Professor Sarah Rowland-Jones

B.M. B.Ch., M.A. (Cantab), D.M. (Oxon), FRCP, F.Med.Sci.

Department of Infection, Immunity and Cardiovascular Disease

Florey Professor of Infection and Immunity

s.l.rowland-jones@sheffield.ac.uk
+44 114 215 9608

+44 114 271 1863 (Fax)

The Medical School

Full contact details

Professor Sarah Rowland-Jones
Department of Infection, Immunity and Cardiovascular Disease
The Medical School
Beech Hill Road
Sheffield
S10 2RX

Profile

For enquiries, please contact – iicd-operational@sheffield.ac.uk

I trained in medicine in Cambridge and Oxford Universities, then did post-graduate training in medicine in London and Sheffield before completing specialist training in Infectious Diseases in Oxford.

I became interested in HIV infection as a junior doctor in London, looking after some of the first AIDS patients to be diagnosed in the UK. I started my research career with a doctorate in the Weatherall Institute of Molecular Oxford supervised by Professor Andrew McMichael, studying the role of HIV-specific cytotoxic T lymphocytes (CTL) in the outcomes of HIV-1 infection and exposure.

My research has been supported by a series of MRC Clinical research fellowships (Training, Clinician Scientist, Senior), culminating in the award of an MRC Clinical Research Professorship from 2008 to 2014.

I became increasingly interested in working in the tropics and was fortunate to have the opportunity to collaborate in studies of cellular immune responses to viral infections with researchers in places such as The Gambia, Kenya, Thailand, Viet Nam and China. This led to me becoming Director of the Oxford Centre for Tropical Medicine between 2001 and 2004, and then moving to West Africa to become Research Director of the MRC Laboratories, The Gambia, the UK’s oldest and largest tropical research unit between 2004 and 2008. Whilst in The Gambia my research interests focused on HIV-2 pathogenesis and the development of infant immunity in response to pathogens and vaccines in early life.

I joined the IICD department in 2018 as Florey Professor of Infection and Immunity, and now divide my time between Sheffield and Oxford. I remain an active clinician, holding an Honorary Consultant contract in adult Infectious Diseases. I was President of the Royal Society of Tropical Medicine and Hygiene between 2018 and 2019 after six years as a Trustee of the Society, and am also a Fellow of Christ Church, Oxford.

Research interests

My research interests focus on host-pathogen interactions in viral infections, with a particular interest in HIV infection and how CMV co-infection contributes to pathogenesis in both HIV-infected people and uninfected infants born to HIV-infected women.

I collaborate closely with Professor Rashida Ferrand (LSHTM) in Harare, Zimbabwe, in studies of HIV pathogenesis and immunology in older children and adolescents with perinatally-acquired HIV infection (PHIV).

In Sheffield I co-lead a research group with Dr Thushan de Silva, where I am working on projects to evaluate vaccine-induced immunity in older children with PHIV, and to characterise acquisition of viral immunity in patients who have undergone Haemapoietic Stem Cell Transplantation (HSCT).

Current projects

How does the immune system reconstitute cellular responses (T-cells and NK cells) to persistent virus infection following HSCT.
What levels of antibody responses to routine childhood vaccines given as part of the Expanded Programme of Immunisation persist in children who present late with PHIV? Are booster immunisations required in this age-group?

Publications

Show: Featured publications All publications

Featured publications

Journal articles

Hirao K, Andrews S, Kuroki K, Kusaka H, Tadokoro T, Kita S, Ose T, Rowland-Jones SL & Maenaka K (2020) Structure of HIV-2 Nef Reveals Features Distinct from HIV-1 Involved in Immune Regulation. iScience, 23(1).
Yindom L-M, Simms V, Majonga ED, McHugh G, Dauya E, Bandason T, Vincon H, Rylance J, Munyati S, Ferrand RA & Rowland-Jones SL (2019) Unexpectedly High Prevalence of Cytomegalovirus DNAemia in Older Children and Adolescents With Perinatally Acquired Human Immunodeficiency Virus Infection. Clinical Infectious Diseases, 69(4), 580-587.
James KL, de Silva TI, Brown K, Whittle H, Taylor S, McVean G, Esbjörnsson J & Rowland-Jones SL (2018) Low-Bias RNA Sequencing of the HIV-2 Genome from Blood Plasma. Journal of Virology, 93(1). View this article in WRRO
de Silva T, Leligdowicz A, Carlson J, Garcia-Knight M, Onyango C, Miller N, Yindom LM, Hue S, Jaye A, Dong T , Cotten M et al (2018) HLA-associated polymorphisms in the HIV-2 capsid highlight key differences between HIV-1 and HIV-2 immune adaptation. AIDS, 6, 704-709. View this article in WRRO
Jayasooriya S, de Silva TI, Njie-jobe J, Sanyang C, Leese AM, Bell AI, McAulay KA, Yanchun P, Long HM, Dong T , Whittle HC et al (2015) Early Virological and Immunological Events in Asymptomatic Epstein-Barr Virus Infection in African Children. PLOS Pathogens, 11(3). View this article in WRRO
de Silva TI, Peng Y, Leligdowicz A, Zaidi I, Li L, Griffin H, Blais M-E, Vincent T, Saraiva M, Yindom L-M , van Tienen C et al (2013) Correlates of T-cell–mediated viral control and phenotype of CD8+ T cells in HIV-2, a naturally contained human retroviral infection. Blood, 121(21), 4330-4339.
John‐Stewart GC, Mbori‐Ngacha D, Payne BL, Farquhar C, Richardson BA, Emery S, Otieno P, Obimbo E, Dong T, Slyker J , Nduati R et al (2009) HIV‐1–Specific Cytotoxic T Lymphocytes and Breast Milk HIV‐1 Transmission. The Journal of Infectious Diseases, 199(6), 889-898.
Leligdowicz A, Yindom L-M, Onyango C, Sarge-Njie R, Alabi A, Cotten M, Vincent T, da Costa C, Aaby P, Jaye A , Dong T et al (2007) Robust Gag-specific T cell responses characterize viremia control in HIV-2 infection. Journal of Clinical Investigation, 117(10), 3067-3074.
Thananchai H, Gillespie G, Martin MP, Bashirova A, Yawata N, Yawata M, Easterbrook P, McVicar DW, Maenaka K, Parham P , Carrington M et al (2007) Cutting Edge: Allele-Specific and Peptide-Dependent Interactions between KIR3DL1 and HLA-A and HLA-B. The Journal of Immunology, 178(1), 33-37.
Lühn K, Simmons CP, Moran E, Dung NTP, Chau TNB, Quyen NTH, Thao LTT, Van Ngoc T, Dung NM, Wills B , Farrar J et al (2007) Increased frequencies of CD4+CD25high regulatory T cells in acute dengue infection. Journal of Experimental Medicine, 204(5), 979-985.
Dong T, Stewart-Jones G, Chen N, Easterbrook P, Xu X, Papagno L, Appay V, Weekes M, Conlon C, Spina C , Little S et al (2004) HIV-specific Cytotoxic T Cells from Long-Term Survivors Select a Unique T Cell Receptor. Journal of Experimental Medicine, 200(12), 1547-1557.
Kaul R, Dong T, Plummer FA, Kimani J, Rostron T, Kiama P, Njagi E, Irungu E, Farah B, Oyugi J , Chakraborty R et al (2001) CD8+ lymphocytes respond to different HIV epitopes in seronegative and infected subjects. Journal of Clinical Investigation, 107(10), 1303-1310.
Goulder PJR, Phillips RE, Colbert RA, McAdam S, Ogg G, Nowak MA, Giangrande P, Luzzi G, Morgana B, Edwards A , McMichael AJ et al (1997) Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS. Nature Medicine, 3(2), 212-217.
Rowland-Jones S, Sutton J, Ariyoshi K, Dong T, Gotch F, McAdam S, Whitby D, Sabally S, Gallimore A, Corrah T , Takiguchi M et al (1995) HIV-specific cytotoxic T-cells in HIV-exposed but uninfected Gambian women. Nature Medicine, 1(1), 59-64.
Ndure J, Noho-Konteh F, Adetifa JU, Cox M, Barker F, Le MT, Sanyang LC, Drammeh A, Whittle HC, Clarke E , Plebanski M et al () Negative Correlation between Circulating CD4+FOXP3+CD127− Regulatory T Cells and Subsequent Antibody Responses to Infant Measles Vaccine but Not Diphtheria–Tetanus–Pertussis Vaccine Implies a Regulatory Role. Frontiers in Immunology, 8.
Noho-Konteh F, Adetifa JU, Cox M, Hossin S, Reynolds J, Le MT, Sanyang LC, Drammeh A, Plebanski M, Forster T , Dickinson P et al () Sex-Differential Non-Vaccine-Specific Immunological Effects of Diphtheria-Tetanus-Pertussis and Measles Vaccination. Clinical Infectious Diseases, ciw492-ciw492.
Darboe F, Adetifa JU, Reynolds J, Hossin S, Plebanski M, Netea MG, Rowland-Jones SL, Sutherland JS & Flanagan KL () Minimal Sex-Differential Modulation of Reactivity to Pathogens and Toll-Like Receptor Ligands following Infant Bacillus Calmette–Guérin Russia Vaccination. Frontiers in Immunology, 8.

All publications

Books

Gillespie GMA, Appay V, Rowland-Jones SL & McMichael AJ (2002) The use of tetramers in the quantitative analysis of T-cell responses. Elsevier.

