D, Lawson R & Wild J (2012) MRI of delayed-ventilation perfusion matching in COPD. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
Janoff S, Marshall H, Deppe M, Billings C, Parra-Robles J, Hillis S, Miller S, Lipson D, Wild J & Lawson R (2012) Quantifying lung function in COPD with hyperpolarised He-3 MRI. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
Wild J, Marshall H, Xu X, Norquay G & Parra-Robles J (2012) Simultaneous imaging of lung structure and function with triple nuclear MRI. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
Wild JM, Marshall H, Norquay G, Xu P & Parra-Robles J (2012) Simultaneous imaging of lung structure and function with triple nuclear MRI. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
Marshall H, Deppe MH, Parra-Robles J, Hillis S, Billings C, Rajaram S, Swift AJ, Miller SR, Watson JH, Wolber J , Lipson DA et al (2012) Direct Imaging Of Delayed And Collateral Ventilation In COPD Using Hyperpolarised Gas MRI. D100. THE BIG ROLE OF SMALL AIRWAYS
Marshall H, Kiely DG, Capener D, Deppe MH, Parra-Robles J, Swift AJ, Rajaram S, Hurdman J, Condliffe R, Wild JM & Elliot CA (2012) Imaging V/Q In Chronic Thromboembolic Pulmonary Hypertension With 3He And 1H MRI. B98. NOVEL APPROACHES TO LUNG IMAGING
Rajaram S, Swift A, Marshall H, Capener D, Condliffe R, Hurdman J, Elliot C, Wild JM & Kiely DG (2012) Evaluation Of MR Lung Perfusion In The Assessment Of Chronic Thromboembolic Pulmonary Hypertension. C28. DIAGNOSIS AND TREATMENT OF PULMONARY HYPERTENSION
Marshall H, Deppe MH, Parra-Robles J, Hillis S, Billings C, Miller SR, Watson JH, Wolber J, Lipson DA, Lawson R & Wild JM (2011) DIRECT VISUALISATION OF COLLATERAL VENTILATION IN COPD WITH HYPERPOLARISED GAS MRI. THORAX, Vol. 66 (pp A54-A55)
Hatton M, Ireland RH, Swincoe JA, Marshall H, Ajraoui S, Parra-Roubles J & Wild J (2011) AUTOMATIC IMAGE REGISTRATION OF LUNG CT WITH SYNCHRONOUSLY ACQUIRED HYPERPOLARIZED HELIUM-3 MRI AND PROTON MRI FOR PATIENTS WITH NSCLC. J THORAC ONCOL, Vol. 6(6) (pp S1123-S1124)
Ireland R, Swinscoe J, Hatton M, Marshall H, Ajraoui S, Parra-Robles J & Wild J (2011) 1290 poster IMAGE REGISTRATION OF LUNG CT AND HYPERPOLARIZED HELIUM-3 MRI VIA PROTON MRI FOR PATIENTS WITH NSCLC. Radiotherapy and Oncology, Vol. 99 (pp S481-S482)
Saunders L, Collier G, Smith L, Marshall H, Biancardi A, Jakymelen D, Strickland S, Gustafsson L, Munro R, Rodgers O , Stewart N et al () 129Xe lung ventilation imaging in patients with long COVID without prior respiratory disease. ISMRM Annual Meeting, 4 May 2024 - 9 May 2024.
Pilgrim-Morris J, Collier G, Munro R, Marshall H, Norquay G, Stewart N & Wild J () Compressed sensing reconstruction for high-SNR, rapid dissolved 129Xe gas exchange MRI. ISMRM Annual Meeting, 4 May 2024 - 9 May 2024.
Saunders L, Collier G, Chan H-F, Hughes P, Smith L, Stewart N, Brooke J, Watson J, Meiring J, Gabriel Z , Newman T et al () Impaired xenon gas transfer observed one year after hospitalisation due to COVID-19 in patients with signs of interstitial lung disease.. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
Pilgrim-Morris J, Smith L, Astley J, Saunders L, Collier G, Biancardi A, Tahir B, Marshall H, Hardaker L, Fihn-Wikander T , Hughes R et al () Modelling Whole-Lung and Regional Carbon Monoxide Transfer Factor with Hyperpolarized 129Xe MRI in Asthma and COPD Patients. ISMRM Annual Meeting, 3 July 2023 - 8 July 2023.
Marshall H, Collier G, Smith L, Chan H-F, Hughes P, Capener D, Bray J, Joseph S, Munro R, Rodgers O , Ball J et al () 129Xe gas transfer lung MRI before and after bronchodilator inhalation in patients with asthma and/or COPD. ISMRM Annual Meeting, 3 July 2023 - 8 July 2023.
