Dr Guilhem Collier

All publications

Journal articles

• Niedbalski PJ, Hall CS, Castro M, Eddy RL, Rayment JH, Svenningsen S, Parraga G, Zanette B, Santyr GE, Thomen RP , Stewart NJ et al (2021) Protocols for multi-site trials using hyperpolarized 129 Xe MRI for imaging of ventilation, alveolar-airspace size, and gas exchange: A position paper from the 129 Xe MRI clinical trials consortium.. Magn Reson Med.
• Petersson-Sjögren M, Chan H-F, Collier GJ, Norquay G, Olsson LE, Wollmer P, Löndahl J & Wild JM (2021) Airspace Dimension Assessment (AiDA) by inhaled nanoparticles: benchmarking with hyperpolarised 129Xe diffusion-weighted lung MRI. Scientific Reports, 11. View this article in WRRO
• Chan H-F, Collier G, Parra-Robles J & Wild J (2021) Finite element simulations of hyperpolarized gas DWI in micro‐CT meshes of acinar airways: validating the cylinder and stretched exponential models of lung microstructural length scales. Magnetic Resonance in Medicine. View this article in WRRO
• Collier G, Eaden J, Hughes P, Bianchi S, Stewart N, Weatherley N, Norquay G, Schulte R & Wild J (2020) Dissolved 129Xe lung MRI with four‐echo 3D radial spectroscopic imaging: quantification of regional gas transfer in idiopathic pulmonary fibrosis. Magnetic Resonance in Medicine. View this article in WRRO
• Maunder A, Chan H-F, Hughes PJC, Collier G, Norquay G, Rodgers O, Thelwall P, Robb F, Rao M & Wild JM (2020) MR properties of 19 F C3 F8 gas in the lungs of healthy volunteers: T 2 ∗ and apparent diffusion coefficient at 1.5T and T 2 ∗ at 3T.. Magn Reson Med.
• Whitfield CA, Latimer P, Horsley A, Wild JM, Collier GJ & Jensen OE (2020) Spectral graph theory efficiently characterizes ventilation heterogeneity in lung airway networks: Spectral graph theory efficiently characterizes ventilation heterogeneity in lung airway networks. Journal of the Royal Society Interface, 17(168).
• Weatherley ND, Stewart NJ, Chan H-F, Austin M, Smith LJ, Collier G, Rao M, Marshall H, Norquay G, Renshaw SA , Bianchi SM et al (2019) Hyperpolarised xenon magnetic resonance spectroscopy for the longitudinal assessment of changes in gas diffusion in IPF. Thorax, 74(5), 500-502. View this article in WRRO
• Collier G, Hughes P, Horn F, Chan H-F, Tahir B, Norquay G, Stewart N & Wild J (2019) Single breath-held acquisition of co-registered 3D 129Xe lung ventilation and anatomical proton images of the human lung with compressed sensing. Magnetic Resonance in Medicine. View this article in WRRO
• Chan H-F, Weatherley N, Johns C, Stewart N, Collier G, Bianchi S & Wild J (2019) Airway microstructure in idiopathic pulmonary fibrosis: Assessment at hyperpolarized 3He diffusion-weighted MRI. Radiology, 291(1). View this article in WRRO
• Tahir BA, Marshall H, Hughes PJC, Brightling CE, Collier G, Ireland RH & Wild JM (2019) Comparison of CT ventilation imaging and hyperpolarised gas MRI: effects of breathing manoeuvre.. Physics in Medicine and Biology. View this article in WRRO
• Marshall H, Collier GJ, Johns CS, Chan H, Norquay G, Lawson RA & Wild JM (2019) Imaging Collateral Ventilation in Patients With Advanced Chronic Obstructive Pulmonary Disease: Relative Sensitivity of 3 He and 129 Xe MRI. Journal of Magnetic Resonance Imaging, 49(4), 1195-1197. View this article in WRRO
• Chan H, Collier G, Weatherley N & Wild J (2018) Comparison of in vivo lung morphometry models from 3D multiple b-value 3He and 129Xe diffusion-weighted MRI. Magnetic Resonance in Medicine. View this article in WRRO
