Dr Ahmed Iqbal
BSc (Hons), MBBS (Hons), MRCP, PgCert, PhD
Department of Oncology and Metabolism
NIHR Academic Clinical Lecturer in Diabetes and Endocrinology
+44 114 215 9238
Full contact details
Department of Oncology and Metabolism
E Floor
The Medical School
Beech Hill Road
Sheffield
S10 2RX
- Profile
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For enquiries, please contact - om-operational@sheffield.ac.uk
My career goals are to develop as an academic physician in diabetes and endocrinology and to continually find ways to improve the lives of my patients.
I developed a passion for research during my intercalated BSc in the Medical Sciences with Haematology at Imperial College London. Following this, I completed my undergraduate training at Newcastle Medical School graduating with honours and was successful in obtaining a place on the Academic Foundation Programme in Endocrinology at the University of Bristol and University Hospitals Bristol. I then moved to Sheffield as a NIHR Academic Clinical Fellow (ACF) in Diabetes and Endocrinology.
Under joint supervision from Professors Heller, Francis and Sabroe and Dr Lynne Prince I was successful in obtaining a Medical Research Council (MRC) Clinical Research Training Fellowship to pursue a PhD at the University of Sheffield.
I am currently a NIHR Academic Clinical Lecturer and an Honorary Specialty Registrar at Sheffield Teaching Hospitals. My clinical interests are in managing hypoglycaemia and the use of novel technologies in the management of both type 1 and type 2 diabetes.
- Research interests
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I am interested in exploring mechanisms whereby hypoglycaemia might lead to progression of atherosclerosis and mortality, helping to explain why intensive glucose control in patients with type 2 diabetes has failed to reduce macrovascular disease.
Importantly, in addition to further dissection of mechanisms that underpin the relationship between hypoglycaemia and atherosclerosis, I want to conduct research to come up with novel therapeutic options that are urgently needed to mitigate the risk hypoglycaemia poses on the cardiovascular system in those with diabetes.Current projects
- Hypoglycaemia and Inflammation.
- Risk of cardiac arrhythmias and electrophysiological responses during spontaneous hypoglycaemia in people with type 1 diabetes.
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- A higher non-severe hypoglycaemia rate is associated with an increased risk of subsequent severe hypoglycaemia and major adverse cardiovascular events in individuals with type 2 diabetes in the LEADER study. Diabetologia.
- Effect of Hypoglycemia on Inflammatory Responses and the Response to Low Dose Endotoxemia in Humans.. Journal of Clinical Endocrinology and Metabolism, 104(4), 1187-1199. View this article in WRRO
- Prolonged Prothrombotic Effects of Antecedent Hypoglycemia in Individuals With Type 2 Diabetes. Diabetes Care, 41(12), 2625-2633. View this article in WRRO
- The role of structured education in the management of hypoglycaemia. Diabetologia. View this article in WRRO
- Home use of closed-loop insulin delivery for overnight glucose control in adults with type 1 diabetes: a 4-week, multicentre, randomised crossover study. The Lancet Diabetes & Endocrinology, 2(9), 701-709. View this article in WRRO
- A UK nationwide study of people with type 1 diabetes admitted to hospital with COVID-19 infection. Diabetologia.
All publications
Journal articles
- Hypertonic saline for severe symptomatic hyponatraemia: real-world findings from the UK.. Endocr Connect.
- Enhanced neutrophil extracellular trap formation in COVID-19 is inhibited by the PKC inhibitor ruboxistaurin. ERJ Open Research. View this article in WRRO
- A higher non-severe hypoglycaemia rate is associated with an increased risk of subsequent severe hypoglycaemia and major adverse cardiovascular events in individuals with type 2 diabetes in the LEADER study. Diabetologia.
- Cushing’s disease presenting with psychosis. Practical Neurology, 21(4), 351-353.
- Higher admission activated partial thromboplastin time, neutrophil-lymphocyte ratio, serum sodium, and anticoagulant use predict in-hospital COVID-19 mortality in people with Diabetes: Findings from Two University Hospitals in the U.K. Diabetes Research and Clinical Practice, 108955-108955.
- A bittersweet response to infection in diabetes ; targeting neutrophils to modify inflammation and improve host immunity. Frontiers in Immunology, 12.
- Cardiac arrhythmias and electrophysiologic responses during spontaneous hyperglycaemia in adults with type 1 diabetes mellitus. Diabetes & Metabolism, 101237-101237.
- Coronary Artery Spasm–Induced Cardiac Arrest Precipitated by Iodine Contrast Load in Unknown Pre-Existing Graves’ Disease. JACC: Cardiovascular Interventions, 13(16), e147-e149.
- Adrenal incidentaloma: cardiovascular and metabolic effects of mild cortisol excess. Gland Surgery, 9(1), 94-104.
- Therapy of mild cortisol excess. Current Opinion in Endocrine and Metabolic Research, 8, 183-188.
