Dr Sarbendra Pradhananga

Clinical Medicine, School of Medicine and Population Health

Postdoctoral Research Associate

S.L.Pradhananga@sheffield.ac.uk

The Medical School

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Dr Sarbendra Pradhananga
Clinical Medicine, School of Medicine and Population Health
The Medical School
Beech Hill Road
Sheffield
S10 2RX

Publications

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Journal articles

Wilkinson IR, Pradhananga SL, Speak R, Artymiuk PJ, Sayers JR & Ross RJ (2016) A long-acting GH receptor antagonist through fusion to GH binding protein.. Scientific Reports, 6. View this article in WRRO
Wilkinson I, Pradhananga S, Sayers J, Artymiuk P, Phipps M & Ross R (2014) OR5-3: A GH antagonist fusion with GH binding protein is biologically active, shows delayed clearance and inhibits growth in a rabbit model. Growth Hormone & IGF Research, 24, S14-S15.
Pradhananga SL, Wilkinson IR, Ferrandis E, Artymiuk PJ, Sayers JR & Ross RJ (2013) Ligand-Receptor Fusion Dimers, 227-235.
Bielohuby M, Pradhananga S, Wilkinson IR, Sayers JR, Artymiuk PJ, Ross RJM & Bidlingmaier M (2012) P02-27 Challenges encountered in the development of an in vivo mouse model system for testing growth hormone antagonist molecules. Growth Hormone & IGF Research, 22, S63-S63.
Wilkinson IR, Bielohuby M, Parry H, Thorpe A, Pradhananga S, Sayers JR, Artymiuk PJ, Bidlingmaier M & Ross RJ (2012) OR03-1 Development of a platform technology to generate long-acting protein therapeutics. Growth Hormone & IGF Research, 22, S6-S7.
Pradhananga S & Sayers JR (2012) Biologics, biosimilars and biobetters in protein hormone therapy: Natural synthesis. Biochemist, 34(1), 10-15.
Ferrandis E, Pradhananga SL, Touvay C, Kinoshita C, Wilkinson IR, Stafford K, Wu Z, Strasburger CJ, Sayers JR, Artymiuk PJ & Ross RJ (2010) Immunogenicity, toxicology, pharmacokinetics and pharmacodynamics of growth hormone ligand-receptor fusions.. Clin Sci (Lond), 119(11), 483-491.
Wilkinson IR, Ferrandis E, Artymiuk PJ, Teillot M, Soulard C, Touvay C, Pradhananga SL, Justice S, Wu Z, Leung KC , Strasburger CJ et al (2007) A ligand-receptor fusion of growth hormone forms a dimer and is a potent long-acting agonist.. Nat Med, 13(9), 1108-1113.
Pradhananga S, Wilkinson I & Ross RJ (2002) Pegvisomant: structure and function. Journal of Molecular Endocrinology, 29(1), 11-14.
Pradhananga SL, Rowling PJ, Simpson IN & Payne DJ (1996) Sensitivity of L-2 type beta-lactamases from Stenotrophomonas maltophilia to serine active site beta-lactamase inhibitors.. J Antimicrob Chemother, 37(2), 394-396.

Chapters

Thorpe A, Freeman H, Pradhananga SL, Wilkinson IR & Ross RJM (2011) Long-Acting Growth Hormone Analogues, Growth Hormone Related Diseases and Therapy (pp. 361-373). Humana Press

Conference proceedings papers

Ferrandis E, Pradhananga SL, Touvay C, Kinoshita C, Wilkinson IR, Stafford K, Wu Z, Strasburger CJ, Sayers JR, Artymiuk PJ & Ross RJ (2010) Immunogenicity, Toxicology, Pharmacokinetics and Pharmacodynamics of Growth Hormone Ligand-Receptor Fusions.. ENDOCRINE REVIEWS, Vol. 31(3)