• Tahir BA, Hughes P, Robinson S, Marshall H, Stewart N, Norquay G, Biancardi A, Chan H, Collier GJ, Hart KA , Swinscoe JA et al (2018) Spatial Comparison of CT-Based Surrogates of Lung Ventilation With Hyperpolarized Helium-3 and Xenon-129 Gas MRI in Patients Undergoing Radiation Therapy. International Journal of Radiation Oncology, Biology, Physics, 102(4), 1276-1286. View this article in WRRO
• Hughes PJC, Smith L, Chan H-F, Tahir BA, Norquay G, Collier GJ, Biancardi AM, Marshall H & Wild JM (2018) Assessment of the influence of lung inflation state on the quantitative parameters derived from hyperpolarized gas lung ventilation MRI in healthy volunteers.. Journal of Applied Physiology. View this article in WRRO
• Smith LJ, Collier GJ, Marshall H, Hughes PJC, Biancardi AM, Wildman M, Aldag I, West N, Horsley A & Wild JM (2018) Patterns of regional lung physiology in cystic fibrosis using ventilation magnetic resonance imaging and multiple-breath washout.. European Respiratory Journal, 52(5). View this article in WRRO
• Collier GJ, Kim M, Chung Y & Wild JM (2018) 3D phase contrast MRI in models of human airways: Validation of computational fluid dynamics simulations of steady inspiratory flow. Journal of Magnetic Resonance Imaging, 48(5), 1400-1409. View this article in WRRO
• Norquay G, Collier G, Rao M, Stewart N & Wild J (2018) 129 Xe-Rb Spin-Exchange Optical Pumping with High Photon Efficiency. Physical Review Letters, 121(15). View this article in WRRO
• Arai TJ, Horn FC, Sá RC, Rao MR, Collier GJ, Theilmann RJ, Prisk GK & Wild JM (2018) Comparison of Quantitative Multiple Breath Specific Ventilation Imaging Using Co-localized 2D Oxygen Enhanced MRI and Hyperpolarized 3He MRI.. Journal of Applied Physiology. View this article in WRRO
• Kim M, Collier GJ, Wild JM & Chung YM (2018) Effect of upper airway on tracheobronchial fluid dynamics. International Journal for Numerical Methods in Biomedical Engineering, 34(9), e3112-e3112. View this article in WRRO
• Smith LJ, West N, Hughes D, Marshall H, Johns CS, Stewart NJ, Chan H-F, Rao M, Capener DJ, Bray J , Collier GJ et al (2018) Imaging Lung Function Abnormalities in Primary Ciliary Dyskinesia Using Hyperpolarized Gas Ventilation MRI. Annals of the American Thoracic Society, 15(12), 1487-1490. View this article in WRRO
• Stewart NJ, Chan H-F, Hughes PJC, Horn FC, Norquay G, Rao M, Yates DP, Ireland RH, Hatton MQ, Tahir BA , Ford P et al (2018) Comparison of 3 He and 129 Xe MRI for evaluation of lung microstructure and ventilation at 1.5T. Journal of Magnetic Resonance Imaging, 48(3), 632-642. View this article in WRRO
• Smith L, Marshall H, Aldag I, Horn F, Collier G, Hughes D, West N, Horsley A, Taylor CJ & Wild J (2018) Longitudinal Assessment of Children with Mild CF Using Hyperpolarised Gas Lung MRI and LCI. American Journal of Respiratory and Critical Care Medicine, 197(3). View this article in WRRO
• Chan H-F, Stewart NJ, Norquay G, Collier GJ & Wild JM (2018) 3D diffusion-weighted 129 Xe MRI for whole lung morphometry. Magnetic Resonance in Medicine, 79(6), 2986-2995. View this article in WRRO
• Smith LJ, Macleod KA, Collier GJ, Horn FC, Sheridan H, Aldag I, Taylor CJ, Cunningham S, Wild JM & Horsley A (2017) Supine posture changes lung volumes and increases ventilation heterogeneity in cystic fibrosis. PLoS ONE, 12(11). View this article in WRRO
