Dr Guilhem Collier

All publications

Journal articles

• Vaeggemose M, Kristensen MH, Redda M, Hansen ESS, Rodgers O, Collier GJ, Norquay G, Wild JM, Laustsen C & Schulte RF (2025) MR spectroscopic imaging of hyperpolarized 129‐xenon in the dissolved‐phase to determine regional chemical shifts of hyperoxia in healthy porcine lungs. NMR in Biomedicine, 38(6). View this article in WRRO
• Diamond VM, Bell LC, Bone JN, Driehuys B, Menchaca M, Santyr G, Svenningsen S, Thomen RP, Marshall H, Smith LJ , Collier GJ et al (2025) A systematic review of the variability of ventilation defect percent generated from hyperpolarized noble gas pulmonary magnetic resonance imaging. Journal of Magnetic Resonance Imaging. View this article in WRRO
• Filkins M, Harrison A, Collier GJ, Norquay G, Wild JM, Rigby SP, Pavlovskaya GE & Meersmann T (2024) A standardized MRI phantom for dissolved phase 129Xe MRI. Journal of Magnetic Resonance Open, 21, 100175-100175.
• Pilgrim‐Morris JH, Collier GJ, Munro RS, Norquay G, Stewart NJ & Wild JM (2024) Compressed sensing reconstruction for high-SNR, rapid dissolved 129Xe gas exchange MRI. Magnetic Resonance in Medicine.
• Wild JM, Gleeson FV, Svenningsen S, Grist JT, Saunders LC, Collier GJ, Sharma M, Tcherner S, Mozaffaripour A, Matheson AM & Parraga G (2024) Review of Hyperpolarized Pulmonary Functional ¹²⁹Xe MR for Long‐COVID. Journal of Magnetic Resonance Imaging, 59(4).
• Astley JR, Biancardi AM, Marshall H, Smith LJ, Hughes PJC, Collier GJ, Saunders LC, Norquay G, Tofan M-M, Hatton MQ , Hughes R et al (2023) PhysVENeT: a physiologically-informed deep learning-based framework for the synthesis of 3D hyperpolarized gas MRI ventilation. Scientific Reports, 13.
• Astley JR, Biancardi AM, Marshall H, Hughes PJC, Collier GJ, Hatton MQ, Wild JM & Tahir BA (2023) A hybrid model‐ and deep learning‐based framework for functional lung image synthesis from multi‐inflation CT and hyperpolarized gas MRI. Medical Physics.
• Saunders LC, Collier GJ, Chan H-F, Hughes PJC, Smith LJ, Watson J, Meiring J, Gabriel Z, Newman T, Plowright M , Wade P et al (2023) Longitudinal lung function assessment of patients hospitalised with COVID-19 using 1H and 129Xe lung MRI. Chest.
• Astley JR, Biancardi AM, Hughes PJC, Marshall H, Collier GJ, Chan H, Saunders LC, Smith LJ, Brook ML, Thompson R , Rowland‐Jones S et al (2023) Implementable deep learning for multi-sequence proton MRI lung segmentation: a multi-center, multi-vendor, and multi-disease study. Journal of Magnetic Resonance Imaging.
• Collier GJ, Schulte RF, Rao M, Norquay G, Ball J & Wild JM (2023) Imaging gas-exchange lung function and brain tissue uptake of hyperpolarized 129Xe using sampling density-weighted MRSI. Magnetic Resonance in Medicine.
• Chan H-F, Smith LJ, Biancardi AM, Bray J, Marshall H, Hughes PJC, Collier GJ, Rao M, Norquay G, Swift AJ , Hart K et al (2022) Image phenotyping of preterm-born children using hyperpolarised 129Xe lung MRI and multiple-breath washout. American Journal of Respiratory and Critical Care Medicine. View this article in WRRO
• Astley JR, Biancardi AM, Hughes PJC, Marshall H, Smith LJ, Collier GJ, Eaden JA, Weatherley ND, Hatton MQ, Wild JM & Tahir BA (2022) Large-scale investigation of deep learning approaches for ventilated lung segmentation using multi-nuclear hyperpolarized gas MRI. Scientific Reports, 12(1). View this article in WRRO
• Grist JT, Collier GJ, Walters H, Kim M, Chen M, Abu Eid G, Laws A, Matthews V, Jacob K, Cross S , Eves A et al (2022) Lung abnormalities depicted with hyperpolarized Xenon MRI in patients with Long COVID. Radiology. View this article in WRRO
• Whitfield CA, Horsley A, Jensen OE, Horn FC, Collier GJ, Smith LJ & Wild JM (2022) Model-based Bayesian inference of the ventilation distribution in patients with cystic fibrosis from multiple breath washout, with comparison to ventilation MRI.. Respir Physiol Neurobiol, 302, 103919.
• Norquay G, Collier GJ, Rodgers OI, Gill AB, Screaton NJ & Wild J (2022) Standalone portable xenon-129 hyperpolariser for multicentre clinical magnetic resonance imaging of the lungs. The British Journal of Radiology, 95(1132).
• Wild JM, Porter JC, Molyneaux PL, George PM, Stewart I, Allen RJ, Aul R, Baillie JK, Barratt SL, Beirne P , Bianchi SM et al (2021) Understanding the burden of interstitial lung disease post-COVID-19: the UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID). BMJ Open Respiratory Research, 8(1).
• Niedbalski PJ, Hall CS, Castro M, Eddy RL, Rayment JH, Svenningsen S, Parraga G, Zanette B, Santyr GE, Thomen RP , Stewart NJ et al (2021) Protocols for multi-site trials using hyperpolarized 129 Xe MRI for imaging of ventilation, alveolar-airspace size, and gas exchange: A position paper from the 129 Xe MRI clinical trials consortium.. Magn Reson Med.
