CDL301: Cardiovascular Pharmacology: Personalising Medicine.

CDL301 focuses on understanding cardiovascular pharmacology: the pharmacological principles associated with a variety of disease states and how treatment is personalised for individual patients. We hope that you find it interesting and enjoyable.

Module Aims

CDL301 aims to extend your knowledge and understanding of cardiovascular pharmacology as applied to ‘real-world’ (individual and patient/lifestyle based) clinical contexts. Particular emphasis will be placed upon network medicine, genomic strategies and personalising treatments for patients with heart disease.

Cardiovascular Personalised MedicineThe module will describe all aspects of modern cardiovascular pharmacology to enable the understanding of how and why medical treatments for cardiovascular disease are becoming increasingly personalised. Drugs that influence the function of the heart, blood vessels and blood cells in cardiovascular disease states and their interactions in humans will be discussed. The module will also explain new approaches to the multimodal treatment of heart disease. You will learn about cardiovascular pharmacology that is clinically very relevant, focusing on certain drugs/compounds that have a particular relevance for research e.g. having been used to elucidate mechanisms/pathways or are useful research tools.

Module Objectives

By the end of the module you should be able to meet the following general objectives:

  1. Describe and assess the molecular and cellular actions of drugs that affect the cardiovascular system.
  2. Classify the major cardiovascular drugs in current use by their actions at a cellular and molecular level.
  3. Evaluate the pharmacological basis for the treatment of major cardiovascular diseases and appreciate the common side effects that these drugs can produce.
  4. Show understanding of the importance of personalised medicine strategies for cardiovascular disease and how these are derived.
  5. Have knowledge of new and emerging pharmacological treatments for cardiovascular disease.
Module Co-Ordinators

CDL301 is administrated by Dr Janet Chamberlain, and co-ordinated by Professor Sheila Francis and Professor Nigel Wheeldon. Questions about this module should be addressed to Dr Janet Chamberlain (j.chamberlain@sheffield.ac.uk).

Teaching Methods

Teaching is by conventional lectures with topics supported by directed reading. The final session of the module involves an interactive critical analysis of a published paper.

Lecture slides are provided for download, and all lectures are recorded, with recording available online after the lectures. Students may also be directed to useful databases, clinical trial literature, or YouTube videos that help explain concepts. Private study, to ensure the understanding and assimilation of the material delivered by lectures, is recommended.

Janet Chamberlain Sheila Francis Nigel Wheeldon

Assessment

Formal assessment will be:

  • coursework (essay) 60%
  • examination 40%

The coursework will be an extended essay (from a choice of at least 3 titles) of 1500 words with a focus upon modern individualised pharmacological approaches in cardiovascular disease settings. This will test both specific knowledge imparted by the lectures and your ability to independently review the contemporary literature in the area.

The final examination will be short answer questions (approximately 8 in total, all compulsory) allowing around 10 minutes for each answer. The exam is expected to be 90 minutes in length. This will test breadth of knowledge, factual recall of lecture material, extra reading and the your ability to apply knowledge to real world cardiology/haematology settings.

In addition, there will be an on-line formative quiz (not examined) available to test your understanding of the lectures. The results of this quiz will not be officially recorded and this assessment activity is for your own benefit.

Feedback

This module provides feedback in a number of ways, including:

On-line resources: This module has an on-line quiz for you to do. The feedback (your score) on the quiz is provided as you complete it.

Module summary/journal club: This is an interactive session that offers an additional chance to test your knowledge. If you cannot answer questions asked during this session, then this is a guide to where gaps are in your understanding.

Generic feedback: This module will provide information regarding what is / was generally done well or poorly on the assessed essay as soon as is practicable after the hand-in of the work.

What do our students think?

93% of students (that responded to survey) would recommend the module to others.

93% found the module interesting.

92% said module helped develop understanding of cardiovascular pharmacology and personalised medicine.

CDL301 has been far more enjoyable than my other modules. Well laid out. Clear and concise. Obvious that time has been invested in organisation of the module.

2016 Student