Journal articles

Duri K, Chimhuya S, Gomo E, Munjoma PT, Chandiwana P, Yindom LM, Mhandire K, Ziruma A, Mtapuri-Zinyowera S, Mazengera LR , Misselwitz B et al (2021) Role of antenatal plasma cytomegalovirus DNA levels on pregnancy outcome and HIV-1 vertical transmission among mothers in the University of Zimbabwe birth cohort study (UZBCS). Virology Journal, 18(1).
Misra R, Mulligan JK, Rowland-Jones S & Zemlin M (2021) Editorial: Autoimmunity and Chronic Inflammation in Early Life. Frontiers in Immunology, 12.
Colton H, Hodgson D, Hornsby H, Brown R, Mckenzie J, Bradley KL, James C, Lindsey BB, Birch S, Marsh L , Wood S et al (2021) Risk factors for SARS-CoV-2 seroprevalence following the first pandemic wave in UK healthcare workers in a large NHS Foundation Trust. Wellcome Open Research, 6. View this article in WRRO
Boswell MT, Yindom L-M, Hameiri-Bowen D, Mchugh G, Dauya E, Bandason T, Mujuru H, Esbjörnsson J, Ferrand RA & Rowland-Jones S (2021) TRIM22 genotype is not associated with markers of disease progression in children with HIV-1 infection. AIDS, Publish Ahead of Print.
Touizer E, Alrubayyi A, Rees-Spear C, Fisher-Pearson N, Griffith SA, Muir L, Pellegrino P, Waters L, Burns F, Kinloch S , Rowland-Jones S et al (2021) Failure to seroconvert after two doses of BNT162b2 SARS-CoV-2 vaccine in a patient with uncontrolled HIV. The Lancet HIV, 8(6), e317-e318.
Hameiri-Bowen D, Sovershaeva E, Flaegstad T, Gutteberg TJ, Ngwira LG, Simms V, Rehman AM, Mchugh G, Bandason T, Ferrand RA , Rowland-Jones S et al (2021) Soluble biomarkers associated with chronic lung disease in older children and adolescents with perinatal HIV infection. AIDS, Publish Ahead of Print.
Ogbe A, Kronsteiner B, Skelly DT, Pace M, Brown A, Adland E, Adair K, Akhter HD, Ali M, Ali S-E , Angyal A et al (2021) T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses.. Nat Commun, 12(1), 2055.
Hassan AS, Hare J, Gounder K, Nazziwa J, Karlson S, Olsson L, Streatfield C, Kamali A, Karita E, Kilembe W , Price MA et al (2021) A Stronger Innate Immune Response During Hyperacute HIV-1 Infection is associated with ACUTE retroviral syndrome.. Clin Infect Dis.
Gea-Mallorquí E & Rowland-Jones S (2021) Sensing our Z-RNA. Nature Reviews Immunology, 21(2), 71.
Leary S, Gaudieri S, Parker MD, Chopra A, James I, Pakala S, Alves E, John M, Lindsey BB, Keeley AJ , Rowland-Jones SL et al (2021) Generation of a novel sars-cov-2 sub-genomic rna due to the r203k/ g204r variant in nucleocapsid: Homologous recombination has potential to change sars-cov-2 at both protein and rna level. Pathogens and Immunity, 6(2), 27-49.
Groves DC, Rowland-Jones SL & Angyal A (2020) The D614G mutations in the SARS-CoV-2 spike protein: Implications for viral infectivity, disease severity and vaccine design. Biochemical and Biophysical Research Communications.
Yengo CK, Torimiro J, Kowo M, Lebon PA, Tiedeu BA, Luma H, Njoya O, Rowland-Jones S & Yindom L-M (2020) Variation of HLA class I (-A and -C) genes in individuals infected with hepatitis B or hepatitis C virus in Cameroon. Heliyon, 6(10), e05232-e05232.
Ellis PK, Shackley F, Ugonna K, Ryan CE, Hughes D, Owens S, Brown P, Riordan A, Ilozue CI, Rowland-Jones SL & Collini PJ (2020) Chronic lung disease in patients with perinatally acquired HIV in England: a retrospective case-note review. Pediatric Infectious Disease Journal. View this article in WRRO
Korber B, Fischer WM, Gnanakaran S, Yoon H, Theiler J, Abfalterer W, Hengartner N, Giorgi EE, Bhattacharya T, Foley B , Hastie KM et al (2020) Tracking changes in SARS-CoV-2 Spike: evidence that D614G increases infectivity of the COVID-19 virus. Cell. View this article in WRRO
Bundy D, Burbano C, Lloyd-Evans E, Sorgho G, Lavadenz F, Adam Z, Drake L, Rowland-Jones S & Piot P (2020) A commentary on the interagency symposium: ‘Building a Healthier Future: A Human Capital Perspective on Health and Education’, presented at the European Congress of Tropical Medicine and International Health, Liverpool, UK, October 2019. International Health, 12(4), 235-237.
Frigati LJ, Ameyan W, Cotton MF, Gregson CL, Hoare J, Jao J, Majonga ED, Myer L, Penazzato M, Rukuni R , Rowland-Jones S et al (2020) Chronic comorbidities in children and adolescents with perinatally acquired HIV infection in sub-Saharan Africa in the era of antiretroviral therapy. The Lancet Child & Adolescent Health.
Pul L, Majonga E, Ferrand R, Rowland‐Jones SL & Yindom L (2020) A novel full‐length two‐domain KIR2DL5A allele isolated in Zimbabwean samples: KIR2DL5A*0010104. HLA, 96(1), 135-136.
McHugh G, Rehman AM, Simms V, Gonzalez‐Martinez C, Bandason T, Dauya E, Moyo B, Mujuru H, Rylance J, Sovershaeva E , Weiss HA et al (2020) Chronic lung disease in children and adolescents with HIV: a case–control study. Tropical Medicine & International Health, 25(5), 590-599.
Hirao K, Andrews S, Kuroki K, Kusaka H, Tadokoro T, Kita S, Ose T, Rowland-Jones SL & Maenaka K (2020) Structure of HIV-2 Nef Reveals Features Distinct from HIV-1 Involved in Immune Regulation. iScience, 23(1).
Torimiro J, Yengo CK, Bimela JS, Tiedeu AB, Lebon PA, Sake CS, Kouanfack C, Nchinda G, Rowland-Jones S & Yindom L-M (2020) Killer Cell Immunoglobulin-Like Receptor Genotypes and Haplotypes Contribute to Susceptibility to Hepatitis B Virus and Hepatitis C Virus Infection in Cameroon. OMICS: A Journal of Integrative Biology, 24(2), 110-115.
Esbjörnsson J, Jansson M, Jespersen S, Månsson F, Hønge BL, Lindman J, Medina C, da Silva ZJ, Norrgren H, Medstrand P , Rowland-Jones SL et al (2019) HIV-2 as a model to identify a functional HIV cure. AIDS Research and Therapy, 16(1). View this article in WRRO
Sovershaeva E, Kranzer K, Mchugh G, Bandason T, Majonga ED, Usmani OS, Rowland-Jones S, Gutteberg T, Flægstad T, Ferrand RA & Odland JØ (2019) History of tuberculosis is associated with lower exhaled nitric oxide levels in HIV-infected children. AIDS, 33(11), 1711-1718. View this article in WRRO
Yindom L-M, Simms V, Majonga ED, McHugh G, Dauya E, Bandason T, Vincon H, Rylance J, Munyati S, Ferrand RA & Rowland-Jones SL (2019) Unexpectedly High Prevalence of Cytomegalovirus DNAemia in Older Children and Adolescents With Perinatally Acquired Human Immunodeficiency Virus Infection. Clinical Infectious Diseases, 69(4), 580-587.
Boswell MT, Palm A, Karlson S, Månsson F, Norrgren H, Jansson M, Medstrand P, Rowland-Jones S & Esbjornsson J (2019) A17 The effect of intra-host evolution of HIV-2 capsid on disease progression. Virus Evolution, 5(Supplement_1).
Nabatanzi R, Bayigga L, Cose S, Rowland-Jones S, Canderan G, Joloba M & Nakanjako D (2019) Aberrant natural killer (NK) cell activation and dysfunction among ART-treated HIV-infected adults in an African cohort. Clinical Immunology, 201, 55-60.
Esbjörnsson J, Månsson F, Lindman J, Rowland-Jones SL, Jansson M, Medstrand P & Norrgren H (2019) New insights are game-changers in HIV-2 disease management – Authors' reply. The Lancet HIV, 6(4), e214-e215.
Kaewpreedee P, Boonrat P, Tansiri Y, Rowland-Jones SL & Hansasuta P (2019) Dimorphism in the T-cell receptor constant region affects T-cell function, phenotype and HIV outcome. AIDS, 33(9), 1421-1429.
Rafferty H, Chirro O, Oduor C, Wahome E, Ngoi C, van der Elst E, Berger R, Rowland-Jones S, Graham SM & Sanders EJ (2019) Pilot testing of an online training module about screening for acute HIV infection in adult patients seeking urgent healthcare. International Health, 11(2), 93-100.
Mhandire K, Zijenah LS, Tshabalala M, Yindom L-M, Mlambo T, Mhandire DZ, Musarurwa C, Duri K, Rowland-Jones S, Dandara C & Stray-Pedersen B (2019) KIR and HLA-C Genetic Polymorphisms Influence Plasma IP-10 Concentration in Antiretroviral Therapy-Naive HIV-Infected Adult Zimbabweans. OMICS: A Journal of Integrative Biology, 23(2), 111-118.
Boswell MT & Rowland‐Jones SL (2019) Delayed disease progression in HIV‐2: the importance of TRIM5α and the retroviral capsid. Clinical & Experimental Immunology, 196(3), 305-317.
Esbjörnsson J, Månsson F, Kvist A, da Silva ZJ, Andersson S, Fenyö EM, Isberg P-E, Biague AJ, Lindman J, Palm AA , Rowland-Jones SL et al (2019) Long-term follow-up of HIV-2-related AIDS and mortality in Guinea-Bissau: a prospective open cohort study. The Lancet HIV, 6(1), e25-e31.
James KL, de Silva TI, Brown K, Whittle H, Taylor S, McVean G, Esbjörnsson J & Rowland-Jones SL (2018) Low-Bias RNA Sequencing of the HIV-2 Genome from Blood Plasma. Journal of Virology, 93(1). View this article in WRRO
Andrews SM, Zhang Y, Dong T, Rowland-Jones SL, Gupta S & Esbjörnsson J (2018) Analysis of HIV-1 envelope evolution suggests antibody-mediated selection of common epitopes among Chinese former plasma donors from a narrow-source outbreak. Scientific Reports, 8(1).
Walker-Sperling V, Ramsuran V, Martin M, Naranbhai V, Li H, Anderson SK, Rowland-Jones S, Yindom L-M, Ghebremichael M, Ndung’u T , Walker BD et al (2018) P069UTR SNPS rs111686073 and rs73410010 independently modify expression of tapasin in blacks. Human Immunology, 79, 113-113.
Simms V, Rylance S, Bandason T, Dauya E, Mchugh G, Munyati S, Mujuru H, Rowland-Jones SL, Weiss HA & Ferrand RA (2018) CD4 count recovery following initiation of HIV antiretroviral therapy in older childhood and adolescence. AIDS, 1-1.
de Silva T, Leligdowicz A, Carlson J, Garcia-Knight M, Onyango C, Miller N, Yindom LM, Hue S, Jaye A, Dong T , Cotten M et al (2018) HLA-associated polymorphisms in the HIV-2 capsid highlight key differences between HIV-1 and HIV-2 immune adaptation. AIDS, 6, 704-709. View this article in WRRO
Murakoshi H, Koyanagi M, Akahoshi T, Chikata T, Kuse N, Gatanaga H, Rowland-Jones SL, Oka S & Takiguchi M (2018) Impact of a single HLA-A*24:02-associated escape mutation on the detrimental effect of HLA-B*35:01 in HIV-1 control. EBioMedicine, 36, 103-112.
Gonzalez-Martinez C, Kranzer K, McHugh G, Corbett EL, Mujuru H, Nicol MP, Rowland-Jones S, Rehman AM, Gutteberg TJ, Flaegstad T , Odland JO et al (2017) Azithromycin versus placebo for the treatment of HIV-associated chronic lung disease in children and adolescents (BREATHE trial): study protocol for a randomised controlled trial. Trials, 18(1).
Glanville JM, Moody A-M, Peng Y, Taylor S, Ladell K, Gillespie G, de Bree G, Baban D, Stewart-Jones G, Cullen C , Mead AJ et al (2017) TCR-Identical CD8+ T-Cells Can Have Distinct Killing Efficacy Determined By Events Beyond the T-Cell Receptor. Blood, 130(Suppl_1), 692-692.
Pickering H, Teng A, Faal N, Joof H, Makalo P, Cassama E, Nabicassa M, Last AR, Burr SE, Rowland-Jones SL , Thomson NR et al (2017) Genome-wide profiling of humoral immunity and pathogen genes under selection identifies immune evasion tactics of Chlamydia trachomatis during ocular infection. Scientific Reports, 7(1).
Khatamzas E, Hipp MM, Gaughan D, Pichulik T, Leslie A, Fernandes RA, Muraro D, Booth S, Zausmer K, Sun M , Kessler B et al (2017) Snapin promotes HIV ‐1 transmission from dendritic cells by dampening TLR 8 signaling. The EMBO Journal, 36(20), 2998-3011.
Garcia-Knight MA, Nduati E, Hassan AS, Nkumama I, Etyang TJ, Hajj NJ, Gambo F, Odera D, Berkley JA, Rowland-Jones SL & Urban B (2017) Cytomegalovirus viraemia is associated with poor growth and T-cell activation with an increased burden in HIV-exposed uninfected infants. AIDS, 31(13), 1809-1818.
Hassan AS, Hare J, Kamini G, Yindom LM, Kamali A, Karita E, Kilemba W, Price MA, Borrow P, Bjorkman P , Albert J et al (2017) A35 Viral evolution and innate immune responses during acute HIV-1 infection and their association with disease pathogenesis. Virus Evolution, 3(suppl_1).
Mhandire K, Zijenah LS, Yindom L-M, Duri K, Mlambo T, Tshabalala M, Mazengera LR, Mhandire DZ, Musarurwa C, Dandara C , Rowland-Jones S et al (2016) KIR Gene Content Diversity in a Zimbabwean Population: Does KIR2DL2 Have a Role in Protection Against Human Immunodeficiency Virus Infection?. OMICS: A Journal of Integrative Biology, 20(12), 727-735.
Angin M, Wong G, Papagno L, Versmisse P, David A, Bayard C, Charmeteau-De Muylder B, Besseghir A, Thiébaut R, Boufassa F , Pancino G et al (2016) Preservation of Lymphopoietic Potential and Virus Suppressive Capacity by CD8+ T Cells in HIV-2–Infected Controllers. The Journal of Immunology, 197(7), 2787-2795.
Rylance J, Mchugh G, Metcalfe J, Mujuru H, Nathoo K, Wilmore S, Rowland-Jones S, Majonga E, Kranzer K & Ferrand RA (2016) Chronic lung disease in HIV-infected children established on antiretroviral therapy. AIDS, 30(18), 2795-2803.
Garcia-Knight MA, Slyker J, Payne BL, Pond SLK, de Silva TI, Chohan B, Khasimwa B, Mbori-Ngacha D, John-Stewart G, Rowland-Jones SL & Esbjörnsson J (2016) Viral Evolution and Cytotoxic T Cell Restricted Selection in Acute Infant HIV-1 Infection. Scientific Reports, 6. View this article in WRRO
Shepherd BL, Bandason T, Ferrand R, Rowland-Jones S & Yindom L-M (2016) HLA-C*16:01:01:02, a recently isolated HLA class I allele from Southern Africa. HLA, 87(6), 470-471.
Shepherd BL, Dauya E, Ferrand R, Rowland-Jones S & Yindom L-M (2016) Isolation of full-lengthHLA-C*18:02allele in an individual from Sub-Saharan Africa. HLA, 87(6), 471-472.
Nuvor SV, Whittle H, Rowland-Jones S & Jaye A (2016) Higher Type 1 Interferon Levels in Plasma of Asymptomatic HIV-2 than in HIV-1 Individuals. Advances in Infectious Diseases, 06(01), 15-23.
Shepherd BL, Ferrand R, Rowland-Jones S & Yindom L-M (2016) HLA-C*06:04:02a novel HLA-C allele isolated from donors of Southern African descent. HLA, 87(5), 402-403.
Fish EN, Flanagan KL, Furman D, Klein SL, Kollmann TR, Jeppesen DL, Levy O, Marchant A, Namachivayam S, Netea MG , Plebanski M et al (2016) Changing oral vaccine to inactivated polio vaccine might increase mortality. The Lancet, 387(10023), 1054-1055.
Rowland-Jones SL (2016) Chikungunya: out of the tropical forests and heading our way …. Transactions of The Royal Society of Tropical Medicine and Hygiene, 110(2), 85-86.
Fryer HR, Van Tienen C, Van Der Loeff MS, Aaby P, Da Silva ZJ, Whittle H, Rowland-Jones SL & de Silva TI (2015) Predicting the extinction of HIV-2 in rural Guinea-Bissau. AIDS, 29(18), 2479-2486. View this article in WRRO
Nduati EW, Hassan AS, Knight MG, Muema DM, Jahangir MN, Mwaringa SL, Etyang TJ, Rowland-Jones S, Urban BC & Berkley JA (2015) Outcomes of prevention of mother to child transmission of the human immunodeficiency virus-1 in rural Kenya—a cohort study. BMC Public Health, 15(1).
(2015) Correction. European Journal of Immunology, 45(9), 2701-2701.
Yang KL, Hung JH & Lin PY (2015) A novel HLA allele,HLA-DRB1*15:116, discovered in a Taiwanese unrelated hematopoietic stem cell donor. Tissue Antigens, 86(2), 149-150.
(2015) 8th IAS Conference on HIV Pathogenesis, Treatment & Prevention 19-22 July 2015, Vancouver, Canada. Journal of the International AIDS Society, 18, 20479-20479.
V. Nuvor S, Rowland-Jones S, Whittle H & Jaye A (2015) Differential Expressions of Selected Activating and Inhibitory Receptors on K562-Stimulated Natural Killer (NK) Cells in HIV-1 and HIV-2 Infections. World Journal of AIDS, 05(01), 21-29.
Wang L, Xu K, Dong T, Rowland-Jones SL & Yindom LM (2015) KIR3DS1*0130111: A novel KIR allele identified using molecular typing methods. Tissue Antigens, 85(4), 296-297.
Jayasooriya S, de Silva TI, Njie-jobe J, Sanyang C, Leese AM, Bell AI, McAulay KA, Yanchun P, Long HM, Dong T , Whittle HC et al (2015) Early Virological and Immunological Events in Asymptomatic Epstein-Barr Virus Infection in African Children. PLOS Pathogens, 11(3). View this article in WRRO
Yindom L-M, de Silva TI & Rowland-Jones SL (2015) KIR3DL1*0250102: a novel three-domain KIR subtype identified in West Africa. Tissue Antigens, 85(2), 151-152.
Yindom L-M, de Silva TI & Rowland-Jones SL (2015) Identification of a novel three-domain KIR allele:KIR3DL1*087using high-resolution molecular techniques. Tissue Antigens, 85(2), 153-154.
Wang L, Zhang Y, Dong T, Rowland-Jones SL & Yindom LM (2015) KIR3DS1*0130109: A novel activating three-domain KIR identified using sequence-based typing. Tissue Antigens, 86(3), 222-223.
Wang L, Zhang Y, Dong T, Rowland-Jones SL & Yindom LM (2015) Detection of a novel KIR3DL1*0150210 allele by sequencing. Tissue Antigens, 86(4), 311.
Wang L, Zhang Y, Dong T, Rowland-Jones SL & Yindom L-M (2015) Detection of a novelKIR3DL1*0150210allele by sequencing. Tissue Antigens, 86(4), 311-311.
Wang L, Zhang Y, Dong T, Rowland-Jones SL & Yindom L-M (2015) KIR3DS1*0130109: a novel activating three-domain KIR identified using sequence-based typing. Tissue Antigens, 86(3), 222-223.
Jallow S, Leligdowicz A, Kramer HB, Onyango C, Cotten M, Wright C, Whittle HC, McMichael A, Dong T, Kessler BM & Rowland-Jones SL (2015) The presence of prolines in the flanking region of an immunodominant HIV-2 gag epitope influences the quality and quantity of the epitope generated. European Journal of Immunology, 45(8), 2232-2242.
Yindom L-M, de Silva TI & Rowland-Jones SL (2015) Full-length sequence ofKIR3DL1*0310102detected in DNA samples from West Africa. Tissue Antigens, 86(4), 312-313.
Yindom L-M, James K, de Silva TI & Rowland-Jones SL (2015) KIR3DL1*0040102- a novel three-domain KIR subtype isolated from donors of African descent. Tissue Antigens, 86(3), 220-221.
Yindom L-M, de Silva TI & Rowland-Jones SL (2015) KIR3DL1*0250103: a novel three-domain KIR allele isolated in West African samples. Tissue Antigens, 86(2), 150-151.