• Petersson-Sjögren M, Chan H-F, Collier GJ, Norquay G, Olsson LE, Wollmer P, Löndahl J & Wild JM (2021) Airspace Dimension Assessment (AiDA) by inhaled nanoparticles: benchmarking with hyperpolarised 129Xe diffusion-weighted lung MRI. Scientific Reports, 11. View this article in WRRO
• Chan H-F, Collier G, Parra-Robles J & Wild J (2021) Finite element simulations of hyperpolarized gas DWI in micro‐CT meshes of acinar airways: validating the cylinder and stretched exponential models of lung microstructural length scales. Magnetic Resonance in Medicine. View this article in WRRO
• Collier G, Eaden J, Hughes P, Bianchi S, Stewart N, Weatherley N, Norquay G, Schulte R & Wild J (2020) Dissolved 129Xe lung MRI with four‐echo 3D radial spectroscopic imaging: quantification of regional gas transfer in idiopathic pulmonary fibrosis. Magnetic Resonance in Medicine. View this article in WRRO
• Maunder A, Chan H-F, Hughes PJC, Collier G, Norquay G, Rodgers O, Thelwall P, Robb F, Rao M & Wild JM (2020) MR properties of 19 F C3 F8 gas in the lungs of healthy volunteers: T 2 ∗ and apparent diffusion coefficient at 1.5T and T 2 ∗ at 3T.. Magn Reson Med.
• Whitfield CA, Latimer P, Horsley A, Wild JM, Collier GJ & Jensen OE (2020) Spectral graph theory efficiently characterizes ventilation heterogeneity in lung airway networks: Spectral graph theory efficiently characterizes ventilation heterogeneity in lung airway networks. Journal of the Royal Society Interface, 17(168).
• Weatherley ND, Stewart NJ, Chan H-F, Austin M, Smith LJ, Collier G, Rao M, Marshall H, Norquay G, Renshaw SA , Bianchi SM et al (2019) Hyperpolarised xenon magnetic resonance spectroscopy for the longitudinal assessment of changes in gas diffusion in IPF. Thorax, 74(5), 500-502. View this article in WRRO
• Collier G, Hughes P, Horn F, Chan H-F, Tahir B, Norquay G, Stewart N & Wild J (2019) Single breath-held acquisition of co-registered 3D 129Xe lung ventilation and anatomical proton images of the human lung with compressed sensing. Magnetic Resonance in Medicine. View this article in WRRO
• Chan H-F, Weatherley N, Johns C, Stewart N, Collier G, Bianchi S & Wild J (2019) Airway microstructure in idiopathic pulmonary fibrosis: Assessment at hyperpolarized 3He diffusion-weighted MRI. Radiology, 291(1). View this article in WRRO
• Tahir BA, Marshall H, Hughes PJC, Brightling CE, Collier G, Ireland RH & Wild JM (2019) Comparison of CT ventilation imaging and hyperpolarised gas MRI: effects of breathing manoeuvre.. Physics in Medicine and Biology. View this article in WRRO
• Marshall H, Collier GJ, Johns CS, Chan H, Norquay G, Lawson RA & Wild JM (2019) Imaging Collateral Ventilation in Patients With Advanced Chronic Obstructive Pulmonary Disease: Relative Sensitivity of 3 He and 129 Xe MRI. Journal of Magnetic Resonance Imaging, 49(4), 1195-1197. View this article in WRRO
• Chan H, Collier G, Weatherley N & Wild J (2018) Comparison of in vivo lung morphometry models from 3D multiple b-value 3He and 129Xe diffusion-weighted MRI. Magnetic Resonance in Medicine. View this article in WRRO
• Tahir BA, Hughes P, Robinson S, Marshall H, Stewart N, Norquay G, Biancardi A, Chan H, Collier GJ, Hart KA , Swinscoe JA et al (2018) Spatial Comparison of CT-Based Surrogates of Lung Ventilation With Hyperpolarized Helium-3 and Xenon-129 Gas MRI in Patients Undergoing Radiation Therapy. International Journal of Radiation Oncology, Biology, Physics, 102(4), 1276-1286. View this article in WRRO
• Hughes PJC, Smith L, Chan H-F, Tahir BA, Norquay G, Collier GJ, Biancardi AM, Marshall H & Wild JM (2018) Assessment of the influence of lung inflation state on the quantitative parameters derived from hyperpolarized gas lung ventilation MRI in healthy volunteers.. Journal of Applied Physiology. View this article in WRRO
• Smith LJ, Collier GJ, Marshall H, Hughes PJC, Biancardi AM, Wildman M, Aldag I, West N, Horsley A & Wild JM (2018) Patterns of regional lung physiology in cystic fibrosis using ventilation magnetic resonance imaging and multiple-breath washout.. European Respiratory Journal, 52(5). View this article in WRRO
• Collier GJ, Kim M, Chung Y & Wild JM (2018) 3D phase contrast MRI in models of human airways: Validation of computational fluid dynamics simulations of steady inspiratory flow. Journal of Magnetic Resonance Imaging, 48(5), 1400-1409. View this article in WRRO
• Norquay G, Collier G, Rao M, Stewart N & Wild J (2018) 129 Xe-Rb Spin-Exchange Optical Pumping with High Photon Efficiency. Physical Review Letters, 121(15). View this article in WRRO
• Arai TJ, Horn FC, Sá RC, Rao MR, Collier GJ, Theilmann RJ, Prisk GK & Wild JM (2018) Comparison of Quantitative Multiple Breath Specific Ventilation Imaging Using Co-localized 2D Oxygen Enhanced MRI and Hyperpolarized 3He MRI.. Journal of Applied Physiology. View this article in WRRO
