Hearing and balance hero image


Ceriani F, Hendry A, Jeng JY, Johnson S, Olt J, Holley MC, Mammano F, Kros CJ, Simmons DD, Marcotti W (2019) Coordinated Ca2+ activity of cochlear sensory and non-sensory cells refines OHC afferent innervation”. EMBO J, e99839.

Johnson SL, Safieddine S, Mustapha M, Marcotti W (2019) Hair Cell Afferent Synapses: Function and Dysfunction. Cold Spring Harb Perspect Med. pii: a033175.

Groot SC, Sliedregt K, Benthem PPG, Rivolta MN, Huisman MA (2019) Building an Artificial Stem Cell Niche: Prerequisites for Future 3D‐Formation of Inner Ear Structures ‐ Towards 3D Inner Ear Biotechnology –. The Anatomical Record.

Abbas L & Rivolta MN (2019) The use of animal models to study cell transplantation in neuropathic hearing loss. Hear Res. 377, 72-87

Smeriglio P, Leu R and Mustapha M (2019) TSP1 and TSP2 have unique and overlapping roles in protecting against noise-induced auditory synaptopathy. Neuroscience;408:68-80.


Corns LF, Johnson S, Roberts T, Ranatunga K, Hendry A, Ceriani F, Safieddine S, Steel K, Forge A, Petit C, Furness D, Kros C, Marcotti W (2018) Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation. Nature Comm, 9:4015.

Chessum et al (17 authors) Marcotti W, Brown SDM, Elkon R, Bowl MR, Hertzano R (2018) Ikzf2/helios is a key transcriptional regulator of outer hair cell maturation. Nature, 563:696-700.

Razlivanov I, Liew T, Moore EW, Al-Kathiri A, Bartram T, Kuvshinov D & Nikolaev A (2018) Long-term imaging of calcium dynamics using genetically encoded calcium indicators and automatic tracking of cultured cells. BioTechniques, 65, 37-39.

Bergmann K, Meza Santoscoy P, Lygdas K, Nikolaeva Y, MacDonald R, Cunliffe V & Nikolaev A (2018) Imaging Neuronal Activity in the Optic Tectum of Late Stage Larval Zebrafish. J Dev Biol, 6(1).

Iannitti T, Scarrott J, Likhite S, Coldicott IRP, Lewis KE, Heath PR, Higginbottom A, Myszczynska MA, Milo M, Hautbergue GM, Meyer K et al (2018) Translating SOD1 Gene Silencing toward the Clinic: A Highly Efficacious, Off-Target-free, and Biomarker-Supported Strategy for fALS. Mol Ther: Nucleic Acids, 12, 75-88.

García-Alcántara F, Murillo-Costa S, Pulido S, Bermúdez-Muñoz JM, Martínez-Vega R, Milo M, Varela-Nieto I, Rivera T (2018) The expression of oxidative stress response genes is modulated by a combination of resveratrol and N-acetylcysteine to ameliorate ototoxicity in the rat cochlea. Hear Res, 358, 10-21.

Stacey G, Andrews P, Asante C, Barbaric I, Barry J, Bisset L, Braybrook J, Buckle R, Chandra A, Coffey P , Crouch S et al (2018) Science-based assessment of source materials for cell-based medicines: report of a stakeholders workshop. Reg Med 13, 935-944.


Johnson SL, Olt J, Cho S, von Gersdorff H, Marcotti W (2017) The coupling between Ca2+ channels and the exocytotic Ca2+ sensor at hair cell ribbon synapses varies tonotopically along the mature cochlea. J Neurosci. 37:258-268.

Johnson SL, Ceriani F, Houston O, Polishchuk R, Polishchuk E, Crispino G, Zorzi V, Mammano F, Marcotti W (2017) Connexin-Mediated Signaling in Nonsensory Cells Is Crucial for the Development of Sensory Inner Hair Cells in the Mouse Cochlea. J Neurosci 37: 258-268.

Corns LF, Jeng JY, Richardson GP, Kros CJ, Marcotti W (2017) TMC2 modifies permeation properties of the mechanoelectrical transducer channel in early postnatal mouse cochlear outer hair cells. Front Mol Neurosci. 10:326.

Erickson T, Morgan CP, Olt J, Hardy K, Busch-Nentwich E, Maeda R, Clemens R, Krey JF, Nechiporuk A, Barr-Gillespie PG, Marcotti W, Nicolson T (2017) Integration of Tmc1/2 into the mechanotransduction complex in zebrafish hair cells is regulated by Transmembrane O-methyltransferase (Tomt). Elife 6: e28474.

Sheets L, He XJ, Olt J, Schreck M, Petralia RS, Wang YX, Zhang Q, Beirl A, Nicolson T, Marcotti W, Trapani JG, Kindt KS (2017) Enlargement of Ribbons in Zebrafish Hair Cells Increases Calcium Currents But Disrupts Afferent Spontaneous Activity and Timing of Stimulus Onset. J Neurosci 37: 6299-6313.

Waller R, Goodall EF, Milo M, Cooper-Knock J, Da Costa M, Hobson E, Kazoka M, Wollff H, Heath PR, Shaw P & Kirby J (2017) Serum miRNAs miR-206, 143-3p and 374b-5p as potential biomarkers for amyotrophic lateral sclerosis (ALS). Neurobiol of Aging, 55, 123-131.

Schomann T, Mezzanotte L, De Groot JCMJ, Rivolta MN, Hendriks SH, Frijns JHM, Huisman MA (2017) Neuronal differentiation of hair-follicle-bulge-derived stem cells co-cultured with mouse cochlear modiolus explants. PLoS ONE, 12(10).

Heimsath, EG Jr., Yim YI, Mustapha M, Hammer JA, and Cheney RE (2017) Myosin-X knockout is semi-lethal and demonstrates that myosin-X functions in neural tube closure, pigmentation, hyaloid vasculature regression, and filopodia formation. Scientific Reports, 7:17354.

For older publications see the individual PI websites