• Chan H-F, Parra-Robles J, Collier G & Wild J (2017) Comparison of in-vivo lung morphometry models from multiple b-value diffusion-weighted MRI in healthy controls, IPF and COPD patients. Imaging. View this article in WRRO
• Horn FC, Marshall H, Collier GJ, Kay R, Siddiqui S, Brightling CE, Parra-Robles J & Wild JM (2017) Regional Ventilation Changes in the Lung: Treatment Response Mapping by Using Hyperpolarized Gas MR Imaging as a Quantitative Biomarker. Radiology, 284(3). View this article in WRRO
• Hughes PJC, Horn FC, Collier GJ, Biancardi A, Marshall H & Wild JM (2017) Spatial fuzzy c-means thresholding for semiautomated calculation of percentage lung ventilated volume from hyperpolarized gas and (1) H MRI. Journal of Magnetic Resonance Imaging. View this article in WRRO
• Chan HF, Stewart NJ, Parra-Robles J, Collier GJ & Wild JM (2017) Whole lung morphometry with 3D multiple b‐value hyperpolarized gas MRI and compressed sensing. Magnetic Resonance in Medicine, 77(5), 1916-1925. View this article in WRRO
• Marshall H, Horsley A, Taylor CJ, Smith L, Hughes D, Horn FC, Swift AJ, Parra-Robles J, Hughes PJ, Norquay G , Stewart NJ et al (2017) Detection of early subclinical lung disease in children with cystic fibrosis by lung ventilation imaging with hyperpolarised gas MRI. Thorax, 72(8), 760-762. View this article in WRRO
• Stewart NJ, Horn FC, Norquay G, Collier GJ, Yates DP, Lawson R, Marshall H & Wild JM (2016) Reproducibility of quantitative indices of lung function and microstructure from 129Xe chemical shift saturation recovery (CSSR) MR spectroscopy. Magnetic Resonance in Medicine. View this article in WRRO
• Swift AJ, Saunders LC, Sproson T, Hussain N, Collier GJ, Marshall H, Kiely DG & Wild JM (2015) Multiparametric Magnetic Resonance Imaging in Pulmonary Hypertension. Current Cardiovascular Imaging Reports, 8(12).
• Collier GJ, Marshall H, Rao M, Stewart NJ, Capener D & Wild JM (2015) Observation of cardiogenic flow oscillations in healthy subjects with hyperpolarized 3 He MRI. Journal of Applied Physiology, 119(9), 1007-1014. View this article in WRRO
• Collier GJ & Wild JM (2015) In vivo measurement of gas flow in human airways with hyperpolarized gas MRI and compressed sensing.. Magn Reson Med, 73(6), 2255-2261. View this article in WRRO
• Horn FC, Tahir BA, Stewart NJ, Collier GJ, Norquay G, Leung G, Ireland RH, Parra-Robles J, Marshall H & Wild JM (2014) Lung ventilation volumetry with same-breath acquisition of hyperpolarized gas and proton MRI. NMR in Biomedicine, 27(12), 1461-1467. View this article in WRRO
• Boussaoud A, Fonteille I, Collier G, Kermarrec F, Vermont F, Tresallet E, De Waard M, Arnoult C & Picollet-D’hahan N (2012) A miniaturized planar patch-clamp system for transportable use. Biosensors and Bioelectronics, 32(1), 96-103.
• Stewart NJ, Smith LJ, Chan H-F, Eaden JA, Rajaram S, Swift AJ, Weatherley ND, Biancardi A, Collier GJ, Hughes D , Klafkowski G et al () Lung MRI with hyperpolarised gases: current & future clinical perspectives. The British Journal of Radiology, 20210207-20210207.
• Grist JT, Chen M, Collier GJ, Raman B, AbuEid G, McIntyre A, Matthews V, Fraser E, Ho L-P, Wild JM & Gleeson F () Hyperpolarized 129Xe MRI Abnormalities in Dyspneic Participants 3 Months after COVID-19 Pneumonia: Preliminary Results. Radiology, 210033-210033.
• Whitfield CA, Latimer P, Horsley A, Wild JM, Collier GJ & Jensen OE () Spectral graph theory efficiently characterises ventilation heterogeneity in lung airway networks.