• Kim M, Collier GJ, Wild JM & Chung YM (2018) Effect of upper airway on tracheobronchial fluid dynamics. International Journal for Numerical Methods in Biomedical Engineering, 34(9), e3112-e3112. View this article in WRRO
• Smith LJ, West N, Hughes D, Marshall H, Johns CS, Stewart NJ, Chan H-F, Rao M, Capener DJ, Bray J , Collier GJ et al (2018) Imaging Lung Function Abnormalities in Primary Ciliary Dyskinesia Using Hyperpolarized Gas Ventilation MRI. Annals of the American Thoracic Society, 15(12), 1487-1490. View this article in WRRO
• Stewart NJ, Chan H-F, Hughes PJC, Horn FC, Norquay G, Rao M, Yates DP, Ireland RH, Hatton MQ, Tahir BA , Ford P et al (2018) Comparison of 3 He and 129 Xe MRI for evaluation of lung microstructure and ventilation at 1.5T. Journal of Magnetic Resonance Imaging, 48(3), 632-642. View this article in WRRO
• Smith L, Marshall H, Aldag I, Horn F, Collier G, Hughes D, West N, Horsley A, Taylor CJ & Wild J (2018) Longitudinal Assessment of Children with Mild CF Using Hyperpolarised Gas Lung MRI and LCI. American Journal of Respiratory and Critical Care Medicine, 197(3). View this article in WRRO
• Chan H-F, Stewart NJ, Norquay G, Collier GJ & Wild JM (2018) 3D diffusion-weighted 129 Xe MRI for whole lung morphometry. Magnetic Resonance in Medicine, 79(6), 2986-2995. View this article in WRRO
• Smith LJ, Macleod KA, Collier GJ, Horn FC, Sheridan H, Aldag I, Taylor CJ, Cunningham S, Wild JM & Horsley A (2017) Supine posture changes lung volumes and increases ventilation heterogeneity in cystic fibrosis. PLoS ONE, 12(11). View this article in WRRO
• Chan H-F, Parra-Robles J, Collier G & Wild J (2017) Comparison of in-vivo lung morphometry models from multiple b-value diffusion-weighted MRI in healthy controls, IPF and COPD patients. Imaging. View this article in WRRO
• Horn FC, Marshall H, Collier GJ, Kay R, Siddiqui S, Brightling CE, Parra-Robles J & Wild JM (2017) Regional Ventilation Changes in the Lung: Treatment Response Mapping by Using Hyperpolarized Gas MR Imaging as a Quantitative Biomarker. Radiology, 284(3). View this article in WRRO
• Hughes PJC, Horn FC, Collier GJ, Biancardi A, Marshall H & Wild JM (2017) Spatial fuzzy c-means thresholding for semiautomated calculation of percentage lung ventilated volume from hyperpolarized gas and (1) H MRI. Journal of Magnetic Resonance Imaging. View this article in WRRO
• Chan HF, Stewart NJ, Parra-Robles J, Collier GJ & Wild JM (2017) Whole lung morphometry with 3D multiple b‐value hyperpolarized gas MRI and compressed sensing. Magnetic Resonance in Medicine, 77(5), 1916-1925. View this article in WRRO
• Marshall H, Horsley A, Taylor CJ, Smith L, Hughes D, Horn FC, Swift AJ, Parra-Robles J, Hughes PJ, Norquay G , Stewart NJ et al (2017) Detection of early subclinical lung disease in children with cystic fibrosis by lung ventilation imaging with hyperpolarised gas MRI. Thorax, 72(8), 760-762. View this article in WRRO
• Stewart NJ, Horn FC, Norquay G, Collier GJ, Yates DP, Lawson R, Marshall H & Wild JM (2016) Reproducibility of quantitative indices of lung function and microstructure from 129Xe chemical shift saturation recovery (CSSR) MR spectroscopy. Magnetic Resonance in Medicine. View this article in WRRO
• Swift AJ, Saunders LC, Sproson T, Hussain N, Collier GJ, Marshall H, Kiely DG & Wild JM (2015) Multiparametric Magnetic Resonance Imaging in Pulmonary Hypertension. Current Cardiovascular Imaging Reports, 8(12).
• Collier GJ, Marshall H, Rao M, Stewart NJ, Capener D & Wild JM (2015) Observation of cardiogenic flow oscillations in healthy subjects with hyperpolarized 3 He MRI. Journal of Applied Physiology, 119(9), 1007-1014. View this article in WRRO
• Collier GJ & Wild JM (2015) In vivo measurement of gas flow in human airways with hyperpolarized gas MRI and compressed sensing.. Magn Reson Med, 73(6), 2255-2261. View this article in WRRO
• Horn FC, Tahir BA, Stewart NJ, Collier GJ, Norquay G, Leung G, Ireland RH, Parra-Robles J, Marshall H & Wild JM (2014) Lung ventilation volumetry with same-breath acquisition of hyperpolarized gas and proton MRI. NMR in Biomedicine, 27(12), 1461-1467. View this article in WRRO
• Boussaoud A, Fonteille I, Collier G, Kermarrec F, Vermont F, Tresallet E, De Waard M, Arnoult C & Picollet-D’hahan N (2012) A miniaturized planar patch-clamp system for transportable use. Biosensors and Bioelectronics, 32(1), 96-103.
• Smith LJ, Marshall H, Jakymelen D, Biancardi A, Collier GJ, Chan H-F, Hughes PJC, Brook ML, Astley JR, Munro R , Rajaram S et al () ¹²⁹Xe-MRI ventilation and acinar abnormalities highlight the significance of spirometric dysanapsis: findings from the NOVELTY ADPro UK substudy. Thorax.