Yindom LM, Wang L, Xu K, Dong T & Rowland-Jones SL (2015) The identification of a killer cell immunoglobulin-like receptor 3DL1*0150209 in an Asian population using molecular techniques. Tissue Antigens, 86(2), 152-153.
Jallow S, Jallow S, Leligdowicz A, Kramer HB, Onyango C, Cotten M, Wright C, Whittle HC, Mcmichael A, Dong T , Kessler BM et al (2015) The presence of prolines in the flanking region of an immunodominant HIV-2 gag epitope influences the quality and quantity of the epitope generated. European Journal of Immunology.
Yindom L-M, Wang L, Xu K, Dong T & Rowland-Jones SL (2015) The identification of a killer cell immunoglobulin-like receptor3DL1*0150209in an Asian population using molecular techniques. Tissue Antigens, 86(2), 152-153.
Yindom L-M, James K, de Silva TI & Rowland-Jones SL (2015) A novelKIR3DL1*0150103subtype identified in West Africa. Tissue Antigens, 86(1), 70-71.
Shepherd BL, Ferrand R, Munyati S, Folkard S, Boyd K, Bandason T, Jallow S, Rowland-Jones SL & Yindom L-M (2015) HLA Correlates of Long-Term Survival in Vertically Infected HIV-1-Positive Adolescents in Harare, Zimbabwe. AIDS Research and Human Retroviruses, 31(5), 504-507.
Wang L, Xu K, Dong T, Rowland-Jones SL & Yindom L-M (2015) KIR3DS1*0130111: a novel KIR allele identified using molecular typing methods. Tissue Antigens, 85(4), 296-297.
Makvandi-Nejad S & Rowland-Jones S (2015) How does the humoral response to HIV-2 infection differ from HIV-1 and can this explain the distinct natural history of infection with these two human retroviruses?. Immunology Letters, 163(1), 69-75.
Yindom L-M, James K, de Silva TI & Rowland-Jones SL (2014) Isolation of full-length genomic sequences of theKIR3DL1*0040103allele from African donors using sequence-based techniques. Tissue Antigens, 84(6), 594-595.
Yindom L-M, Wong G, de Silva TI & Rowland-Jones SL (2014) Complete genomic sequence ofKIR3DL1*0150102. Tissue Antigens, 84(6), 595-596.
Yindom L-M, de Silva TI & Rowland-Jones SL (2014) Description of a novelKIR3DL1*0150211allele isolated using molecular techniques. Tissue Antigens, 84(6), 596-597.
Yindom L-M, Wong G, de Silva TI & Rowland-Jones SL (2014) A new variant of killer-cell immunoglobulin-like receptorKIR3DL1*03101isolated using sequence-based techniques. Tissue Antigens, 84(5), 521-522.
Yindom L-M, James K, de Silva TI & Rowland-Jones SL (2014) Genomic full length sequence of a novel killer-cell immunoglobulin-like receptor,KIR3DL1*0010103identified by sequencing. Tissue Antigens, 84(5), 520-521.
Yindom LM, Wang L, Dong T & Rowland-Jones SL (2014) Full length KIR3DS1*0130110 allele isolated by SBT. Tissue Antigens, 84(4), 423-424.
Yindom LM, Wang L, Zhang Y, Rowland-Jones SL & Dong T (2014) KIR3DS1*0130108 isolated using full length sequence-based typing. Tissue Antigens, 84(2), 251-252.
Yindom L-M, Wang L, Rai MA, Dong T & Rowland-Jones SL (2014) Report of a novel activating killer-cell immunoglobulin-like receptor allele3DS1*078identified using sequence-based typing. Tissue Antigens, 84(2), 252-254.
Yindom L-M, Wang L, Xu K, Dong T & Rowland-Jones SL (2014) A novel KIR3DS1*0130107 allele isolated by sequencing from an Asian donor. International Journal of Immunogenetics, 41(3), 267-268.
Wang L, Zhang YH, Dong T, Rowland-Jones SL & Yindom LM (2014) A novel full-length KIR3DS1*0130106 allele identified by sequencing. Tissue Antigens, 83(5), 371-372.
Wang L, Xu K, Dong T, Rowland-Jones SL & Yindom LM (2014) Identification of KIR3DL1*0150208 using long-range sequence-based techniques. Tissue Antigens, 83(5), 372-373.
Kanki PJ & Rowland-Jones S (2014) The protective effect of HIV-2 infection. AIDS, 28(7), 1065-1067.
Noho-Konteh F, Adetifa J, Cox M, Forster T, Drammeh A, Njie-Jobe J, Jeffries D, Plebanski M, Ghazal P, Dickinson P , Whittle H et al (2014) Sex differences in immune responses to vaccines. International Journal of Infectious Diseases, 21, 65-65.
Afran L, Garcia Knight M, Nduati E, Urban BC, Heyderman RS & Rowland-Jones SL (2014) HIV-exposed uninfected children: a growing population with a vulnerable immune system?. Clinical & Experimental Immunology, 176(1), 11-22.
Wang L, Yindom LM, Rowland-Jones SL & Dong T (2014) Identification of the KIR3DL1*0050105 allele by sequence-based techniques. Tissue Antigens, 83(4), 301-302.
Wang L, Yan H, Dong T, Rowland-Jones SL & Yindom L-M (2014) Detection of a novel killer-cell immunoglobulin-like receptor allele - KIR3DL1*0150207 - in Asian individuals. Tissue Antigens, 83(4), 304-305.
Yindom L-M, Wang L, Dong T, Rowland-Jones SL & Zhang Y (2014) TheKIR3DS1*0130105allele identified using high-resolution sequence-based typing. Tissue Antigens, 83(4), 302-303.
Yindom L-M, Wang L, Rowland-Jones SL & Dong T (2014) Killer-cell immunoglobulin-like receptor gene3DL1*077isolated using long-range sequence-based techniques. Tissue Antigens, 83(3), 206-207.
Yindom LM, Wang L, Dong T & Rowland-Jones SL (2014) A novel KIR3DL1*0070104 allele found in individuals from Asia. Tissue Antigens, 83(3), 204-206.
Abidi SH, Shahid A, Lakhani LS, Shah R, Okinda N, Ojwang P, Abbas F, Rowland-Jones S & Ali S (2014) HIV-1 progression links with viral genetic variability and subtype, and patient's HLA type: Analysis of a Nairobi-Kenyan cohort. Medical Microbiology and Immunology, 203(1), 57-63.
Yindom LM, Wang L, Rowland-Jones SL & Dong T (2014) Two novel KIR3DL1 alleles, 3DL1*0150205 and 3DL1*0150206, identified by full-length DNA sequencing. Tissue Antigens, 83(2), 128-129.
Yindom LM, Wang L, Okala SG, Dong T & Rowland-Jones SL (2014) Report of a novel KIR3DS1*0130104 allele discovered using advanced molecular techniques. Tissue Antigens, 83(2), 121-122.
Yindom LM, Wang L, Dong T & Rowland-Jones SL (2014) Full-length genomic sequence of a new KIR3DL1*0150203 allele. Tissue Antigens, 83(2), 122-123.
Yindom LM, Wang L, Dong T & Rowland-Jones SL (2014) Identification of KIR3DL1*0200101 by long-range sequence-based techniques. Tissue Antigens, 83(2), 127-128.
Yindom LM, Wang L, Dong T & Rowland-Jones SL (2014) Long-range sequencing revealed a new KIR3DL1*0150204 allele in 20 individuals of Asian descent. Tissue Antigens, 83(2), 123-124.
Yindom LM, Wang L, Dong T & Rowland-Jones SL (2014) Description of a novel KIR3DL1*0050104 allele identified using sequence-based techniques. Tissue Antigens, 83(2), 124-125.
Yindom L-M, Wang L, Dong T & Rowland-Jones SL (2014) Full lengthKIR3DS1*0130110allele isolated by SBT. Tissue Antigens, 84(4), 423-424.
Yindom L-M, James K, de Silva TI & Rowland-Jones SL (2014) Full-lengthKIR3DL1*022detected in an African donor. Tissue Antigens, 84(4), 427-429.
Yindom L-M, Wang L, Zhang Y, Rowland-Jones SL & Dong T (2014) KIR3DS1*0130108isolated using full length sequence-based typing. Tissue Antigens, 84(2), 251-252.
Yindom L-M, Wang L, Rai MA, Rowland-Jones SL & Dong T (2014) Report of a novel activating killer-cell immunoglobulin-like receptor allele 3DS1078 identified using sequence-based typing. Tissue Antigens.
Wang L, Zhang YH, Dong T, Rowland-Jones SL & Yindom L-M (2014) A novel full-lengthKIR3DS1*0130106allele identified by sequencing. Tissue Antigens, 83(5), 371-372.
Wang L, Xu K, Dong T, Rowland-Jones SL & Yindom L-M (2014) Identification ofKIR3DL1*0150208using long-range sequence-based techniques. Tissue Antigens, 83(5), 372-373.
Wang L, Rowland-Jones SL, Yindom L-M, Yan H & Dong T (2014) Detection of a novel killer-cell immunoglobulin-like receptor allele - KIR3DL1*0150207 - in asian individuals. Tissue Antigens.
Yindom L-M, de Silva TI & Rowland-Jones SL (2014) A novelKIR3DL1*0200102allele isolated from a West African donor by sequence-based typing. Tissue Antigens, 83(4), 305-306.
Yindom L-M, Wang L, Dong T & Rowland-Jones SL (2014) A novelKIR3DL1*0070104allele found in individuals from Asia. Tissue Antigens, 83(3), 204-206.
Wang L, Yindom L-M, Rowland-Jones SL & Dong T (2014) Identification of theKIR3DL1*0050105allele by sequence-based techniques. Tissue Antigens, 83(4), 301-302.
Yindom L-M, Wang L, Rowland-Jones SL & Dong T (2014) Killer-cell immunoglobulin-like receptor gene 3DL1*077 isolated using long-range sequence-based techniques. Tissue Antigens.
Yindom L-M, Wang L, Dong T & Rowland-Jones SL (2014) Long-range sequencing revealed a newKIR3DL1*0150204allele in 20 individuals of Asian descent. Tissue Antigens, 83(2), 123-124.
Yindom L-M, Wang L, Rowland-Jones SL & Dong T (2014) Two novel KIR3DL1 alleles,3DL1*0150205and3DL1*0150206, identified by full-length DNA sequencing. Tissue Antigens, 83(2), 128-129.
Abidi SH, Shahid A, Lakhani LS, Shah R, Okinda N, Ojwang P, Abbas F, Rowland-Jones S & Ali S (2014) HIV-1 progression links with viral genetic variability and subtype, and patient’s HLA type: analysis of a Nairobi-Kenyan cohort. Medical Microbiology and Immunology, 203(1), 57-63.
Yindom L-M, Wang L, Okala SG, Dong T & Rowland-Jones SL (2014) Report of a novelKIR3DS1*0130104allele discovered using advanced molecular techniques. Tissue Antigens, 83(2), 121-122.
Yindom L-M, Wang L, Dong T & Rowland-Jones SL (2014) Identification ofKIR3DL1*0200101by long-range sequence-based techniques. Tissue Antigens, 83(2), 127-128.
Yindom L-M, Wang L, Dong T & Rowland-Jones SL (2014) Description of a novelKIR3DL1*0050104allele identified using sequence-based techniques. Tissue Antigens, 83(2), 124-125.
Yindom L-M, Wang L, Dong T & Rowland-Jones SL (2014) Full-length genomic sequence of a newKIR3DL1*0150203allele. Tissue Antigens, 83(2), 122-123.
Yindom L-M, de Silva TI & Rowland-Jones SL (2014) Full-length sequence ofKIR3DL1*01501allele found in Sub-Saharan Africa by long-range sequencing. Tissue Antigens, 83(2), 126-127.
Yindom LM, Wang L, Rowland-Jones SL & Dong T (2013) A novel full length KIR3DL1*0070103 identified by molecular typing. Tissue Antigens, 82(6), 445-446.
Yindom LM, Wang L, Dong T & Rowland-Jones SL (2013) Identification of KIR3DL1*0050103 by the sequence-based techniques. Tissue Antigens, 82(6), 444-445.
Rai MA, Zhang Y, Yindom L-M, Holmes J, Yu L-M, Hao C, Rostron T, Yan H, Zhang YL, Cai C , Mcmichael AJ et al (2013) HLA correlates in a cohort of slow progressors from China. AIDS, 27(17), 2822-2824.
de Silva T, Peng Y, Leligdowicz A, Zaidi I, Li L, Griffin H, Blais M-E, Vincent T, Saraiva M, Yindom L-M , van Tienen C et al (2013) The role of CD8+ T-cell responses in the pathogenesis of HIV-2, a naturally contained human retroviral infection. Journal of Infection, 67(4), 344-344.
Nyamweya S, Hegedus A, Jaye A, Rowland-Jones S, Flanagan KL & Macallan DC (2013) Comparing HIV-1 and HIV-2 infection: Lessons for viral immunopathogenesis. Reviews in Medical Virology, 23(4), 221-240.
Abidi SH, Shahid A, Lakhani LS, Khanani MR, Ojwang P, Okinda N, Shah R, Abbas F, Rowland-Jones S & Ali S (2013) Population-specific evolution of HIV Gag epitopes in genetically diverged patients. Infection, Genetics and Evolution, 16, 78-86.
de Silva TI, Peng Y, Leligdowicz A, Zaidi I, Li L, Griffin H, Blais M-E, Vincent T, Saraiva M, Yindom L-M , van Tienen C et al (2013) Correlates of T-cell–mediated viral control and phenotype of CD8+ T cells in HIV-2, a naturally contained human retroviral infection. Blood, 121(21), 4330-4339.
Rai MA, Zhang Y-H, Yan H-P, Zhao Y, Abidi SH, Qu W-Y, McMichael A, Dong T, Rowland-Jones S & Xu K-Y (2013) ST111 Immune selection and vpu variability in a unique narrow source HIV-Positive village cohort. JAIDS Journal of Acquired Immune Deficiency Syndromes, 62, S69-S69.
Glanville JM, Taylor S, Baban D, Gillespie G, Easterbrook P, Stewart-Jones G, Simmons A, Rowland-Jones S, Dong T & McMichael A (2013) Antigen-sensitive CD8 T-cell clones with tough HIV-1 suppression. The Lancet, 381, S44-S44.
Yindom L-M, Wang L, Rowland-Jones SL & Dong T (2013) A novel full lengthKIR3DL1*0070103identified by molecular typing. Tissue Antigens, 82(6), 445-446.
Yindom L-M, Wang L, Dong T & Rowland-Jones SL (2013) Identification ofKIR3DL1*0050103by the sequence-based techniques. Tissue Antigens, 82(6), 444-445.
de Silva TI, van Tienen C, Onyango C, Jabang A, Vincent T, Loeff MFSVD, Coutinho RA, Jaye A, Rowland-Jones S, Whittle H , Cotten M et al (2013) Population dynamics of HIV-2 in rural West Africa. AIDS, 27(1), 125-134.
Stewart-Jones GB, Simpson P, Anton van der Merwe P, Easterbrook P, McMichael AJ, Rowland-Jones SL, Jones EY & Gillespie GM (2012) Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms. Proceedings of the National Academy of Sciences, 109(50), E3483-E3492.
(2012) Effect of HIV-2 Infection on HIV-1 Disease Progression. New England Journal of Medicine, 367(20), 1961-1963.
Lee LY-H, Ha DLA, Simmons C, de Jong MD, Chau NVV, Schumacher R, Peng YC, McMichael AJ, Farrar JJ, Smith GL , Townsend ARM et al (2012) Memory T cells established by seasonal human influenza A infection cross-react with avian influenza A (H5N1) in healthy individuals. Journal of Clinical Investigation, 122(11), 4301-4301.
Kong R, Li H, Georgiev I, Changela A, Bibollet-Ruche F, Decker JM, Rowland-Jones SL, Jaye A, Guan Y, Lewis GK , Langedijk JPM et al (2012) Epitope Mapping of Broadly Neutralizing HIV-2 Human Monoclonal Antibodies. Journal of Virology, 86(22), 12115-12128.
Lohman-Payne B, Slyker JA, Moore S, Maleche-Obimbo E, Wamalwa DC, Richardson BA, Rowland-Jones S, Mbori-Ngacha D, Farquhar C, Overbaugh J & John-Stewart G (2012) Breast milk cellular HIV-specific interferon γ responses are associated with protection from peripartum HIV transmission. AIDS, 26(16), 2007-2016.
Slyker JA, Rowland-Jones SL, Dong T, Reilly M, Richardson B, Emery VC, Atzberger A, Mbori-Ngacha D, Lohman-Payne BL & John-Stewart GC (2012) Acute Cytomegalovirus Infection Is Associated with Increased Frequencies of Activated and Apoptosis-Vulnerable T Cells in HIV-1-Infected Infants. Journal of Virology, 86(20), 11373-11379.
Zaidi I, Peterson K, Jeffries D, Whittle H, de Silva T, Rowland-Jones S, Jaye A & de Jong BC (2012) Immune Reconstitution Inflammatory Syndrome and the Influence of T Regulatory Cells: A Cohort Study in the Gambia. PLoS ONE, 7(6). View this article in WRRO
Blais M-E, Zhang Y, Rostron T, Griffin H, Taylor S, Xu K, Yan H, Wu H, James I, John M , Dong T et al (2012) High Frequency of HIV Mutations Associated with HLA-C Suggests Enhanced HLA-C–Restricted CTL Selective Pressure Associated with an AIDS-Protective Polymorphism. The Journal of Immunology, 188(9), 4663-4670.
Khalid M, Yu H, Sauter D, Usmani SM, Schmokel J, Feldman J, Gruters RA, van der Ende ME, Geyer M, Rowland-Jones S , Osterhaus AD et al (2012) Efficient Nef-Mediated Downmodulation of TCR-CD3 and CD28 Is Associated with High CD4+ T Cell Counts in Viremic HIV-2 Infection. Journal of Virology, 86(9), 4906-4920.
Lohman-Payne B, Slyker J & Rowland-Jones SL (2012) Immune approaches for the prevention of breast milk transmission of HIV-1. Advances in Experimental Medicine and Biology, 743, 185-195.
Sabbah S, Jagne YJ, Zuo J, de Silva T, Ahasan MM, Brander C, Rowland-Jones S, Flanagan KL & Hislop AD (2012) T-cell immunity to Kaposi sarcoma–associated herpesvirus: recognition of primary effusion lymphoma by LANA-specific CD4+ T cells. Blood, 119(9), 2083-2092.
de Silva TI, Aasa-Chapman M, Cotten M, Hue S, Robinson J, Bibollet-Ruche F, Sarge-Njie R, Berry N, Jaye A, Aaby P , Whittle H et al (2012) Potent Autologous and Heterologous Neutralizing Antibody Responses Occur in HIV-2 Infection across a Broad Range of Infection Outcomes. Journal of Virology, 86(2), 930-946.
Peterson K & Rowland-Jones S (2012) Novel agents for the treatment of HIV-2 infection. Antiviral Therapy, 17(3), 435-438.
Culshaw A, Dong T & Rowland-Jones SL (2012) A 2 Amino Acid Shift in Position Leads to a Substantial Difference in the Pattern of Processing of 2 HIV-1 Epitopes. JAIDS Journal of Acquired Immune Deficiency Syndromes, 59(4), 335-339.
Gourlay AJ, van Tienen C, Dave SS, Vincent T, Rowland-Jones SL, Glynn JR, Whittle HC & van der Loeff MFS (2012) Clinical predictors cannot replace biological predictors in HIV-2 infection in a community setting in West Africa. International Journal of Infectious Diseases, 16(5), e337-e343.
Gourlay AJ, van Tienen C, Dave SS, Vincent T, Rowland-Jones SL, Glynn JR, Whittle HC & van der Loeff MFS (2012) Clinical predictors cannot replace biological predictors in HIV-2 infection in a community setting in West Africa. International Journal of Infectious Diseases.
Njie-Jobe J, Nyamweya S, Miles DJC, van der Sande M, Zaman S, Touray E, Hossin S, Adetifa J, Palmero M, Burl S , Jeffries D et al (2012) Immunological impact of an additional early measles vaccine in Gambian children: Responses to a boost at 3 years. Vaccine, 30(15), 2543-2550.
Njie-Jobe J, Nyamweya S, Miles DJC, van der Sande M, Zaman S, Touray E, Hossin S, Adetifa J, Palmero M, Burl S , Jeffries D et al (2012) Immunological impact of an additional early measles vaccine in Gambian children: Responses to a boost at 3 years. Vaccine, 30(15), 2543-2550.
Powell TJ, Fox A, Peng Y, Quynh Mai LT, Lien VTK, Hang NLK, Wang L, Lee LY-H, Simmons CP, McMichael AJ , Farrar JJ et al (2012) Identification of H5N1-Specific T-Cell Responses in a High-risk Cohort in Vietnam Indicates the Existence of Potential Asymptomatic Infections. The Journal of Infectious Diseases, 205(1), 20-27.
Stewart B, Jobarteh ML, Sarge-Njie R, Alabi A, de Silva T, Peterson K, Peterson I, Whittle H, Rowland-Jones S, Jaye A , Cotten M et al (2011) Emergence of HBV resistance to lamivudine (3TC) in HIV/HBV co-infected patients in The Gambia, West Africa. BMC Research Notes, 4. View this article in WRRO