• Puddu C, Rao M, Xu X, Deppe MH, Collier G, Maunder A, Chan H, De Zanche N, Robb F & Wild JM () An asymmetrical whole‐body birdcage RF coil without RF shield for hyperpolarized 129 Xe lung MR imaging at 1.5 T. Magnetic Resonance in Medicine.
• Mussell G, Marshall H, Smith L, Biancardi A, Hughes P, Capener D, Bray J, Swift A, Rajaram S, Condliffe A , Collier G et al () Xenon ventilation MRI in difficult asthma; initial experience in a clinical setting. European Respiratory Journal.

Chapters

• Albert MS, Altes TA, Anthony D, Barlow MJ, Bueno J, Chekmenev EY, Clapp J, Coffey AM, Collier GJ, Couch MJ , de Lange EE et al (2017) List of Contributors, Hyperpolarized and Inert Gas MRI (pp. xi-xii). Elsevier
• Wild JM, Horn FC, Collier GJ & Marshall H (2017) Dynamic Imaging of Lung Ventilation and Gas Flow With Hyperpolarized Gas MRI, Hyperpolarized and Inert Gas MRI (pp. 47-59). Elsevier

Conference proceedings papers

• Eaden JA, Collier GJ, Norquay G, Chan H-F, Hughes PJC, Weatherley ND, Rajaram S, Swift A, Leonard CT, Skeoch S , Chaudhuri N et al (2021) S75 Hyperpolarised 129-xenon MRI in differentiating between fibrotic and inflammatory interstitial lung disease and assessing longitudinal change. Basic science in ILD: what drives progression?
• Astley J, Biancardi A, Hughes P, Smith L, Marshall H, Eaden J, Bray J, Weatherley N, Collier G, Wild J & Tahir B (2020) 3D deep convolutional neural network-based ventilated lung segmentation using multi-nuclear hyperpolarized gas MRI. Thoracic Image Analysis, Vol. 12502 (pp 24-35). Lima, Peru, 8 October 2020 - 8 October 2020. View this article in WRRO
• Chan H-F, Petersson Sjögren M, Hughes P, Rodgers O, Collier G, Norquay G, Olsson L, Wollmer P, Wild J & Löndahl J (2020) Benchmarking inhaled nanoparticle measurements of airspace dimension with hyperpolarised 129Xe diffusion-weighted MRI. Imaging
• Whitfield C, Smith L, Jensen O, West N, Wildman M, Collier G, Wild J & Horsley A (2020) Interpretation of multiple breath washout (MBW) measurements of lung function using mathematical modelling and hyperpolarised 3He gas MRI. Respiratory infections
• Smith L, Hughes D, Chan H-F, Johnson K, Bray J, Rodgers O, Collier G, Norquay G, Biancardi A, Hughes P , Kotecha S et al (2019) 1H and 129Xe MRI to detect functional and structural lung disease in sub-clinical cystic fibrosis. Cystic fibrosis
• Smith L, Collier G, Marshall H, Hughes P, Biancardi A, Norquay G, Bray J, Rodgers O, Wildman M, West N , Horsley A et al (2019) Clinical applicability of 3He and 129Xe ventilation MRI in cystic fibrosis: longitudinal follow up. Cystic fibrosis
• Wild JM, Biancardi A, Chan H-F, Smith L, Bray J, Marshall H, Collier G, Norquay G, Hughes P, Swift A , Cousins M et al (2019) Imaging functional and microstructural changes in the lungs of children born prematurely. Imaging
• Eaden J, Hughes P, Collier G, Norquay G, Weatherly N, Austin M, Smith L, Lithgow J, Swift A, Renshaw S , Buch M et al (2019) Longitudinal change in hyperpolarised 129-xenon MR spectroscopy in interstitial lung disease. Imaging
• Mussell G, Marshall H, Smith L, Biancardi A, Hughes P, Swift A, Collier G, Wild J & Sabroe I (2019) Correlations of ventilation heterogeneity and spirometry in asthma; initial experience with hyperpolarised gas MRI in a clinical setting. Imaging
• Whitfield C, Horsley A, Jensen O, Horn F, Smith L, Collier G & Wild J (2019) Predicting multiple breath washout outcomes from hyperpolarised gas magnetic resonance imaging (MRI). Imaging