• Driehuys B, Zhang S, Bechtel A, Hahn AD, Collier G, Niedbalski PJ, Huang Y, Cleveland ZI, Willmering MM, Mugler JP , Mata J et al () Design and Implementation of a Multi‐Center Trial of ¹²⁹Xe Gas Exchange MRI and MRS to Evaluate Longitudinal Progression of COPD. Journal of Magnetic Resonance Imaging.
• Pilgrim‐Morris JH, Collier GJ, Takigawa M, Strickland S, Thompson R, Norquay G, Stewart NJ & Wild JM () Mapping the amplitude and phase of dissolved ¹²⁹Xe red blood cell signal oscillations with keyhole spectroscopic lung imaging. Magnetic Resonance in Medicine.
• Pilgrim-Morris JH, Smith LJ, Marshall H, Tahir BA, Collier GJ, Stewart NJ & Wild JM () A framework for modelling whole-lung and regional TL_COusing hyperpolarised¹²⁹Xe lung MRI. ERJ Open Research, 00442-2024.
• Stewart NJ, de Arcos J, Biancardi AM, Collier GJ, Smith LJ, Norquay G, Marshall H, Brau ACS, Lebel RM & Wild JM () Improving Xenon‐129 lung ventilation image SNR with deep‐learning based image reconstruction. Magnetic Resonance in Medicine.
• Collier GJ, Smith LJ, Saunders LC, Swift AJ, Marshall H, Stewart NJ, Norquay G, Hughes PJC, Thomspson AAR & Wild JM () Age, sex, and lung volume dependence of dissolved xenon‐129 MRI gas exchange metrics. Magnetic Resonance in Medicine.
• Vaeggemose M, Schulte RF, Hansen ESS, Miller JJ, Rasmussen CW, Pilgrim-Morris JH, Stewart NJ, Collier GJ, Wild JM & Laustsen C () A Framework for Predicting X-Nuclei Transmitter Gain Using 1H Signal. Tomography, 9(5), 1603-1616.
• Wild JM, Gleeson FV, Svenningsen S, Grist JT, Saunders LC, Collier GJ, Sharma M, Tcherner S, Mozaffaripour A, Matheson AM & Parraga G () Review of Hyperpolarized Pulmonary Functional ¹²⁹Xe MR for Long‐COVID. Journal of Magnetic Resonance Imaging.
• Eaden JA, Weatherley ND, Chan H-F, Collier G, Norquay G, Swift AJ, Rajaram S, Smith LJ, Bartholmai BJ, Bianchi SM & Wild JM () Hyperpolarised 129-Xenon Diffusion-weighted MRI for Assessing Lung Microstructure in IPF. ERJ Open Research, 00048-2023.
• Stewart I, Jacob J, George PM, Molyneaux PL, Porter JC, Allen RJ, Aslani S, Baillie JK, Barratt SL, Beirne P , Bianchi SM et al () Residual Lung Abnormalities Following COVID-19 Hospitalization: Interim Analysis of the UKILD Post-COVID Study. American Journal of Respiratory and Critical Care Medicine.
• Astley JR, Biancardi AM, Marshall H, Hughes PJC, Collier GJ, Smith LJ, Eaden JA, Hughes R, Wild JM & Tahir BA () A Dual‐Channel Deep Learning Approach for Lung Cavity Estimation From Hyperpolarized Gas and Proton MRI. Journal of Magnetic Resonance Imaging.
• Marshall H, Voskrebenzev A, Smith LJ, Biancardi AM, Kern AL, Collier GJ, Wielopolski PA, Ciet P, Tiddens HAWM, Vogel‐Claussen J & Wild JM () ¹²⁹ Xe and Free‐Breathing ¹ H Ventilation MRI in Patients With Cystic Fibrosis: A Dual‐Center Study. Journal of Magnetic Resonance Imaging.
• Wild JM & Collier G () ¹²⁹Xe Pulmonary MRI for Individuals with Post-Acute COVID-19 Syndrome. Radiology.
• Stewart NJ, Smith LJ, Chan H-F, Eaden JA, Rajaram S, Swift AJ, Weatherley ND, Biancardi A, Collier GJ, Hughes D , Klafkowski G et al () Lung MRI with hyperpolarised gases: current & future clinical perspectives. The British Journal of Radiology, 20210207-20210207.
• Grist JT, Chen M, Collier GJ, Raman B, AbuEid G, McIntyre A, Matthews V, Fraser E, Ho L-P, Wild JM & Gleeson F () Hyperpolarized 129Xe MRI Abnormalities in Dyspneic Participants 3 Months after COVID-19 Pneumonia: Preliminary Results. Radiology, 210033-210033.
• Whitfield CA, Latimer P, Horsley A, Wild JM, Collier GJ & Jensen OE () Spectral graph theory efficiently characterises ventilation heterogeneity in lung airway networks.
• Puddu C, Rao M, Xu X, Deppe MH, Collier G, Maunder A, Chan H, De Zanche N, Robb F & Wild JM () An asymmetrical whole‐body birdcage RF coil without RF shield for hyperpolarized 129 Xe lung MR imaging at 1.5 T. Magnetic Resonance in Medicine.
• Mussell G, Marshall H, Smith L, Biancardi A, Hughes P, Capener D, Bray J, Swift A, Rajaram S, Condliffe A , Collier G et al () Xenon ventilation MRI in difficult asthma; initial experience in a clinical setting. European Respiratory Journal.