van Tienen C, van der Loeff MS, Peterson I, Cotten M, Andersson S, Holmgren B, Vincent T, de Silva T, Rowland-Jones S, Aaby P & Whittle H (2011) HTLV-1 and HIV-2 Infection Are Associated with Increased Mortality in a Rural West African Community. PLoS ONE, 6(12). View this article in WRRO
Rai MA, Chun Hao S, Blais M-E, Rostron T, Zhang Y, Xu KY, Yan H, McMichael AJ, Dong T & Rowland-Jones S (2011) HLA allele distributions and associations in a cohort of LTNPs from China. Retrovirology, 8(S1).
Peterson I, Togun O, de Silva T, Oko F, Rowland-Jones S, Jaye A & Peterson K (2011) Mortality and immunovirological outcomes on antiretroviral therapy in HIV-1 and HIV-2-infected individuals in the Gambia. AIDS, 25(17), 2167-2175.
Blais M-E, Dong T & Rowland-Jones S (2011) HLA-C as a mediator of natural killer and T-cell activation: spectator or key player?. Immunology, 133(1), 1-7.
Peterson K, Jallow S, Rowland-Jones SL & de Silva TI (2011) Antiretroviral Therapy for HIV-2 Infection: Recommendations for Management in Low-Resource Settings. AIDS Research and Treatment, 2011. View this article in WRRO
Zhang Y, Peng Y, Yan H, Xu K, Saito M, Wu H, Chen X, Ranasinghe S, Kuse N, Powell T , Zhao Y et al (2011) Multilayered Defense in HLA-B51–Associated HIV Viral Control. The Journal of Immunology, 187(2), 684-691.
Ota MOC, Odutola AA, Owiafe PK, Donkor S, Owolabi OA, Brittain NJ, Williams N, Rowland-Jones S, Hill AVS, Adegbola RA & McShane H (2011) Immunogenicity of the tuberculosis vaccine MVA85A is reduced by coadministration with EPI vaccines in a randomized controlled trial in gambian infants. Science Translational Medicine, 3(88).
Hodges-Mameletzis I, De Bree GJ & Rowland-Jones SL (2011) An underestimated lentivirus model: what can HIV-2 research contribute to the development of an effective HIV-1 vaccine?. Expert Review of Anti-infective Therapy, 9(2), 195-206.
Rowland-Jones S (2010) Botswana's painful journey. Nature Medicine, 16(12), 1367-1367.
de Silva TI, Turner R, Hué S, Trikha R, van Tienen C, Onyango C, Jaye A, Foley B, Whittle H, Rowland-Jones SL & Cotten M (2010) HIV-1 subtype distribution in the Gambia and the significant presence of CRF49_cpx, a novel circulating recombinant form. Retrovirology, 7(1). View this article in WRRO
Yindom L-M, Leligdowicz A, Martin MP, Gao X, Qi Y, Zaman SMA, van der Loeff MS, van Tienen C, Jaye A, Aveika A , Worwui A et al (2010) Influence of HLA Class I and HLA-KIR Compound Genotypes on HIV-2 Infection and Markers of Disease Progression in a Manjako Community in West Africa. Journal of Virology, 84(16), 8202-8208.
Leligdowicz A, Onyango C, Yindom L-M, Peng Y, Cotten M, Jaye A, McMichael A, Whittle H, Dong T & Rowland-Jones S (2010) Highly avid, oligoclonal, early-differentiated antigen-specific CD8+ T cells in chronic HIV-2 infection. European Journal of Immunology, 40(7), 1963-1972.
van Tienen C, van der Loeff M, Peterson I, Cotten M, Holmgren B, Andersson S, Vincent T, Sarge-Njie R, Rowland-Jones S, Jaye A , Aaby P et al (2010) HTLV-1 in rural Guinea-Bissau: prevalence, incidence and a continued association with HIV between 1990 and 2007. Retrovirology, 7(1), 50-50.
Sutherland JS, Young JM, Peterson KL, Sanneh B, Whittle HC, Rowland-Jones SL, Adegbola RA, Jaye A & Ota MOC (2010) Polyfunctional CD4+ and CD8+ T Cell Responses to Tuberculosis Antigens in HIV-1–Infected Patients before and after Anti-Retroviral Treatment. The Journal of Immunology, 184(11), 6537-6544.
Onyango CO, Leligdowicz A, Yokoyama M, Sato H, Song H, Nakayama EE, Shioda T, de Silva T, Townend J, Jaye A , Whittle H et al (2010) HIV-2 capsids distinguish high and low virus load patients in a West African community cohort. Vaccine, 28, B60-B67.
de Silva TI, van Tienen C, Rowland-Jones SL & Cotten M (2010) Dual infection with HIV-1 and HIV-2: double trouble or destructive interference?. HIV Therapy, 4(3), 305-323.
Makadzange AT, Gillespie G, Dong T, Kiama P, Bwayo J, Kimani J, Plummer F, Easterbrook P & Rowland-Jones SL (2010) Characterization of an HLA-C-restricted CTL response in chronic HIV infection. European Journal of Immunology, 40(4), 1036-1041.
Tienen CV, van der Loeff MS, Zaman SMA, Vincent T, Sarge-Njie R, Peterson I, Leligdowicz A, Jaye A, Rowland-Jones S, Aaby P & Whittle H (2010) Two Distinct Epidemics: The Rise of HIV-1 and Decline of HIV-2 Infection Between 1990 and 2007 in Rural Guinea-Bissau. JAIDS Journal of Acquired Immune Deficiency Syndromes, 53(5), 640-647.
Mendy ME, Welzel T, Lesi OA, Hainaut P, Hall AJ, Kuniholm MH, McConkey S, Goedert JJ, Kaye S, Rowland-Jones S , Whittle H et al (2010) Hepatitis B viral load and risk for liver cirrhosis and hepatocellular carcinoma in The Gambia, West Africa. Journal of Viral Hepatitis, 17(2), 115-122.
Walther B, Miles DJC, Crozier S, Waight P, Palmero MS, Ojuola O, Touray E, Sande MVD, Whittle H, Rowland-Jones S & Flanagan KL (2010) Placental Malaria is associated with reduced early life weight development of affected children independent of low birth weight. Malaria Journal, 9(1).
Leligdowicz A, Feldmann J, Jaye A, Cotten M, Dong T, McMichael A, Whittle H & Rowland‐Jones S (2010) Direct Relationship between Virus Load and Systemic Immune Activation in HIV‐2 Infection. The Journal of Infectious Diseases, 201(1), 114-122.
Kaul R, MacDonald KS, Nagelkerke NJ, Kimani J, Fowke K, Ball TB, Luo M, Kariri A, Jaoko W, Moses S , Rowland-Jones S et al (2010) HIV viral set point and host immune control in individuals with HIV-specific CD8+ T-cell responses prior to HIV acquisition. AIDS, 24(10), 1449-1454.
Flanagan KL, Halliday A, Burl S, Landgraf K, Jagne YJ, Noho-Konteh F, Townend J, Miles DJC, van der Sande M, Whittle H & Rowland-Jones S (2010) The effect of placental malaria infection on cord blood and maternal immunoregulatory responses at birth. European Journal of Immunology, 40(4), 1062-1072.
Jobarteh M, Malfroy M, Peterson I, Jeng A, Sarge-Njie R, Alabi A, Peterson K, Cotten M, Hall A, Rowland-Jones S , Whittle H et al (2010) Seroprevalence of hepatitis B and C virus in HIV-1 and HIV-2 infected Gambians. Virology Journal, 7.
Dung NTP, Duyen HTL, Thuy NTV, Ngoc TV, Chau NVV, Hien TT, Rowland-Jones SL, Dong T, Farrar J, Wills B & Simmons CP (2010) Timing of CD8+ T Cell Responses in Relation to Commencement of Capillary Leakage in Children with Dengue. The Journal of Immunology, 184(12), 7281-7287.
Lohman-Payne B, Slyker J & Rowland-Jones SL (2010) Immune-based Approaches to the Prevention of Mother-to-child Transmission of HIV-1: Active and Passive Immunization. Clinics in Perinatology, 37(4), 787-805.
Burl S, Adetifa UJ, Cox M, Touray E, Ota MO, Marchant A, Whittle H, McShane H, Rowland-Jones SL & Flanagan KL (2010) Delaying Bacillus Calmette-Guérin Vaccination from Birth to 4 1/2 Months of Age Reduces Postvaccination Th1 and IL-17 Responses but Leads to Comparable Mycobacterial Responses at 9 Months of Age. The Journal of Immunology, 185(4), 2620-2628.
Feldmann J, Leligdowicz A, Jaye A, Dong T, Whittle H & Rowland-Jones SL (2009) Downregulation of the T-Cell Receptor by Human Immunodeficiency Virus Type 2 Nef Does Not Protect against Disease Progression. Journal of Virology, 83(24), 12968-12972.
Sharma D, Bastard K, Guethlein LA, Norman PJ, Yawata N, Yawata M, Pando M, Thananchai H, Dong T, Rowland-Jones S , Brodsky FM et al (2009) Dimorphic Motifs in D0 and D1+D2 Domains of Killer Cell Ig-Like Receptor 3DL1 Combine to Form Receptors with High, Moderate, and No Avidity for the Complex of a Peptide Derived from HIV and HLA-A*2402. The Journal of Immunology, 183(7), 4569-4582.
Slyker J, Dong T, John-Stewart G, Lohman-Payne B, Reilly M, Atzberger A, Taylor S, Maleche-Obimbo E, Mbori-Ngacha D & Rowland-Jones S (2009) Phenotypic characterization of HIV-specific CD8 T cells during acute infant HIV infection. Retrovirology, 6(Suppl 1), O7-O7.
Jallow S, Alabi A, Sarge-Njie R, Peterson K, Whittle H, Corrah T, Jaye A, Cotten M, Vanham G, McConkey SJ , Rowland-Jones S et al (2009) Virological Response to Highly Active Antiretroviral Therapy in Patients Infected with Human Immunodeficiency Virus Type 2 (HIV-2) and in Patients Dually Infected with HIV-1 and HIV-2 in The Gambia and Emergence of Drug-Resistant Variants. Journal of Clinical Microbiology, 47(7), 2200-2208.
Jallow S, Vincent T, Leligdowicz A, De Silva T, Van Tienen C, Alabi A, Sarge‐Njie R, Aaby P, Corrah T, Whittle H , Jaye A et al (2009) Presence of a Multidrug‐Resistance Mutation in an HIV‐2 Variant Infecting a Treatment‐Naive Individual in Caio, Guinea Bissau. Clinical Infectious Diseases, 48(12), 1790-1793.
Blais M-E & Rowland-Jones S (2009) Lessons from the failure of the adenovector HIV vaccine. F1000 Biology Reports.
Thananchai H, Makadzange T, Maenaka K, Kuroki K, Peng Y, Conlon C, Rowland-Jones S & Dong T (2009) Reciprocal recognition of an HLA-Cw4-restricted HIV-1 gp120 epitope by CD8+ T cells and NK cells. AIDS, 23(2), 189-193.
John‐Stewart GC, Mbori‐Ngacha D, Payne BL, Farquhar C, Richardson BA, Emery S, Otieno P, Obimbo E, Dong T, Slyker J , Nduati R et al (2009) HIV‐1–Specific Cytotoxic T Lymphocytes and Breast Milk HIV‐1 Transmission. The Journal of Infectious Diseases, 199(6), 889-898.
Lohman-Payne B, Slyker JA, Richardson BA, Farquhar C, Majiwa M, Maleche-Obimbo E, Mbori-Ngacha D, Overbaugh J, Rowland-Jones S & John-Stewart G (2009) Infants with late breast milk acquisition of HIV-1 generate interferon-gamma responses more rapidly than infants with early peripartum acquisition. Clinical & Experimental Immunology, 156(3), 511-517.
Mabuka JM, Mackelprang RD, Lohman-Payne B, Majiwa M, Bosire R, John-Stewart G, Rowland-Jones S, Overbaugh J & Farquhar C (2009) CCR2-64I Polymorphism Is Associated With Lower Maternal HIV-1 Viral Load and Reduced Vertical HIV-1 Transmission. JAIDS Journal of Acquired Immune Deficiency Syndromes, 51(2), 235-237.
Webster DP, Farrar J & Rowland-Jones S (2009) Progress towards a dengue vaccine. The Lancet Infectious Diseases, 9(11), 678-687.
Ranasinghe S, Kramer H, Wright C, Kessler B, Zhang Y, Gillespie G, Rowland-Jones S, McMichael A & Dong T (2009) P17-28 LB. The antiviral efficacy of HIV-specific CD8+ T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate. Retrovirology, 6(Suppl 3), P410-P410.
Slyker JA, Lohman-Payne BL, John-Stewart GC, Maleche-Obimbo E, Emery S, Richardson B, Dong T, Iversen AKN, Mbori-Ngacha D, Overbaugh J , Emery VC et al (2009) Acute cytomegalovirus infection in Kenyan HIV-infected infants. AIDS, 23(16), 2173-2181.
Slyker JA, Lohman-Payne BL, Rowland-Jones SL, Otieno P, Maleche-Obimbo E, Richardson B, Farquhar C, Mbori-Ngacha D, Emery VC & John-Stewart GC (2009) The detection of cytomegalovirus DNA in maternal plasma is associated with mortality in HIV-1-infected women and their infants. AIDS, 23(1), 117-124.
Ondondo BO, Rowland-Jones SL, Dorrell L, Peterson K, Cotten M, Whittle H & Jaye A (2008) Comprehensive analysis of HIV Gag-specific IFN-γ response in HIV-1- and HIV-2-infected asymptomatic patients from a clinical cohort in The Gambia. European Journal of Immunology, 38(12), 3549-3560.
de Silva TI, Cotten M & Rowland-Jones SL (2008) HIV-2: the forgotten AIDS virus. Trends in Microbiology, 16(12), 588-595.
Gottlieb GS, Eholié S-P, Nkengasong JN, Jallow S, Rowland-Jones S, Whittle HC & Sow PS (2008) A call for randomized controlled trials of antiretroviral therapy for HIV-2 infection in West Africa. AIDS, 22(16), 2069-2072.
Mendy ME, Kaye S, Le Roux E, Kirk GD, Jeng-Barry A, McConkey S, Cotten M, Kuniholm MH, Leligdowicz A, Hainaut P , Rowland-Jones S et al (2008) Application of a Novel, Rapid, and Sensitive Oligonucleotide Ligation Assay for Detection of Cancer-Predicting Mutations in the Precore and Basal Core Promoter of Hepatitis B Virus. Journal of Clinical Microbiology, 46(8), 2723-2730.
Miles DJC, Sanneh M, Holder B, Crozier S, Nyamweya S, Touray ES, Palmero MS, Zaman SMA, Rowland-Jones S, van der Sande M & Whittle H (2008) Cytomegalovirus infection induces T-cell differentiation without impairing antigen-specific responses in Gambian infants. Immunology, 124(3), 388-400.
Miles DJC, van der Sande M, Crozier S, Ojuola O, Palmero MS, Sanneh M, Touray ES, Rowland-Jones S, Whittle H, Ota M & Marchant A (2008) Effects of Antenatal and Postnatal Environments on CD4 T-Cell Responses to Mycobacterium bovis BCG in Healthy Infants in The Gambia. Clinical and Vaccine Immunology, 15(6), 995-1002.
Rowland-Jones S & De Silva T (2008) Erratum: Resisting immune exhaustion in HIV-1 infection(PLoSMed (2008), 5, (5), (e103), DOI: 10.1371/journal.pmed.0050103).. PLoS Medicine, 5(6), 1005.
Kaye S, Miles D, Antoine P, Burny W, Ojuola B, Kaye P, Rowland‐Jones S, Whittle H, Sande MVD & Marchant A (2008) Virological and Immunological Correlates of Mother‐to‐Child Transmission of Cytomegalovirus in The Gambia. The Journal of Infectious Diseases, 197(9), 1307-1314.
Rowland-Jones S & de Silva T (2008) Resisting Immune Exhaustion in HIV-1 Infection. PLoS Medicine, 5(5), 721-724. View this article in WRRO
Slyker JA, Payne BL, John-Stewart GC, Obimbo E, Emery S, Richardson B, Dong T, Mbori-Ngacha D, Overbaugh J, Emery VC & Rowland-Jones SL (2008) Primary CMV infection: a co-factor HIV-1 disease progression in African infants?. Retrovirology, 5(Suppl 1), O23-O23.
Leligdowicz A & Rowland-Jones S (2008) Tenets of protection from progression to AIDS: lessons from the immune responses to HIV-2 infection. Expert Review of Vaccines, 7(3), 319-331.
Miles DJC, Sande MVD, Kaye S, Crozier S, Ojuola O, Palmero MS, Sanneh M, Touray ES, Waight P, Rowland‐Jones S , Whittle H et al (2008) CD4+T Cell Responses to Cytomegalovirus in Early Life: A Prospective Birth Cohort Study. The Journal of Infectious Diseases, 197(5), 658-662.
Hammond AS, McConkey SJ, Hill PC, Crozier S, Klein MR, Adegbola RA, Rowland‐Jones S, Brookes RH, Whittle H & Jaye A (2008) Mycobacterial T Cell Responses in HIV‐Infected Patients with Advanced Immunosuppression. The Journal of Infectious Diseases, 197(2), 295-299.
(2008) News and EFIS – Eur. J. Immunol. 1/2008. European Journal of Immunology, 38(1), 11-14.
Seale AC, de Jong BC, Zaidi I, Duvall M, Whittle H, Rowland-Jones S & Jaye A (2008) Effects of cryopreservation on CD4+ CD25+ T cells of HIV-1 infected individuals. Journal of Clinical Laboratory Analysis, 22(3), 153-158.
Moran E, Simmons C, Vinh Chau N, Luhn K, Wills B, Dung NP, Thao LTT, Hien TT, Farrar J, Rowland-Jones S & Dong T (2008) Preservation of a critical epitope core region is associated with the high degree of flaviviral cross-reactivity exhibited by a dengue-specific CD4+ T cell clone. European Journal of Immunology, 38(4), 1050-1057.
Abidi SHI, Dong T, Vuong MT, Sreenu VB, Rowland-Jones SL, Evans EJ & Davis SJ (2008) Differential remodeling of a T-cell transcriptome following CD8- versus CD3-induced signaling. Cell Research, 18(6), 641-648.
Walton RT & Rowland-Jones SL (2008) HIV and Chemokine Binding to Red Blood Cells—DARC Matters. Cell Host & Microbe, 4(1), 3-5.
Duvall MG, Precopio ML, Ambrozak DA, Jaye A, McMichael AJ, Whittle HC, Roederer M, Rowland-Jones SL & Koup RA (2008) Polyfunctional T cell responses are a hallmark of HIV-2 infection. European Journal of Immunology, 38(2), 350-363.
Rowland-Jones S & Dong T (2007) Dying T cells trigger autoimmunity in HIV. Nature Medicine, 13(12), 1413-1415.
Leligdowicz A, Yindom L-M, Onyango C, Sarge-Njie R, Alabi A, Cotten M, Vincent T, da Costa C, Aaby P, Jaye A , Dong T et al (2007) Robust Gag-specific T cell responses characterize viremia control in HIV-2 infection. Journal of Clinical Investigation, 117(10), 3067-3074.
Dong T, Moran E, Chau NV, Simmons C, Peng Y, Hien TT, McMichael A, Farrar J & Rowland-Jones S (2007) High pro-inflammatory cytokine secretion and selective depletion of high avidity cross-reactive cytotoxic T-cells in the pathogenesis of acute secondary dengue virus infection. Journal of Infection, 55(3), e38-e39.
Miles DJC, van der Sande M, Jeffries D, Kaye S, Ismaili J, Ojuola O, Sanneh M, Touray ES, Waight P, Rowland-Jones S , Whittle H et al (2007) Cytomegalovirus Infection in Gambian Infants Leads to Profound CD8 T-Cell Differentiation. Journal of Virology, 81(11), 5766-5776.
Jallow S, Kaye S, Schutten M, Brandin E, Albert J, McConkey SJ, Corrah T, Whittle H, Vanham G, Rowland-Jones S & Janssens W (2007) Development and Evaluation of an Oligonucleotide Ligation Assay for Detection of Drug Resistance-Associated Mutations in the Human Immunodeficiency Virus Type 2 pol Gene. Journal of Clinical Microbiology, 45(5), 1565-1571.
Molyneux M (2007) UK doctors are already put off by changes in training. BMJ, 334(7596), 709.3-710.
Rowland-Jones SL & Whittle HC (2007) Out of Africa: what can we learn from HIV-2 about protective immunity to HIV-1?. Nature Immunology, 8(4), 329-331.
Gillespie GMA, Bashirova A, Dong T, McVicar DW, Rowland-Jones SL & Carrington M (2007) Lack of KIR3DS1 Binding to MHC Class I Bw4 Tetramers in Complex with CD8+ T Cell Epitopes. AIDS Research and Human Retroviruses, 23(3), 451-455.
Reinis M, Weiser B, Kuiken C, Dong T, Lang D, Nachman S, Zhang Y, Rowland-Jones S & Burger H (2007) Genomic Analysis of HIV Type 1 Strains Derived from a Mother and Child Pair of Long-Term Nonprogressors. AIDS Research and Human Retroviruses, 23(2), 309-315.
Thananchai H, Gillespie G, Martin MP, Bashirova A, Yawata N, Yawata M, Easterbrook P, McVicar DW, Maenaka K, Parham P , Carrington M et al (2007) Cutting Edge: Allele-Specific and Peptide-Dependent Interactions between KIR3DL1 and HLA-A and HLA-B. The Journal of Immunology, 178(1), 33-37.
