Dr Natalie Barratt

School of Medicine and Population Health

Postdoctoral Research Associate

n.barratt@sheffield.ac.uk
+44 114 215 9579

Room LU112, L Floor, Royal Hallamshire Hospital

Full contact details

Dr Natalie Barratt
School of Medicine and Population Health
Room LU112, L Floor
Royal Hallamshire Hospital
Glossop Road
Sheffield
S10 2JF

Profile

Dr Natalie Barratt joined the Clinical Infection Research Group in July 2022. She is currently investigating human serum and mucosal humoral immune responses to pathogens of global health importance, particularly SARS-CoV-2, in clinical vaccine trials and cohort studies. She is a microbiologist with expertise in bacterial virulence mechanisms, microbiomics and bacterial molecular genetics.

Previously, Natalie was a PDRA at the Institute for Sustainable Food where her research focused on soil microbiota and plant-microbe interactions in the context of sustainable, low input agriculture (from 2021). Before this Natalie was a PDRA at The University of Leicester working on a BBSRC Newton Fund Project: “Rapid diagnostics and control strategies for enteric bacterial pathogens in backyard and commercial poultry production in Thailand and the Philippines” (from 2018). She gained her PhD in Molecular Microbiology in 2018 from The University of Nottingham.

Publications

Journal articles

Jagne YJ, Jobe D, Darboe A, Danso M, Barratt N, Gomez M, Wenlock R, Jarju S, Sylva EL, Touray AF , Toure F et al (2025) Compartmentalised mucosal and blood immunity to SARS-CoV-2 is associated with high seroprevalence before the Delta wave in Africa. Communications Medicine, 5(1). View this article in WRRO
Colton H, Barratt N, Temperton N, Hornsby H, Angyal A, Grouneva I, Lindsey BB, Kearns P, Barnes E, Goodyear CS , Richter A et al (2024) Greater preservation of SARS‐CoV‐2 neutralising antibody responses following the ChAdOx1‐S (AZD1222) vaccine compared with mRNA vaccines in haematopoietic cell transplant recipients. British Journal of Haematology, 205(6), 2206-2218. View this article in WRRO
Hornsby H, Nicols AR, Longet S, Liu C, Tomic A, Angyal A, Kronsteiner B, Tyerman JK, Tipton T, Zhang P , Gallis M et al (2023) Omicron infection following vaccination enhances a broad spectrum of immune responses dependent on infection history. Nature Communications, 14(1). View this article in WRRO
Al‐Gallas N, Belghouthi K, Barratt NA, Ghedira K, Hotzel H, Tomaso H, El‐Adawy H, Neubauer H, Laouini D, Zarrouk S , Abbassi MS et al (2022) Identification and characterization of multidrug‐resistant ESBL‐producing Salmonella enterica serovars Kentucky and Typhimurium isolated in Tunisia CTX‐M‐61/TEM‐34, a novel cefotaxime‐hydrolysing β‐lactamase of Salmonella. Journal of Applied Microbiology, 132(1), 279-289.
Cayrou C, Barratt NA, Ketley JM & Bayliss CD () Phase Variation During Host Colonization and Invasion by Campylobacter jejuni and Other Campylobacter Species. Frontiers in Microbiology, 12.

Preprints

Hornsby H, Nicols AR, Longet S, Liu C, Tomic A, Angyal A, Kronsteiner B, Tyerman JK, Tipton T, Zhang P , Ramalho MG et al (2023) Omicron BA.1/BA.2 infections in triple-vaccinated individuals enhance a diverse repertoire of mucosal and blood immune responses, Cold Spring Harbor Laboratory.