- Two cases of spontaneous remission of primary hyperparathyroidism due to auto-infarction : different management and their outcomes. Endocrinology Diabetes and Metabolism Case Reports, 2019(1). View this article in WRRO
- Effect of Hypoglycemia on Inflammatory Responses and the Response to Low Dose Endotoxemia in Humans.. Journal of Clinical Endocrinology and Metabolism, 104(4), 1187-1199. View this article in WRRO
- Prolonged Prothrombotic Effects of Antecedent Hypoglycemia in Individuals With Type 2 Diabetes. Diabetes Care, 41(12), 2625-2633. View this article in WRRO
- Salbutamol-induced electrophysiological changes show no correlation with electrophysiological changes during hyperinsulinaemic-hypoglycaemic clamp in young people with Type 1 diabetes.. Diabetic Medicine, 35(9), 1264-1272. View this article in WRRO
- Corrigendum: Recent updates on type 1 diabetes mellitus management for clinicians [Diabetes Metab J 2018;42:3-18] doi 10.4093/dmj.2018.42.1.3. Diabetes and Metabolism Journal, 42(2), 177-177. View this article in WRRO
- Recent updates on type 1 diabetes mellitus management for clinicians. Diabetes and Metabolism Journal, 42(1), 3-18. View this article in WRRO
- The role of structured education in the management of hypoglycaemia. Diabetologia. View this article in WRRO
- Diurnal Differences in Risk of Cardiac Arrhythmias During Spontaneous Hypoglycemia in Young People With Type 1 Diabetes. Diabetes Care, 40(5), 655-662. View this article in WRRO
- Managing hypoglycaemia. Best Practice & Research Clinical Endocrinology & Metabolism, 30(3), 413-430. View this article in WRRO
- Juvenile granulosa cell tumour of the ovary presenting with hyperprolactinaemic amenorrhoea and galactorrhoea. Endocrinology, Diabetes & Metabolism Case Reports, 2016. View this article in WRRO
- Factors Associated With Glycemic Control During Free-Living Overnight Closed-Loop Insulin Delivery in Children and Adults With Type 1 Diabetes. Journal of Diabetes Science and Technology, 9(6), 1346-1347. View this article in WRRO
- Unsupervised home use of an overnight closed-loop system over 3-4 weeks: A pooled analysis of randomized controlled studies in adults and adolescents with type 1 diabetes. Diabetes, Obesity and Metabolism, 17(5), 452-458. View this article in WRRO
- Psychosocial aspects of closed- and open-loop insulin delivery: closing the loop in adults with Type 1 diabetes in the home setting. Diabetic Medicine, 32(5), 601-608.
- TSH Levels and Risk of Miscarriage in Women on Long-Term Levothyroxine: A Community-Based Study. The Journal of Clinical Endocrinology & Metabolism, 99(10), 3895-3902.
- Home use of closed-loop insulin delivery for overnight glucose control in adults with type 1 diabetes: a 4-week, multicentre, randomised crossover study. The Lancet Diabetes & Endocrinology, 2(9), 701-709. View this article in WRRO
- Falling Threshold for Treatment of Borderline Elevated Thyrotropin Levels—Balancing Benefits and Risks. JAMA Internal Medicine, 174(1), 32-32.
- Hypertensive Emergency and Type 2 Myocardial Infarction Resulting From Pheochromocytoma and Concurrent Capnocytophaga Canimorsus Infection. The Open Cardiovascular Medicine Journal, 8(1), 43-47. View this article in WRRO
- Wegener's granulomatosis presenting with multiple cranial nerve palsies and pachymeningitis. Practical Neurology, 13(3), 193-195.
- A meta-analysis of the associations between common variation in the PDE8B gene and thyroid hormone parameters, including assessment of longitudinal stability of associations over time and effect of thyroid hormone replacement. European Journal of Endocrinology, 164(5), 773-780.
- The presence of a BCR-ABL mutant allele in CML does not always explain clinical resistance to imatinib. Leukemia, 20(4), 658-663.
- A UK nationwide study of people with type 1 diabetes admitted to hospital with COVID-19 infection. Diabetologia.
- View this article in WRRO
Chapters
- Clinical management of type 1 diabetes, Advanced Nutrition and Dietetics in Diabetes (pp. 60-66). John Wiley & Sons, Ltd
Conference proceedings papers
- SUN-299 Flash Glucose Sensor Monitoring for Patients with Endogenous Hyperinsulinaemic Hypoglycaemia. Journal of the Endocrine Society, Vol. 4(Supplement_1)
- 047 An unusual cause of psychosis. Journal of Neurology Neurosurgery & Psychiatry, Vol. 90(12) (pp a21)
- Unsupervised overnight closed loop insulin delivery during free living: analysis of randomised cross-over home studies in adults and adolescents with type 1 diabetes. The Lancet, Vol. 385 (pp S96-S96)
- Effect of hypoglycaemia on thrombosis and inflammation in patients with type 2 diabetes. The Lancet, Vol. 383 (pp S35-S35)
- I CANNOT SMILE, DOCTOR. Journal of Neurology, Neurosurgery & Psychiatry, Vol. 83(Suppl 2) (pp A24.2-A24)
- MULTIPLE CRANIAL NERVE PALSIES IN A YOUNG SINGER. Journal of Neurology, Neurosurgery & Psychiatry, Vol. 83(Suppl 2) (pp A18.1-A18)
- Functional or non-function pancreatic NET; Novel use of a flash glucose monitoring system. Endocrine Abstracts
- Four years of tolvaptan: experience from two large teaching hospitals. Endocrine Abstracts
- A higher non-severe hypoglycaemia rate is associated with an increased risk of subsequent severe hypoglycaemia and major adverse cardiovascular events in individuals with type 2 diabetes in the LEADER study. Diabetologia.
- Professional activities
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Undergraduate
- Foundation Clinical Skills Couse-Thyroid Teaching, MBChB programme, University of Sheffield.
Postgraduate
- MRCP (UK) PACES Examination, Royal College of Physicians, London, Host Registrar.
Committee Membership
- Diabetes and Cardiovascular Disease Study Group, European Association for the Study of Diabetes (EASD).
- UK-wide Diabetes Research Strategy Steering Group formed by NIHR and Diabetes UK.
Reviewer
- Diabetic Medicine.
- Journal of Endocrinological Investigation.
- International Journal of Endocrinology.
- Diabetes Research and Clinical Practice.
- Diabetes Obesity and Metabolism.
- Diabetes and Vascular Disease.
- Primary Care Diabetes.