Do ng T, Moran E, Luhn K, Peng Y, McMichael A, Rowland-Jones S, Simmons C, Wills B, Dung NP, Farrar J , Chau NV et al (2007) High pro-inflammatory cytokine secretion and loss of high avidity cross-reactive cytotoxic T-cells during the course of secondary dengue virus infection. PLoS ONE, 2(12).
Lühn K, Simmons CP, Moran E, Dung NTP, Chau TNB, Quyen NTH, Thao LTT, Van Ngoc T, Dung NM, Wills B , Farrar J et al (2007) Increased frequencies of CD4+CD25high regulatory T cells in acute dengue infection. Journal of Experimental Medicine, 204(5), 979-985.
Hene L, Sreenu VB, Vuong MT, Abidi SHI, Sutton JK, Rowland-Jones SL, Davis SJ & Evans EJ (2007) Deep analysis of cellular transcriptomes – LongSAGE versus classic MPSS. BMC Genomics, 8(1), 333-333.
Duvall MG, Loré K, Blaak H, Ambrozak DA, Adams WC, Santos K, Geldmacher C, Mascola JR, McMichael AJ, Jaye A , Whittle HC et al (2007) Dendritic Cells Are Less Susceptible to Human Immunodeficiency Virus Type 2 (HIV-2) Infection than to HIV-1 Infection. Journal of Virology, 81(24), 13486-13498.
Rowland-Jones S (2006) Protective immunity against HIV infection: lessons from HIV-2 infection. Future Microbiology, 1(4), 427-433.
Jallow S, Kaye S, Brandin E, Albert J, Vanham G, Whittle H, Rowland-Jones S & Janssens W (2006) Development and evaluation of the oligonucleotide ligation assay (OLA) for the detection of drug resistance mutations in HIV-2 patients on antiretroviral therapy. Retrovirology, 3(S1).
Rowland-Jones S & Dong T (2006) Tired T cells turn around. Nature, 443(7109), 282-283.
Gillespie GMA, Stewart-Jones G, Rengasamy J, Beattie T, Bwayo JJ, Plummer FA, Kaul R, McMichael AJ, Easterbrook P, Dong T , Jones EY et al (2006) Strong TCR Conservation and Altered T Cell Cross-Reactivity Characterize a B*57-Restricted Immune Response in HIV-1 Infection. The Journal of Immunology, 177(6), 3893-3902.
Jallow S, Kaye S, Alabi A, Aveika A, Sarge-Njie R, Sabally S, Corrah T, Whittle H, Vanham G, Rowland-Jones S , Janssens W et al (2006) Virological and immunological response to Combivir and emergence of drug resistance mutations in a cohort of HIV-2 patients in The Gambia. AIDS, 20(10), 1455-1458.
Nuvor SV, van der Sande M, Rowland-Jones S, Whittle H & Jaye A (2006) Natural Killer Cell Function Is Well Preserved in Asymptomatic Human Immunodeficiency Virus Type 2 (HIV-2) Infection but Similar to That of HIV-1 Infection When CD4 T-Cell Counts Fall. Journal of Virology, 80(5), 2529-2538.
Makadzange AT, Gillespie G, Kimani J, Kiama P, Easterbrook P, Bwayo JJ & Rowland-Jones SL (2006) Identification of a novel HLA B*57 restricted cytotoxic T-lymphocyte epitope within HIV-1 rev. AIDS, 20(3), 462-464.
Cebere I, Dorrell L, McShane H, Simmons A, McCormack S, Schmidt C, Smith C, Brooks M, Roberts JE & Darwin SC (2006) Phase I clinical trial safety of DNA- and modified virus Ankara-vectored human immunodeficiency virus type 1 (HIV-1) vaccines administered alone and in a prime-boost regime to healthy HIV-1-uninfected volunteers. Vaccine, 24(4), 417-425.
Mendy ME, Kirk G, Jeng-Barry A, Kaye S, McConkey S, Le Roux E, Hainaut P, Whittle H & Rowland-Jones S (2006) P.377 Novel oligonucleotide assay detects HBV pre-core and basal core mutations in HBV-infected Gambians. Journal of Clinical Virology, 36, S177-S177.
Ondondo BO, Yang H, Dong T, di Gleria K, Suttill A, Conlon C, Brown D, Williams P, Rowland-Jones SL, Hanke T , McMichael AJ et al (2006) Immunisation with recombinant modified vaccinia virus Ankara expressing HIV-1 gag in HIV-1-infected subjects stimulates broad functional CD4+ T cell responses. European Journal of Immunology, 36(10), 2585-2594.
Dorrell L, Yang H, Ondondo B, Dong T, di Gleria K, Suttill A, Conlon C, Brown D, Williams P, Bowness P , Goonetilleke N et al (2006) Expansion and Diversification of Virus-Specific T Cells following Immunization of Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Individuals with a Recombinant Modified Vaccinia Virus Ankara/HIV-1 Gag Vaccine. Journal of Virology, 80(10), 4705-4716.
Duvall MG, Jaye A, Dong T, Brenchley JM, Alabi AS, Jeffries DJ, van der Sande M, Togun TO, McConkey SJ, Douek DC , McMichael AJ et al (2006) Maintenance of HIV-Specific CD4+ T Cell Help Distinguishes HIV-2 from HIV-1 Infection. The Journal of Immunology, 176(11), 6973-6981.
Chakraborty R, Reinis M, Rostron T, Philpott S, Dong T, D'Agostino A, Musoke R, Silva E, Stumpf M, Weiser B , Burger H et al (2006) nef gene sequence variation among HIV-1-infected African children*. HIV Medicine, 7(2), 75-84.
Jallow S, Kaye S, Alabi A, Aveika A, McConkey S, Rowland-Jones S & Janssens W (2005) . Retrovirology, 2(Suppl 1), S134-S134.
Thimme R, Appay V, Koschella M, Panther E, Roth E, Hislop AD, Rickinson AB, Rowland-Jones SL, Blum HE & Pircher H (2005) Increased Expression of the NK Cell Receptor KLRG1 by Virus-Specific CD8 T Cells during Persistent Antigen Stimulation. Journal of Virology, 79(18), 12112-12116.
Dorrell L, Yang H, Iversen AKN, Conlon C, Suttill A, Lancaster M, Dong T, Cebere I, Edwards A, Rowland-Jones S , Hanke T et al (2005) Therapeutic immunization of highly active antiretroviral therapy-treated HIV-1-infected patients: safety and immunogenicity of an HIV-1 gag/poly-epitope DNA vaccine. AIDS, 19(12), 1321-1323.
Gillespie GMA, Pinheiro S, Sayeid-Al-Jamee M, Alabi A, Kaye S, Sabally S, Sarge-Njie R, Njai H, Joof K, Jaye A , Whittle H et al (2005) CD8+ T?cell responses to human immunodeficiency viruses type?2 (HIV-2) and type?1 (HIV-1) gag proteins are distinguishable by magnitude and breadth but not cellular phenotype. European Journal of Immunology, 35(5), 1445-1453.
Boutboul F, Puthier D, Appay V, Pellé O, Ait-Mohand H, Combadière B, Carcelain G, Katlama C, Rowland-Jones SL, Debré P , Nguyen C et al (2005) Modulation of interleukin-7 receptor expression characterizes differentiation of CD8 T cells specific for HIV, EBV and CMV. AIDS, 19(17), 1981-1986.
Lohman BL, Slyker JA, Richardson BA, Farquhar C, Mabuka JM, Crudder C, Dong T, Obimbo E, Mbori-Ngacha D, Overbaugh J , Rowland-Jones S et al (2005) Longitudinal Assessment of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific Gamma Interferon Responses during the First Year of Life in HIV-1-Infected Infants. Journal of Virology, 79(13), 8121-8130.
Simmons CP, Dong T, Chau NV, Dung NTP, Chau TNB, Thao LTT, Dung NT, Hien TT, Rowland-Jones S & Farrar J (2005) Early T-Cell Responses to Dengue Virus Epitopes in Vietnamese Adults with Secondary Dengue Virus Infections. Journal of Virology, 79(9), 5665-5675.
Stewart-Jones GBE, Gillespie G, Overton IM, Kaul R, Roche P, McMichael AJ, Rowland-Jones S & Jones EY (2005) Structures of Three HIV-1 HLA-B*5703-Peptide Complexes and Identification of Related HLAs Potentially Associated with Long-Term Nonprogression. The Journal of Immunology, 175(4), 2459-2468.
Chakraborty R, Morel A-S, Sutton JK, Appay V, Ripley RM, Dong T, Rostron T, Ogola S, Palakudy T, Musoke R , D’Agostino A et al (2005) Correlates of Delayed Disease Progression in HIV-1-Infected Kenyan Children. The Journal of Immunology, 174(12), 8191-8199.
Missale G, Papagno L, Penna A, Pilli M, Zerbini A, Vitali P, Pieroni G, Urbani S, Uggeri J, Pinheiro S , Rowland-Jones S et al (2004) Parenteral exposure to high HIV viremia leads to virus-specific T cell priming without evidence of infection. European Journal of Immunology, 34(11), 3208-3215.
Kaul R, Rutherford J, Rowland-Jones SL, Kimani J, Onyango JI, Fowke K, MacDonald K, Bwayo JJ, McMichael AJ & Plummer FA (2004) HIV-1 Env-specific cytotoxic T-lymphocyte responses in exposed, uninfected Kenyan sex workers. AIDS, 18(15), 2087-2089.
Mwau M, Cebere I, Sutton J, Chikoti P, Winstone N, Wee EG-T, Beattie T, Chen Y-H, Dorrell L, McShane H , Schmidt C et al (2004) A human immunodeficiency virus 1 (HIV-1) clade A vaccine in clinical trials: stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans. Journal of General Virology, 85(4), 911-919.
Appay V & Rowland-Jones SL (2004) Lessons from the study of T-cell differentiation in persistent human virus infection. Seminars in Immunology, 16(3), 205-212.
Fang G, Kuiken C, Weiser B, Rowland‐Jones S, Plummer F, Chen C, Kaul R, Omu Anzala A, Bwayo J, Kimani J , Philpott SM et al (2004) Long‐Term Survivors in Nairobi: Complete HIV‐1 RNA Sequences and Immunogenetic Associations. The Journal of Infectious Diseases, 190(4), 697-701.
Farquhar C, Rowland-Jones S, Mbori-Ngacha D, Redman M, Lohman B, Slyker J, Otieno P, Obimbo E, Rostron T, Ochieng J , Oyugi J et al (2004) Human Leukocyte Antigen (HLA) B*18 and Protection against Mother-to-Child HIV Type 1 Transmission. AIDS Research and Human Retroviruses, 20(7), 692-697.
Beattie T, Kaul R, Rostron T, Dong T, Easterbrook P, Jaoko W, Kimani J, Plummer F, McMichael A & Rowland-Jones S (2004) Screening for HIV-specific T-cell responses using overlapping 15-mer peptide pools or optimized epitopes. AIDS, 18(11), 1595-1598.
Shi B, Philpott SM, Weiser B, Kuiken C, Brunner C, Fang G, Fowke KR, Plummer FA, Rowland-Jones S, Bwayo J , Anzala AO et al (2004) Construction of an Infectious HIV Type 1 Molecular Clone from an African Patient with a Subtype D/C Recombinant Virus. AIDS Research and Human Retroviruses, 20(9), 1015-1018.
Fang G, Weiser B, Kuiken C, Philpott SM, Rowland-Jones S, Plummer F, Kimani J, Shi B, Kaul R, Bwayo J , Anzala O et al (2004) Recombination following superinfection by HIV-1. AIDS, 18(2), 153-159.
Hansasuta P, Dong T, Thananchai H, Weekes M, Willberg C, Aldemir H, Rowland-Jones S & Braud VM (2004) Recognition of HLA-A3 and HLA-A11 by KIR3DL2 is peptide-specific. European Journal of Immunology, 34(6), 1673-1679.
Rowland-Jones S (2004) AIDS pathogenesis: what have two decades of research taught us?. Bulletin et mémoires de l'Académie royale de médecine de Belgique, 159(Pt 2), 171-175.
Dong T, Stewart-Jones G, Chen N, Easterbrook P, Xu X, Papagno L, Appay V, Weekes M, Conlon C, Spina C , Little S et al (2004) HIV-specific Cytotoxic T Cells from Long-Term Survivors Select a Unique T Cell Receptor. Journal of Experimental Medicine, 200(12), 1547-1557.
Mongkolsapaya J, Dejnirattisai W, Xu X-N, Vasanawathana S, Tangthawornchaikul N, Chairunsri A, Sawasdivorn S, Duangchinda T, Dong T, Rowland-Jones S , Yenchitsomanus P-T et al (2003) Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever. Nature Medicine, 9(7), 921-927.
Marchant A, Appay V, van der Sande M, Dulphy N, Liesnard C, Kidd M, Kaye S, Ojuola O, Gillespie GMA, Vargas Cuero AL , Cerundolo V et al (2003) Mature CD8+ T lymphocyte response to viral infection during fetal life. Journal of Clinical Investigation, 111(11), 1747-1755.
Kaul R, Thottingal P, Kimani J, Kiama P, Waigwa CW, Bwayo JJ, Plummer FA & Rowland-Jones SL (2003) Quantitative ex vivo analysis of functional virus-specific CD8 T lymphocytes in the blood and genital tract of HIV-infected women. AIDS, 17(8), 1139-1144.
Kaul R, Thottingal P, Kimani J, Kiama P, Waigwa CW, Bwayo JJ, Plummer FA & Rowland-Jones SL (2003) Quantitative ex vivo analysis of functional virus-specific CD8 T lymphocytes in the blood and genital tract of HIV-infected women. AIDS, 17(8), 1139-1144.
Dorrell L, Yang H, Conlon C, Suttill A, Lancaster M, Edwards A, Rowland-Jones S, Hanke T & McMichael A (2003) A Pilot Study of the Safety and Inununogenicity of An HIV-1 Clade a Gag/Multiepitope DNA Vaccine, pTHr.HIVA, in HIV-1 Seropositive Subjects Receiving Highly Active Antiretroviral Therapy. Clinical Science, 104(s49), 54P-54P.
Nelson PN (2003) Demystified . . . Human endogenous retroviruses. Molecular Pathology, 56(1), 11-18.
Rowland-Jones SL (2003) AIDS pathogenesis: what have two decades of HIV research taught us?. Nature Reviews Immunology, 3(4), 343-348.
Shiroishi M, Tsumoto K, Amano K, Shirakihara Y, Colonna M, Braud VM, Allan DSJ, Makadzange A, Rowland-Jones S, Willcox B , Jones EY et al (2003) Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G. Proceedings of the National Academy of Sciences, 100(15), 8856-8861.
Lohman BL, Slyker J, Mbori‐Ngacha D, Bosire R, Farquhar C, Obimbo E, Otieno P, Nduati R, Rowland‐Jones S & John‐Stewart G (2003) Prevalence and Magnitude of Human Immunodeficiency Virus (HIV) Type 1–Specific Lymphocyte Responses in Breast Milk from HIV‐1–Seropositive Women. The Journal of Infectious Diseases, 188(11), 1666-1674.
Whelan KT, Lin C-L, Cella M, McMichael AJ, Austyn JM & Rowland-Jones SL (2003) The HIV protease inhibitor Indinavir reduces immature dendritic cell transendothelial migration. European Journal of Immunology, 33(9), 2520-2530.
Chakraborty R, Rees G, Bourboulia D, Cross AM, Dixon JR, D’Agostino A, Musoke R, Boshoff C, Rowland‐Jones SL & Klenerman P (2003) Viral Coinfections among African Children Infected with Human Immunodeficiency Virus Type 1. Clinical Infectious Diseases, 36(7), 922-924.
Evans EJ, Hene L, Sparks LM, Dong T, Retiere C, Fennelly JA, Manso-Sancho R, Powell J, Braud VM, Rowland-Jones SL , McMichael AJ et al (2003) The T Cell Surface—How Well Do We Know It?. Immunity, 19(2), 213-223.
PAPAGNO L, APPAY V, SUTTON J, ROSTRON T, GILLESPIE GMA, OGG GS, KING A, MAKADZANHGE AT, WATERS A, BALOTTA C , VYAKARNAM A et al (2002) Comparison between HIV- and CMV-specific T cell responses in long-term HIV infected donors. Clinical and Experimental Immunology, 130(3), 509-517.
Appay V & Rowland-Jones SL (2002) Premature ageing of the immune system: the cause of AIDS?. Trends in Immunology, 23(12), 580-585.
McMichael AJ & Rowland-Jones SL (2002) Bad news for stop–start therapy?. Nature, 420(6914), 371-373.
Özdemir E, St. John LS, Gillespie G, Rowland-Jones S, Champlin RE, Molldrem JJ & Komanduri KV (2002) Cytomegalovirus reactivation following allogeneic stem cell transplantation is associated with the presence of dysfunctional antigen-specific CD8+ T cells. Blood, 100(10), 3690-3697.
Rowland-Jones SL & Lohman B (2002) Interactions between malaria and HIV infection—an emerging public health problem?. Microbes and Infection, 4(12), 1265-1270.
Appay V & Rowland-Jones SL (2002) The assessment of antigen-specific CD8+ T cells through the combination of MHC class I tetramer and intracellular staining. Journal of Immunological Methods, 268(1), 9-19.
Bird TG, Kaul R, Rostron T, Kimani J, Embree J, Dunn PPJ, Bwayo JJ, Plummer FA, Rowland-Jones SL & Dong T (2002) HLA typing in a Kenyan cohort identifies novel class I alleles that restrict cytotoxic T-cell responses to local HIV-1 clades. AIDS, 16(14), 1899-1904.
Sutton JK, Chakraborty R, Kaul R, Rostron T, D'Agostino A, Kiama P, Kimani J, Bwayo J & Rowland-Jones SL (2002) Vigorous HIV-Specific CD4 T Cell Responses in IIIV-1 Infected African Children and Adults in the Absence of Antiretroviral Therapy. Clinical Science, 103(s47), 29P-30P.
&NA; (2002) Scientific considerations for the regulation and clinical evaluation of HIV/AIDS preventive vaccines. AIDS, 16(10), W15-W25.
Appay V, Papagno L, Spina CA, Hansasuta P, King A, Jones L, Ogg GS, Little S, McMichael AJ, Richman DD & Rowland-Jones SL (2002) Dynamics of T Cell Responses in HIV Infection. The Journal of Immunology, 169(1), 607.2-607.
Appay V, Papagno L, Spina CA, Hansasuta P, King A, Jones L, Ogg GS, Little S, McMichael AJ, Richman DD & Rowland-Jones SL (2002) Erratum: Dynamics of T cell responses in HIV infection (The Journal of Immunology (2002) 168 (3660-3666)). Journal of Immunology, 169(1), 607.
Appay V, Zaunders JJ, Papagno L, Sutton J, Jaramillo A, Waters A, Easterbrook P, Grey P, Smith D, McMichael AJ , Cooper DA et al (2002) Characterization of CD4+ CTLs Ex Vivo. The Journal of Immunology, 168(11), 5954-5958.
Kaul R, Rowland‐Jones SL, Gillespie G, Kimani J, Dong T, Kiama P, Simonsen JN, Bwayo JJ, McMichael AJ & Plummer FA (2002) Gonococcal Cervicitis Is Associated with Reduced Systemic CD8+T Cell Responses in Human Immunodeficiency Virus Type 1–Infected and Exposed, Uninfected Sex Workers. The Journal of Infectious Diseases, 185(10), 1525-1529.
Beattie T, Rowland-Jones S & Kaul R (2002) HIV-1 and AIDS: what are protective immune responses?. Journal of HIV therapy, 7(2), 35-39.
Gillespie GMA, Kaul R, Dong T, Yang H-B, Rostron T, Bwayo JJ, Kiama P, Peto T, Plummer FA, McMichael AJ & Rowland-Jones SL (2002) Cross-reactive cytotoxic T lymphocytes against a HIV-1 p24 epitope in slow progressors with B*57. AIDS, 16(7), 961-972.
Appay V, Papagno L, Spina CA, Hansasuta P, King A, Jones L, Ogg GS, Little S, McMichael AJ, Richman DD & Rowland-Jones SL (2002) Dynamics of T Cell Responses in HIV Infection. The Journal of Immunology, 168(7), 3660-3666.
Appay V, Hansasuta P, Sutton J, Schrier RD, Wong JK, Furtado M, Havlir DV, Wolinsky SM, McMichael AJ, Richman DD , Rowland-Jones SL et al (2002) Persistent HIV-1-specific cellular responses despite prolonged therapeutic viral suppression. AIDS, 16(2), 161-170.
Appay V, Dunbar PR, Callan M, Klenerman P, Gillespie GMA, Papagno L, Ogg GS, King A, Lechner F, Spina CA , Little S et al (2002) Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections. Nature Medicine, 8(4), 379-385.
Polycarpou A, Ntais C, Korber BT, Elrich HA, Winchester R, Krogstad P, Wolinsky S, Rostron T, Rowland-Jones SL, Ammann AJ & Ioannidis JPA (2002) Association between Maternal and Infant Class I and II HLA Alleles and of Their Concordance with the Risk of Perinatal HIV Type 1 Transmission. AIDS Research and Human Retroviruses, 18(11), 741-746.