Marshall H, Collier G, Chan H-F, Smith L, Hughes P, Capener D, Bray J, Joseph S, Munro R, Rodgers O , Ball J et al () Longitudinal 129Xe MRI assessment of lung gas transfer and microstructure over 1 year in patients with asthma and/or COPD. ISMRM Annual Meeting, 3 July 2023 - 8 July 2023.
Stewart N, de Arcos J, Biancardi A, Pilgrim-Morris J, Rodgers O, Munro R, Collier G, Norquay G, Marshall H, Brau A , Lebel M et al () Improving Xenon-129 Lung Ventilation Image Quality with a Commercial Deep-Learning Based Image Reconstruction. ISMRM Annual Meeting, 3 July 2023 - 8 July 2023.
Hughes P, Marshall H, Smith L, Jakymelen D, Biancardi A, Collier G, Chan H-F, Brook M, Astley J, Munro R , Rajaram S et al () Differentiating patients with asthma and/or chronic obstructive pulmonary disease using lung T1 and M0. ISMRM Annual Meeting, 3 July 2023 - 8 July 2023.
Collier G, Chan H-F, Stewart N, Norquay G, Smith L, Rao M, Marshall H, Schulte R & Wild J () Age and lung volume dependence of dissolved xenon-129 imaging parameters. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
Chan H-F, Collier G, Smith L, Biancardi A, Bray J, Marshall H, Hughes P, Rao M, Norquay G, Swift A , Hart K et al () Dissolved 129Xe spectroscopy in the lungs of preterm-born children. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
Tahir B, Hughes P, Atkinson J, Jadav I, Astley J, Robinson S, Biancardi A, Marshall H, Hart K, Swinscoe J , Ireland R et al () Multi-modal assessment of dose-related changes in regional lung function in non-small cell lung cancer patients receiving radiotherapy. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
Astley J, Biancardi A, Marshall H, Tofan M-M, Smith L, Hughes P, Collier G, Hatton M, Blé F-X, Hughes R , Wild J et al () Deep learning-based synthesis of hyperpolarized gas MRI ventilation from 3D multi-inflation proton MRI. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
Astley J, Biancardi A, Marshall H, Hughes P, Collier G, Smith L, Eaden J, Blé F-X, Hughes R, Wild J & Tahir B () A multi-channel deep learning approach for lung cavity estimation from hyperpolarized gas and proton MRI. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
Marshall H, Smith L, Biancardi A, Collier G, Chan H-F, Hughes P, Brook M, Astley J, Munro R, Rajaram S , Swift A et al () 129Xe MRI patterns of lung function in patients with asthma and/or COPD in the NOVELTY study. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
Saunders L, Collier G, Chan H-F, Hughes P, Smith L, Marshall H, Eaden J, Bray J, Capener D, Armstrong L , Rodgers J et al () Multinuclear lung MRI assessment of COVID-19 patients at 6 and 12 weeks after hospital admission. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.

Other

Rajaram S, Swift AJ, Telfer A, Hurdman J, Marshall H, Lorenz E, Capener D, Davies C, Hill C, Elliot C , Condliffe R et al (2013) 3D contrast-enhanced lung perfusion MRI is an effective screening tool for chronic thromboembolic pulmonary hypertension: results from the ASPIRE Registry.. Thorax, 68(7), 677-678.
Marshall H, Wild JM & Lawson R (2012) Authors' response to assessment of intraparenchymal lung collateral ventilation. Thorax.

Preprints

Saunders LC, Collier GJ, Chan H-F, Hughes PJC, Smith LJ, Watson J, Meiring J, Gabriel Z, Newman T, Plowright M , Eaden JA et al () Longitudinal lung function assessment of patients hospitalised with COVID-19 using ¹H and ¹²⁹Xe lung MRI, Cold Spring Harbor Laboratory.

Current projects

Imaging a large cohort of patients with asthma and/or COPD with ¹²⁹Xe MRI as a sub-study of the NOVELTY study.
Comparison of hyperpolarised gas and free-breathing proton ventilation MRI in patients with cystic fibrosis.
Imaging the effects of mepolizumab in patients with COPD.