Lizzie Swaby

Study Manager 

Clinical Trials Research Unit, ScHARR
The University of Sheffield
Regent Court
30 Regent Street
S1 4DA

Office: Room 2.11, Innovation Centre

Tel: +44 (0) 114 222 4023
Fax: +44 (0) 114 222 0870

Email :



I am currently the Study Manager for the ASTIClite trial, looking at autologous stem cell transplantation for refractory Crohn's Disease. The trial is currently in recruitment, with the first site opening in May 2018. I joined the Clinical Trials Research Unit as a Research Assistant in August 2014, and worked on a variety of different studies during that time.

Current projects

  • ASTIClite (Autologous Stem cell Transplantation In refractory Crohn's disease - Low Intensity Therapy Evaluation

Previous projects

  • HubBLe (Haemorrhoidal Artery Ligation (HAL) versus Rubber Band Ligation (RBL) for haemorrhoids)
  • PAINTED (Pandemic Influenza Triage in the Emergency Department)
  • PRACTICE (Pulmonary Rehabilitation and ACTivity in COPD Exacerbations)
  • OPTION-DM (Optimal Pathway for Treating Neuropathic Pain In Diabetes Mellitus)
  • STEPWISE (STructured lifestyle Education for People WIth Schizophrenia)


MSc Health Services Research, University of York

BSc (Hons) Pharmacology, University of Leeds


Beever D & Swaby L (2019) An evaluation of risk-based monitoring in pragmatic trials in UK Clinical Trials Units. Trials. 20: 556 DOI: 10.1186/s13063-019-3619-6

Swaby L, Holt RIG, Gossage-Worrall R & Hind D (2019) Provision of weight loss programmes and their influence on weight after one year: a follow up survey of usual care in the STEPWISE study. eLetters, BJPsych Bulletin; 2nd August 2019.

Snowden JA, Hawkey C, Hind D, Swaby L, Mellor K, Emsley R, Mandefield L, Lee E, Badoglio M, Polge E, Labopin M, Gribben J, Pockley AG, Foulds GA, Lobo A, Travis S, Parkes M, Satsangi J, Papaioannou D & Lindsay JO (2019) Autologous stem cell transplantation in refractory Crohn's disease - low intensity therapy evaluation (ASTIClite): study protocols for a multicentre, randomised controlled trial and observational follow up study. BMC Gastroenterology. 2019;19:82

Holt RIG, Hind D, Gossage-Worrall R, Bradburn MJ, Saxon D, McCrone P, Morris TA, Etherington A, Shiers D, Barnard K, Swaby L et al (2018) Structured lifestyle education to support weight loss for people with schizophrenia, schizoaffective disorder and first episode psychosis: the STEPWISE RCT. Health Technol Assess. 2018;22(65)

Selvarajah D, Petrie J, White D, Julious S, Bortolami O, Cooper C, Bradburn M, Loban A, Bowler H, Swaby L, Sutherland K, Tesfaye S, on behalf of the OPTION-DM group (2018) Multicentre, double-blind, crossover trial to identify the Optimal Pathway for TreatIng neurOpathic paiN in Diabetes Mellitus (OPTION-DM): study protocol for a randomised controlled trial. Trials. 19:578 DOI: 10.1186/s13063-018-2959-y

Holt RIG, Gossage-Worrall R, Hind D, Bradburn M, McCrone P, Morris T, Edwardson C, Barnard K, Carey ME, Davies MJ, Dickens CM, Doherty Y, Etherington A, French P, Gaughran F, Greenwood K, Kalidindi S, Khunti K, Laugharne R, Pendlebury J, Rathod S, Saxon D, Shiers D, Siddiqi N, Swaby E, Waller G & Wright S (2018) Structured lifestyle education for people with schizophrenia, schizoaffective disorder and first-episode psychosis (STEPWISE): randomised controlled trial. BJPsych, 1-11. DOI: 10.1192/bjp.2018.167

Swaby L, Hind D, Gossage-Worrall R, Shiers D, Mitchell J & Holt RIG (2016) Adherence to NICE guidance on lifestyle advice for people with schizophrenia: a survey. BJPsych Bulletin, Vol 40, Issue 6, DOI: 10.1192/pb.bp.116.054304 Published 10 November 2016

Brown S, Tiernan J, Biggs K, Hind D, Shephard N, Bradburn M, Wailoo A, Alshreef A, Swaby L, Watson A, Radley S, Jones O, Skaife P, Agarwal A, Giordano P, Lamah M, Cartmell M, Davies J, Faiz O, Nugent K, Clarke A, MacDonald A, Conaghan P, Ziprin P & Makhija R (2016) The HubBLe Trial: haemorrhoidal artery ligation (HAL) versus rubber band ligation (RBL) for symptomatic second and third degree haemorrhoids: a multicentre randomised controlled trial and health-economic evaluation. Health Technology Assessment Volume 20, Issue 88, Published in December 2016.

Gossage-Worrall R, Holt RIG, Barnard K, Carey ME, Davies MJ, Dickens C, Doherty Y, Edwardson C, French P, Gaughran F, Greenwood K, Kalidindi S, Hind D, Khunti K, McCrone P, Mitchell J, Pendlebury J, Rathod S, Shiers D, Siddiqi N, Swaby L & Wright S (2016) STEPWISE - STructured lifestyle Education for People WIth SchizophrEnia: a study protocol for a randomised controlled trial. Trials, 17(1), 475.

Brown SR, Tiernan JP, Watson AJ, Biggs K, Shephard N, Wailoo AJ, Bradburn M, Alshreef A, Hind D and HubBLe Study Team (2016) Haemorrhoidal artery ligation versus rubber band ligation for the management of symptomatic second-degree and third-degree haemorrhoids (HubBLe): a multicentre, open-label, randomised controlled trial. The Lancet. 2016 388:356-364. DOI:

Conference Publications

Gossage-Worrall R, Swaby L, Hind D & Holt RIG STructured lifestyle Education for People WIth SchizophrEnia (STEPWISE): Rationale, design and baseline data. i-Poster presented at: Royal College of Psychiatrists International Congress 2016; 27-30 June 2016, London

Athavale NV, Thompson K, Franke B & Swaby E Cohort analysis of Depo Provera users attending bone density scanning service at a district hospital. Osteoporosis Int (2014) 25 (Suppl 6):S659-S726

Athavale NV, Franke B, Thompson K & Swaby E Audit of Aromatase inhibitor users attending a local bone density scanning service in a district hospital. Osteoporosis Int (2014) 25 (Suppl 6):S659-S726