Chakraborty R, Gillespie GMA, Reinis M, Rostron T, Dong T, Philpott S, Burger H, Weiser B, Peto T & Rowland-Jones SL (2002) HIV-1-specific CD8 T cell responses in a pediatric slow progressor infected as a premature neonate. AIDS, 16(15), 2085-2087.
Oxenius , Sewell , Dawson , Günthard , Fischer , Gillespie , Rowland-Jones , Fagard , Hirschel , Phillips & David A. Price for the Swiss HIV Cohort Study (2002) . Journal of Clinical Immunology, 22(6), 363-374.
Weiss RA (2001) Preface. British Medical Bulletin, 58(1), 1-2.
Kaul R, Rowland-Jones SL, Kimani J, Fowke K, Dong T, Kiama P, Rutherford J, Njagi E, Mwangi F, Rostron T , Onyango J et al (2001) New insights into HIV-1 specific cytotoxic T-lymphocyte responses in exposed, persistently seronegative Kenyan sex workers. Immunology Letters, 79(1-2), 3-13.
Rowland-Jones SL, Pinheiro S, Kaul R, Hansasuta P, Gillespie G, Dong T, Plummer FA, Bwayo JB, Fidler S, Weber J , McMichael A et al (2001) How important is the ‘quality’ of the cytotoxic T lymphocyte (CTL) response in protection against HIV infection?. Immunology Letters, 79(1-2), 15-20.
Fang G, Burger H, Chappey C, Rowland-Jones S, Visosky A, Chen C-H, Moran T, Townsend L, Murray M & Weiser B (2001) Analysis of Transition from Long-Term Nonprogressive to Progressive Infection Identifies Sequences that May Attenuate HIV Type 1. AIDS Research and Human Retroviruses, 17(15), 1395-1404.
Vyakarnam A, Eyeson J, Teo I, Zuckerman M, Babaahmady K, Schuitemaker H, Shaunak S, Rostron T, Rowland-Jones S, Simmons G & Clapham P (2001) Evidence for a post-entry barrier to R5 HIV-1 infection of CD4 memory T cells. AIDS, 15(13), 1613-1626.
John GC, Bird T, Overbaugh J, Nduati R, Mbori‐Ngacha D, Rostron T, Dong T, Kostrikis L, Richardson B & Rowland‐Jones SL (2001) CCR5 Promoter Polymorphisms in a Kenyan Perinatal Human Immunodeficiency Virus Type 1 Cohort: Association with Increased 2‐Year Maternal Mortality. The Journal of Infectious Diseases, 184(1), 89-92.
Dorrell L, Willcox BE, Yvonne Jones E, Gillespie G, Njai H, Sabally S, Jaye A, Degleria K, Rostron T, Lepin E , McMichael A et al (2001) Cytotoxic T lymphocytes recognize structurally diverse, clade-specific and cross-reactive peptides in human immunodeficiency virus type-1 gag through HLA-B53. European Journal of Immunology, 31(6), 1747-1756.
Kaul R, Dong T, Plummer FA, Kimani J, Rostron T, Kiama P, Njagi E, Irungu E, Farah B, Oyugi J , Chakraborty R et al (2001) CD8+ lymphocytes respond to different HIV epitopes in seronegative and infected subjects. Journal of Clinical Investigation, 107(10), 1303-1310.
McMichael AJ & Rowland-Jones SL (2001) Cellular immune responses to HIV. Nature, 410(6831), 980-987.
Elliott T, Bonneville M, Kruisbeek A, Walker PR, Glaichenhaus N, Rowland-Jones S, Casanova JL, Liu Y, Wood K, Bushell A & Green A (2001) Immunology. Current Opinion in Immunology, 13(2), 121-128.
Rowland-Jones S (2001) HIV: Vaccines out of Africa. Biologist, 48(2), 64-66.
Champagne P, Ogg GS, King AS, Knabenhans C, Ellefsen K, Nobile M, Appay V, Rizzardi GP, Fleury S, Lipp M , Förster R et al (2001) Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature, 410(6824), 106-111.
Rowland-Jones S, Pinheiro S & Kaul R (2001) New Insights into Host Factors in HIV-1 Pathogenesis. Cell, 104(4), 473-476.
Appay V & Rowland-Jones SL (2001) RANTES: a versatile and controversial chemokine. Trends in Immunology, 22(2), 83-87.
Hansasuta P & Rowland-Jones SL (2001) HIV-1 transmission and acute HIV-1 infection. British Medical Bulletin, 58(1), 109-127.
Kaul R, Rowland-Jones SL, Kimani J, Dong T, Yang H-B, Kiama P, Rostron T, Njagi E, Bwayo JJ, MacDonald KS , McMichael AJ et al (2001) Late seroconversion in HIV-resistant Nairobi prostitutes despite pre-existing HIV-specific CD8+ responses. Journal of Clinical Investigation, 107(3), 341-349.
MacDonald KS, Matukas L, Embree JE, Fowke K, Kimani J, Nagelkerke NJD, Oyugi J, Kiama P, Kaul R, Luscher MA , Rowland-Jones S et al (2001) Human leucocyte antigen supertypes and immune susceptibility to HIV-1, implications for vaccine design. Immunology Letters, 79(1-2), 151-157.
Kelleher AD, Long C, Holmes EC, Allen RL, Wilson J, Conlon C, Workman C, Shaunak S, Olson K, Goulder P , Brander C et al (2001) Clustered Mutations in HIV-1 Gag Are Consistently Required for Escape from Hla-B27–Restricted Cytotoxic T Lymphocyte Responses. Journal of Experimental Medicine, 193(3), 375-386.
Elliott T, Bonneville M, Kruisbeek A, Liu Y, Casolaro V, Glaichenhaus N, Rowland-Jones S, Casanova J-L, Walker PR, Gorham J & Green A (2000) Immunology. Current Opinion in Immunology, 12(5), 487-495.
Kaul R, Makadzange T & Rowland-Jones S (2000) AIDS in Africa: a disaster no longer waiting to happen. Nature Immunology, 1(4), 267-270.
Gillespie GMA, Wills MR, Appay V, O'Callaghan C, Murphy M, Smith N, Sissons P, Rowland-Jones S, Bell JI & Moss PAH (2000) Functional Heterogeneity and High Frequencies of Cytomegalovirus-Specific CD8+ T Lymphocytes in Healthy Seropositive Donors. Journal of Virology, 74(17), 8140-8150.
McMichael AJ, Callan M, Appay V, Hanke T, Ogg G & Rowland–Jones S (2000) The dynamics of the cellular immune response to HIV infection: implications for vaccination. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 355(1400), 1007-1011.
Elliott T, Bonneville M, Kruisbeek A, Liu Y, Casolaro V, Glaichenhaus N, Rowland-Jones S, Casanova J-L, Walker PR, Wood K , Bushell A et al (2000) Immunology. Current Opinion in Immunology, 12(4), 355-364.
Kelleher AD & Rowland-Jones SL (2000) Functions of tetramer-stained HIV-specific CD4+ and CD8+ T cells. Current Opinion in Immunology, 12(4), 370-374.
Appay V, Dunbar PR, Cerundolo V, McMichael A, Czaplewski L & Rowland-Jones S (2000) RANTES activates antigen-specific cytotoxic T lymphocytes in a mitogen-like manner through cell surface aggregation. International Immunology, 12(8), 1173-1182.
Appay V, Nixon DF, Donahoe SM, Gillespie GMA, Dong T, King A, Ogg GS, Spiegel HML, Conlon C, Spina CA , Havlir DV et al (2000) HIV-Specific Cd8+ T Cells Produce Antiviral Cytokines but Are Impaired in Cytolytic Function. Journal of Experimental Medicine, 192(1), 63-76.
Dorrell L, Hessell AJ, Wang M, Whittle H, Sabally S, Rowland-Jones S, Burton DR & Parren PWHI (2000) Absence of specific mucosal antibody responses in HIV-exposed uninfected sex workers from the Gambia. AIDS, 14(9), 1117-1122.
Elliot T, Bonneville M, Kruisbeek A, Liu Y, Casolaro V, Glaichenhaus N, Rowland-Jones S, Casanova J-L, Walker PR, Wood K , Bushell A et al (2000) Immunology. Current Opinion in Immunology, 12(3), 227-235.
Elliot T, Bonneville M, Kruisbeek A, Liu Y, Casolaro V, Glaichenhaus N, Rowland-Jones S, Casanova J-L, Walker PR, Wood K , Bushell A et al (2000) Immunology. Current Opinion in Immunology, 12(2), 131-138.
Wilson JDK, Ogg GS, Allen RL, Davis C, Shaunak S, Downie J, Dyer W, Workman C, Sullivan JS, McMichael AJ & Rowland-Jones SL (2000) Direct visualization of HIV-1-specific cytotoxic T lymphocytes during primary infection. AIDS, 14(3), 225-233.
Elliott T, Bonneville M, Kruisbeek A, Liu Y, Rowland-Jones S, Casanova J-L, Walker PR, Wood K & Bushell A (2000) Immunology. Current Opinion in Immunology, 12(1), 1-7.
Kaul R, Plummer FA, Kimani J, Dong T, Kiama P, Rostron T, Njagi E, MacDonald KS, Bwayo JJ, McMichael AJ & Rowland-Jones SL (2000) HIV-1-Specific Mucosal CD8+ Lymphocyte Responses in the Cervix of HIV-1-Resistant Prostitutes in Nairobi. The Journal of Immunology, 164(3), 1602-1611.
Dela Cruz CS, Tan R, Rowland-Jones SL & Barber BH (2000) Creating HIV-1 reverse transcriptase cytotoxic T lymphocyte target structures by HLA-A2 heavy chain modifications. International Immunology, 12(9), 1293-1302.
John GC, Rousseau C, Dong T, Rowland-Jones S, Nduati R, Mbori-Ngacha D, Rostron T, Kreiss JK, Richardson BA & Overbaugh J (2000) Maternal SDF1 3′A Polymorphism Is Associated with Increased Perinatal Human Immunodeficiency Virus Type 1 Transmission. Journal of Virology, 74(12), 5736-5739.
Dorrell L, O’Callaghan CA, Britton W, Hambleton S, McMichael A, Smith GL, Rowland-Jones S & Blanchard TJ (2000) Recombinant modified vaccinia virus Ankara efficiently restimulates human cytotoxic T lymphocytes in vitro. Vaccine, 19(2-3), 327-336.
Elliott T, Bonneville M, Kruisbeek A, Liu Y, Rowland-Jones S, Casanova J-L, Walker PR, Wood K & Bushell A (1999) Immunology. Current Opinion in Immunology, 11(6), 593-600.
Goulder PJ, Rowland-Jones SL, McMichael AJ & Walker BD (1999) Anti-HIV cellular immunity: recent advances towards vaccine design.. AIDS (London, England), 13 Suppl A.
Easterbrook PJ, Rostron T, Ives N, Troop M, Gazzard BG & Rowland‐Jones SL (1999) Chemokine Receptor Polymorphisms and Human Immunodeficiency Virus Disease Progression. The Journal of Infectious Diseases, 180(4), 1096-1105.
Elliott T, Bonneville M, Kruisbeek A, Liu Y, Ono S, Rodosevich M, Rowland-Jones S, Casanova J-L, Walker PR, Wood K & Bushell A (1999) Immunology. Current Opinion in Immunology, 11(5), 475-483.
Hemsley C, Abraham S & Rowland‐Jones S (1999) Corynebacterium pseudodiphtheriticum—A Skin Pathogen. Clinical Infectious Diseases, 29(4), 938-939.
Rowland-Jones S (1999) HIV infection: where have all the T cells gone?. The Lancet, 354(9172), 5-7.
Rowland-Jones S (1999) The role of chemokine receptors in HIV infection. Sexually Transmitted Infections, 75(3), 148-151.
Rice PS, Cybulska B, Parry JV, Rowland-Jones S & Daniels RS (1999) Reappearance of HIV antibody in an infected, seronegative individual after treatment with highly active antiretroviral therapy. AIDS, 13(6), 729-729.
Rowland-Jones SL (1999) HIV: The deadly passenger in dendritic cells. Current Biology, 9(7), R248-R250.
Tan R, Xu X, Ogg GS, Hansasuta P, Dong T, Rostron T, Luzzi G, Conlon CP, Screaton GR, McMichael AJ & Rowland-Jones S (1999) Rapid Death of Adoptively Transferred T Cells in Acquired Immunodeficiency Syndrome. Blood, 93(5), 1506-1510.
Tan R, Xu X, Ogg GS, Hansasuta P, Dong T, Rostron T, Luzzi G, Conlon CP, Screaton GR, McMichael AJ & Rowland-Jones S (1999) Rapid Death of Adoptively Transferred T Cells in Acquired Immunodeficiency Syndrome. Blood, 93(5), 1506-1510.
Rowland-Jones S (1999) Long-term non-progression in HIV infection: Clinico pathological issues. Journal of Infection, 38(2), 67-70.
Elliott T, Bonneville M, Kruisbeek AM, Liu Y, Ono S, Rowland-Jones S, Casanova J-L, Walker PR, Wood K & Bushell A (1999) Immunology. Current Opinion in Immunology, 11(1), 1-8.
Dorrell L, Dong T, Ogg GS, Lister S, McAdam S, Rostron T, Conlon C, McMichael AJ & Rowland-Jones SL (1999) Distinct Recognition of Non-Clade B Human Immunodeficiency Virus Type 1 Epitopes by Cytotoxic T Lymphocytes Generated from Donors Infected in Africa. Journal of Virology, 73(2), 1708-1714.
Tan LC, Gudgeon N, Annels NE, Hansasuta P, O'Callaghan CA, Rowland-Jones S, McMichael AJ, Rickinson AB & Callan MFC (1999) A re-evaluation of the frequency of CD8⁺ T cells specific for EBV in healthy virus carriers. Journal of Immunology, 162(3), 1827-1835.
Dyer WB, Ogg GS, Demoitie M-A, Jin X, Geczy AF, Rowland-Jones SL, McMichael AJ, Nixon DF & Sullivan JS (1999) Strong Human Immunodeficiency Virus (HIV)-Specific Cytotoxic T-Lymphocyte Activity in Sydney Blood Bank Cohort Patients Infected with nef-Defective HIV Type 1. Journal of Virology, 73(1), 436-443.
Ogg GS, Jin X, Bonhoeffer S, Moss P, Nowak MA, Monard S, Segal JP, Cao Y, Rowland-Jones SL, Hurley A , Markowitz M et al (1999) Decay Kinetics of Human Immunodeficiency Virus-Specific Effector Cytotoxic T Lymphocytes after Combination Antiretroviral Therapy. Journal of Virology, 73(1), 797-800.
Mear JP, Schreiber KL, Münz C, Zhu X, Stevanović S, Rammensee HG, Rowland-Jones SL & Colbert RA (1999) Misfolding of HLA-B27 as a result of its B pocket suggests a novel mechanism for its role in susceptibility to spondyloarthropathies. Journal of Immunology, 163(12), 6665-6670.
FOWKE KR, DONG TAO, ROWLAND-JONES SL, OYUGI J, RUTHERFORD WJ, KIMANI J, KRAUSA P, BWAYO JOB, SIMONSEN JN, SHEARER GM & PLUMMER FA (1998) HIV Type 1 Resistance in Kenyan Sex Workers Is Not Associated with Altered Cellular Susceptibility to HIV Type 1 Infection or Enhanced β-Chemokine Production. AIDS Research and Human Retroviruses, 14(17), 1521-1530.
Tan R, Wilson JD, Rostron T, Peto T, McMichael AJ & Rowland-Jones SL (1998) Prolonged CD8+ T-cell expansions after adoptive transfer of syngeneic lymphocytes between HIV-discordant identical twins [10]. AIDS, 12(16), 2240-2241.
Rowland-Jones SL, Dong T, Fowke KR, Kimani J, Krausa P, Newell H, Blanchard T, Ariyoshi K, Oyugi J, Ngugi E , Bwayo J et al (1998) Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi.. Journal of Clinical Investigation, 102(9), 1758-1765.
Ogg GS, Dong T, Hansasuta P, Dorrell L, Clarke J, Coker R, Luzzi G, Conlon C, McMichael AP & Rowland-Jones S (1998) Four novel cytotoxic T-lymphocyte epitopes in the highly conserved major homology region of HIV-1 Gag, restricted through B*4402, B*1801, A*2601, B*70 (B*1509). AIDS, 12(12), 1561-1563.
Wilson JDK, Ogg GS, Allen RL, Goulder PJR, Kelleher A, Sewell AK, O'Callaghan CA, Rowland-Jones SL, Callan MFC & McMichael AJ (1998) Oligoclonal Expansions of CD8+ T Cells in Chronic HIV Infection Are Antigen Specific. Journal of Experimental Medicine, 188(4), 785-790.
Whittle HC, Ariyoshi K & Rowland-Jones S (1998) HIV-2 and T cell recognition. Current Opinion in Immunology, 10(4), 382-387.
Rowland-Jones S, Colbert RA, Dong T, McAdam S, Brown M, Ariyoshi K, Sabally S, Whittle H & McMichael A (1998) Distinct recognition of closely-related HIV-1 and HIV-2 cytotoxic T-cell epitopes presented by HLA-B*2703 and B*2705. AIDS, 12(11), 1391-1393.
Anzala AO, Ball TB, Rostron T, Os'Brien SJ, Plummer FA & Rowland-Jones SL (1998) CCR2-64I allele and genotype association with delayed AIDS progression in African women. The Lancet, 351(9116), 1632-1633.
Price DA, Sewell AK, Dong T, Tan R, Goulder PJR, Rowland-Jones SL & Phillips RE (1998) Antigen–specific release of β-chemokines by anti-HIV-1 cytotoxic T lymphocytes. Current Biology, 8(6), 355-358.
Bertoletti A, Cham F, McAdam S, Rostron T, Rowland-Jones S, Sabally S, Corrah T, Ariyoshi K & Whittle H (1998) Cytotoxic T Cells from Human Immunodeficiency Virus Type 2-Infected Patients Frequently Cross-React with Different Human Immunodeficiency Virus Type 1 Clades. Journal of Virology, 72(3), 2439-2448.
Rowland-Jones SL (1998) Survival with HIV infection: good luck or good breeding?. Trends in Genetics, 14(9), 343-345.
Ogg GS (1998) Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA. Science, 279(5359), 2103-2106.
Rowland-Jones S, Dong T, Krausa P, Sutton J, Newell H, Ariyoshi K, Gotch F, Sabally S, Corrah T, Kimani J , MacDonald K et al (1998) The role of cytotoxic T-cells in HIV infection.. Developments in biological standardization, 92, 209-214.
Rowland-Jones S & Tan R (1997) Control of HIV co-receptor expression: Implications for pathogenesis and treatment. Trends in Microbiology, 5(8), 300-302.
Blanchard T, Alcamí A, Becker M, Hanke T, Andrea P, Gould K, Symonds JA, Britton W, Anderton P, Rowland-Jones S , McMichael AJ et al (1997) Vaccinia virus strain modified virus Ankara: Characterisation of cytokine receptor profile, virological features, and use as an immunological reagent. Immunology Letters, 56, 21-21.
Goulder PJR, Phillips RE, Colbert RA, McAdam S, Ogg G, Giangrande P, Luzzi G, Morgan B, Edwards A, McMichael A & Rowland-Jones S (1997) Late escape from an immunodominant cytotoxic T lymphocyte response associated with progression to AIDS. Immunology Letters, 56, 25-25.
Rowland-Jones S (1997) Dimers are a girl's best friend. Nature Medicine, 3(11), 1199-1200.
Rowland-Jones S, Tan R & McMichael A (1997) Role of Cellular Immunity in Protection against HIV Infection**This article was accepted for publication on 31 October 1996., 277-346.
Lalvani A, Dong T, Ogg G, Pathan AA, Newell H, Hill AVS, McMichael AJ & Rowland-Jones S (1997) Optimization of a peptide-based protocol employing IL-7 for in vitro restimulation of human cytotoxic T lymphocyte precursors. Journal of Immunological Methods, 210(1), 65-77.
Goulder PJR, Phillips RE, Colbert RA, McAdam S, Ogg G, Nowak MA, Giangrande P, Luzzi G, Morgana B, Edwards A , McMichael AJ et al (1997) Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS. Nature Medicine, 3(2), 212-217.
Goulder P, Price D, Nowak M, Rowland-Jones S, Phillips R & McMichael A (1997) Co-evolution of human immunodeficiency virus and cytotoxic T-lymphocyte responses. Immunological Reviews, 159(1), 17-29.
Griffin TA, Yuan J, Friede T, Stevanovic S, Ariyoshi K, Rowland-Jones SL, Rammensee HG & Colbert RA (1997) Naturally Occurring A Pocket Polymorphism in HLA-B*2703 Increases the Dependence on an Accessory Anchor Residue at P1 for Optimal Binding of Nonamer Peptides. Journal of Immunology, 159(10), 4887-4897.
Blanchard T, Rowland-Jones S, Gotch F, McMichael A & Smith GL (1996) Future vaccines for HIV. The Lancet, 348(9043), 1741-1741.
Dong T, Boyd D, Rosenberg W, Alp N, Takiguchi M, McMichael A & Rowland-Jones S (1996) An HLA-B35-restricted epitope modified at an anchor residue results in an antagonist peptide. European Journal of Immunology, 26(2), 335-339.
Moss PA, Rowland-Jones SL, Frodsham PM, McAdam S, Giangrande P, McMichael AJ & Bell JI (1995) Persistent high frequency of human immunodeficiency virus-specific cytotoxic T cells in peripheral blood of infected donors.. Proceedings of the National Academy of Sciences, 92(13), 5773-5777.