Chapters

• Albert MS, Altes TA, Anthony D, Barlow MJ, Bueno J, Chekmenev EY, Clapp J, Coffey AM, Collier GJ, Couch MJ , de Lange EE et al (2017) List of Contributors, Hyperpolarized and Inert Gas MRI (pp. xi-xii). Elsevier
• Wild JM, Horn FC, Collier GJ & Marshall H (2017) Dynamic Imaging of Lung Ventilation and Gas Flow With Hyperpolarized Gas MRI, Hyperpolarized and Inert Gas MRI (pp. 47-59). Elsevier

Conference proceedings papers

• Fraser E, Ng K, Saunders L, Grist J, Collier G, Strickland S, Gustafsson L, Smith L, Evans R, Vuddamalay N , Rodgers J et al (2024) HypErpolarised Xenon Magnetic Resonance PuLmonary Imaging in PAtIeNts with Long-COVID (EXPLAIN): Lung diffusion findings. Imaging (pp PA5250-PA5250)
• Saunders L, Hughes PJC, Ng KL, Collier GJ, Grist J, Smith LJ, Strickland S, Gustafsson L, Horsley A, Swift AJ , Fraser E et al (2024) Contrast enhanced MRI does not detect differences in pulmonary perfusion between patients with long COVID and controls. Imaging (pp PA5252-PA5252)
• Smith L, Marshall H, Jakymelen D, Biancardi A, Collier G, Chan H-F, Hughes P, Brook M, Astley J, Munro R , Rajaram S et al (2024) The sensitivity of different lung function metrics to detect airways disease. Respiratory function technologists/scientists (pp OA4590-OA4590)
• Schofield L, Biancardi A, Smith L, Marshall H, Hughes D, Capener D, Bray J, Fazal S, Zalewska A, Collier G , Norquay G et al (2024) 129Xe-MRI to assess regional airway clearance in children with primary ciliary dyskinesia. Paediatric respiratory physiology and sleep (pp OA4664-OA4664)
• Saunders L, Collier G, Smith L, Marshall H, Biancardi A, Swift A, Jakymelen D, Strickland S, Gustafsson L, Munro R , Stewart N et al (2024) 129Xe lung ventilation imaging in patients with long COVID without prior respiratory disease. Imaging (pp PA5251-PA5251)
• Saunders LC, Collier GJ, Smith LJ, Hughes PJC, Marshall H, Chan HF, Biancardi A, Grist J, Strickland S, Gustafsson L , Ho LP et al (2023) S19 Gas exchange imaging using dissolved-phase 129Xe MRI in post COVID cohorts. ‘Shake it off’ – Recovery from COVID-19
• Marshall H, Smith LJ, Biancardi A, Collier GJ, Chan HF, Capener D, Bray J, Jakymelen D, Saunders L, Astley J , Tahir BA et al (2023) P177 129Xe MRI phenotyping and longitudinal change in patients with asthma and/or COPD and normal pulmonary function tests. ‘You ain’t seen nothing yet’ – Imaging across COPD, nodules and lung cancer screening
• Smith LJ, Marshall H, Biancardi A, Collier GJ, Chan HF, Capener D, Bray J, Jakymelen D, Saunders L, Astley J , Tahir BA et al (2023) P176 Bronchodilator response discordance in patients with asthma and/or COPD assessed by 129Xe-MRI and spirometry. ‘You ain’t seen nothing yet’ – Imaging across COPD, nodules and lung cancer screening
• Smith L, Marshall H, Biancardi A, Collier G, Chan H-F, Capener D, Bray J, Jakymelen D, Saunders L, Astley J , Tahir B et al (2023) Xe-MRI bronchodilator response to assess disease severity in patients with asthma and/or COPD. Respiratory function technologists/scientists
• Smith L, Marshall H, Biancardi A, Collier G, Chan H-F, Capener D, Bray J, Jakymelen D, Saunders L, Astley J , Tahir B et al (2023) Bronchodilator response discordance in patients with asthma and/or COPD using Xe-MRI and spirometry. Respiratory function technologists/scientists
• Marshall H, Smith L, Biancardi A, Collier G, Chan H-F, Capener D, Bray J, Jakymelen D, Saunders L, Astley J , Tahir B et al (2023) Longitudinal change in lung physiology and 129Xe MRI over 1 year in patients with asthma and/or COPD. Clinical respiratory physiology, exercise and functional imaging
• Collier G, Saunders L, Smith LJ, Ng K, Grist J, Swift AJ, Davies H, Horsley A, Thompson AAR, Fraser E , Gleeson F et al (2023) Age, sex and lung volume dependence of 129Xe MRI gas exchange metrics. Clinical respiratory physiology, exercise and functional imaging
• Ng K, Grist J, Saunders L, Collier G, Laws A, Abu Eid G, Kainth N, Strickland S, Gustafsson L, Thomas S , Dryhurst-Pearce L et al (2023) Unexplained lung function differences in dyspnoeic non-hospitalised Long-COVID (NHLC) patients and asymptomatic fully recovered COVID-19 controls - the EXPLAIN study. Clinical respiratory physiology, exercise and functional imaging
• Bell LC, Fernandez Coimbra A, Zou Y, Dimond C, Mata J, Muglar J, Shim YM, Mummy D, Driehuys B, Huang Y-C , Niedbalski P et al (2023) Multisite implementation of 129Xe-MRI assessment of COPD disease progression: XeCITE early results. Imaging
• Smith L, Marshall H, Jakymelen D, Biancardi A, Collier GJ, Chan H, Hughes PJC, Brook ML, Astley J, Munro R , Rajaram S et al (2022) Physiological assessment of patients with airways dysanapsis using 129Xe MRI. 09.01 - Respiratory function technologists/scientists
• Marshall H, Smith LJ, Biancardi A, Collier GJ, Chan HF, Hughes PJC, Brook ML, Astley J, Munro R, Rajaram S , Swift AJ et al (2022) Physiological Phenotypes of Patients with Asthma and/or COPD Using 129Xe MRI. A99. LOOK AT THAT! NEW FINDINGS FROM LUNG IMAGING (pp a2175-a2175)
• Marshall H, Smith L, Biancardi A, Collier G, Chan H-F, Hughes P, Astley J, Munro R, Rajaram S, Capener D , Bray J et al (2021) A comparison of 129Xe MRI and advanced lung function testing in patients with asthma and /or COPD: The NOVELTY ADPro substudy. Imaging
• Eaden JA, Collier GJ, Norquay G, Chan H-F, Hughes PJC, Weatherley ND, Rajaram S, Swift A, Leonard CT, Skeoch S , Chaudhuri N et al (2021) S75 Hyperpolarised 129-xenon MRI in differentiating between fibrotic and inflammatory interstitial lung disease and assessing longitudinal change. Basic science in ILD: what drives progression?
