BEADS (Behavioural Activation Therapy for Depression after Stroke) Trial
CTRU and ScHARR staff have been awarded new HTA-funded pilot trial of Behavioural Activation therapy for post-stroke depression.
Cindy Cooper and Stephen Walters, in collaboration with Rebecca Palmer and Nick Latimer (ScHARR) and the Chief Investigator Shirley Thomas (University of Nottingham) and numerous co-applicants from University of Nottingham have been successful in being awarded £432k from the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme.
BEADS (Behavioural Activation therapy for Depression after Stroke) is a pilot randomised controlled trial to assess the feasibility of a study to investigate the clinical and cost-effectiveness of behavioural activation (BA) therapy for people with post-stroke depression.
The trial is due to open in May 2015, and we are aiming to recruit 72 people with post-stroke depression across three centres over 12 months. Participants will be randomised to receive BA or usual care.
Our key objectives are to assess the feasibility of proceeding to a definitive trial, and the feasibility of delivering BA to people with post-stroke depression. To address this, the study also incorporates qualitative research with participants, carers and therapists and an economic evaluation, and the primary clinical outcome measure is the PHQ-9 (Patient Health Questionnaire 9).
This work builds on the success of a previous study led by the Chief Investigator: CALM (Communication and Low Mood) which was funded by the Stroke Association to test BA for people with aphasia, and showed a positive impact on mood at 6 months.
Other CTRU staff involved in the BEADS trial include Lizzie Coates (Trial Manager), Helen Wakefield (Trial Support Officer), Tim Chater and Saleema Rex (Data Managers). Please contact Lizzie for more information.