Lalloo D, Klenerman P, McAdam S, Köppe B, Rowland-Jones S, Phillips R & McMichael A (1995) Immune Escape in Hiv Infection. Clinical Science, 88(s32), 31P-31P.
Rowland-Jones S, Sutton J, Ariyoshi K, Dong T, Gotch F, McAdam S, Whitby D, Sabally S, Gallimore A, Corrah T , Takiguchi M et al (1995) HIV-specific cytotoxic T-cells in HIV-exposed but uninfected Gambian women. Nature Medicine, 1(1), 59-64.
Rowland-Jones S, Sutton J, Ariyoshi K, Dong T, Gotch F, McAdam S, Whitby D, Sabally S, Gallimore A, Corrah T , Takiguchi M et al (1995) Erratum: HIV-specific cytotoxic T-cells in HIV-exposed but uninfected Gambian women (Nature Medicine 1, 59-64, (1995)). Nature Medicine, 1(6), 598.
Rowland-Jones S (1995) Immune responses in HIV-exposed seronegatives: have they repelled the virus?. Current Opinion in Immunology, 7(4), 448-455.
Tussey LG, Rowland-Jones S, Zheng TS, Androlewicz MJ, Cresswell P, Frelinger JA & McMichael AJ (1995) Different MHC class I alleles compete for presentation of overlapping viral epitopes. Immunity, 3(1), 65-77.
McAdam S, Klenerman P, Tussey L, Rowland-Jones S, Lalloo D, Phillips R, Edwards A, Giangrande P, Brown AL, Gotch F & McMichael A (1995) Immunogenic HIV variant peptides that bind to HLA-B8 can fail to stimulate cytotoxic T lymphocyte responses. Journal of Immunology, 155(5), 2729-2736.
Nowak MA, May RM, Phillips RE, Rowland-Jones S, Lalloo DG, McAdam S, Klenerman P, Köppe B, Sigmund K, Bangham CRM & McMichael AJ (1995) Antigenic oscillations and shifting immunodominance in HIV-1 infections. Nature, 375(6532), 606-611.
Barouch D, Friede T, Stevanović S, Tussey L, Smith K, Rowland-Jones S, Braud V, McMichael A & Rammensee HG (1995) HLA-A2 subtypes are functionally distinct in peptide binding and presentation.. The Journal of Experimental Medicine, 182(6), 1847-1856.
McMichael A, Klenerman P, Rowland-Jones S, Gotch F & Moss P (1994) Recognition of viral antigens at the cell surface. Cancer Surveys, 22, 51-62.
McMichael A, Tussey L, Rowland-Jones S, Bowness P, Callan M & Gotch F (1994) T cell recognition of peptides bound to class I HLA molecules. Pathophysiology, 1, 75-75.
Warburton RJ, Matsui M, Rowland-Jones SL, Gammon MC, Katzenstein GE, Wei T, Edidin M, Zweerink HJ, McMichael AJ & Frelinger JA (1994) Mutation of the α2 domain disulfide bridge of the class I molecule HLA-A∗0201 Effect on maturation and peptide presentation. Human Immunology, 39(4), 261-271.
Tussey LG, Matsui M, Rowland-Jones S, Warburton R, Frelinger JA & McMichael A (1994) Analysis of mutant HLA-A2 molecules: Differential effects on peptide binding and CTL recognition. Journal of Immunology, 152(3), 1213-1221.
Klenerman P, Rowland-Jones S, McAdam S, Edwards J, Daenke S, Lalloo D, Köppe B, Rosenberg W, Boyd D, Edwards A , Giangrande P et al (1994) Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variants. Nature, 369(6479), 403-407.
Colbert RA, Rowland-Jones SL, McMichael AJ & Frelinger JA (1994) Differences in peptide presentation between B27 subtypes: The importance of the P1 side chain in maintaining high affinity peptide binding to B★2703. Immunity, 1(2), 121-130.
Rowland-Jones SL, Powis SH, Sutton J, Mockridge I, Gotch FM, Murray N, Hill AB, Rosenberg WM, Trowsdale J & McMichael AJ (1993) An antigen processing polymorphism revealed by HLA-B8-restricted cytotoxic T lymphocytes which does not correlate with TAP gene polymorphism. European Journal of Immunology, 23(8), 1999-2004.
Colbert RA, Rowland-Jones SL, McMichael AJ & Frelinger JA (1993) Allele-specific B pocket transplant in class I major histocompatibility complex protein changes requirement for anchor residue at P2 of peptide.. Proceedings of the National Academy of Sciences, 90(14), 6879-6883.
Rowland-Jones SL, Nixon DF, Gotch F, McMichael A, Kroll JS, Hallam N, Aldhous MC, Froebel K & Ariyoshi K (1993) HIV-specific cytotoxic T-cell activity in an HIV-exposed but uninfected infant. The Lancet, 341(8849), 860-861.
Rowland-Jones S & McMichael A (1993) Cytotoxic T lymphocytes in HIV infection. Seminars in Virology, 4(2), 83-94.
Gao XM, Tite JP, Lipscombe M, Rowland-Jones S, Ferguson DJ & McMichael AJ (1992) Recombinant Salmonella typhimurium strains that invade nonphagocytic cells are resistant to recognition by antigen-specific cytotoxic T lymphocytes.. Infection and Immunity, 60(9), 3780-3789.
ROWLAND-JONES SL, PHILLIPS RE, NIXON DF, GOTCH FM, EDWARDS JP, OGUNLESI AO, ELVIN JG, ROTHBARD JA, BANGHAM CRM, RIZZA CR & McMICHAEL AJ (1992) Human Immunodeficiency Virus Variants That Escape Cytotoxic T-Cell Recognition. AIDS Research and Human Retroviruses, 8(8), 1353-1354.
Pazmany L, Rowland-Jones S, Huet S, Hill A, Sutton J, Murray R, Brooks J & McMichael A (1992) Genetic modulation of antigen presentation by HLA-B27 molecules.. The Journal of Experimental Medicine, 175(2), 361-369.
Phillips RE, Rowland-Jones S, Nixon DF, Gotch FM, Edwards JP, Ogunlesi AO, Elvin JG, Rothbard JA, Bangham CRM, Rizza CR & McMichael AJ (1991) Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition. Nature, 354(6353), 453-459.
Moss PA, Moots RJ, Rosenberg WM, Rowland-Jones SJ, Bodmer HC, McMichael AJ & Bell JI (1991) Extensive conservation of alpha and beta chains of the human T-cell antigen receptor recognizing HLA-A2 and influenza A matrix peptide.. Proceedings of the National Academy of Sciences, 88(20), 8987-8990.
Thomas MG, Rowland-Jones S & Smyth E (1989) Klebsiella Pneumoniae Endocarditis. Journal of the Royal Society of Medicine, 82(2), 114-115.
Kuse N, Murakoshi H, Akahoshi T, Chikata T, James KL, Gatanaga H, Rowland-Jones SL, Oka S & Takiguchi M () Collaboration of a detrimental HLA-B*35:01 allele with HLA-A*24:02 in co-evolution of HIV-1 with T-cells leading to poorer clinical outcomes. Journal of Virology.
Moysi E, Darko S, Gea‐Mallorquí E, Petrovas C, Almeida JR, Wolinsky D, Peng Y, Jaye A, Stewart‐Jones G, Douek DC , Koup RA et al () Clonotypic architecture of a Gag‐specific CD8+ T‐cell response in chronic human HIV‐2 infection. European Journal of Immunology.
Ferrand RA, McHugh G, Rehman AM, Mujuru H, Simms V, Majonga ED, Nicol MP, Flaegstad T, Gutteberg TJ, Gonzalez-Martinez C , Corbett EL et al () Effect of Once-Weekly Azithromycin vs Placebo in Children With HIV-Associated Chronic Lung Disease. JAMA Network Open, 3(12), e2028484-e2028484.
Hameiri Bowen D, Sovershaeva E, Charlton B, Schive C, Odland J, McHugh G, Bandason T, Mayini J, Ferrand RA, Yindom L-M & Rowland-Jones SL () Cytomegalovirus-Specific Immunoglobulin G is associated with chronic lung disease in children and adolescents from sub-Saharan Africa with perinatal HIV infection. Clinical Infectious Diseases.
Ajaykumar A, Wong GC, Yindom L-M, McHugh G, Dauya E, Majonga E, Mujuru H, Ferrand RA, Rowland-Jones SL & Côté HCF () Shorter granulocyte telomeres among children and adolescents with perinatally-acquired HIV infection and chronic lung disease in Zimbabwe. Clinical Infectious Diseases.
Cox M, Adetifa JU, Noho-Konteh F, Sanyang LC, Drammeh A, Plebanski M, Whittle HC, Rowland-Jones SL, Robertson I & Flanagan KL () Sex-Differential Impact of Human Cytomegalovirus Infection on In Vitro Reactivity to Toll-Like Receptor 2, 4 and 7/8 Stimulation in Gambian Infants. Vaccines, 8(3), 407-407.
Cox M, Adetifa JU, Noho-Konteh F, Njie-Jobe J, Sanyang LC, Drammeh A, Plebanski M, Whittle HC, Rowland-Jones SL, Robertson I & Flanagan KL () Limited Impact of Human Cytomegalovirus Infection in African Infants on Vaccine-Specific Responses Following Diphtheria-Tetanus-Pertussis and Measles Vaccination. Frontiers in Immunology, 11.
Kim DS, Rowland-Jones S & Gea-Mallorquí E () Will SARS-CoV-2 Infection Elicit Long-Lasting Protective or Sterilising Immunity? Implications for Vaccine Strategies (2020). Frontiers in Immunology, 11.
Mhandire D, Rowland-Jones S, Mhandire K, Kaba M & Dandara C () Epidemiology of Cytomegalovirus among pregnant women in Africa. The Journal of Infection in Developing Countries, 13(10), 865-876.
Rowland-Jones S, Yindom L-M & Ferrand R () Reply to Cevik et al. Clinical Infectious Diseases.
Rylance S, Rylance J, McHugh G, Majonga E, Bandason T, Mujuru H, Nathoo K, Rowland-Jones S, Henrion MYR, Simms V & Ferrand RA () Effect of antiretroviral therapy on longitudinal lung function trends in older children and adolescents with HIV-infection. PLOS ONE, 14(3), e0213556-e0213556.
Mhandire K, Tshabalala M, Zijenah LS, Mlambo T, Mhandire DZ, Musarurwa C, Duri K, Matarira HT, Dandara C, Rowland-Jones SL & Stray-Pedersen B () HLA-C*18:01 and KIR2DL2+C1 genetic variants are associated with low viral load in cART naïve HIV-infected adult Zimbabweans. The Journal of Infection in Developing Countries, 12(12), 1105-1111.
Wang L, Zhang Y, Xu K, Dong T, Rowland-Jones S & Yindom L-M () Killer-cell immunoglobulin-like receptors associate with HIV-1 infection in a narrow-source Han Chinese cohort. PLOS ONE, 13(4), e0195452-e0195452.
Weatherley DAV, Boswell MT & Rowland-Jones SL () Targeting TRIM5α in HIV Cure Strategies for the CRISPR-Cas9 Era. Frontiers in Immunology, 8.
Yindom L-M, Mendy M, Bodimeade C, Chambion C, Aka P, Whittle HC, Rowland-Jones SL & Walton R () KIR content genotypes associate with carriage of hepatitis B surface antigen, e antigen and HBV viral load in Gambians. PLOS ONE, 12(11), e0188307-e0188307.
Goetghebuer T, Rowland-Jones SL & Kollmann TR () Editorial: Immune Mechanisms Underlying the Increased Morbidity and Mortality of HIV-Exposed Uninfected (HEU) Children. Frontiers in Immunology, 8.
Ndure J, Noho-Konteh F, Adetifa JU, Cox M, Barker F, Le MT, Sanyang LC, Drammeh A, Whittle HC, Clarke E , Plebanski M et al () Negative Correlation between Circulating CD4+FOXP3+CD127− Regulatory T Cells and Subsequent Antibody Responses to Infant Measles Vaccine but Not Diphtheria–Tetanus–Pertussis Vaccine Implies a Regulatory Role. Frontiers in Immunology, 8.
Andrews SM & Rowland-Jones S () Recent advances in understanding HIV evolution. F1000Research, 6, 597-597.
Noho-Konteh F, Adetifa JU, Cox M, Hossin S, Reynolds J, Le MT, Sanyang LC, Drammeh A, Plebanski M, Forster T , Dickinson P et al () Sex-Differential Non-Vaccine-Specific Immunological Effects of Diphtheria-Tetanus-Pertussis and Measles Vaccination. Clinical Infectious Diseases, ciw492-ciw492.
Zhang Y-H, Zhao Y, Rajapaksa US, Lawrence TM, Peng Y-C, Liu J, Xu K, Hu K, Qin L, Liu N , Sun H et al () A Comprehensive Analysis of the Impact of HIV on HCV Immune Responses and Its Association with Liver Disease Progression in a Unique Plasma Donor Cohort. PLOS ONE, 11(7), e0158037-e0158037.
Filteau S & Rowland-Jones S () Cytomegalovirus Infection May Contribute to the Reduced Immune Function, Growth, Development, and Health of HIV-Exposed, Uninfected African Children. Frontiers in Immunology, 7.
Garcia-Knight MA, Nduati E, Hassan AS, Gambo F, Odera D, Etyang TJ, Hajj NJ, Berkley JA, Urban BC & Rowland-Jones SL () Altered Memory T-Cell Responses to Bacillus Calmette-Guerin and Tetanus Toxoid Vaccination and Altered Cytokine Responses to Polyclonal Stimulation in HIV-Exposed Uninfected Kenyan Infants. PLOS ONE, 10(11), e0143043-e0143043.
Tansiri Y, Rowland-Jones SL, Ananworanich J & Hansasuta P () Clinical Outcome of HIV Viraemic Controllers and Noncontrollers with Normal CD4 Counts Is Exclusively Determined by Antigen-Specific CD8+ T-Cell-Mediated HIV Suppression. PLOS ONE, 10(3), e0118871-e0118871.
Abidi SH, Kalish ML, Abbas F, Rowland-Jones S & Ali S () HIV-1 Subtype A Gag Variability and Epitope Evolution. PLoS ONE, 9(6), e93415-e93415.
Rafferty H, Sibeko S & Rowland-Jones S () How can we design better vaccines to prevent HIV infection in women?. Frontiers in Microbiology, 5.
Afolabi MO, Ndure J, Drammeh A, Darboe F, Mehedi S-R, Rowland-Jones SL, Borthwick N, Black A, Ambler G, John-Stewart GC , Reilly M et al () A Phase I Randomized Clinical Trial of Candidate Human Immunodeficiency Virus type 1 Vaccine MVA.HIVA Administered to Gambian Infants. PLoS ONE, 8(10), e78289-e78289.
Powell TJ, Peng Y, Berthoud TK, Blais M-E, Lillie PJ, Hill AVS, Rowland-Jones SL, McMichael AJ, Gilbert SC & Dong T () Examination of Influenza Specific T Cell Responses after Influenza Virus Challenge in Individuals Vaccinated with MVA-NP+M1 Vaccine. PLoS ONE, 8(5), e62778-e62778.
Nyamweya S, Townend J, Zaman A, Steele SJ, Jeffries D, Rowland-Jones S, Whittle H, Flanagan KL & Jaye A () Are Plasma Biomarkers of Immune Activation Predictive of HIV Progression: A Longitudinal Comparison and Analyses in HIV-1 and HIV-2 Infections?. PLoS ONE, 7(9), e44411-e44411.
Walther M, De Caul A, Aka P, Njie M, Amambua-Ngwa A, Walther B, Predazzi IM, Cunnington A, Deininger S, Takem EN , Ebonyi A et al () HMOX1 Gene Promoter Alleles and High HO-1 Levels Are Associated with Severe Malaria in Gambian Children. PLoS Pathogens, 8(3), e1002579-e1002579.
Slyker JA, Lohman-Payne B, John-Stewart GC, Dong T, Mbori-Ngacha D, Tapia K, Atzberger A, Taylor S, Rowland-Jones SL & Blish CA () The impact of HIV-1 infection and exposure on natural killer (NK) cell phenotype in Kenyan infants during the first year of life. Frontiers in Immunology, 3.
Simpson PD, Moysi E, Wicks K, Sudan K, Rowland-Jones SL, McMichael AJ, Knight J & Gillespie GM () Functional Differences Exist between TNFα Promoters Encoding the Common −237G SNP and the Rarer HLA-B*5701-Linked A Variant. PLoS ONE, 7(7), e40100-e40100.
Jayasooriya S, Hislop A, Peng Y, Croom-carter D, Jankey Y, Bell A, Dong T, Rowland-Jones S, Rickinson A, Walther M & Whittle H () Revisiting the Effect of Acute P. falciparum Malaria on Epstein-Barr Virus: Host Balance in the Setting of Reduced Malaria Endemicity. PLoS ONE, 7(2), e31142-e31142.
Buranapraditkun S, Hempel U, Pitakpolrat P, Allgaier RL, Thantivorasit P, Lorenzen S-I, Sirivichayakul S, Hildebrand WH, Altfeld M, Brander C , Walker BD et al () A Novel Immunodominant CD8+ T Cell Response Restricted by a Common HLA-C Allele Targets a Conserved Region of Gag HIV-1 Clade CRF01_AE Infected Thais. PLoS ONE, 6(8), e23603-e23603.
Ranasinghe SRF, Kramer HB, Wright C, Kessler BM, di Gleria K, Zhang Y, Gillespie GM, Blais M-E, Culshaw A, Pichulik T , Simmons A et al () The Antiviral Efficacy of HIV-Specific CD8+ T-Cells to a Conserved Epitope Is Heavily Dependent on the Infecting HIV-1 Isolate. PLoS Pathogens, 7(5), e1001341-e1001341.
Slyker JA, John-Stewart GC, Dong T, Lohman-Payne B, Reilly M, Atzberger A, Taylor S, Maleche-Obimbo E, Mbori-Ngacha D & Rowland-Jones SL () Phenotypic Characterization of HIV-Specific CD8+ T Cells during Early and Chronic Infant HIV-1 Infection. PLoS ONE, 6(5), e20375-e20375.
Holder B, Miles DJC, Kaye S, Crozier S, Mohammed NI, Duah NO, Roberts E, Ojuola O, Palmero MS, Touray ES , Waight P et al () Epstein-Barr Virus but Not Cytomegalovirus Is Associated with Reduced Vaccine Antibody Responses in Gambian Infants. PLoS ONE, 5(11), e14013-e14013.
Burl S, Adetifa UJ, Cox M, Touray E, Whittle H, McShane H, Rowland-Jones SL & Flanagan KL () The Tuberculin Skin Test (TST) Is Affected by Recent BCG Vaccination but Not by Exposure to Non-Tuberculosis Mycobacteria (NTM) during Early Life. PLoS ONE, 5(8), e12287-e12287.
Miles DJC, van der Sande M, Jeffries D, Kaye S, Ojuola O, Sanneh M, Cox M, Palmero MS, Touray ES, Waight P , Rowland-Jones S et al () Maintenance of Large Subpopulations of Differentiated CD8 T-Cells Two Years after Cytomegalovirus Infection in Gambian Infants. PLoS ONE, 3(8), e2905-e2905.
Voelter V, Rufer N, Reynard S, Greub G, Brookes R, Guillaume P, Grosjean F, Fagerberg T, Michelin O, Rowland-Jones S , Pinilla C et al () Characterization of Melan-A reactive memory CD8+ T cells in a healthy donor. International Immunology, 20(8), 1087-1096.
Rowland-Jones S & de Silva T () Correction: Resisting Immune Exhaustion in HIV-1 Infection. PLoS Medicine, 5(6), e134-e134.
Lee LY-H, Ha DLA, Simmons C, de Jong MD, Chau NVV, Schumacher R, Peng YC, McMichael AJ, Farrar JJ, Smith GL , Townsend ARM et al () Memory T cells established by seasonal human influenza A infection cross-react with avian influenza A (H5N1) in healthy individuals. Journal of Clinical Investigation.
van der Sande MAB, Kaye S, Miles DJC, Waight P, Jeffries DJ, Ojuola OO, Palmero M, Pinder M, Ismaili J, Flanagan KL , Aveika AA et al () Risk Factors for and Clinical Outcome of Congenital Cytomegalovirus Infection in a Peri-Urban West-African Birth Cohort. PLoS ONE, 2(6), e492-e492.
Dong T, Moran E, Vinh Chau N, Simmons C, Luhn K, Peng Y, Wills B, Phuong Dung N, Thi Thu Thao L, Hien TT , McMichael A et al () High Pro-Inflammatory Cytokine Secretion and Loss of High Avidity Cross-Reactive Cytotoxic T-Cells during the Course of Secondary Dengue Virus Infection. PLoS ONE, 2(12), e1192-e1192.
Papagno L, Spina CA, Marchant A, Salio M, Rufer N, Little S, Dong T, Chesney G, Waters A, Easterbrook P , Dunbar PR et al () Immune Activation and CD8+ T-Cell Differentiation towards Senescence in HIV-1 Infection. PLoS Biology, 2(2), e20-e20.
Darboe F, Adetifa JU, Reynolds J, Hossin S, Plebanski M, Netea MG, Rowland-Jones SL, Sutherland JS & Flanagan KL () Minimal Sex-Differential Modulation of Reactivity to Pathogens and Toll-Like Receptor Ligands following Infant Bacillus Calmette–Guérin Russia Vaccination. Frontiers in Immunology, 8.
Palm AA, Lemey P, Jansson M, Månsson F, Kvist A, Szojka Z, Biague A, da Silva ZJ, Rowland-Jones SL, Norrgren H , Esbjörnsson J et al () Low Postseroconversion CD4+T-cell Level Is Associated with Faster Disease Progression and Higher Viral Evolutionary Rate in HIV-2 Infection. mBio, 10(1).