• Astley J, Biancardi A, Hughes P, Smith L, Marshall H, Eaden J, Bray J, Weatherley N, Collier G, Wild J & Tahir B (2020) 3D deep convolutional neural network-based ventilated lung segmentation using multi-nuclear hyperpolarized gas MRI. Thoracic Image Analysis, Vol. 12502 (pp 24-35). Lima, Peru, 8 October 2020 - 8 October 2020. View this article in WRRO
• Chan H-F, Petersson Sjögren M, Hughes P, Rodgers O, Collier G, Norquay G, Olsson L, Wollmer P, Wild J & Löndahl J (2020) Benchmarking inhaled nanoparticle measurements of airspace dimension with hyperpolarised 129Xe diffusion-weighted MRI. Imaging
• Whitfield C, Smith L, Jensen O, West N, Wildman M, Collier G, Wild J & Horsley A (2020) Interpretation of multiple breath washout (MBW) measurements of lung function using mathematical modelling and hyperpolarised 3He gas MRI. Respiratory infections
• Smith L, Hughes D, Chan H-F, Johnson K, Bray J, Rodgers O, Collier G, Norquay G, Biancardi A, Hughes P , Kotecha S et al (2019) 1H and 129Xe MRI to detect functional and structural lung disease in sub-clinical cystic fibrosis. Cystic fibrosis
• Smith L, Collier G, Marshall H, Hughes P, Biancardi A, Norquay G, Bray J, Rodgers O, Wildman M, West N , Horsley A et al (2019) Clinical applicability of 3He and 129Xe ventilation MRI in cystic fibrosis: longitudinal follow up. Cystic fibrosis
• Wild JM, Biancardi A, Chan H-F, Smith L, Bray J, Marshall H, Collier G, Norquay G, Hughes P, Swift A , Cousins M et al (2019) Imaging functional and microstructural changes in the lungs of children born prematurely. Imaging
• Eaden J, Hughes P, Collier G, Norquay G, Weatherly N, Austin M, Smith L, Lithgow J, Swift A, Renshaw S , Buch M et al (2019) Longitudinal change in hyperpolarised 129-xenon MR spectroscopy in interstitial lung disease. Imaging
• Mussell G, Marshall H, Smith L, Biancardi A, Hughes P, Swift A, Collier G, Wild J & Sabroe I (2019) Correlations of ventilation heterogeneity and spirometry in asthma; initial experience with hyperpolarised gas MRI in a clinical setting. Imaging
• Whitfield C, Horsley A, Jensen O, Horn F, Smith L, Collier G & Wild J (2019) Predicting multiple breath washout outcomes from hyperpolarised gas magnetic resonance imaging (MRI). Imaging
• Smith L, Collier G, Marshall H, Hughes P, Biancardi A, Norquay G, Bray J, Rodgers O, Wildman M, West N , Horsley A et al (2019) P213 A comparison of ventilation MRI using hyperpolarised 3He and 129Xe to assess cystic fibrosis lung disease. Journal of Cystic Fibrosis, Vol. 18 (pp S117-S117)
• Smith L, Marshall H, Norquay G, Collier G, Rodgers O, Hughes P, Biancardi A, West N, Wildman M, Horsley A & Wild J (2019) P211 129Xe ventilation MRI and LCI to assess acute maximal exercise as a method of airway clearance. Journal of Cystic Fibrosis, Vol. 18 (pp S116-S117)
• Smith L, Collier G, Marshall H, Hughes P, Biancardi A, Norquay G, Bray J, Rodgers O, Wildman M, West N , Horsley A et al (2019) P212 Ventilation MRI tracks longitudinal lung function changes in patients with cystic fibrosis and clinically stable FEV1 and Lung Clearance Index. Journal of Cystic Fibrosis, Vol. 18 (pp S117-S117)
• Smith L, Hughes D, Chan H-F, Johnson K, Bray J, Rodgers O, Collier G, Norquay G, Biancardi A, Hughes P , Kotecha S et al (2019) WS17-2 The sensitivity of MRI to detect both functional and structural lung abnormalities in sub-clinical cystic fibrosis. Journal of Cystic Fibrosis, Vol. 18 (pp S32-S32)
• Weatherley ND, Stewart NJ, Chan HF, Hughes PJC, Marshall H, Austin M, Smith L, Collier G, Rao M, Norquay G , Renshaw SA et al (2018) Probing diffusion and perfusion in idiopathic pulmonary fibrosis with hyperpolarised xenon and dynamic contrast-enhanced magnetic resonance imaging. Thorax, Vol. 73(Suppl 4) (pp A44-A45). London, UK, 5 December 2018 - 7 December 2018. View this article in WRRO
• Smith L, Collier G, Marshall H, Hughes P, Bray J, Rodgers O, Aldag I, West N, Wildman M, Horsley A & Wild J (2018) The effect of inhaled lung volume on ventilation heterogeneity in CF using 3He MRI. Cystic fibrosis
• Tahir B, Hughes P, Robinson S, Marshall H, Stewart N, Biancardi A, Chan HF, Collier G, Hart K, Swinscoe J , Hatton M et al (2018) OC-0182: A comparison of CT ventilation with 3He and 129Xe MRI for functional avoidance treatment planning. Radiotherapy and Oncology, Vol. 127(Supplement 1) (pp S96-S97). Barcelona, Spain, 20 April 2018 - 24 April 2018. View this article in WRRO