• Smith L, Collier G, Marshall H, Hughes P, Biancardi A, Norquay G, Bray J, Rodgers O, Wildman M, West N , Horsley A et al (2019) P213 A comparison of ventilation MRI using hyperpolarised 3He and 129Xe to assess cystic fibrosis lung disease. Journal of Cystic Fibrosis, Vol. 18 (pp S117-S117)
• Smith L, Marshall H, Norquay G, Collier G, Rodgers O, Hughes P, Biancardi A, West N, Wildman M, Horsley A & Wild J (2019) P211 129Xe ventilation MRI and LCI to assess acute maximal exercise as a method of airway clearance. Journal of Cystic Fibrosis, Vol. 18 (pp S116-S117)
• Smith L, Collier G, Marshall H, Hughes P, Biancardi A, Norquay G, Bray J, Rodgers O, Wildman M, West N , Horsley A et al (2019) P212 Ventilation MRI tracks longitudinal lung function changes in patients with cystic fibrosis and clinically stable FEV1 and Lung Clearance Index. Journal of Cystic Fibrosis, Vol. 18 (pp S117-S117)
• Smith L, Hughes D, Chan H-F, Johnson K, Bray J, Rodgers O, Collier G, Norquay G, Biancardi A, Hughes P , Kotecha S et al (2019) WS17-2 The sensitivity of MRI to detect both functional and structural lung abnormalities in sub-clinical cystic fibrosis. Journal of Cystic Fibrosis, Vol. 18 (pp S32-S32)
• Weatherley ND, Stewart NJ, Chan HF, Hughes PJC, Marshall H, Austin M, Smith L, Collier G, Rao M, Norquay G , Renshaw SA et al (2018) Probing diffusion and perfusion in idiopathic pulmonary fibrosis with hyperpolarised xenon and dynamic contrast-enhanced magnetic resonance imaging. Thorax, Vol. 73(Suppl 4) (pp A44-A45). London, UK, 5 December 2018 - 7 December 2018. View this article in WRRO
• Smith L, Collier G, Marshall H, Hughes P, Bray J, Rodgers O, Aldag I, West N, Wildman M, Horsley A & Wild J (2018) The effect of inhaled lung volume on ventilation heterogeneity in CF using 3He MRI. Cystic fibrosis
• Tahir B, Hughes P, Robinson S, Marshall H, Stewart N, Biancardi A, Chan HF, Collier G, Hart K, Swinscoe J , Hatton M et al (2018) OC-0182: A comparison of CT ventilation with 3He and 129Xe MRI for functional avoidance treatment planning. Radiotherapy and Oncology, Vol. 127(Supplement 1) (pp S96-S97). Barcelona, Spain, 20 April 2018 - 24 April 2018. View this article in WRRO
• West N, Smith L, Chan H-F, Horn F, Chetcuti P, Moya E, Marshall H, Wild J, Norquay G, Collier G & Rao M (2017) Hyperpolarised gas ventilation MRI detects early lung ventilation heterogeneity in children with primary ciliary dyskinesia. Paediatric Respiratory Physiology and Sleep
• Weatherley N, Chan H-F, Stewart N, Norquay G, Rao M, Collier G, Austin M, Smith L, Marshall H, Renshaw SA , Bianchi S et al (2017) Late breaking abstract - Hyperpolarised gas MRI demonstrates sub-clinical progression in IPF over 6 months. European Respiratory Journal, Vol. 50(Suppl 61). Milan, Italy, 9 September 2017 - 13 September 2017. View this article in WRRO
• Hughes P, Smith L, Horn F, Biancardi A, Collier G, Stewart N, Norquay G, Rao M, Aldag I, Taylor C , Marshall H et al (2017) Ventilation heterogeneity assessed in patients with mild cystic fibrosis and asthma using Hyperpolarised gas MRI histogram analysis. Imaging
• Chan H-F, Collier G, Smith L, Marshall H, Hughes P, Parra-Robles J, Horn F, Norquay G, Stewart N, Taylor C , Aldag I et al (2017) Longitudinal monitoring of lung microstructure with HP gas diffusion-weighted MRI in mild cystic fibrosis children. Cystic Fibrosis View this article in WRRO