Chapters

Andrews SM, Wong G & Rowland-Jones SL (2018) Cellular Immune Response to HIV-2 Infection, Encyclopedia of AIDS (pp. 259-268). Springer New York
Suchindran S & Triant VA (2018) Cardiovascular Complications, Encyclopedia of AIDS (pp. 219-224). Springer New York
Andrews SM, Wong G & Rowland-Jones SL (2015) The Cellular Immune Response to HIV-2 Infection, Encyclopedia of AIDS (pp. 1-10). Springer New York
Ball TB, Barré-Sinoussi F, Biasin M, Blankson JN, Broliden K, Buckheit RW, Card CM, Clerici M, de Silva T, Fellay J , Fowke KR et al (2012) Contributors, Models of Protection Against HIV/SIV (pp. xi-xii). Elsevier
Moysi E, de Silva T & Rowland-Jones S (2012) Chapter 11 Immune Mechanisms of Viral Control in HIV-2 Infection, Models of Protection Against HIV/SIV (pp. 293-315).
Moysi E, de Silva T & Rowland-Jones S (2012) Immune Mechanisms of Viral Control in HIV-2 Infection, Models of Protection Against HIV/SIV (pp. 293-315). Elsevier
Zumla A, Rowland-Jones S & McMichael A (1997) Lung Immunology and HIV, AIDS and Respiratory Medicine (pp. 15-40). Springer US

Conference proceedings papers

Murakoshi H, Akahoshi T, Koyanagi M, Chikata T, James KL, Tamura Y, Kuse N, Sun X, Gatanaga H, Rowland-Jones SL , Oka S et al (2016) Impaired Effect of HLA-A*24: 02-associated Mutation on HLA-B*35: 01-associated HIV-1 Control. AIDS RESEARCH AND HUMAN RETROVIRUSES, Vol. 32 (pp 168-168)
Wang L, Yindom LM, Zhang Y, Xu K, Yan H, Dong T & Rowland-Jones SL (2014) Killer-cell immunoglobulin-like receptor (KIR) genetic diversity in a unique HIV-1 cohort in China. IMMUNOLOGY, Vol. 143 (pp 157-157)
Yindom LM, Wang L, Zhang Y, Xu KY, Yan H, Dong T & Rowland-Jones SL (2011) Killer-cell immunoglobulin-like receptor (KIR) genetic diversity in a unique HIV-1 cohort in China. IMMUNOLOGY, Vol. 135 (pp 168-168)
Dong T, Zhang Y, Xu KY, Yan H, James I, Peng Y, Blais M-E, Gaudieri S, Chen X, Lun W , Wu H et al (2011) Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China. Blood, Vol. 118(1) (pp 98-106)
Culshaw A, Zhang YH, Yan H, Xu K, Rowland-Jones SL & Dong T (2010) Characterisation of immune responses within HLA-B*40+patients in a Chinese HIV-1 infected slow progressor cohort. IMMUNOLOGY, Vol. 131 (pp 165-165)
Powell TJ, Fox A, Lien VTK, Hang NLK, Mai LTQ, McMichael AJ, Rowland-Jones SL, Horby P & Dong T (2010) Analysis of H5N1 specific T cell responses in a high risk cohort in VietNam indicates possible asymptomatic infection. IMMUNOLOGY, Vol. 131 (pp 149-149)
Nuvor SV, Rowland-jones S, Whittle H & Jaye A (2010) Comparison of Cytotoxic activity and Interferon-g secretion by Natural Killer Cells in HIV-1 and HIV-2 infected individuals. Retrovirology, Vol. 7(S1)
Onyango C, Leligdowicz A, Yokoyama M, Sato H, Song H, Nakayama E, Shioda T, Jaye A, Whittle H, Rowland-Jones S & Cotten M (2009) 139 HIV-2 Capsids Distinguishing High and Low Virus Load Patients in a West African Community Cohort. JAIDS Journal of Acquired Immune Deficiency Syndromes, Vol. 51 (pp 1-1)
Culshaw A, Mashishi T, Spina C, Richman DD, Dong T & Rowland-Jones SL (2008) CTL responses to HIV-1 during acute and chronic infection. IMMUNOLOGY, Vol. 125 (pp 115-115)
Kemal KS, Beattie T, Dong T, Weiser B, Kaul R, Kuiken C, Sutton J, Lang D, Yang H, Peng YC , Collman R et al (2008) Transition From Long-Term Nonprogression to HIV-1 Disease Associated With Escape From Cellular Immune Control. JAIDS Journal of Acquired Immune Deficiency Syndromes, Vol. 48(2) (pp 119-126)
Mackelprang RD, John‐Stewart G, Carrington M, Richardson B, Rowland‐Jones S, Gao X, Mbori‐Ngacha D, Mabuka J, Lohman‐Payne B & Farquhar C (2008) Maternal HLA Homozygosity and Mother‐Child HLA Concordance Increase the Risk of Vertical Transmission of HIV‐1. The Journal of Infectious Diseases, Vol. 197(8) (pp 1156-1161)
Ondondo B, Yang H, Dong T, Gleria KD, Suttill A, Conlon C, Brown D, Williams P, Bowness P, Rowland-Jones SL , Hanke T et al (2006) Detection of broad functional gag-specific CD4+ T cell responses in HIV-1-infected subjects following therapeutic immunization with rMVA expressing an HIV-1 gag immunogen. Retrovirology, Vol. 3(S1)
Leligdowicz A, Yindom L-M, Jaye A, Dong T, Alabi A, Sarge-N'jie R, Njai H, McMichael A, Whittle H & Rowland-Jones S (2006) HIV-2 gene product-specific T cell responses and viraemia control. Retrovirology, Vol. 3(S1)
Ranasinghe SR, Abidi SH, Rowland-Jones SL, McMichael AJ, Dong T & Davis SJ (2005) Functional analysis of candidate CD8+T cell-derived anti-HIV factors. IMMUNOLOGY, Vol. 116 (pp 80-80)
Ondondo BO, Yang H, Rowland-Jones SL, Hanke T, McMichael A & Dorrell L (2005) pTHr.HIVA and MVA.HIVA vaccines (gag p24/p17) augment CD4+T cell responses in chronically infected HIV-1 patients on HAART. IMMUNOLOGY, Vol. 116 (pp 108-108)
Slyker JA, Lohman BL, Mbori-Ngacha DA, Reilly M, Wee EG-T, Dong T, McMichael AJ, Rowland-Jones SL, Hanke T & John-Stewart G (2005) Modified vaccinia Ankara expressing HIVA antigen stimulates HIV-1-specific CD8 T cells in ELISpot assays of HIV-1 exposed infants. Vaccine, Vol. 23(38) (pp 4711-4719)
Abidi SH, Dong T, Hene L, Vuong M, Evans EJ, McMichael AJ, Rowland-Jones SL, Davis SJ & MEDIMOND (2004) Anti-CD8 antibody induced transcriptional remodelling in HIV-specific CD8 T cells secreting Anti-HIV-1 factors. XV INTERNATIONAL AIDS CONFERENCE: BASIC SCIENCE (pp 131-135)
MacDonald KS, Fowke KR, Kimani J, Dunand VA, Nagelkerke NJD, Ball TB, Oyugi J, Njagi E, Gaur LK, Brunham RC , Wade J et al (2000) Influence of HLA Supertypes on Susceptibility and Resistance to Human Immunodeficiency Virus Type 1 Infection. The Journal of Infectious Diseases, Vol. 181(5) (pp 1581-1589)
McMichael AJ, Ogg G, Wilson J, Callan M, Hambleton S, Appay V, Kelleher T & Rowland-Jones S (2000) Memory CD8+T cells in HIV infection. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, Vol. 355(1395) (pp 363-367)
Rowland-Jones S (1999) Broadly cross-reactive HIV-specific cytotoxic T-lymphocytes in highly-exposed persistently seronegative donors. Immunology Letters, Vol. 66(1-3) (pp 9-14)
McMichael A, Goulder P, Rowland-Jones S, Phillips R, Xu O & Screaton G (1997) Escafe from immune control by HIV. FASEB Journal, Vol. 11(9)

Teaching interests: I enjoy teaching and currently lecture on the M.Sc courses in Molecular Medicine (IICD) and Antimicrobial Resistance (Florey Institute). I am a Mentor on the Academy of Medical Sciences scheme for early career researchers on intermediate fellowships.

Professional activities

Co-coordinator (with Professor Simon Foster), Florey Institute for Host-Pathogen interactions
Theme Lead, Infection theme, IICD
Academic Editor, Public Library of Science (Biology), 2003 to present, Member of PLOS Biology Advisory Board from 2015 onwards
Member, Newton Advanced Fellowships panel, Royal Society, 2015 – present
Member, Swedish Research Council, Global Health Panel, 2016 – present
Member, Future Leaders African Independent Research (FLAIR) fellowship panel (Royal Society), 2018 – present
Member of the Faculty of 1000 since its inception in 2002 to present
Academy of Medical Sciences, member of Global Health group, from 2007
Academy of Medical Sciences, Fellowship committee (panel 4), from 2017 – present
External Examiner, Department of Pathology, University of Zimbabwe College of Health Sciences, 2017 - present