• West N, Smith L, Chan H-F, Horn F, Chetcuti P, Moya E, Marshall H, Wild J, Norquay G, Collier G & Rao M (2017) Hyperpolarised gas ventilation MRI detects early lung ventilation heterogeneity in children with primary ciliary dyskinesia. Paediatric Respiratory Physiology and Sleep
• Weatherley N, Chan H-F, Stewart N, Norquay G, Rao M, Collier G, Austin M, Smith L, Marshall H, Renshaw SA , Bianchi S et al (2017) Late breaking abstract - Hyperpolarised gas MRI demonstrates sub-clinical progression in IPF over 6 months. European Respiratory Journal, Vol. 50(Suppl 61). Milan, Italy, 9 September 2017 - 13 September 2017. View this article in WRRO
• Hughes P, Smith L, Horn F, Biancardi A, Collier G, Stewart N, Norquay G, Rao M, Aldag I, Taylor C , Marshall H et al (2017) Ventilation heterogeneity assessed in patients with mild cystic fibrosis and asthma using Hyperpolarised gas MRI histogram analysis. Imaging
• Chan H-F, Collier G, Smith L, Marshall H, Hughes P, Parra-Robles J, Horn F, Norquay G, Stewart N, Taylor C , Aldag I et al (2017) Longitudinal monitoring of lung microstructure with HP gas diffusion-weighted MRI in mild cystic fibrosis children. Cystic Fibrosis View this article in WRRO
• Horn F, Collier G, Chan H-F, Stewart N & Wild J (2016) Regional phase III slope measurement using hyperpolarized gas MR imaging. 1.3 Imaging View this article in WRRO
• Weatherley N, Chan F, Stewart N, Saunders L, Collier G, Norquay G, Rao M, Austin M, Bianchi S & Wild J (2016) Diffusion-weighted hyperpolarised gas MRI in idiopathic pulmonary fibrosis : reproducibility and clinical significance. ERS International Congress 2016 abstracts, Vol. 48(Suppl 60). London, UK, 3 September 2016 - 7 September 2016. View this article in WRRO
• Smith L, Aldag I, Hughes P, Horn F, Marshall H, Norquay G, Collier G, Hughes D, Taylor C, Horsley A & Wild J (2016) Longitudinal monitoring of disease progression in children with mild CF using hyperpolarised gas MRI and LCI. 9.1 Respiratory Function Technologists/Scientists View this article in WRRO
• Smith L, Horn F, Marshall H, Collier G, Hughes P, Aldag I, Taylor C, Horsley A & Wild J (2016) Comparison of phase III slope analysis from MBW with hyperpolarised gas MRI in children with mild CF. 9.1 Respiratory Function Technologists/Scientists
• Tahir B, Marshall H, Hughes P, Stewart N, Horn F, Collier G, Norquay G, Hart K, Swinscoe J, Hatton M , Wild J et al (2016) Ventilation CT : voxel-level comparison with HP gas MRI. European Respiratory Journal, Vol. 48(Suppl 60). Estoril, Portugal, 10 March 2016 - 13 March 2016. View this article in WRRO
• Stewart N, Chan H-F, Hughes P, Collier G, Horn F, Norquay G, Parra-Robles J, Yates D, Collini P, Lawson R , Marshall H et al (2016) Comparison of 3 He and 129 Xe MRI for evaluation of lung microstructure and ventilation at 1.5 T. European Respiratory Journal, Vol. 48(suppl 60), 3 September 2016 - 7 September 2016. View this article in WRRO
• Tahir B, Marshall H, Hughes P, Stewart N, Horn F, Collier G, Norquay G, Hart K, Swinscoe J, Hatton M , Wild J et al (2016) WE-AB-202-07: Ventilation CT: Voxel-Level Comparison with Hyperpolarized Helium-3 & Xenon-129 MRI. Medical Physics, Vol. 43(6) (pp 3795-3796), 31 July 2016 - 4 August 2016. View this article in WRRO
• Aldag I, Marshall H, Taylor C, Horsley A, Hughes D, Smith L, Horn F, Swift A, Parra-Robles J, Hughes P , Collier G et al (2016) WS15.2 Multiple breath washout and imaging with 3 He MRI and CT scans to monitor early-stage lung disease in patients with cystic fibrosis. Journal of Cystic Fibrosis, Vol. 15 (pp S24-S25)
• Wild JM, Collier G, Marshall H, Smith L, Norquay G, Swift AJ, Horn FC, Chan F, Stewart NJ, Hutchison LC , Rao M et al (2015) P283 Hyperpolarised Gas MRI – a pathway to Clinical Diagnostic Imaging. Thorax, Vol. 70(Suppl 3) (pp A220.3-A221)
• Weatherley ND, Stewart NJ, Marshall H, Collier G, Hart K, Horn F, Norquay G, Whyte MK, Bianchi S & Wild JM (2015) P286 Correlations of functional multi-nuclear MR imaging indices with pulmonary function tests in the assessment of idiopathic pulmonary fibrosis. Thorax, Vol. 70(Suppl 3) (pp A223.1-A223)
• Wild J, Smith L, Horn F, Collier G, Swift A, Stewart N, Rao M, Norquay G, Hughes D, Ugonna K & Marshall H (2015) Hyperpolarised gas MR lung imaging – Breaks through to clinical practice. 1.3 Imaging
• Saunders L, Collier G, Smith L, Marshall H, Biancardi A, Jakymelen D, Strickland S, Gustafsson L, Munro R, Rodgers O , Stewart N et al () 129Xe lung ventilation imaging in patients with long COVID without prior respiratory disease. ISMRM Annual Meeting, 4 May 2024 - 9 May 2024.