• Horn F, Collier G, Chan H-F, Stewart N & Wild J (2016) Regional phase III slope measurement using hyperpolarized gas MR imaging. 1.3 Imaging View this article in WRRO
• Weatherley N, Chan F, Stewart N, Saunders L, Collier G, Norquay G, Rao M, Austin M, Bianchi S & Wild J (2016) Diffusion-weighted hyperpolarised gas MRI in idiopathic pulmonary fibrosis : reproducibility and clinical significance. ERS International Congress 2016 abstracts, Vol. 48(Suppl 60). London, UK, 3 September 2016 - 7 September 2016. View this article in WRRO
• Smith L, Aldag I, Hughes P, Horn F, Marshall H, Norquay G, Collier G, Hughes D, Taylor C, Horsley A & Wild J (2016) Longitudinal monitoring of disease progression in children with mild CF using hyperpolarised gas MRI and LCI. 9.1 Respiratory Function Technologists/Scientists View this article in WRRO
• Smith L, Horn F, Marshall H, Collier G, Hughes P, Aldag I, Taylor C, Horsley A & Wild J (2016) Comparison of phase III slope analysis from MBW with hyperpolarised gas MRI in children with mild CF. 9.1 Respiratory Function Technologists/Scientists
• Tahir B, Marshall H, Hughes P, Stewart N, Horn F, Collier G, Norquay G, Hart K, Swinscoe J, Hatton M , Wild J et al (2016) Ventilation CT : voxel-level comparison with HP gas MRI. European Respiratory Journal, Vol. 48(Suppl 60). Estoril, Portugal, 10 March 2016 - 13 March 2016. View this article in WRRO
• Stewart N, Chan H-F, Hughes P, Collier G, Horn F, Norquay G, Parra-Robles J, Yates D, Collini P, Lawson R , Marshall H et al (2016) Comparison of 3 He and 129 Xe MRI for evaluation of lung microstructure and ventilation at 1.5 T. European Respiratory Journal, Vol. 48(suppl 60), 3 September 2016 - 7 September 2016. View this article in WRRO
• Tahir B, Marshall H, Hughes P, Stewart N, Horn F, Collier G, Norquay G, Hart K, Swinscoe J, Hatton M , Wild J et al (2016) WE-AB-202-07: Ventilation CT: Voxel-Level Comparison with Hyperpolarized Helium-3 & Xenon-129 MRI. Medical Physics, Vol. 43(6) (pp 3795-3796), 31 July 2016 - 4 August 2016. View this article in WRRO
• Aldag I, Marshall H, Taylor C, Horsley A, Hughes D, Smith L, Horn F, Swift A, Parra-Robles J, Hughes P , Collier G et al (2016) WS15.2 Multiple breath washout and imaging with 3 He MRI and CT scans to monitor early-stage lung disease in patients with cystic fibrosis. Journal of Cystic Fibrosis, Vol. 15 (pp S24-S25)
• Wild JM, Collier G, Marshall H, Smith L, Norquay G, Swift AJ, Horn FC, Chan F, Stewart NJ, Hutchison LC , Rao M et al (2015) P283 Hyperpolarised Gas MRI – a pathway to Clinical Diagnostic Imaging. Thorax, Vol. 70(Suppl 3) (pp A220.3-A221)
• Weatherley ND, Stewart NJ, Marshall H, Collier G, Hart K, Horn F, Norquay G, Whyte MK, Bianchi S & Wild JM (2015) P286 Correlations of functional multi-nuclear MR imaging indices with pulmonary function tests in the assessment of idiopathic pulmonary fibrosis. Thorax, Vol. 70(Suppl 3) (pp A223.1-A223)
• Wild J, Smith L, Horn F, Collier G, Swift A, Stewart N, Rao M, Norquay G, Hughes D, Ugonna K & Marshall H (2015) Hyperpolarised gas MR lung imaging – Breaks through to clinical practice. 1.3 Imaging

Other

• (2016) Commentaries on Viewpoint: Could lobar flow sequencing account for convection-dependent ventilation heterogeneity in normal humans?. Journal of Applied Physiology, 121(2), 592-592. View this article in WRRO