• Vaeggemose M, Kristensen M, Schulte R, Redda M, Hansen E, Hansen J, Rodgers O, Collier G, Norquay G, Andersen A , Wild J et al () Hyperoxic challenge combined with hyperpolarized 129-xenon dissolved-phase imaging in a porcine model of pulmonary embolism. ISMRM Annual Meeting, 4 May 2024 - 9 May 2024.
• Wolfsohn M, Anya N, Collier G, Dashnaw S, Munro R, Norquay G, Prince M, Rodgers O, Schulte R, Shen W , Wild J et al () The Successful Use of Unenriched Xenon in Dissolved Gas MRI: A Case Report. ISMRM Annual Meeting, 4 May 2024 - 9 May 2024.
• Marshall H, Collier G, Smith L, Chan H-F, Hughes P, Capener D, Bray J, Joseph S, Munro R, Rodgers O , Ball J et al () 129Xe gas transfer lung MRI before and after bronchodilator inhalation in patients with asthma and/or COPD. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
• Collier G, Chan H-F, Norquay G, Stewart N, Munro R, Rodgers O, Schulte R & Wild J () Implementation of dissolved 129Xe lung MRI with 4-echo 3D radial spectroscopic imaging at 3T: comparing with results at 1.5T in healthy volunteers. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
• Hughes P, Marshall H, Smith L, Jakymelen D, Biancardi A, Collier G, Chan H-F, Brook M, Astley J, Munro R , Rajaram S et al () Differentiating patients with asthma and/or chronic obstructive pulmonary disease using lung T1 and M0. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
• Vaeggemose M, Norquay G, Hansen E, Stewart N, Rodgers O, Munro R, Schulte R, Collier G, Laustsen C & Wild J () Batch-mode production of hyperpolarised xenon gas with a continuous-flow polariser for preclinical and clinical human lung ventilation images. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
• Stewart N, de Arcos J, Biancardi A, Pilgrim-Morris J, Rodgers O, Munro R, Collier G, Norquay G, Marshall H, Brau A , Lebel M et al () Improving Xenon-129 Lung Ventilation Image Quality with a Commercial Deep-Learning Based Image Reconstruction. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
• Pilgrim-Morris J, Smith L, Astley J, Saunders L, Collier G, Biancardi A, Tahir B, Marshall H, Hardaker L, Fihn-Wikander T , Hughes R et al () Modelling Whole-Lung and Regional Carbon Monoxide Transfer Factor with Hyperpolarized 129Xe MRI in Asthma and COPD Patients. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
• Marshall H, Collier G, Chan H-F, Smith L, Hughes P, Capener D, Bray J, Joseph S, Munro R, Rodgers O , Ball J et al () Longitudinal 129Xe MRI assessment of lung gas transfer and microstructure over 1 year in patients with asthma and/or COPD. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
• Collier G, Chan H-F, Stewart N, Norquay G, Smith L, Rao M, Marshall H, Schulte R & Wild J () Age and lung volume dependence of dissolved xenon-129 imaging parameters. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
• Norquay G, Collier G, Schulte R & Wild J () 129Xe chemical shift mapping in the lungs with 3D density-weighted MRSI. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
• Chan H-F, Collier G, Smith L, Biancardi A, Bray J, Marshall H, Hughes P, Rao M, Norquay G, Swift A , Hart K et al () Dissolved 129Xe spectroscopy in the lungs of preterm-born children. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
• Astley J, Biancardi A, Marshall H, Tofan M-M, Smith L, Hughes P, Collier G, Hatton M, Blé F-X, Hughes R , Wild J et al () Deep learning-based synthesis of hyperpolarized gas MRI ventilation from 3D multi-inflation proton MRI. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
• Astley J, Biancardi A, Marshall H, Hughes P, Collier G, Smith L, Eaden J, Blé F-X, Hughes R, Wild J & Tahir B () A multi-channel deep learning approach for lung cavity estimation from hyperpolarized gas and proton MRI. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.

Other

• (2016) Commentaries on Viewpoint: Could lobar flow sequencing account for convection-dependent ventilation heterogeneity in normal humans?. Journal of Applied Physiology, 121(2), 592-592. View this article in WRRO

Preprints

• Grist JT, Collier GJ, Walters H, Chen M, Eid GA, Laws A, Matthews V, Jacob K, Cross S, Eves A , Durant M et al () The Investigation of Pulmonary Abnormalities using Hyperpolarised Xenon Magnetic Resonance Imaging in Patients with Long-COVID, Cold Spring Harbor Laboratory.
• Whitfield CA, Horsley A, Jensen OE, Horn FC, Collier GJ, Smith LJ & Wild JM () Model-based Bayesian inference of the ventilation distribution in patients with Cystic Fibrosis from multiple breath washout, with comparison to ventilation MRI, Cold Spring Harbor Laboratory.
• Saunders LC, Collier GJ, Chan H-F, Hughes PJC, Smith LJ, Watson J, Meiring J, Gabriel Z, Newman T, Plowright M , Eaden JA et al () Longitudinal lung function assessment of patients hospitalised with COVID-19 using ¹H and ¹²⁹Xe lung MRI, Cold Spring Harbor Laboratory.